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The map label for this gene is argK [C]

Identifier: 108800087

GI number: 108800087

Start: 3312394

End: 3313371

Strand: Reverse

Name: argK [C]

Synonym: Mmcs_3121

Alternate gene names: 108800087

Gene position: 3313371-3312394 (Counterclockwise)

Preceding gene: 108800088

Following gene: 108800086

Centisome position: 58.07

GC content: 70.25

Gene sequence:

>978_bases
ATGGCGGCCCCGACCGTCGCCGAGCTGTCCGCAGCGATCCGCAGCGGTGACCGGTCGGCGCTGGCGAAGGCGATCACCCT
GGTCGAGTCGACGCGCGCCGACCACCGCGAGCAGGCCCAGGAGCTGCTGCTGGAGCTGATGCCGCAGGCCGGCTCCGCCA
TGCACGTGGGCATCACCGGCGTGCCGGGGGTGGGGAAGTCGACGACCATCGAGGCGCTCGGCATGTACCTGATCGAGCAG
GGGCACCGGGTGGCCGTGCTGGCGGTGGATCCGTCCTCGACCCGCACCGGCGGCTCGATCCTCGGCGACAAGACCCGGAT
GGCGAAACTCGCCGTGCACCCCGATGCCTACATCCGTCCGTCGCCGACCTCCGGCACACTCGGCGGGGTCGCCAAGGCCA
CCCGCGAGACCATCGTGCTGCTCGAAGCCGCGGGCTACGACGTCATCCTGGTCGAGACCGTCGGGGTGGGGCAGTCCGAG
GTCACGGTGTCGAACATGGTCGACACGTTCGTGTTCCTCACCCTCGCCCGCACCGGTGACCAGCTGCAGGGCATCAAGAA
GGGCGTGCTCGAACTAGCCGACATCGTCGTCGTCAACAAGGCCGACGGCGAGCACGCCATCGAGGCGAAATCCGCCGCGC
GTGAGCTGACCGCCGCACTGCGGCTGATCTACCCGCGCGAGACGCTGTGGCGTCCGCCCGTGCTGACCATGAGCGCACTG
CACGGCGACGGGCTGCGCGAGCTGTGGGACAAGGTGCTCGAACACCGCGACGTGCTGCGCGAGGCCGGGCAGTTCGAGAA
CCGCCGACGCGCACAGCAGGTCGAGTGGACGTGGTCGATGGTGCGTGACGCGGTCCTCGACCGGGTACTGAACAATCCCG
AGGTGCGCCGGATCCGCGCCGAAGTGGAACGGCAGGTCCGCGACGGCGAGCTCACCCCGGCGCTGGCCGCGCGCCGGATT
CTCGACGCAGCGCACTGA

Upstream 100 bases:

>100_bases
GCCGCCGCCATCTTCCCGCCGGGCACCGTGATCGCCGACGCCGCGACCGGGCTGCTGCACAAACTCGCCGAACGGCTCGG
CTACGACCTGAACGCCTGAC

Downstream 100 bases:

>100_bases
AGCGGTGGCTGACCTGGTCGTTAACGCTTCAATAACGCTCTGTTTAAGTGCTGGTTCGGCGGGCTAGATTCATAGCTGTG
AGCAACCTCTCAGCGCGAGG

Product: arginine/ornithine transport system ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MAAPTVAELSAAIRSGDRSALAKAITLVESTRADHREQAQELLLELMPQAGSAMHVGITGVPGVGKSTTIEALGMYLIEQ
GHRVAVLAVDPSSTRTGGSILGDKTRMAKLAVHPDAYIRPSPTSGTLGGVAKATRETIVLLEAAGYDVILVETVGVGQSE
VTVSNMVDTFVFLTLARTGDQLQGIKKGVLELADIVVVNKADGEHAIEAKSAARELTAALRLIYPRETLWRPPVLTMSAL
HGDGLRELWDKVLEHRDVLREAGQFENRRRAQQVEWTWSMVRDAVLDRVLNNPEVRRIRAEVERQVRDGELTPALAARRI
LDAAH

Sequences:

