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The map label for this gene is clpX [H]

Identifier: 108800542

GI number: 108800542

Start: 3807952

End: 3809232

Strand: Reverse

Name: clpX [H]

Synonym: Mmcs_3576

Alternate gene names: 108800542

Gene position: 3809232-3807952 (Counterclockwise)

Preceding gene: 108800543

Following gene: 108800535

Centisome position: 66.76

GC content: 64.72

Gene sequence:

>1281_bases
ATGGCGCGCATTGGAGACGGCGGTGACCTGCTGAAGTGCTCGTTCTGCGGGAAGAGTCAGAAGCAGGTCAAGAAGCTGAT
CGCGGGCCCCGGCGTATACATCTGTGACGAGTGCATCGATCTCTGCAACGAGATCATCGAAGAGGAACTGGCCGACGCCG
ACGAGGTGAAACTCGACGAGCTGCCCAAGCCCGCGGAGATCCGCGAGTTCCTCGAGAACTACGTCATCGGACAGGACACC
GCCAAGCGCACCCTGGCCGTCGCCGTCTACAACCATTACAAGCGCATCCAGGCCGGCGAGAAGAGCCGCGATTCGCGCAC
CGAGCCCGTCGAGTTGACCAAGTCCAACATCCTGATGCTGGGCCCGACCGGCTGCGGTAAGACCTACCTCGCCCAGACGC
TGGCCAAGATGCTCAACGTGCCGTTCGCGATCGCCGACGCCACGGCGCTGACCGAAGCCGGCTACGTCGGTGAGGACGTC
GAGAACATCCTGCTGAAGCTGATCCAGGCCGCCGACTACGACGTCAAGCGCGCCGAGACCGGCATCATCTACATCGACGA
GGTCGACAAGATCGCCCGCAAGAGCGAGAACCCGTCGATCACCCGCGACGTCTCCGGCGAAGGTGTGCAGCAGGCGCTGC
TCAAGATCCTCGAGGGCACGCAGGCGTCGGTGCCTCCGCAGGGCGGGCGCAAGCACCCCCACCAGGAGTTCATCCAGATC
GACACCACCAACGTGCTGTTCATCGTCGCGGGTGCGTTCGCCGGTCTGGAGAAGATCGTCTCCGACCGCGTCGGCAAGCG
CGGCCTCGGCTTCGGCGCGGAGGTCCGCTCCAAGGCCGAGATCGACACCCAGGACCACTTCGCCGAGGTCATGCCCGAGG
ACCTGATCAAGTTCGGTCTGATCCCCGAGTTCATCGGCCGGTTGCCGGTCGTGGCGTCGGTGACCAACCTCGACAAGGAG
TCGTTGGTCAAGATCCTGTCGGAGCCGAAGAACGCGTTGGTCAAGCAGTACACGCGGCTGTTCGAGATGGACGGCGTCGA
GCTGGAGTTCACCGGTGACGCGCTGGACGCCATCGCCGATCAGGCCATCCACCGCGGCACCGGCGCCCGTGGCCTGCGCG
CCATCATGGAGGAAGTCCTGCTGCCGGTGATGTACGACATCCCCAGCCGCGACGACGTCGCGAAGGTCGTCGTCACCAAG
GAGACCGTGCAGGACAACGTGCTGCCGACGATCGTGCCGCGTAAGCCGTCACGCCCCGAGCGTCGCGACAAGAGCGCCTA
G

Upstream 100 bases:

>100_bases
CGAGTTAACGGGTAGCGTCGGGAACAGGGCCCCATCACAGGTCCTCTCAACGACCCGAACGACCCACCGACGTCGAACAG
GAAAGTAGGACCCCACCACC

Downstream 100 bases:

>100_bases
GCTCACGCCGAGATTGCACTGAGGGTCGTGAACCGCGAAGGTTCACGACCCTCAGTGCATTTTCGCGACGGTGAACCGGT
TCGGTAGCGCGTATCGGTGG

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEELADADEVKLDELPKPAEIREFLENYVIGQDT
AKRTLAVAVYNHYKRIQAGEKSRDSRTEPVELTKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATALTEAGYVGEDV
ENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPSITRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQI
DTTNVLFIVAGAFAGLEKIVSDRVGKRGLGFGAEVRSKAEIDTQDHFAEVMPEDLIKFGLIPEFIGRLPVVASVTNLDKE
SLVKILSEPKNALVKQYTRLFEMDGVELEFTGDALDAIADQAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVTK
ETVQDNVLPTIVPRKPSRPERRDKSA

Sequences:

>Translated_426_residues
MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEELADADEVKLDELPKPAEIREFLENYVIGQDT
AKRTLAVAVYNHYKRIQAGEKSRDSRTEPVELTKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATALTEAGYVGEDV
ENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPSITRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQI
DTTNVLFIVAGAFAGLEKIVSDRVGKRGLGFGAEVRSKAEIDTQDHFAEVMPEDLIKFGLIPEFIGRLPVVASVTNLDKE
SLVKILSEPKNALVKQYTRLFEMDGVELEFTGDALDAIADQAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVTK
ETVQDNVLPTIVPRKPSRPERRDKSA
>Mature_425_residues
ARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEELADADEVKLDELPKPAEIREFLENYVIGQDTA
KRTLAVAVYNHYKRIQAGEKSRDSRTEPVELTKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATALTEAGYVGEDVE
NILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPSITRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQID
TTNVLFIVAGAFAGLEKIVSDRVGKRGLGFGAEVRSKAEIDTQDHFAEVMPEDLIKFGLIPEFIGRLPVVASVTNLDKES
LVKILSEPKNALVKQYTRLFEMDGVELEFTGDALDAIADQAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVTKE
TVQDNVLPTIVPRKPSRPERRDKSA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=346, Percent_Identity=49.4219653179191, Blast_Score=305, Evalue=4e-83,
Organism=Escherichia coli, GI1786642, Length=412, Percent_Identity=62.621359223301, Blast_Score=526, Evalue=1e-150,
Organism=Escherichia coli, GI1790366, Length=108, Percent_Identity=47.2222222222222, Blast_Score=102, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI71982908, Length=310, Percent_Identity=45.1612903225806, Blast_Score=272, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI71982905, Length=312, Percent_Identity=45.5128205128205, Blast_Score=272, Evalue=3e-73,
Organism=Caenorhabditis elegans, GI71988663, Length=426, Percent_Identity=36.8544600938967, Blast_Score=245, Evalue=3e-65,
Organism=Caenorhabditis elegans, GI71988660, Length=261, Percent_Identity=39.0804597701149, Blast_Score=166, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6319704, Length=428, Percent_Identity=39.018691588785, Blast_Score=278, Evalue=8e-76,
Organism=Drosophila melanogaster, GI24648291, Length=330, Percent_Identity=46.0606060606061, Blast_Score=290, Evalue=9e-79,
Organism=Drosophila melanogaster, GI24648289, Length=330, Percent_Identity=46.0606060606061, Blast_Score=290, Evalue=1e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46745; Mature: 46614

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEELADADEVKLDE
CCCCCCCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHC
LPKPAEIREFLENYVIGQDTAKRTLAVAVYNHYKRIQAGEKSRDSRTEPVELTKSNILML
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCEEEE
GPTGCGKTYLAQTLAKMLNVPFAIADATALTEAGYVGEDVENILLKLIQAADYDVKRAET
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHCCC
GIIYIDEVDKIARKSENPSITRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQI
CEEEECCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHEEE
DTTNVLFIVAGAFAGLEKIVSDRVGKRGLGFGAEVRSKAEIDTQDHFAEVMPEDLIKFGL
CCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCHHHHHHHHCHHHHHHHCC
IPEFIGRLPVVASVTNLDKESLVKILSEPKNALVKQYTRLFEMDGVELEFTGDALDAIAD
HHHHHCCCCHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHH
QAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVTKETVQDNVLPTIVPRKPSRPE
HHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHEEEHHHHHCCCCCCCCCCCCCCCC
RRDKSA
CCCCCC
>Mature Secondary Structure 
ARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEELADADEVKLDE
CCCCCCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHC
LPKPAEIREFLENYVIGQDTAKRTLAVAVYNHYKRIQAGEKSRDSRTEPVELTKSNILML
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCEEEE
GPTGCGKTYLAQTLAKMLNVPFAIADATALTEAGYVGEDVENILLKLIQAADYDVKRAET
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHCCC
GIIYIDEVDKIARKSENPSITRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQI
CEEEECCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHEEE
DTTNVLFIVAGAFAGLEKIVSDRVGKRGLGFGAEVRSKAEIDTQDHFAEVMPEDLIKFGL
CCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCHHHHHHHHCHHHHHHHCC
IPEFIGRLPVVASVTNLDKESLVKILSEPKNALVKQYTRLFEMDGVELEFTGDALDAIAD
HHHHHCCCCHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHH
QAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVTKETVQDNVLPTIVPRKPSRPE
HHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHEEEHHHHHCCCCCCCCCCCCCCCC
RRDKSA
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA