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The map label for this gene is hsdM [C]

Identifier: 108800737

GI number: 108800737

Start: 4026083

End: 4027372

Strand: Reverse

Name: hsdM [C]

Synonym: Mmcs_3772

Alternate gene names: 108800737

Gene position: 4027372-4026083 (Counterclockwise)

Preceding gene: 108800738

Following gene: 108800736

Centisome position: 70.59

GC content: 62.02

Gene sequence:

>1290_bases
ATGCGGAGGGCACCGACCTCGAAGTCCAGTACACCAACATTCTGGTCGGGTTGGCCCAGCAACCCCGGAACGCTCGGAAC
CATCTACCGGAAGGCGCAGAACAGGGTTCAAGATCCGGCCAAGCTCAAGCGGCTGATCGTCGATCTCATCGACAAAGAGA
ACTGGTCCGCCTCGGGCACCGATCTCAAGGGCGACGCCTACGAGGAACTGCTTGCCAAGGGCGCCTCCGACAAGGGTTCT
GGGGCAGGTCAGTACTTCACGCCGCGCGACCTCATCCGCGCCATAGTGGACGTGATCGATCCGTCGGTGGCGGACACCGT
CGTCGACCCGGCGTGTGGCACTGGTGGCTTTCTTCTCGTTGCCCACGAGCACGTCGCGGAGGAGGCGGGAAAGCTCACCC
CAACGCAACGGAACCATCTGCGGGACAAATTCGTCACAGGGTATGAGCTCGTCGATGGCACTGCGCGACTGGCGGCGATG
AATTTACTGCTGCACGGAATCGGAACCGCAGACGGACCCTCGTTGATCGAGGTTCGGGATGCCTTGATAGCCGATCCAGG
GCAGCGTTGGTCGGTGGTGCTGTCCAACCCGCCATTCGGACGCAAGTCGTCGCTGACCATGGTCGGTGCCGACGGGCGGG
AAGCGCGCGACGATGTCGAGATCGAACGCCAAGACTTCGTCGTCACGACCAGCAACAAGCAGCTCAATTTTCTGCAGCAC
ATCATGACCATCCTCGACATCAACGGCCGCGCGGCCGTCGTCCTCCCTGACAACGTGCTATTCGAAGGCGGCGCCGGGGA
GACGCTGCGCCGAAAACTGCTGGACGACTTCGATCTTCACACCATGCTGCGCTTGCCGACCGGCATCTTCTACGCCCAGG
GCGTGAAGGCGAACGTGCTGTTCTTCGACAAAAGGCAGGCGAACGAGCAGCCGTGGACCAGCAAGCTGTGGGTTTACGAC
CTGCGCACCAACCAGCACTTCACGCTCAAACAGAACCGCTTGCGGCGGCATCACCTCGATGGGTTCGTCGACTCCTATTT
GACGGGAAAACCGCGTGAGGAGCGTGTCGAGTCGGAGCGGTGGAAAGCGTTCACCTATGACGACCTCATCGCCCGCGACA
AGGTGAATCTCGATATCACCTGGCTGCGCGACGAATCGTTGGAGGATGCTGACAACCTCCCGGCGCCGGAGGTGATCGCC
CGCGAGATCGTGGAGGATCTCACCGCGGCGCTGGCTGAATTCGAAGCCGTCGCGGCCGCGCTCGAAGCGGCAGCGACCGA
CCGCAGCTAA

Upstream 100 bases:

>100_bases
ACGTACCTACTGTTCTTGAAGATGGCCCACGAGCGGGCGACGCGGAAACTGAACCCGCAGAAGATCGTTCCCGACGAGTT
CTCTTGGCAGAAGCTCCTCG

Downstream 100 bases:

>100_bases
GCACTCTGGTCAATTCCCGAATCGGAGAATGATGTTCTCCCTTGCGGACAACGCCAGTATCGTGTGGGCGTGACGTTCGA
GCGCAAGACCTTGGTGGTCG

Product: N-6 DNA methylase

Products: NA

Alternate protein names: M.BthVORF4518P [H]

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MRRAPTSKSSTPTFWSGWPSNPGTLGTIYRKAQNRVQDPAKLKRLIVDLIDKENWSASGTDLKGDAYEELLAKGASDKGS
GAGQYFTPRDLIRAIVDVIDPSVADTVVDPACGTGGFLLVAHEHVAEEAGKLTPTQRNHLRDKFVTGYELVDGTARLAAM
NLLLHGIGTADGPSLIEVRDALIADPGQRWSVVLSNPPFGRKSSLTMVGADGREARDDVEIERQDFVVTTSNKQLNFLQH
IMTILDINGRAAVVLPDNVLFEGGAGETLRRKLLDDFDLHTMLRLPTGIFYAQGVKANVLFFDKRQANEQPWTSKLWVYD
LRTNQHFTLKQNRLRRHHLDGFVDSYLTGKPREERVESERWKAFTYDDLIARDKVNLDITWLRDESLEDADNLPAPEVIA
REIVEDLTAALAEFEAVAAALEAAATDRS

Sequences:

>Translated_429_residues
MRRAPTSKSSTPTFWSGWPSNPGTLGTIYRKAQNRVQDPAKLKRLIVDLIDKENWSASGTDLKGDAYEELLAKGASDKGS
GAGQYFTPRDLIRAIVDVIDPSVADTVVDPACGTGGFLLVAHEHVAEEAGKLTPTQRNHLRDKFVTGYELVDGTARLAAM
NLLLHGIGTADGPSLIEVRDALIADPGQRWSVVLSNPPFGRKSSLTMVGADGREARDDVEIERQDFVVTTSNKQLNFLQH
IMTILDINGRAAVVLPDNVLFEGGAGETLRRKLLDDFDLHTMLRLPTGIFYAQGVKANVLFFDKRQANEQPWTSKLWVYD
LRTNQHFTLKQNRLRRHHLDGFVDSYLTGKPREERVESERWKAFTYDDLIARDKVNLDITWLRDESLEDADNLPAPEVIA
REIVEDLTAALAEFEAVAAALEAAATDRS
>Mature_429_residues
MRRAPTSKSSTPTFWSGWPSNPGTLGTIYRKAQNRVQDPAKLKRLIVDLIDKENWSASGTDLKGDAYEELLAKGASDKGS
GAGQYFTPRDLIRAIVDVIDPSVADTVVDPACGTGGFLLVAHEHVAEEAGKLTPTQRNHLRDKFVTGYELVDGTARLAAM
NLLLHGIGTADGPSLIEVRDALIADPGQRWSVVLSNPPFGRKSSLTMVGADGREARDDVEIERQDFVVTTSNKQLNFLQH
IMTILDINGRAAVVLPDNVLFEGGAGETLRRKLLDDFDLHTMLRLPTGIFYAQGVKANVLFFDKRQANEQPWTSKLWVYD
LRTNQHFTLKQNRLRRHHLDGFVDSYLTGKPREERVESERWKAFTYDDLIARDKVNLDITWLRDESLEDADNLPAPEVIA
REIVEDLTAALAEFEAVAAALEAAATDRS

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790808, Length=439, Percent_Identity=37.3576309794989, Blast_Score=253, Evalue=1e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022749
- InterPro:   IPR003356
- InterPro:   IPR002052
- InterPro:   IPR002296 [H]

Pfam domain/function: PF12161 HsdM_N; PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 47648; Mature: 47648

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRAPTSKSSTPTFWSGWPSNPGTLGTIYRKAQNRVQDPAKLKRLIVDLIDKENWSASGT
CCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCC
DLKGDAYEELLAKGASDKGSGAGQYFTPRDLIRAIVDVIDPSVADTVVDPACGTGGFLLV
CCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHCCCCCCCCCEEEE
AHEHVAEEAGKLTPTQRNHLRDKFVTGYELVDGTARLAAMNLLLHGIGTADGPSLIEVRD
EEHHHHHHHCCCCCCHHHHHHHHHCCCHHHHCHHHHHHHHHHHHHHCCCCCCCHHHHHHH
ALIADPGQRWSVVLSNPPFGRKSSLTMVGADGREARDDVEIERQDFVVTTSNKQLNFLQH
HHHCCCCCCEEEEECCCCCCCCCCEEEEECCCCCCCCCCCEECCCEEEEECCCHHHHHHH
IMTILDINGRAAVVLPDNVLFEGGAGETLRRKLLDDFDLHTMLRLPTGIFYAQGVKANVL
HHHHHCCCCCEEEEECCCEEEECCCCHHHHHHHHHHCCHHHHHHCCCCCEEECCCEEEEE
FFDKRQANEQPWTSKLWVYDLRTNQHFTLKQNRLRRHHLDGFVDSYLTGKPREERVESER
EEECCCCCCCCCCCEEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
WKAFTYDDLIARDKVNLDITWLRDESLEDADNLPAPEVIAREIVEDLTAALAEFEAVAAA
CCEECHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LEAAATDRS
HHHHHCCCC
>Mature Secondary Structure
MRRAPTSKSSTPTFWSGWPSNPGTLGTIYRKAQNRVQDPAKLKRLIVDLIDKENWSASGT
CCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCC
DLKGDAYEELLAKGASDKGSGAGQYFTPRDLIRAIVDVIDPSVADTVVDPACGTGGFLLV
CCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHCCCCCCCCCEEEE
AHEHVAEEAGKLTPTQRNHLRDKFVTGYELVDGTARLAAMNLLLHGIGTADGPSLIEVRD
EEHHHHHHHCCCCCCHHHHHHHHHCCCHHHHCHHHHHHHHHHHHHHCCCCCCCHHHHHHH
ALIADPGQRWSVVLSNPPFGRKSSLTMVGADGREARDDVEIERQDFVVTTSNKQLNFLQH
HHHCCCCCCEEEEECCCCCCCCCCEEEEECCCCCCCCCCCEECCCEEEEECCCHHHHHHH
IMTILDINGRAAVVLPDNVLFEGGAGETLRRKLLDDFDLHTMLRLPTGIFYAQGVKANVL
HHHHHCCCCCEEEEECCCEEEECCCCHHHHHHHHHHCCHHHHHHCCCCCEEECCCEEEEE
FFDKRQANEQPWTSKLWVYDLRTNQHFTLKQNRLRRHHLDGFVDSYLTGKPREERVESER
EEECCCCCCCCCCCEEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
WKAFTYDDLIARDKVNLDITWLRDESLEDADNLPAPEVIAREIVEDLTAALAEFEAVAAA
CCEECHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LEAAATDRS
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12663928 [H]