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The map label for this gene is 108800181

Identifier: 108800181

GI number: 108800181

Start: 3406706

End: 3407872

Strand: Reverse

Name: 108800181

Synonym: Mmcs_3215

Alternate gene names: NA

Gene position: 3407872-3406706 (Counterclockwise)

Preceding gene: 108800182

Following gene: 108800180

Centisome position: 59.73

GC content: 67.18

Gene sequence:

>1167_bases
ATGCCACACGACCAGCCGGCCATCATCGGTGCCGCCGAACTCGCTCCAGGGAGAAACGTTCCGTACACCTCCACTGAATT
GCATGTGCGCGCCGCGGTCGCGGCTCTCGCCGACGCAGGGGTGGTCCCAGACGAGGTCGACGGTCTGGTGTGCGCCGGGC
CGATGACGAACGAGGGTTCGATCTTCCTGTCCGAGGACCTCATGGACTATCTCGGGCTGCACAATCTGAAACTTCAGATG
ACCTGTCAGCTTGGCGGCGGGACCCATCTCGCCATGACGCGCATGGCGAGTAACGTCATCGCCCGGGGCGAGGCCGAGAC
GGTGCTGGTCGTGTCGGCGGGCAAGTTTCCACCGATCCGCGATGGCGGGCGCGAACTGATGGCGCTGGTGTGTGACCACG
CGTTCGAGATGCCCTATGGACCGTCCGTGCCGGCGCTCTACGGTTTGATCGCGCAGGCCTGGATGCACGAGACGGGACAG
GGCAAGGCGGACATCGCCGAGGTCACCGTGTCGCAGGACCGTTGGGCCGCACTGAACCCCGCGGCTATCGCGCACGGCGC
TCAACGCCTGACTGTGGAGGACGTGCTGGCGTCCCGGCCGATCGCCGGGCCGTTCCACTTCTACCACTGCTCGATTCCCT
GCGAGGGCGGTGGCGCGCTGGTGCTGGGCTCGGCCCGCCGGGCTCGCGCGGGCAAGCACCGGCCGGTGCATTTGCTGGGC
TTTGGAGAGGGTCACACCCACGGTTTTCTGACCTCGCTGGCCCGGCCGGGTCGTACCGGGGCCGCCCGTTCGGGTCCGAT
GGCCTTTGAGCGCTCCGGACGGGCGCCGGCCGACGTCGACATCGCTTTGCTCTACGACGCCTTCGCCTCCAACCCGGCGA
TGATCCTTGAGGAGGCGGGTTTCGTGAAGCCCGGTGGGGCAGGCGATTTCTACCGTGACGGCTGCGCCGATCCGGGGGGC
GACCTTCCGGTGAACACCGACGGCGGCCTAATCCGGTTCGGGCACACCGGGACCTCCTCTGGCATTTCGCAGATCCTTGA
GGGTTACTGGCAGTTGTCCGGTCGCGCCGAGGGCCGTCAGGTGCCCGGGGCGGATACCGCGTTCGTGCACAGCTACGGCT
CGATGCTGTGCAGTCACGTCAGCATGGTGATGGAGGGAGCGTCATGA

Upstream 100 bases:

>100_bases
CGGCGGGTGCGGGCGGGGGTGACGCGGACCTCTAGGCACGCTATGCTAACCGTCGTTCACGTCGGGACCGGCGTTGGACG
CGTGGTCGAGAGGAGTCCGG

Downstream 100 bases:

>100_bases
CCGCAGCTTCGAGTTCTCTCGACGGTCTGCACGATCCTGAGGCGCTGCCGCCGCTGACCGATGTCAACCGTCCCTACTTC
GCAGCAGCGGCCCGCGGTGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MPHDQPAIIGAAELAPGRNVPYTSTELHVRAAVAALADAGVVPDEVDGLVCAGPMTNEGSIFLSEDLMDYLGLHNLKLQM
TCQLGGGTHLAMTRMASNVIARGEAETVLVVSAGKFPPIRDGGRELMALVCDHAFEMPYGPSVPALYGLIAQAWMHETGQ
GKADIAEVTVSQDRWAALNPAAIAHGAQRLTVEDVLASRPIAGPFHFYHCSIPCEGGGALVLGSARRARAGKHRPVHLLG
FGEGHTHGFLTSLARPGRTGAARSGPMAFERSGRAPADVDIALLYDAFASNPAMILEEAGFVKPGGAGDFYRDGCADPGG
DLPVNTDGGLIRFGHTGTSSGISQILEGYWQLSGRAEGRQVPGADTAFVHSYGSMLCSHVSMVMEGAS

Sequences:

>Translated_388_residues
MPHDQPAIIGAAELAPGRNVPYTSTELHVRAAVAALADAGVVPDEVDGLVCAGPMTNEGSIFLSEDLMDYLGLHNLKLQM
TCQLGGGTHLAMTRMASNVIARGEAETVLVVSAGKFPPIRDGGRELMALVCDHAFEMPYGPSVPALYGLIAQAWMHETGQ
GKADIAEVTVSQDRWAALNPAAIAHGAQRLTVEDVLASRPIAGPFHFYHCSIPCEGGGALVLGSARRARAGKHRPVHLLG
FGEGHTHGFLTSLARPGRTGAARSGPMAFERSGRAPADVDIALLYDAFASNPAMILEEAGFVKPGGAGDFYRDGCADPGG
DLPVNTDGGLIRFGHTGTSSGISQILEGYWQLSGRAEGRQVPGADTAFVHSYGSMLCSHVSMVMEGAS
>Mature_387_residues
PHDQPAIIGAAELAPGRNVPYTSTELHVRAAVAALADAGVVPDEVDGLVCAGPMTNEGSIFLSEDLMDYLGLHNLKLQMT
CQLGGGTHLAMTRMASNVIARGEAETVLVVSAGKFPPIRDGGRELMALVCDHAFEMPYGPSVPALYGLIAQAWMHETGQG
KADIAEVTVSQDRWAALNPAAIAHGAQRLTVEDVLASRPIAGPFHFYHCSIPCEGGGALVLGSARRARAGKHRPVHLLGF
GEGHTHGFLTSLARPGRTGAARSGPMAFERSGRAPADVDIALLYDAFASNPAMILEEAGFVKPGGAGDFYRDGCADPGGD
LPVNTDGGLIRFGHTGTSSGISQILEGYWQLSGRAEGRQVPGADTAFVHSYGSMLCSHVSMVMEGAS

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=384, Percent_Identity=24.4791666666667, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI302344767, Length=245, Percent_Identity=24.8979591836735, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI302344760, Length=245, Percent_Identity=24.8979591836735, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI302344762, Length=245, Percent_Identity=24.8979591836735, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI19921506, Length=379, Percent_Identity=25.5936675461741, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24585051, Length=382, Percent_Identity=25.6544502617801, Blast_Score=90, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: NA

Molecular weight: Translated: 40533; Mature: 40402

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHDQPAIIGAAELAPGRNVPYTSTELHVRAAVAALADAGVVPDEVDGLVCAGPMTNEGS
CCCCCCCEEEEHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCC
IFLSEDLMDYLGLHNLKLQMTCQLGGGTHLAMTRMASNVIARGEAETVLVVSAGKFPPIR
EEEHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCC
DGGRELMALVCDHAFEMPYGPSVPALYGLIAQAWMHETGQGKADIAEVTVSQDRWAALNP
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCC
AAIAHGAQRLTVEDVLASRPIAGPFHFYHCSIPCEGGGALVLGSARRARAGKHRPVHLLG
HHHHCCCHHCCHHHHHHCCCCCCCEEEEEEEEEECCCCEEEECCCHHHCCCCCCCEEEEE
FGEGHTHGFLTSLARPGRTGAARSGPMAFERSGRAPADVDIALLYDAFASNPAMILEEAG
CCCCCCHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCCCEEEEEEEHHHCCCCEEEECCCC
FVKPGGAGDFYRDGCADPGGDLPVNTDGGLIRFGHTGTSSGISQILEGYWQLSGRAEGRQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCC
VPGADTAFVHSYGSMLCSHVSMVMEGAS
CCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PHDQPAIIGAAELAPGRNVPYTSTELHVRAAVAALADAGVVPDEVDGLVCAGPMTNEGS
CCCCCCEEEEHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCC
IFLSEDLMDYLGLHNLKLQMTCQLGGGTHLAMTRMASNVIARGEAETVLVVSAGKFPPIR
EEEHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCC
DGGRELMALVCDHAFEMPYGPSVPALYGLIAQAWMHETGQGKADIAEVTVSQDRWAALNP
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCC
AAIAHGAQRLTVEDVLASRPIAGPFHFYHCSIPCEGGGALVLGSARRARAGKHRPVHLLG
HHHHCCCHHCCHHHHHHCCCCCCCEEEEEEEEEECCCCEEEECCCHHHCCCCCCCEEEEE
FGEGHTHGFLTSLARPGRTGAARSGPMAFERSGRAPADVDIALLYDAFASNPAMILEEAG
CCCCCCHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCCCEEEEEEEHHHCCCCEEEECCCC
FVKPGGAGDFYRDGCADPGGDLPVNTDGGLIRFGHTGTSSGISQILEGYWQLSGRAEGRQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCC
VPGADTAFVHSYGSMLCSHVSMVMEGAS
CCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]