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The map label for this gene is coaE [H]

Identifier: 108799970

GI number: 108799970

Start: 3174570

End: 3175727

Strand: Reverse

Name: coaE [H]

Synonym: Mmcs_3004

Alternate gene names: 108799970

Gene position: 3175727-3174570 (Counterclockwise)

Preceding gene: 108799971

Following gene: 108799967

Centisome position: 55.66

GC content: 69.43

Gene sequence:

>1158_bases
GTGCTGAGAATTGGATTGACCGGCGGCATCGGGGCGGGCAAGTCGACGGTGTCCGCGACATTCGCCGACTGCGGCGGGGT
CGTCGTCGACGGTGACGTGATCGCCCGCGAGGTCGTCGAACCGGGCACCGAGGGCCTCGCCGCACTCGTCGAGGCCTTCG
GTGATGACATCCTGCTTCCCGACGGTGCGCTGAACCGGCCCGCGTTGGCCGCCAAGGCATTTCAAGACGACGAACAACGC
GCCAAGTTGAACGGCATCGTGCACCCGCTGGTCGGCAAGCGCCGGCAGGAGATCATCGACTCGGTTGCCGAGGGCACCGT
CGTGGTCGAGGACATCCCGCTGTTGGTGGAAACCGGTATGGCACCCTTCTTCCCGCTCGTCGTGGTGGTGTGGGCCGACG
AAGAGACCCGGGTGACCCGTCTCATCGAACGCGGACTGCCCGAGCATGACGCCCGCGCGCGGATGAAGGCGCAGGCGGCC
GACGAGCAGCGGCGCGCCATCGCCGATGTGCTACTGGACAATTCGGGCACCCGGGAGGAACTCGTCGAGAAGGCGCGACA
ACTCTGGTTCGACCGGATTTTGCCCCTCGCCGAGAACATCCGCGCCGGTGAGGTGGTGCGCGTGGCGCCCCGGTTGGTGC
CGCACAACCCGGCGTGGGCCGCGGACGCACAGCGGATCGTCAACCGCATCAAGGCCGCCGCAGGGGGCAAGGCGCTGCGG
GTCGACCATGTCGGATCCACCTCGGTCGACGGCCTGGACGCCAAGGATGTCGTCGACATCCAGGTCACGGTGGCCTCGCT
CGAGGACGCCGACGAGATCGCCGGCGCGCTCGCGGCCGTGGGCTATCCCCGGGTGCCGGACGTCGACTCCGACGTGGCGC
ACGACGACTCCGGACGGTGGGGCAAACGCCTGCACGGCGCCGCCGATCCAGGCCGTCCCGCCAACATCCATCTGCGGGTC
GACGGCTGGCCGAACCAACGGTTCGCCCTGCTGTTCCCGGCGTGGTTGGCCGCCCACCCGGAGGTGCGCGATGAATACCT
GCAGGTCAAGCGCGCGGCGTTGAGCGCGCCGGACTACGCCGGGGCCAAGGAACCGTGGTTTGCCGAGGTGTACCCGAAGG
CGTCGGCGTGGGCCGAGGCCAGCGACTGGCGCCCCTGA

Upstream 100 bases:

>100_bases
GAGAAGCTGGCCGGTAACGCCTAGCAGTTGTCTCGACGAACGCCCCGGCTCACCGCGAGCCGGGGCGTTCGCCGTATCCG
GGTCCTGACAGACTGGTGCG

Downstream 100 bases:

>100_bases
GCCGTCAGACCCCCGGCGGAGCCGGTACAGCGTCCGCCGGTGGTGCGGCGGGATCCGCCGGAACCGGCGGTTGGGCGGGT
GCGGCCGCCGGGGTGGCGAC

Product: dephospho-CoA kinase/protein folding accessory domain-containing protein

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MLRIGLTGGIGAGKSTVSATFADCGGVVVDGDVIAREVVEPGTEGLAALVEAFGDDILLPDGALNRPALAAKAFQDDEQR
AKLNGIVHPLVGKRRQEIIDSVAEGTVVVEDIPLLVETGMAPFFPLVVVVWADEETRVTRLIERGLPEHDARARMKAQAA
DEQRRAIADVLLDNSGTREELVEKARQLWFDRILPLAENIRAGEVVRVAPRLVPHNPAWAADAQRIVNRIKAAAGGKALR
VDHVGSTSVDGLDAKDVVDIQVTVASLEDADEIAGALAAVGYPRVPDVDSDVAHDDSGRWGKRLHGAADPGRPANIHLRV
DGWPNQRFALLFPAWLAAHPEVRDEYLQVKRAALSAPDYAGAKEPWFAEVYPKASAWAEASDWRP

Sequences:

>Translated_385_residues
MLRIGLTGGIGAGKSTVSATFADCGGVVVDGDVIAREVVEPGTEGLAALVEAFGDDILLPDGALNRPALAAKAFQDDEQR
AKLNGIVHPLVGKRRQEIIDSVAEGTVVVEDIPLLVETGMAPFFPLVVVVWADEETRVTRLIERGLPEHDARARMKAQAA
DEQRRAIADVLLDNSGTREELVEKARQLWFDRILPLAENIRAGEVVRVAPRLVPHNPAWAADAQRIVNRIKAAAGGKALR
VDHVGSTSVDGLDAKDVVDIQVTVASLEDADEIAGALAAVGYPRVPDVDSDVAHDDSGRWGKRLHGAADPGRPANIHLRV
DGWPNQRFALLFPAWLAAHPEVRDEYLQVKRAALSAPDYAGAKEPWFAEVYPKASAWAEASDWRP
>Mature_385_residues
MLRIGLTGGIGAGKSTVSATFADCGGVVVDGDVIAREVVEPGTEGLAALVEAFGDDILLPDGALNRPALAAKAFQDDEQR
AKLNGIVHPLVGKRRQEIIDSVAEGTVVVEDIPLLVETGMAPFFPLVVVVWADEETRVTRLIERGLPEHDARARMKAQAA
DEQRRAIADVLLDNSGTREELVEKARQLWFDRILPLAENIRAGEVVRVAPRLVPHNPAWAADAQRIVNRIKAAAGGKALR
VDHVGSTSVDGLDAKDVVDIQVTVASLEDADEIAGALAAVGYPRVPDVDSDVAHDDSGRWGKRLHGAADPGRPANIHLRV
DGWPNQRFALLFPAWLAAHPEVRDEYLQVKRAALSAPDYAGAKEPWFAEVYPKASAWAEASDWRP

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=180, Percent_Identity=40, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI191252795, Length=180, Percent_Identity=40, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI110227607, Length=196, Percent_Identity=34.6938775510204, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI205277394, Length=199, Percent_Identity=35.678391959799, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI110227605, Length=199, Percent_Identity=35.678391959799, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI110227603, Length=199, Percent_Identity=35.678391959799, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI110227601, Length=199, Percent_Identity=35.678391959799, Blast_Score=90, Evalue=3e-18,
Organism=Escherichia coli, GI1786292, Length=174, Percent_Identity=39.6551724137931, Blast_Score=113, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17554944, Length=193, Percent_Identity=36.7875647668394, Blast_Score=122, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6320402, Length=192, Percent_Identity=40.1041666666667, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24644728, Length=231, Percent_Identity=34.1991341991342, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24658602, Length=193, Percent_Identity=34.1968911917098, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977
- InterPro:   IPR007344 [H]

Pfam domain/function: PF01121 CoaE; PF04229 UPF0157 [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 41483; Mature: 41483

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRIGLTGGIGAGKSTVSATFADCGGVVVDGDVIAREVVEPGTEGLAALVEAFGDDILLP
CEEEEECCCCCCCCHHHHHHHHCCCCEEECHHHHHHHHHCCCHHHHHHHHHHHCCCEECC
DGALNRPALAAKAFQDDEQRAKLNGIVHPLVGKRRQEIIDSVAEGTVVVEDIPLLVETGM
CCCCCCCHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHCCC
APFFPLVVVVWADEETRVTRLIERGLPEHDARARMKAQAADEQRRAIADVLLDNSGTREE
CCCCEEEEEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LVEKARQLWFDRILPLAENIRAGEVVRVAPRLVPHNPAWAADAQRIVNRIKAAAGGKALR
HHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHCCCCCCCHHHHHHHHHHHHHHCCCCEEE
VDHVGSTSVDGLDAKDVVDIQVTVASLEDADEIAGALAAVGYPRVPDVDSDVAHDDSGRW
EECCCCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCH
GKRLHGAADPGRPANIHLRVDGWPNQRFALLFPAWLAAHPEVRDEYLQVKRAALSAPDYA
HHHHCCCCCCCCCCEEEEEECCCCCCCEEEEEHHHHHCCCHHHHHHHHHHHHHHCCCCCC
GAKEPWFAEVYPKASAWAEASDWRP
CCCCCCCCEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MLRIGLTGGIGAGKSTVSATFADCGGVVVDGDVIAREVVEPGTEGLAALVEAFGDDILLP
CEEEEECCCCCCCCHHHHHHHHCCCCEEECHHHHHHHHHCCCHHHHHHHHHHHCCCEECC
DGALNRPALAAKAFQDDEQRAKLNGIVHPLVGKRRQEIIDSVAEGTVVVEDIPLLVETGM
CCCCCCCHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHCCC
APFFPLVVVVWADEETRVTRLIERGLPEHDARARMKAQAADEQRRAIADVLLDNSGTREE
CCCCEEEEEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LVEKARQLWFDRILPLAENIRAGEVVRVAPRLVPHNPAWAADAQRIVNRIKAAAGGKALR
HHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHCCCCCCCHHHHHHHHHHHHHHCCCCEEE
VDHVGSTSVDGLDAKDVVDIQVTVASLEDADEIAGALAAVGYPRVPDVDSDVAHDDSGRW
EECCCCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCH
GKRLHGAADPGRPANIHLRVDGWPNQRFALLFPAWLAAHPEVRDEYLQVKRAALSAPDYA
HHHHCCCCCCCCCCEEEEEECCCCCCCEEEEEHHHHHCCCHHHHHHHHHHHHHHCCCCCC
GAKEPWFAEVYPKASAWAEASDWRP
CCCCCCCCEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]