>Translated_325_residues
MAAPTVAELSAAIRSGDRSALAKAITLVESTRADHREQAQELLLELMPQAGSAMHVGITGVPGVGKSTTIEALGMYLIEQ
GHRVAVLAVDPSSTRTGGSILGDKTRMAKLAVHPDAYIRPSPTSGTLGGVAKATRETIVLLEAAGYDVILVETVGVGQSE
VTVSNMVDTFVFLTLARTGDQLQGIKKGVLELADIVVVNKADGEHAIEAKSAARELTAALRLIYPRETLWRPPVLTMSAL
HGDGLRELWDKVLEHRDVLREAGQFENRRRAQQVEWTWSMVRDAVLDRVLNNPEVRRIRAEVERQVRDGELTPALAARRI
LDAAH
>Mature_324_residues
AAPTVAELSAAIRSGDRSALAKAITLVESTRADHREQAQELLLELMPQAGSAMHVGITGVPGVGKSTTIEALGMYLIEQG
HRVAVLAVDPSSTRTGGSILGDKTRMAKLAVHPDAYIRPSPTSGTLGGVAKATRETIVLLEAAGYDVILVETVGVGQSEV
TVSNMVDTFVFLTLARTGDQLQGIKKGVLELADIVVVNKADGEHAIEAKSAARELTAALRLIYPRETLWRPPVLTMSALH
GDGLRELWDKVLEHRDVLREAGQFENRRRAQQVEWTWSMVRDAVLDRVLNNPEVRRIRAEVERQVRDGELTPALAARRIL
DAAH

Specific function: Probable GTPase. May also bind and hydrolyze ATP. May function as chaperone (Probable) [H]

COG id: COG1703

COG function: function code E; Putative periplasmic protein kinase ArgK and related GTPases of G3E family

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgK family [H]

Homologues:

Organism=Homo sapiens, GI26892295, Length=328, Percent_Identity=46.6463414634146, Blast_Score=298, Evalue=4e-81,
Organism=Escherichia coli, GI1789285, Length=316, Percent_Identity=44.9367088607595, Blast_Score=276, Evalue=1e-75,
Organism=Caenorhabditis elegans, GI71994271, Length=329, Percent_Identity=42.2492401215805, Blast_Score=276, Evalue=1e-74,
Organism=Caenorhabditis elegans, GI71994275, Length=269, Percent_Identity=44.2379182156134, Blast_Score=253, Evalue=7e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005129 [H]

Pfam domain/function: PF03308 ArgK [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 35247; Mature: 35116

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAPTVAELSAAIRSGDRSALAKAITLVESTRADHREQAQELLLELMPQAGSAMHVGITG
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCEEEEEEEC
VPGVGKSTTIEALGMYLIEQGHRVAVLAVDPSSTRTGGSILGDKTRMAKLAVHPDAYIRP
CCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHEEEEECCCCCCCC
SPTSGTLGGVAKATRETIVLLEAAGYDVILVETVGVGQSEVTVSNMVDTFVFLTLARTGD
CCCCCCCHHHHHHHHHEEEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCH
QLQGIKKGVLELADIVVVNKADGEHAIEAKSAARELTAALRLIYPRETLWRPPVLTMSAL
HHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHH
HGDGLRELWDKVLEHRDVLREAGQFENRRRAQQVEWTWSMVRDAVLDRVLNNPEVRRIRA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
EVERQVRDGELTPALAARRILDAAH
HHHHHHHCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
AAPTVAELSAAIRSGDRSALAKAITLVESTRADHREQAQELLLELMPQAGSAMHVGITG
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCEEEEEEEC
VPGVGKSTTIEALGMYLIEQGHRVAVLAVDPSSTRTGGSILGDKTRMAKLAVHPDAYIRP
CCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHEEEEECCCCCCCC
SPTSGTLGGVAKATRETIVLLEAAGYDVILVETVGVGQSEVTVSNMVDTFVFLTLARTGD
CCCCCCCHHHHHHHHHEEEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCH
QLQGIKKGVLELADIVVVNKADGEHAIEAKSAARELTAALRLIYPRETLWRPPVLTMSAL
HHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHH
HGDGLRELWDKVLEHRDVLREAGQFENRRRAQQVEWTWSMVRDAVLDRVLNNPEVRRIRA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
EVERQVRDGELTPALAARRILDAAH
HHHHHHHCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Arg [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]