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The map label for this gene is nadA

Identifier: 108800034

GI number: 108800034

Start: 3243957

End: 3244970

Strand: Reverse

Name: nadA

Synonym: Mmcs_3068

Alternate gene names: 108800034

Gene position: 3244970-3243957 (Counterclockwise)

Preceding gene: 108800037

Following gene: 108800033

Centisome position: 56.87

GC content: 70.22

Gene sequence:

>1014_bases
GTGACGCTGCTTGACGAGACCGCTTCGGCGCAGTTCGGTGACGACGTCGCGCCCACCGAGGAGTGGGCCGCCGAAGTCCG
CCGCCTGGCCCGGCAGCGCGGGGCCACTCTGCTCGCGCACAACTACCAGCTGCCGGCGATCCAGGACGTCGCCGACCACG
TGGGCGATTCGCTGGCCCTGTCGCGGATCGCGGCCGAGGCGCCGGAGGACACCATCGTGTTCTGCGGTGTGCACTTCATG
GCCGAGACCGCCAAGATCCTCTCGCCGGACAAGACCGTGCTGATCCCCGACGCCAGGGCGGGCTGCTCGCTGGCCGATTC
GATCACCGCCGACCAGCTGCGGGAGTGGAAGGCCGAATACCCCGGCGCGGTGGTCGTGTCGTACGTCAACACCACCGCCG
CGGTGAAGGCCGAGACCGACATCTGCTGCACCTCGTCCAACGCCGTCGACGTCGTGGCGTCGATCCCCGCCGACCGTGAG
GTGCTGTTCTGCCCCGACCAGTTCCTCGGCGCCCATGTCCGCCGCGTCACCGGCCGGACGAACATGCAGATCTGGGCCGG
CGAGTGCCACGTACACGCCGGCATCAACGGTGACGAGCTCGCCGACCAGGCCCGCGCGCATCCGGATGCCGAACTGTTCG
TCCATCCTGAGTGCGGATGCGCCACCTCGGCGCTCTACCTCGCCGGCGAGGGCGCGTTCCCCGCCGACCGGGTGAAGATT
TTGTCGACGGGCGGCATGCTCGACGCGGCCCGCGAGAGCCGGGCCAGCCAGGTGCTGGTGGCCACCGAGGTCGGCATGCT
GCACCAACTGCGTCGTGCGGCCCCGGAGATCGACTTCCAGGCGGTCAACGACCGGGCCTCGTGCCGGTACATGAAGATGA
TCACGCCGGCCGCGCTGTTGCGCTGCCTGACCTACGGCACCGACGAGGTCGACGTCGACCACGAGACCGCCCGGCTGGCC
CGGCGCAGCGTGCAGCGGATGATCGAGATCGGGCAGCCCGGCGGCGGGGAATGA

Upstream 100 bases:

>100_bases
GCGAACCTGGAACACGACGGCGAGCACTTCGTGGGCGGTGCTAGTATGGGCCATGTTTTCGATTGTAAGTCGAAAACCGG
ATCGACACGAGGAGTCCACC

Downstream 100 bases:

>100_bases
CCGGCCCCGGGGGCAGAAGCGCAGCGACCGGGGGGAAGGCGGTTCGTCGCGGTTGCGGCGGCACCACACACTGGCAGCAG
CGTGCCGACGTCGTCGTGAT

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MTLLDETASAQFGDDVAPTEEWAAEVRRLARQRGATLLAHNYQLPAIQDVADHVGDSLALSRIAAEAPEDTIVFCGVHFM
AETAKILSPDKTVLIPDARAGCSLADSITADQLREWKAEYPGAVVVSYVNTTAAVKAETDICCTSSNAVDVVASIPADRE
VLFCPDQFLGAHVRRVTGRTNMQIWAGECHVHAGINGDELADQARAHPDAELFVHPECGCATSALYLAGEGAFPADRVKI
LSTGGMLDAARESRASQVLVATEVGMLHQLRRAAPEIDFQAVNDRASCRYMKMITPAALLRCLTYGTDEVDVDHETARLA
RRSVQRMIEIGQPGGGE

Sequences:

>Translated_337_residues
MTLLDETASAQFGDDVAPTEEWAAEVRRLARQRGATLLAHNYQLPAIQDVADHVGDSLALSRIAAEAPEDTIVFCGVHFM
AETAKILSPDKTVLIPDARAGCSLADSITADQLREWKAEYPGAVVVSYVNTTAAVKAETDICCTSSNAVDVVASIPADRE
VLFCPDQFLGAHVRRVTGRTNMQIWAGECHVHAGINGDELADQARAHPDAELFVHPECGCATSALYLAGEGAFPADRVKI
LSTGGMLDAARESRASQVLVATEVGMLHQLRRAAPEIDFQAVNDRASCRYMKMITPAALLRCLTYGTDEVDVDHETARLA
RRSVQRMIEIGQPGGGE
>Mature_336_residues
TLLDETASAQFGDDVAPTEEWAAEVRRLARQRGATLLAHNYQLPAIQDVADHVGDSLALSRIAAEAPEDTIVFCGVHFMA
ETAKILSPDKTVLIPDARAGCSLADSITADQLREWKAEYPGAVVVSYVNTTAAVKAETDICCTSSNAVDVVASIPADREV
LFCPDQFLGAHVRRVTGRTNMQIWAGECHVHAGINGDELADQARAHPDAELFVHPECGCATSALYLAGEGAFPADRVKIL
STGGMLDAARESRASQVLVATEVGMLHQLRRAAPEIDFQAVNDRASCRYMKMITPAALLRCLTYGTDEVDVDHETARLAR
RSVQRMIEIGQPGGGE

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily

Homologues:

Organism=Escherichia coli, GI1786964, Length=323, Percent_Identity=32.1981424148607, Blast_Score=152, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NADA_MYCSJ (A3Q137)

Other databases:

- EMBL:   CP000580
- RefSeq:   YP_001071355.1
- ProteinModelPortal:   A3Q137
- SMR:   A3Q137
- STRING:   A3Q137
- EnsemblBacteria:   EBMYCT00000047344
- GeneID:   4878798
- GenomeReviews:   CP000580_GR
- KEGG:   mjl:Mjls_3085
- eggNOG:   COG0379
- GeneTree:   EBGT00050000016402
- HOGENOM:   HBG291157
- OMA:   IAHPECE
- PhylomeDB:   A3Q137
- ProtClustDB:   PRK09375
- BioCyc:   MSP164757:MJLS_3085-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00568
- InterPro:   IPR003473
- InterPro:   IPR023066
- TIGRFAMs:   TIGR00550

Pfam domain/function: PF02445 NadA

EC number: =2.5.1.72

Molecular weight: Translated: 36256; Mature: 36125

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: BINDING 40-40 BINDING 57-57 BINDING 128-128 BINDING 145-145 BINDING 215-215 BINDING 243-243

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLLDETASAQFGDDVAPTEEWAAEVRRLARQRGATLLAHNYQLPAIQDVADHVGDSLAL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCHHHH
SRIAAEAPEDTIVFCGVHFMAETAKILSPDKTVLIPDARAGCSLADSITADQLREWKAEY
HHHHHCCCCCCEEEECHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHCCHHHHHHHHHHC
PGAVVVSYVNTTAAVKAETDICCTSSNAVDVVASIPADREVLFCPDQFLGAHVRRVTGRT
CCEEEEEEECCCEEEEECCCEEECCCCCEEEEEECCCCCEEEECCHHHHHHHHHHHCCCC
NMQIWAGECHVHAGINGDELADQARAHPDAELFVHPECGCATSALYLAGEGAFPADRVKI
CEEEEECCEEEECCCCHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEECCCCCCHHHEEE
LSTGGMLDAARESRASQVLVATEVGMLHQLRRAAPEIDFQAVNDRASCRYMKMITPAALL
EECCCCHHHHHHHHHCEEEEHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHCHHHHH
RCLTYGTDEVDVDHETARLARRSVQRMIEIGQPGGGE
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TLLDETASAQFGDDVAPTEEWAAEVRRLARQRGATLLAHNYQLPAIQDVADHVGDSLAL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCHHHH
SRIAAEAPEDTIVFCGVHFMAETAKILSPDKTVLIPDARAGCSLADSITADQLREWKAEY
HHHHHCCCCCCEEEECHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHCCHHHHHHHHHHC
PGAVVVSYVNTTAAVKAETDICCTSSNAVDVVASIPADREVLFCPDQFLGAHVRRVTGRT
CCEEEEEEECCCEEEEECCCEEECCCCCEEEEEECCCCCEEEECCHHHHHHHHHHHCCCC
NMQIWAGECHVHAGINGDELADQARAHPDAELFVHPECGCATSALYLAGEGAFPADRVKI
CEEEEECCEEEECCCCHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEECCCCCCHHHEEE
LSTGGMLDAARESRASQVLVATEVGMLHQLRRAAPEIDFQAVNDRASCRYMKMITPAALL
EECCCCHHHHHHHHHCEEEEHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHCHHHHH
RCLTYGTDEVDVDHETARLARRSVQRMIEIGQPGGGE
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA