BacMap

Definition	Mycobacterium sp. MCS chromosome, complete genome.
Accession	NC_008146
Length	5,705,448

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The map label for this gene is fabG [H]

Identifier: 108800676

GI number: 108800676

Start: 3964022

End: 3964765

Strand: Reverse

Name: fabG [H]

Synonym: Mmcs_3711

Alternate gene names: 108800676

Gene position: 3964765-3964022 (Counterclockwise)

Preceding gene: 108800677

Following gene: 108800675

Centisome position: 69.49

GC content: 67.74

Gene sequence:

>744_bases
ATGACACGGGTAGCGGTGGTGACCGGCGGCGCCTCGGGCATGGGGGAGGCGATCTGTCACGAGCTCGGCAGGCGCGGACA
CCGGGTCGCCGTGCTCGACCTCAACGGCGATGCGGCGCAACGTGTCACCGAAGACCTACGCGCCGAGGGCGTGACCGCGC
TGGGCGTGGCCGCCGACGTCAGCAACCGCGCCGCGGTGGAGGAGGCCTTCGCCAAGGTACGCACCGAACTCGGCCCGGTG
CACATCCTGGTCACCAGTGCCGGGCTGGTGGATTTCGCACCGTTCCTCGAGATCACTCCGCAGGCCTGGCAGAAGCTCAT
CGACGTCAACCTCACCGGAACGTTCCACTGTTGTCAGGTCGCGGTGCCGGACATGCTCGAGGCGGGGTGGGGGCGGATCG
TGATGATCTCGTCGTCGAGCGCCCAGCGCGGTTCGCCCAAGATGGCGCACTACGCCGCATCGAAAGGTGCGCTGATCTCG
TTGACCAAATCGCTGGCGCGCGAATACGGACCGACCGGCATCACGGTCAACAACGTCCCGCCGTCGGGTATCGAGACGCC
GATGCAACACCACTCGCAGGCCGCCGGTCACCTGCCGCCCAACGAGCAGATGGCCGCCAGCATCCCGGTGGGCCACCTCG
GAACCGGCGACGACATCGCCGCCGCGGTCGGTTTCCTGTGCTCCAACGAGGCGGGATTCATCACCGGTCAGGTGCTCGGA
GTCAACGGCGGATCGGTGCTGTGA

Upstream 100 bases:

>100_bases
GCGCTCGACGACGACGAGGTGGCCGACGGCTGGGTGCTGACCTGCCAATCGCTGCCGACGAGTCGATCAGTGCACGTGGT
CTACGAGTAGAGGTGAAGCG

Downstream 100 bases:

>100_bases
TGCCGCACCACGCAATGCAACGACAGGGAGGTTCGCATGGGGCGCTGGCCTAAACCGCCGGAAGGCAGTTGGACGGAGCA
CTATCCCGAACTCGGCACCG

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MTRVAVVTGGASGMGEAICHELGRRGHRVAVLDLNGDAAQRVTEDLRAEGVTALGVAADVSNRAAVEEAFAKVRTELGPV
HILVTSAGLVDFAPFLEITPQAWQKLIDVNLTGTFHCCQVAVPDMLEAGWGRIVMISSSSAQRGSPKMAHYAASKGALIS
LTKSLAREYGPTGITVNNVPPSGIETPMQHHSQAAGHLPPNEQMAASIPVGHLGTGDDIAAAVGFLCSNEAGFITGQVLG
VNGGSVL

Sequences:

>Translated_247_residues
MTRVAVVTGGASGMGEAICHELGRRGHRVAVLDLNGDAAQRVTEDLRAEGVTALGVAADVSNRAAVEEAFAKVRTELGPV
HILVTSAGLVDFAPFLEITPQAWQKLIDVNLTGTFHCCQVAVPDMLEAGWGRIVMISSSSAQRGSPKMAHYAASKGALIS
LTKSLAREYGPTGITVNNVPPSGIETPMQHHSQAAGHLPPNEQMAASIPVGHLGTGDDIAAAVGFLCSNEAGFITGQVLG
VNGGSVL
>Mature_246_residues
TRVAVVTGGASGMGEAICHELGRRGHRVAVLDLNGDAAQRVTEDLRAEGVTALGVAADVSNRAAVEEAFAKVRTELGPVH
ILVTSAGLVDFAPFLEITPQAWQKLIDVNLTGTFHCCQVAVPDMLEAGWGRIVMISSSSAQRGSPKMAHYAASKGALISL
TKSLAREYGPTGITVNNVPPSGIETPMQHHSQAAGHLPPNEQMAASIPVGHLGTGDDIAAAVGFLCSNEAGFITGQVLGV
NGGSVL

