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The map label for this gene is dmpD [H]

Identifier: 108800736

GI number: 108800736

Start: 4025171

End: 4026019

Strand: Reverse

Name: dmpD [H]

Synonym: Mmcs_3771

Alternate gene names: 108800736

Gene position: 4026019-4025171 (Counterclockwise)

Preceding gene: 108800737

Following gene: 108800735

Centisome position: 70.56

GC content: 70.44

Gene sequence:

>849_bases
GTGGGCGTGACGTTCGAGCGCAAGACCTTGGTGGTCGACGGACTGCGCACCAGCTACCTGGAAGCGGGAACCGGGGACTC
GGTGGTTCTGCTGCACGGCGGCGAGTTCGGCGCGTCGGCCGAACTCGGCTGGGAGCGGGTGATCGGCGCACTGGCCGAGC
GGTATCACGTGCTCGCGCCCGACATGCTGGGGTTCGGCCGGTCGGCGAAGGTCGTCGACTTCACCGACGGCCGCGGGATG
CGCATCCGCCACATCGCGCGCTTCTGCGAGGTCCTCGACGTGGGGTCGGCGCATTTCGTCGGCAACTCGATGGGCGCGAT
CAACCTGCTCGTCGACGCCACGTCGGGCGCGCCCGTGCTGCCCGCGCGCAGCCTCGTCGCACTGTGCGGCGGCGGGACCA
TCCAGCGCAACGAACACGCCAACGCCCTCTACGACTACGACGCGACGCCGGACGGGATGCGCAGGATCGTCACCGCGCTG
TTCGCCGATCCGTCGTATCCGGCCGACGACGACTACGTCGGTCGACGCTACGAGTCGTCGATCGCCCCGGGCGCTTGGGA
GTCGTTGGCGGCAGCCCGGTTTCGCCGGCCCGGTCTGGAACCGCCACCGCCCCCGTCGGCCACCCGGCCGTACGAGCGCA
TCACCGTGCCCACGCTGATCGTCGAAGGGGAACGCGACAAACTGCTGCCGGCCGGGTGGGCCGCCGAGATCGCCGGACAG
ATCACCCGTGCGCGGTCCGCGGTCGTCCCGGCCGCCGGGCACTGCCCGCAGATCGAACAACCGGCCGCGGTCACCGATCT
GCTCCTCGAATTCTTCGCCGACGTCCCTCAACGAAAGGTGTCCGCCTGA

Upstream 100 bases:

>100_bases
GGCCGCGCTCGAAGCGGCAGCGACCGACCGCAGCTAAGCACTCTGGTCAATTCCCGAATCGGAGAATGATGTTCTCCCTT
GCGGACAACGCCAGTATCGT

Downstream 100 bases:

>100_bases
TGGTCACTAGACCCAATGACGAACTGCACGGGCGGGTCGCGATCGTCACCGGTGGCGCGTCGGGGATCGGCCGCGGCGTC
GCCGAACGGTTCGTCGCCGA

Product: alpha/beta hydrolase fold protein

Products: 2-oxopent-4-enoate; succinate [C]

Alternate protein names: HMSH [H]

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MGVTFERKTLVVDGLRTSYLEAGTGDSVVLLHGGEFGASAELGWERVIGALAERYHVLAPDMLGFGRSAKVVDFTDGRGM
RIRHIARFCEVLDVGSAHFVGNSMGAINLLVDATSGAPVLPARSLVALCGGGTIQRNEHANALYDYDATPDGMRRIVTAL
FADPSYPADDDYVGRRYESSIAPGAWESLAAARFRRPGLEPPPPPSATRPYERITVPTLIVEGERDKLLPAGWAAEIAGQ
ITRARSAVVPAAGHCPQIEQPAAVTDLLLEFFADVPQRKVSA

Sequences:

>Translated_282_residues
MGVTFERKTLVVDGLRTSYLEAGTGDSVVLLHGGEFGASAELGWERVIGALAERYHVLAPDMLGFGRSAKVVDFTDGRGM
RIRHIARFCEVLDVGSAHFVGNSMGAINLLVDATSGAPVLPARSLVALCGGGTIQRNEHANALYDYDATPDGMRRIVTAL
FADPSYPADDDYVGRRYESSIAPGAWESLAAARFRRPGLEPPPPPSATRPYERITVPTLIVEGERDKLLPAGWAAEIAGQ
ITRARSAVVPAAGHCPQIEQPAAVTDLLLEFFADVPQRKVSA
>Mature_281_residues
GVTFERKTLVVDGLRTSYLEAGTGDSVVLLHGGEFGASAELGWERVIGALAERYHVLAPDMLGFGRSAKVVDFTDGRGMR
IRHIARFCEVLDVGSAHFVGNSMGAINLLVDATSGAPVLPARSLVALCGGGTIQRNEHANALYDYDATPDGMRRIVTALF
ADPSYPADDDYVGRRYESSIAPGAWESLAAARFRRPGLEPPPPPSATRPYERITVPTLIVEGERDKLLPAGWAAEIAGQI
TRARSAVVPAAGHCPQIEQPAAVTDLLLEFFADVPQRKVSA

Specific function: Conversion of 2-hydroxymuconic acid semialdehyde to 2- hydroxypent-2,4-dienoate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dmpD/todF/xylF esterase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: 3.7.1.- [C]

Molecular weight: Translated: 30181; Mature: 30049

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVTFERKTLVVDGLRTSYLEAGTGDSVVLLHGGEFGASAELGWERVIGALAERYHVLAP
CCCCCCCCEEEECCHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCC
DMLGFGRSAKVVDFTDGRGMRIRHIARFCEVLDVGSAHFVGNSMGAINLLVDATSGAPVL
HHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCC
PARSLVALCGGGTIQRNEHANALYDYDATPDGMRRIVTALFADPSYPADDDYVGRRYESS
CHHHHHHHHCCCCEECCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCCHHCCHHHCC
IAPGAWESLAAARFRRPGLEPPPPPSATRPYERITVPTLIVEGERDKLLPAGWAAEIAGQ
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHEEEEEEEEECCCCCCCCCCHHHHHHHH
ITRARSAVVPAAGHCPQIEQPAAVTDLLLEFFADVPQRKVSA
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHCCC
>Mature Secondary Structure 
GVTFERKTLVVDGLRTSYLEAGTGDSVVLLHGGEFGASAELGWERVIGALAERYHVLAP
CCCCCCCEEEECCHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCC
DMLGFGRSAKVVDFTDGRGMRIRHIARFCEVLDVGSAHFVGNSMGAINLLVDATSGAPVL
HHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCC
PARSLVALCGGGTIQRNEHANALYDYDATPDGMRRIVTALFADPSYPADDDYVGRRYESS
CHHHHHHHHCCCCEECCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCCHHCCHHHCC
IAPGAWESLAAARFRRPGLEPPPPPSATRPYERITVPTLIVEGERDKLLPAGWAAEIAGQ
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHEEEEEEEEECCCCCCCCCCHHHHHHHH
ITRARSAVVPAAGHCPQIEQPAAVTDLLLEFFADVPQRKVSA
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-hydroxy-6-ketononadienedicarboxylate; H2O [C]

Specific reaction: 2-hydroxy-6-ketononadienedicarboxylate + H2O = 2-oxopent-4-enoate + succinate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2194577 [H]