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The map label for this gene is yfhM [H]

Identifier: 108801050

GI number: 108801050

Start: 4354792

End: 4355694

Strand: Reverse

Name: yfhM [H]

Synonym: Mmcs_4086

Alternate gene names: 108801050

Gene position: 4355694-4354792 (Counterclockwise)

Preceding gene: 108801051

Following gene: 108801048

Centisome position: 76.34

GC content: 72.98

Gene sequence:

>903_bases
ATGACGCCGCGCTGGTTGGATGTGGCGACCCCGGCCGGGCAGCTGCGGGCGCTGGTCTGGGGTCCGGAGGACGGTCCGGT
CGCGCTGTGCCTGCACGGCTTCCCCGACACCGCGTACGGATGGCGCAAACTCGCCCCCGCGCTCGCGGCTGCCGGATGGC
GGGTGGTGGCGCCGTTCATGCGTGGCTACGTGCCGTCGTCCGTCCCGTCCGACCGCAGCTATCACGTCGGGGCGTTGATG
GACGACGCCCTGCGCGTACTCGCCGCGGCGGGGCCGACGGGTCGCGACGTCATCATCGGACACGACTGGGGTGCGATCGC
CGGCACCGGTCTCGCCGCGATGCCGGACAGCCCCTTCGAACGGGCGGTCATCATGTCCGTGCCGCCGGCCGCGGCGTTCC
GTCCGCTCGGCCGCGTACCGGACAGGTGGCGGCTGGCCGCCGAGCTGCCCCGGCAGATGCTGCGCAGCTGGTACATCTTC
TACTTCCAGCTGCCCTGGCTGCCGGACCGGTCCGCGTCATGGGTGGTGCCCTGGCTGTGGCGGCAGTGGTCGCCCGGCTA
CCACGCCGCCGAGGACCTGCGACACGTCGACGCCGCCATCGGGGTGCGCCGGCGGTGGCGGGCCGCGCTGGGCTACTACC
GCGCCACCGTCCGCAACTCGCGGCCACCGGCGCAATACGCCGAACTGCACCGGCACTGGCTGTCGGCGCCGGTGTTGCCG
ACGCTGTACCTGCACGGCCACGACGACGGCTGCGCCACAGCGAATTTCACCCCCTGGGTGCAACGGGTGCTGCCCGAGGG
GAGTGCGGTCGCGGTCGTCGAGCACGCCGGGCACTTCCTGGCGCTCGAACAGCCCGACGTGGTCGGCCGCCACATCGTCG
ACTTCATCGGGACCGCCCGCTAG

Upstream 100 bases:

>100_bases
CCGTCGGCTCGGAACCCCCGACCAATACGGCCTCCAGCGTCCGGGTCACCCTCGACAAGGTCGGCGACCATTGGCGCGTG
TCCGAGTTCCAGCCGATCTG

Downstream 100 bases:

>100_bases
GAGCGCTTCATCCCGGGGTGGGCGCGGCCCAGCATCGGCAGCAGCAGGCGCCGCGGCGTGAGGTGGTTGAGCGCCGCGGC
GACCCGGTTCGGTGTGCCGG

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MTPRWLDVATPAGQLRALVWGPEDGPVALCLHGFPDTAYGWRKLAPALAAAGWRVVAPFMRGYVPSSVPSDRSYHVGALM
DDALRVLAAAGPTGRDVIIGHDWGAIAGTGLAAMPDSPFERAVIMSVPPAAAFRPLGRVPDRWRLAAELPRQMLRSWYIF
YFQLPWLPDRSASWVVPWLWRQWSPGYHAAEDLRHVDAAIGVRRRWRAALGYYRATVRNSRPPAQYAELHRHWLSAPVLP
TLYLHGHDDGCATANFTPWVQRVLPEGSAVAVVEHAGHFLALEQPDVVGRHIVDFIGTAR

Sequences:

>Translated_300_residues
MTPRWLDVATPAGQLRALVWGPEDGPVALCLHGFPDTAYGWRKLAPALAAAGWRVVAPFMRGYVPSSVPSDRSYHVGALM
DDALRVLAAAGPTGRDVIIGHDWGAIAGTGLAAMPDSPFERAVIMSVPPAAAFRPLGRVPDRWRLAAELPRQMLRSWYIF
YFQLPWLPDRSASWVVPWLWRQWSPGYHAAEDLRHVDAAIGVRRRWRAALGYYRATVRNSRPPAQYAELHRHWLSAPVLP
TLYLHGHDDGCATANFTPWVQRVLPEGSAVAVVEHAGHFLALEQPDVVGRHIVDFIGTAR
>Mature_299_residues
TPRWLDVATPAGQLRALVWGPEDGPVALCLHGFPDTAYGWRKLAPALAAAGWRVVAPFMRGYVPSSVPSDRSYHVGALMD
DALRVLAAAGPTGRDVIIGHDWGAIAGTGLAAMPDSPFERAVIMSVPPAAAFRPLGRVPDRWRLAAELPRQMLRSWYIFY
FQLPWLPDRSASWVVPWLWRQWSPGYHAAEDLRHVDAAIGVRRRWRAALGYYRATVRNSRPPAQYAELHRHWLSAPVLPT
LYLHGHDDGCATANFTPWVQRVLPEGSAVAVVEHAGHFLALEQPDVVGRHIVDFIGTAR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI218777837, Length=287, Percent_Identity=26.4808362369338, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI218777840, Length=170, Percent_Identity=30.5882352941176, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI13376164, Length=170, Percent_Identity=30.5882352941176, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI27597073, Length=83, Percent_Identity=42.1686746987952, Blast_Score=65, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17554012, Length=291, Percent_Identity=24.0549828178694, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17562298, Length=150, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: NA

Molecular weight: Translated: 33288; Mature: 33157

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: PS00104 EPSP_SYNTHASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPRWLDVATPAGQLRALVWGPEDGPVALCLHGFPDTAYGWRKLAPALAAAGWRVVAPFM
CCCCEEEECCCCCCEEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHH
RGYVPSSVPSDRSYHVGALMDDALRVLAAAGPTGRDVIIGHDWGAIAGTGLAAMPDSPFE
HCCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHCCCCCCCCCCCCC
RAVIMSVPPAAAFRPLGRVPDRWRLAAELPRQMLRSWYIFYFQLPWLPDRSASWVVPWLW
CEEEEECCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCEEEHHHH
RQWSPGYHAAEDLRHVDAAIGVRRRWRAALGYYRATVRNSRPPAQYAELHRHWLSAPVLP
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCE
TLYLHGHDDGCATANFTPWVQRVLPEGSAVAVVEHAGHFLALEQPDVVGRHIVDFIGTAR
EEEEECCCCCCCCCCCCHHHHHHCCCCCEEEEEECCCCEEEECCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TPRWLDVATPAGQLRALVWGPEDGPVALCLHGFPDTAYGWRKLAPALAAAGWRVVAPFM
CCCEEEECCCCCCEEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHH
RGYVPSSVPSDRSYHVGALMDDALRVLAAAGPTGRDVIIGHDWGAIAGTGLAAMPDSPFE
HCCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHCCCCCCCCCCCCC
RAVIMSVPPAAAFRPLGRVPDRWRLAAELPRQMLRSWYIFYFQLPWLPDRSASWVVPWLW
CEEEEECCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCEEEHHHH
RQWSPGYHAAEDLRHVDAAIGVRRRWRAALGYYRATVRNSRPPAQYAELHRHWLSAPVLP
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCE
TLYLHGHDDGCATANFTPWVQRVLPEGSAVAVVEHAGHFLALEQPDVVGRHIVDFIGTAR
EEEEECCCCCCCCCCCCHHHHHHCCCCCEEEEEECCCCEEEECCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]