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=252, Percent_Identity=35.3174603174603, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI32483357, Length=244, Percent_Identity=31.5573770491803, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI40254992, Length=244, Percent_Identity=31.1475409836066, Blast_Score=114, Evalue=5e-26,
Organism=Homo sapiens, GI19923817, Length=250, Percent_Identity=28.8, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI7705925, Length=246, Percent_Identity=32.520325203252, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI5031737, Length=245, Percent_Identity=31.8367346938775, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI126723750, Length=248, Percent_Identity=28.6290322580645, Blast_Score=94, Evalue=9e-20,
Organism=Homo sapiens, GI4504505, Length=192, Percent_Identity=33.8541666666667, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI210032110, Length=186, Percent_Identity=29.0322580645161, Blast_Score=91, Evalue=7e-19,
Organism=Homo sapiens, GI10190704, Length=250, Percent_Identity=29.6, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI4503817, Length=187, Percent_Identity=28.3422459893048, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI33667109, Length=185, Percent_Identity=34.0540540540541, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI4758504, Length=255, Percent_Identity=29.4117647058824, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI66933014, Length=228, Percent_Identity=26.7543859649123, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI59889578, Length=228, Percent_Identity=30.2631578947368, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI226371731, Length=257, Percent_Identity=28.4046692607004, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI40807363, Length=190, Percent_Identity=28.4210526315789, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI126723191, Length=176, Percent_Identity=30.1136363636364, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI7705855, Length=246, Percent_Identity=25.609756097561, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI83715985, Length=183, Percent_Identity=31.1475409836066, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI4503301, Length=194, Percent_Identity=27.8350515463918, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI142976729, Length=187, Percent_Identity=24.0641711229947, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI310128830, Length=214, Percent_Identity=28.9719626168224, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI310115468, Length=214, Percent_Identity=28.9719626168224, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI7706318, Length=199, Percent_Identity=27.6381909547739, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI31542939, Length=193, Percent_Identity=26.4248704663212, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI109715829, Length=247, Percent_Identity=25.9109311740891, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI1787335, Length=245, Percent_Identity=37.9591836734694, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI87082100, Length=250, Percent_Identity=31.6, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1788459, Length=249, Percent_Identity=33.3333333333333, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1790717, Length=246, Percent_Identity=28.8617886178862, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI2367175, Length=248, Percent_Identity=33.8709677419355, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1789057, Length=258, Percent_Identity=31.0077519379845, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787905, Length=245, Percent_Identity=31.8367346938775, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI87082160, Length=245, Percent_Identity=27.7551020408163, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1789208, Length=247, Percent_Identity=27.1255060728745, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1789378, Length=249, Percent_Identity=30.5220883534137, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI2367365, Length=243, Percent_Identity=31.6872427983539, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786812, Length=247, Percent_Identity=27.9352226720648, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1787820, Length=180, Percent_Identity=29.4444444444444, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1787526, Length=196, Percent_Identity=29.5918367346939, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=247, Percent_Identity=35.6275303643725, Blast_Score=127, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17555706, Length=246, Percent_Identity=34.1463414634146, Blast_Score=123, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI17560676, Length=244, Percent_Identity=31.1475409836066, Blast_Score=112, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17561402, Length=245, Percent_Identity=29.7959183673469, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17568967, Length=192, Percent_Identity=32.8125, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=27.8884462151394, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI115534694, Length=240, Percent_Identity=30.4166666666667, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI71994604, Length=251, Percent_Identity=29.0836653386454, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17567345, Length=190, Percent_Identity=28.9473684210526, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI193203117, Length=166, Percent_Identity=30.7228915662651, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17538182, Length=197, Percent_Identity=33.502538071066, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI193203115, Length=166, Percent_Identity=30.7228915662651, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17562906, Length=266, Percent_Identity=27.4436090225564, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17561272, Length=246, Percent_Identity=30.4878048780488, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17536025, Length=246, Percent_Identity=26.8292682926829, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17536651, Length=246, Percent_Identity=26.4227642276423, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17508651, Length=245, Percent_Identity=28.1632653061224, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17564282, Length=191, Percent_Identity=26.1780104712042, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17559104, Length=266, Percent_Identity=26.3157894736842, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=263, Percent_Identity=26.9961977186312, Blast_Score=77, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17531453, Length=259, Percent_Identity=26.6409266409266, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17508895, Length=200, Percent_Identity=24.5, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=263, Percent_Identity=26.2357414448669, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=27.3764258555133, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562910, Length=259, Percent_Identity=25.0965250965251, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=262, Percent_Identity=26.3358778625954, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=263, Percent_Identity=25.4752851711027, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17544670, Length=268, Percent_Identity=25.7462686567164, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=257, Percent_Identity=26.4591439688716, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=262, Percent_Identity=25.9541984732824, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=262, Percent_Identity=26.3358778625954, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=24.8091603053435, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17538486, Length=269, Percent_Identity=26.7657992565056, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=246, Percent_Identity=28.4552845528455, Blast_Score=97, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6322861, Length=192, Percent_Identity=30.7291666666667, Blast_Score=87, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320089, Length=191, Percent_Identity=26.7015706806283, Blast_Score=71, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24639444, Length=247, Percent_Identity=33.6032388663968, Blast_Score=121, Evalue=4e-28,
Organism=Drosophila melanogaster, GI21355319, Length=246, Percent_Identity=30.4878048780488, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI21357041, Length=245, Percent_Identity=28.1632653061224, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24643142, Length=244, Percent_Identity=31.5573770491803, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=29.4820717131474, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28571526, Length=245, Percent_Identity=26.9387755102041, Blast_Score=94, Evalue=6e-20,
Organism=Drosophila melanogaster, GI18859837, Length=189, Percent_Identity=34.3915343915344, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24644339, Length=253, Percent_Identity=27.2727272727273, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24649181, Length=187, Percent_Identity=34.2245989304813, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24640492, Length=188, Percent_Identity=26.063829787234, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21356301, Length=196, Percent_Identity=29.5918367346939, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24641232, Length=198, Percent_Identity=30.3030303030303, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24581726, Length=190, Percent_Identity=28.4210526315789, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI17737361, Length=255, Percent_Identity=27.4509803921569, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21355631, Length=167, Percent_Identity=31.1377245508982, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24644337, Length=231, Percent_Identity=28.1385281385281, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21358495, Length=192, Percent_Identity=29.1666666666667, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI221510726, Length=229, Percent_Identity=25.764192139738, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI116007236, Length=196, Percent_Identity=28.0612244897959, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24584752, Length=228, Percent_Identity=27.6315789473684, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641388, Length=238, Percent_Identity=27.3109243697479, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI116007238, Length=203, Percent_Identity=26.6009852216749, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281364892, Length=219, Percent_Identity=25.5707762557078, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI161076371, Length=200, Percent_Identity=26, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24584748, Length=221, Percent_Identity=28.0542986425339, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI161076933, Length=221, Percent_Identity=28.0542986425339, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25479; Mature: 25348

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRVAVVTGGASGMGEAICHELGRRGHRVAVLDLNGDAAQRVTEDLRAEGVTALGVAADV
CCEEEEEECCCCCHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHCCCEEEEEECCC
SNRAAVEEAFAKVRTELGPVHILVTSAGLVDFAPFLEITPQAWQKLIDVNLTGTFHCCQV
CCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEHH
AVPDMLEAGWGRIVMISSSSAQRGSPKMAHYAASKGALISLTKSLAREYGPTGITVNNVP
CCHHHHHCCCCEEEEEECCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHCCCCEEECCCC
PSGIETPMQHHSQAAGHLPPNEQMAASIPVGHLGTGDDIAAAVGFLCSNEAGFITGQVLG
CCCCCCHHHHHHHCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEE
VNGGSVL
CCCCCCC
>Mature Secondary Structure 
TRVAVVTGGASGMGEAICHELGRRGHRVAVLDLNGDAAQRVTEDLRAEGVTALGVAADV
CEEEEEECCCCCHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHCCCEEEEEECCC
SNRAAVEEAFAKVRTELGPVHILVTSAGLVDFAPFLEITPQAWQKLIDVNLTGTFHCCQV
CCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEHH
AVPDMLEAGWGRIVMISSSSAQRGSPKMAHYAASKGALISLTKSLAREYGPTGITVNNVP
CCHHHHHCCCCEEEEEECCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHCCCCEEECCCC
PSGIETPMQHHSQAAGHLPPNEQMAASIPVGHLGTGDDIAAAVGFLCSNEAGFITGQVLG
CCCCCCHHHHHHHCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEE
VNGGSVL
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA