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The map label for this gene is hisE

Identifier: 108800112

GI number: 108800112

Start: 3335808

End: 3336089

Strand: Reverse

Name: hisE

Synonym: Mmcs_3146

Alternate gene names: 108800112

Gene position: 3336089-3335808 (Counterclockwise)

Preceding gene: 108800113

Following gene: 108800111

Centisome position: 58.47

GC content: 67.73

Gene sequence:

>282_bases
GTGGGAGAATCGCAGCCCGTGAAGACCTTCGATGCGCTGTTCGACGAGTTGACCGAACGGGCGCGCACCCGGCCTGAGGG
CAGCGGCACCGTGGCGGCCCTCGACGGTGGCGTGCACGGCCTGGGCAAGAAGATCCTCGAGGAGGCCGGCGAGGTGTGGC
TGGCCGCCGAACACGAGAGCGACGAAGCGCTCGCCGAGGAGATCAGCCAGTTGCTGTACTGGACGCAGGTGCTGATGATC
GCCCGCGGCCTGTCACCCGACGACGTCTACCGCAAGCTGTGA

Upstream 100 bases:

>100_bases
TGTCCCTGGAGGACATGCACGGCGAGATCCTCAAGCACGACCTGCCCACGGGCGCCAAGGAGGGCTGAGGGCCGTGCCCG
CGTCGGGCTGACGGTGCGAC

Downstream 100 bases:

>100_bases
ACGGCATGCTGAGGGTCGCCGTGCCCAACAAGGGCACGCTGAGCGAACCGGCCGCCGAGATCCTGTCGGAGGCCGGCTAC
CGGCGCCGCACGGACACCAA

Product: phosphoribosyl-ATP pyrophosphatase

Products: NA

Alternate protein names: PRA-PH

Number of amino acids: Translated: 93; Mature: 92

Protein sequence:

>93_residues
MGESQPVKTFDALFDELTERARTRPEGSGTVAALDGGVHGLGKKILEEAGEVWLAAEHESDEALAEEISQLLYWTQVLMI
ARGLSPDDVYRKL

Sequences:

>Translated_93_residues
MGESQPVKTFDALFDELTERARTRPEGSGTVAALDGGVHGLGKKILEEAGEVWLAAEHESDEALAEEISQLLYWTQVLMI
ARGLSPDDVYRKL
>Mature_92_residues
GESQPVKTFDALFDELTERARTRPEGSGTVAALDGGVHGLGKKILEEAGEVWLAAEHESDEALAEEISQLLYWTQVLMIA
RGLSPDDVYRKL

Specific function: Unknown

COG id: COG0140

COG function: function code E; Phosphoribosyl-ATP pyrophosphohydrolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PRA-PH family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HIS2_MYCSJ (A3Q1B0)

Other databases:

- EMBL:   CP000580
- RefSeq:   YP_001071428.1
- ProteinModelPortal:   A3Q1B0
- SMR:   A3Q1B0
- STRING:   A3Q1B0
- EnsemblBacteria:   EBMYCT00000049482
- GeneID:   4878871
- GenomeReviews:   CP000580_GR
- KEGG:   mjl:Mjls_3158
- eggNOG:   COG0140
- GeneTree:   EBGT00050000017721
- HOGENOM:   HBG646527
- OMA:   VWMAAEY
- ProtClustDB:   PRK00400
- BioCyc:   MSP164757:MJLS_3158-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01020
- InterPro:   IPR008179
- InterPro:   IPR021130
- TIGRFAMs:   TIGR03188

Pfam domain/function: PF01503 PRA-PH

EC number: =3.6.1.31

Molecular weight: Translated: 10215; Mature: 10083

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGESQPVKTFDALFDELTERARTRPEGSGTVAALDGGVHGLGKKILEEAGEVWLAAEHES
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHEEEECCCCC
DEALAEEISQLLYWTQVLMIARGLSPDDVYRKL
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCC
>Mature Secondary Structure 
GESQPVKTFDALFDELTERARTRPEGSGTVAALDGGVHGLGKKILEEAGEVWLAAEHES
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHEEEECCCCC
DEALAEEISQLLYWTQVLMIARGLSPDDVYRKL
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA