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The map label for this gene is murG [H]

Identifier: 108800222

GI number: 108800222

Start: 3450610

End: 3451731

Strand: Reverse

Name: murG [H]

Synonym: Mmcs_3256

Alternate gene names: 108800222

Gene position: 3451731-3450610 (Counterclockwise)

Preceding gene: 108800223

Following gene: 108800221

Centisome position: 60.5

GC content: 73.62

Gene sequence:

>1122_bases
GTGAACGGCACCATCTCGGTCCTCCTCGCCGGCGGCGGAACCGCGGGGCACGTCGAACCGGCGATGGCCGTCGCCGACGC
GCTGGCCGCGCTGGAGCCCGGGGTGCGGATCACCGCACTCGGCACCGAGCGGGGGCTGGAGACGCGACTGGTTCCCGAGC
GCGGCTACGCCCTGGAACTGATCACGCCGGTCCCGCTGCCCCGCAAACTGTCGGGTGATCTCGCCCGGTTGCCGATGCGC
GTGCGCCGGGCCGTGCGGGAGACCCGCGAAATCCTCGACACCGTGCACGCCGACGTCGTGATCGGGTTCGGCGGTTACGT
GGCGCTGCCCGCGTACCTGGCCGCCCGGCGCAACAGGGTGCCCATCGTCGTCCACGAGGCCAATGCCAGCGCGGGTCTGG
CCAACAAGGTCGGCGCCCGGTTCGCCCGCCGGGTGCTGTCCGCCGTGGCCGACCCCGGCCTGGGCCGGGTGGAGGTGGTC
GGTACGCCGGTGCGTTCGAGCATCACCGAACTGGACCGCGCCGCACTGCGTGCCGAGGCGCGCGCCCACTTCGGATTCGC
CGACGACGCCCGCGTCCTGTTGGTGTTCGGCGGGTCGCAGGGCGCCCGCTCCCTCAACAACGTCGTCTCCGGCGCAGCGA
AAGCGCTTGCTGCAGCGGGGATTTCGGTGCTGCACGCGTACGGGGCGAAGAACACCCTCGAGCTGCCGGACCCGGCGCCG
GGGGATCCGCCGTATGTCGCGGTGCCGTATCTGAGCCGGATGGACCTGGCGTATGCGGCCGCCGACCTGGCGATCTGCCG
GTCCGGGGCGATGACCGTGGCCGAGGTGACCGCGGTCGGGCTCCCCGCGGTGTACGTGCCGCTGCCGATCGGCAACGGTG
AACAGCGGCTCAACGCCCGGCCGGTCGTCGAGACGGGCGGCGGCCTGGTGGTCGACGACGCCGACCTGTCACCGCAGTTC
GTCGCCGACACGGTCGTCCCGCTGCTCACCGACACCGGGCGACTGCAGACCATGACCGCGGGAGCCGCGCTGTCCGGGCA
CCGGGATGCGGCCCGGCACGTCGCCCACGTGGCGCTCGACGTGGCGCGCGAAGCGGCCGGCGGGCGGAAGGGGGTGCGGT
GA

Upstream 100 bases:

>100_bases
GCGGTCAGCGGTCGGCAACGCGCCGGACCGGTCAGGATCAACAGGGTCGGCGGGGCCAACAGGGCCGGCGAGCCCGCCCC
AGGGAAGGTCAACGTTACGG

Downstream 100 bases:

>100_bases
GCACCCCACCCCTGCCCGACGAACTGCGCCGGGTCCACATGGTCGGCATCGGGGGCGCGGGAATGTCGGGCATCGCGCGC
ATCCTGCTCGACCGCGGGGC

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase [H]

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MNGTISVLLAGGGTAGHVEPAMAVADALAALEPGVRITALGTERGLETRLVPERGYALELITPVPLPRKLSGDLARLPMR
VRRAVRETREILDTVHADVVIGFGGYVALPAYLAARRNRVPIVVHEANASAGLANKVGARFARRVLSAVADPGLGRVEVV
GTPVRSSITELDRAALRAEARAHFGFADDARVLLVFGGSQGARSLNNVVSGAAKALAAAGISVLHAYGAKNTLELPDPAP
GDPPYVAVPYLSRMDLAYAAADLAICRSGAMTVAEVTAVGLPAVYVPLPIGNGEQRLNARPVVETGGGLVVDDADLSPQF
VADTVVPLLTDTGRLQTMTAGAALSGHRDAARHVAHVALDVAREAAGGRKGVR

Sequences:

>Translated_373_residues
MNGTISVLLAGGGTAGHVEPAMAVADALAALEPGVRITALGTERGLETRLVPERGYALELITPVPLPRKLSGDLARLPMR
VRRAVRETREILDTVHADVVIGFGGYVALPAYLAARRNRVPIVVHEANASAGLANKVGARFARRVLSAVADPGLGRVEVV
GTPVRSSITELDRAALRAEARAHFGFADDARVLLVFGGSQGARSLNNVVSGAAKALAAAGISVLHAYGAKNTLELPDPAP
GDPPYVAVPYLSRMDLAYAAADLAICRSGAMTVAEVTAVGLPAVYVPLPIGNGEQRLNARPVVETGGGLVVDDADLSPQF
VADTVVPLLTDTGRLQTMTAGAALSGHRDAARHVAHVALDVAREAAGGRKGVR
>Mature_373_residues
MNGTISVLLAGGGTAGHVEPAMAVADALAALEPGVRITALGTERGLETRLVPERGYALELITPVPLPRKLSGDLARLPMR
VRRAVRETREILDTVHADVVIGFGGYVALPAYLAARRNRVPIVVHEANASAGLANKVGARFARRVLSAVADPGLGRVEVV
GTPVRSSITELDRAALRAEARAHFGFADDARVLLVFGGSQGARSLNNVVSGAAKALAAAGISVLHAYGAKNTLELPDPAP
GDPPYVAVPYLSRMDLAYAAADLAICRSGAMTVAEVTAVGLPAVYVPLPIGNGEQRLNARPVVETGGGLVVDDADLSPQF
VADTVVPLLTDTGRLQTMTAGAALSGHRDAARHVAHVALDVAREAAGGRKGVR

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) [H]

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786278, Length=360, Percent_Identity=36.6666666666667, Blast_Score=182, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235 [H]

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28 [H]

EC number: =2.4.1.227 [H]

Molecular weight: Translated: 38518; Mature: 38518

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGTISVLLAGGGTAGHVEPAMAVADALAALEPGVRITALGTERGLETRLVPERGYALEL
CCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCEEECCCCCCEEEE
ITPVPLPRKLSGDLARLPMRVRRAVRETREILDTVHADVVIGFGGYVALPAYLAARRNRV
ECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCHHHHHHHHHHHHCCCC
PIVVHEANASAGLANKVGARFARRVLSAVADPGLGRVEVVGTPVRSSITELDRAALRAEA
CEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
RAHFGFADDARVLLVFGGSQGARSLNNVVSGAAKALAAAGISVLHAYGAKNTLELPDPAP
HHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
GDPPYVAVPYLSRMDLAYAAADLAICRSGAMTVAEVTAVGLPAVYVPLPIGNGEQRLNAR
CCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCEEEEEECCCCCHHHCCCC
PVVETGGGLVVDDADLSPQFVADTVVPLLTDTGRLQTMTAGAALSGHRDAARHVAHVALD
CEEECCCCEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHH
VAREAAGGRKGVR
HHHHHCCCCCCCC
>Mature Secondary Structure
MNGTISVLLAGGGTAGHVEPAMAVADALAALEPGVRITALGTERGLETRLVPERGYALEL
CCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCEEECCCCCCEEEE
ITPVPLPRKLSGDLARLPMRVRRAVRETREILDTVHADVVIGFGGYVALPAYLAARRNRV
ECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCHHHHHHHHHHHHCCCC
PIVVHEANASAGLANKVGARFARRVLSAVADPGLGRVEVVGTPVRSSITELDRAALRAEA
CEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
RAHFGFADDARVLLVFGGSQGARSLNNVVSGAAKALAAAGISVLHAYGAKNTLELPDPAP
HHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
GDPPYVAVPYLSRMDLAYAAADLAICRSGAMTVAEVTAVGLPAVYVPLPIGNGEQRLNAR
CCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCEEEEEECCCCCHHHCCCC
PVVETGGGLVVDDADLSPQFVADTVVPLLTDTGRLQTMTAGAALSGHRDAARHVAHVALD
CEEECCCCEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHH
VAREAAGGRKGVR
HHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA