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The map label for this gene is ftsW [C]

Identifier: 108800223

GI number: 108800223

Start: 3451728

End: 3453263

Strand: Reverse

Name: ftsW [C]

Synonym: Mmcs_3257

Alternate gene names: 108800223

Gene position: 3453263-3451728 (Counterclockwise)

Preceding gene: 108800224

Following gene: 108800222

Centisome position: 60.53

GC content: 70.9

Gene sequence:

>1536_bases
GTGGCGACGATCCTGGCCCGGTTGCGCGGTAAGGCGGCCGGCCCCGGCGCCGACGAACCGCCGAGGGCCGCCCAACCCCC
CACGGTGTCCCACACCCGCTTCGCGGCCTGGCTCGGCCGGCCGATGACGTCGTTCCACCTGATCATCGCCGTCACCGCCC
TGCTGATCACGCTCGGGCTGACCATGGTGCTCTCGGCATCCGGTGTGTACTCCTACGACTCCGACGGCTCACCCTGGTCG
GTGTTCGCCAAACAGGTGCTGTGGACGGTGGTCGGGCTCGTCGCGTTCTACGCGGCGCTGCGGATGCCGGTGAAGACGTT
GCGACGCTTGGCCTTCCCCGGCTTCGCGTTCACGATCGTGCTGCTGATCCTGGTGTTGATCCCGGGTATCGGCAAGGTCG
CCAACGGGTCGCGCGGCTGGTTCGTGGTGGCCGGGTTCTCCATGCAGCCCTCGGAGCTGGCGAAGATCGCGTTCGCGATC
TGGGGTGCGCACCTGCTGGCGGCGCGGCGCATGGAGCGGGCCACCCTGCGCGAGATGCTCGTCCCGTTGGTGCCAGCGGC
GGTCATCGCGCTGGCGTTGATCGTCGCCCAGCCCGACCTCGGCCAGACGGTGTCGCTGGGCATCATCCTGCTCGCCCTGC
TGTGGTATGCCGGCCTGCCGCTGAAGGTGTTCCTGTCCTCGCTGTTCGCGGTGATGGTGTCGGCGGCCGTGCTTGCCATG
GCGGAGGGCTACCGCTCAGCTCGCGTGCAGTCCTGGCTCGATCCCAGCGCCGATGCGCAGGGCTCGGGCTATCAGGCCCG
GCAGGCGAAGTTCGCGCTCGCCAACGGCGGCGTGTTCGGCGACGGGCTGGGGCAGGGCACCGCGAAGTGGAACTACCTGC
CCAACGCGCACAACGACTTCATCTTCGCGATCATCGGCGAGGAACTCGGATTCGTCGGCGCGGCCGGCCTGCTCGCCCTG
TTCGGGCTGTTCGCCTACACCGGAATGCGCATCGCGCGCCGCTCGGCCGATCCGTTCCTGCGACTGCTGACCGCCACCGC
GACGACATGGGTGCTCGGCCAGGTGTTCATCAACGTCGGCTACGTGGTGGGGTTGCTGCCCGTCACCGGACTGCAGCTGC
CGCTGATCTCCGCGGGCGGGACGTCGACCGCGACGACGCTGCTCATGATGGGCCTGATCACCAACGCCGCACGCCACGAA
CCCGATGCCGTGGCCGCGCTGCGGGCCGGCCGCGACGACCGGGTCAACCGGTTGCTGCGGCTGCCGCCGCCCGAGCCGTA
CGTGCCCACCCCGCTGGAGGCGGTGCGCGACCGGTTGCGCTCGCGGCCGGGCAAACCGGCCGCGCCACGGGCGGCCAAAC
CGGCGCGCGCGCCCCGGCGGCCCAAACCCCCCGCGGCTGAGGACCGGGTGCGGGGCTCAAGGCATCATGTAGGCGGTCAG
CGGTCGGCAACGCGCCGGACCGGTCAGGATCAACAGGGTCGGCGGGGCCAACAGGGCCGGCGAGCCCGCCCCAGGGAAGG
TCAACGTTACGGGTGA

Upstream 100 bases:

>100_bases
TGCTGGCGCCCGCAGGCGCCTCATTCGACCAGTTCAGCGGCTACACCCAGCGCGGCGACGCCTTCGCCGCCGCGGTGCGC
GCCGATCTCGGGTAGACGCC

Downstream 100 bases:

>100_bases
ACGGCACCATCTCGGTCCTCCTCGCCGGCGGCGGAACCGCGGGGCACGTCGAACCGGCGATGGCCGTCGCCGACGCGCTG
GCCGCGCTGGAGCCCGGGGT

Product: cell division protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 511; Mature: 510

Protein sequence:

>511_residues
MATILARLRGKAAGPGADEPPRAAQPPTVSHTRFAAWLGRPMTSFHLIIAVTALLITLGLTMVLSASGVYSYDSDGSPWS
VFAKQVLWTVVGLVAFYAALRMPVKTLRRLAFPGFAFTIVLLILVLIPGIGKVANGSRGWFVVAGFSMQPSELAKIAFAI
WGAHLLAARRMERATLREMLVPLVPAAVIALALIVAQPDLGQTVSLGIILLALLWYAGLPLKVFLSSLFAVMVSAAVLAM
AEGYRSARVQSWLDPSADAQGSGYQARQAKFALANGGVFGDGLGQGTAKWNYLPNAHNDFIFAIIGEELGFVGAAGLLAL
FGLFAYTGMRIARRSADPFLRLLTATATTWVLGQVFINVGYVVGLLPVTGLQLPLISAGGTSTATTLLMMGLITNAARHE
PDAVAALRAGRDDRVNRLLRLPPPEPYVPTPLEAVRDRLRSRPGKPAAPRAAKPARAPRRPKPPAAEDRVRGSRHHVGGQ
RSATRRTGQDQQGRRGQQGRRARPREGQRYG

Sequences:

>Translated_511_residues
MATILARLRGKAAGPGADEPPRAAQPPTVSHTRFAAWLGRPMTSFHLIIAVTALLITLGLTMVLSASGVYSYDSDGSPWS
VFAKQVLWTVVGLVAFYAALRMPVKTLRRLAFPGFAFTIVLLILVLIPGIGKVANGSRGWFVVAGFSMQPSELAKIAFAI
WGAHLLAARRMERATLREMLVPLVPAAVIALALIVAQPDLGQTVSLGIILLALLWYAGLPLKVFLSSLFAVMVSAAVLAM
AEGYRSARVQSWLDPSADAQGSGYQARQAKFALANGGVFGDGLGQGTAKWNYLPNAHNDFIFAIIGEELGFVGAAGLLAL
FGLFAYTGMRIARRSADPFLRLLTATATTWVLGQVFINVGYVVGLLPVTGLQLPLISAGGTSTATTLLMMGLITNAARHE
PDAVAALRAGRDDRVNRLLRLPPPEPYVPTPLEAVRDRLRSRPGKPAAPRAAKPARAPRRPKPPAAEDRVRGSRHHVGGQ
RSATRRTGQDQQGRRGQQGRRARPREGQRYG
>Mature_510_residues
ATILARLRGKAAGPGADEPPRAAQPPTVSHTRFAAWLGRPMTSFHLIIAVTALLITLGLTMVLSASGVYSYDSDGSPWSV
FAKQVLWTVVGLVAFYAALRMPVKTLRRLAFPGFAFTIVLLILVLIPGIGKVANGSRGWFVVAGFSMQPSELAKIAFAIW
GAHLLAARRMERATLREMLVPLVPAAVIALALIVAQPDLGQTVSLGIILLALLWYAGLPLKVFLSSLFAVMVSAAVLAMA
EGYRSARVQSWLDPSADAQGSGYQARQAKFALANGGVFGDGLGQGTAKWNYLPNAHNDFIFAIIGEELGFVGAAGLLALF
GLFAYTGMRIARRSADPFLRLLTATATTWVLGQVFINVGYVVGLLPVTGLQLPLISAGGTSTATTLLMMGLITNAARHEP
DAVAALRAGRDDRVNRLLRLPPPEPYVPTPLEAVRDRLRSRPGKPAAPRAAKPARAPRRPKPPAAEDRVRGSRHHVGGQR
SATRRTGQDQQGRRGQQGRRARPREGQRYG

Specific function: This Is A Septum-Peptidoglycan Biosynthetic Protein, Involved In Cell Wall Formation. Plays A Role In The Stabilization Of The Ftsz Ring During Cell Division. [C]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=363, Percent_Identity=33.8842975206612, Blast_Score=165, Evalue=6e-42,
Organism=Escherichia coli, GI1786853, Length=297, Percent_Identity=33.6700336700337, Blast_Score=127, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 54688; Mature: 54557

Theoretical pI: Translated: 11.88; Mature: 11.88

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ATILARLRGKAAGPGADEPPRAAQPPTVSHTRFAAWLGRPMTSFHLIIAVTALLITLGL
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
TMVLSASGVYSYDSDGSPWSVFAKQVLWTVVGLVAFYAALRMPVKTLRRLAFPGFAFTIV
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LLILVLIPGIGKVANGSRGWFVVAGFSMQPSELAKIAFAIWGAHLLAARRMERATLREML
HHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPLVPAAVIALALIVAQPDLGQTVSLGIILLALLWYAGLPLKVFLSSLFAVMVSAAVLAM
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
AEGYRSARVQSWLDPSADAQGSGYQARQAKFALANGGVFGDGLGQGTAKWNYLPNAHNDF
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHEEEECCCEECCCCCCCCCCCCCCCCCCCCE
IFAIIGEELGFVGAAGLLALFGLFAYTGMRIARRSADPFLRLLTATATTWVLGQVFINVG
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
YVVGLLPVTGLQLPLISAGGTSTATTLLMMGLITNAARHEPDAVAALRAGRDDRVNRLLR
HHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHEE
LPPPEPYVPTPLEAVRDRLRSRPGKPAAPRAAKPARAPRRPKPPAAEDRVRGSRHHVGGQ
CCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCHHCCCCC
RSATRRTGQDQQGRRGQQGRRARPREGQRYG
CHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]