Click here to switch to the map view.

The map label for this gene is yebQ [C]

Identifier: 108799722

GI number: 108799722

Start: 2901569

End: 2903617

Strand: Reverse

Name: yebQ [C]

Synonym: Mmcs_2756

Alternate gene names: 108799722

Gene position: 2903617-2901569 (Counterclockwise)

Preceding gene: 108799723

Following gene: 108799721

Centisome position: 50.89

GC content: 68.77

Gene sequence:

>2049_bases
ATGGCGAGTTCACCCGCACCCACCGCAGCACCGCCGGAGGCCGGCAGCTCGTTGATCAGCCCGCAGCGGCGCAACCTGAT
CTTCGTCGCGGTGCTGCTCGGGATGCTGCTCGCCGCGCTCGACCAGACGATCGTCGCGACGGCGCTTCCGACCGTCGTGG
CCGATCTCGGCGGTGCCGGGCACCAGAGCTGGGTGGTGACGAGCTACCTGCTGGCCTCGACGATCGTCACCGCGATCGTC
GGCAAGCTCGGCGACATGTTCGGCCGCAAGACCGTCTTCCAGGCGGCGGTGGTGTTCTTCCTCGCCGGTTCGGTGCTGTG
CGGGCTCGCGGGTTCGATGGGCATGCTGGTGGCCGCACGCGCACTGCAGGGTGTCGGCGGCGGCGCGCTCATGGTGACGG
CCATGGCGCTCATCGGCGAGGTCATCCCGCTGCGGGACCGCGGCCGCTACCAGGGCGCGCTGGGCGCCGTCTTCGGTGTC
ACCACCGTCATCGGCCCGCTGCTGGGCGGCTTCTTCACCGACCACCTGAGCTGGCGCTGGGCGTTCTGGATCAACGTGCC
GGTGGGCATCGTGGTGTTCTTCGTGGCCGCCGCCGCGATCCCCGCGCTGAGCCGGGTCGGCCGGGCCAAGATCGACTACG
CAGGCATCGTCTTCGTCGGCCTCGGCGCCTCCGGCCTGACATTGGCGACGAGCTGGGGCGGGGCCGAGTACGCCTGGACG
TCGCCGGTCATCATCGGCCTGTTCGTCGCCTCCGCGCTGGCGCTGGCGGTGTTCATCCAGGTCGAGCGACGCGCTGCCGA
ACCGATCCTGCCGATGCGGTTGTTCGCCAGCCCCGTGTTCACGGTCTGCTGCATCCTGTCGTTCATCGTCGGCTTCGCGA
TGCTCGGGGCGCTGACCTTCCTGCCCACCTTCATGCAATTCGTCGACGGCGTCTCGGCCACCGAATCGGGGTTGCGCACA
CTGCCGATGGTGGCGGGTCTGCTCATCACCTCGACGGGCAGCGGGGCCATCGTCGGCCGCACCGGGCGGTACAAGATCTT
CCCCGTCCTGGGCACCGCGATCATGACGGTCGCCTTCGTCCTGCTGTCCCGGATGGACGCCACGACGCACCTGCTGCAGC
AGTCGCTGTACCTCTTCATCCTCGGCACCGGAATCGGGTTGTGCATGCAGGTGCTCGTGCTCACCGTGCAGAACACCGCC
ACCTTCGAAGACCTCGGTGTCGCCACCTCAGGTGTGACGTTCTTCCGCACCATCGGCAGCTCGTTCGGTGCGGCCATCTT
CGGGTCGCTGTTCGCCAACTTCCTCGACGACCGGATCGGCGCGGCACTGCTGAGCAGCGGCGCGCCCCCGGTCGCGGCCG
AGTCCCCCCAGGCGCTGCATCGCCTGGCACCCGATGTCGCTGCACCGATCGTCGACGCCTACGCCGATTCGCTCGGTCTG
GTGTTCTTGTGCGCCGCCCCGATCGCGGCCGTCGGATTCCTGGTGGCGCTGCTGCTCAAAGAGGTGCCGCTGCGGGAGAT
GGAGACCGGCGCCGCCGTGGATCTCGGCGAGGGGTTCGCGATGCCGGGTGCCGAATCCTCCGAGCAGATGCTCGAATCCG
CGGTGGGCCGGATGCTGCGCCACTCGCCCGACATCCGGTTGCGGTCGGTGGCCGGGCGGCCGGGCTGCGAACTCGACGTC
GCGCGGCTGTGGGCGCTGCTGCAGATCTACCGCCACAACCAGGTTTTCGGTTCTGCCCGGTTGAGCGAGATCGCCGACCG
GCTGCGCATCCCGTGTGAGGTGGTCGAACCGGTCTTCGACGATCTGGTGGCCGGCGGGTACGCCGTGCGGACCGGGGATC
TGCTGTGGCTGAGTCAATCCGGAGTCCGCCAGGTCGATGCCGTGTCGTCGGCGTTCGTCGGCATGATCGTCGACAAGCTC
GCGCAGTCACCCACATTCGAGGGACGGCCCGACCGGTTGCAGGTGGAGGCGGCGCTGGAACGGATCACCCACCGCATGCT
CGTACAGCGCGACTGGGATTGGGACGACGAACTCGAACGCGCTCAGTGA

Upstream 100 bases:

>100_bases
GGTCGTTTCGTGTCCGGAGGTCCTCCGGAATCAAAACGGGTCGCCGTAACTTTTATAGCCAGGCTAACGATGTAGGTTTC
GGCATCGACGGAAGGTACGC

Downstream 100 bases:

>100_bases
TCCCGGCCTGCGCGTAGCATGCGGCCATGAGCCGAATCGGAGACGCCGCCCGGGACTTCGCCGACGATGACGTGACGGCC
TTCGCGGTTCGTTCACCCGA

Product: EmrB/QacA family drug resistance transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 682; Mature: 681

Protein sequence:

>682_residues
MASSPAPTAAPPEAGSSLISPQRRNLIFVAVLLGMLLAALDQTIVATALPTVVADLGGAGHQSWVVTSYLLASTIVTAIV
GKLGDMFGRKTVFQAAVVFFLAGSVLCGLAGSMGMLVAARALQGVGGGALMVTAMALIGEVIPLRDRGRYQGALGAVFGV
TTVIGPLLGGFFTDHLSWRWAFWINVPVGIVVFFVAAAAIPALSRVGRAKIDYAGIVFVGLGASGLTLATSWGGAEYAWT
SPVIIGLFVASALALAVFIQVERRAAEPILPMRLFASPVFTVCCILSFIVGFAMLGALTFLPTFMQFVDGVSATESGLRT
LPMVAGLLITSTGSGAIVGRTGRYKIFPVLGTAIMTVAFVLLSRMDATTHLLQQSLYLFILGTGIGLCMQVLVLTVQNTA
TFEDLGVATSGVTFFRTIGSSFGAAIFGSLFANFLDDRIGAALLSSGAPPVAAESPQALHRLAPDVAAPIVDAYADSLGL
VFLCAAPIAAVGFLVALLLKEVPLREMETGAAVDLGEGFAMPGAESSEQMLESAVGRMLRHSPDIRLRSVAGRPGCELDV
ARLWALLQIYRHNQVFGSARLSEIADRLRIPCEVVEPVFDDLVAGGYAVRTGDLLWLSQSGVRQVDAVSSAFVGMIVDKL
AQSPTFEGRPDRLQVEAALERITHRMLVQRDWDWDDELERAQ

Sequences:

>Translated_682_residues
MASSPAPTAAPPEAGSSLISPQRRNLIFVAVLLGMLLAALDQTIVATALPTVVADLGGAGHQSWVVTSYLLASTIVTAIV
GKLGDMFGRKTVFQAAVVFFLAGSVLCGLAGSMGMLVAARALQGVGGGALMVTAMALIGEVIPLRDRGRYQGALGAVFGV
TTVIGPLLGGFFTDHLSWRWAFWINVPVGIVVFFVAAAAIPALSRVGRAKIDYAGIVFVGLGASGLTLATSWGGAEYAWT
SPVIIGLFVASALALAVFIQVERRAAEPILPMRLFASPVFTVCCILSFIVGFAMLGALTFLPTFMQFVDGVSATESGLRT
LPMVAGLLITSTGSGAIVGRTGRYKIFPVLGTAIMTVAFVLLSRMDATTHLLQQSLYLFILGTGIGLCMQVLVLTVQNTA
TFEDLGVATSGVTFFRTIGSSFGAAIFGSLFANFLDDRIGAALLSSGAPPVAAESPQALHRLAPDVAAPIVDAYADSLGL
VFLCAAPIAAVGFLVALLLKEVPLREMETGAAVDLGEGFAMPGAESSEQMLESAVGRMLRHSPDIRLRSVAGRPGCELDV
ARLWALLQIYRHNQVFGSARLSEIADRLRIPCEVVEPVFDDLVAGGYAVRTGDLLWLSQSGVRQVDAVSSAFVGMIVDKL
AQSPTFEGRPDRLQVEAALERITHRMLVQRDWDWDDELERAQ
>Mature_681_residues
ASSPAPTAAPPEAGSSLISPQRRNLIFVAVLLGMLLAALDQTIVATALPTVVADLGGAGHQSWVVTSYLLASTIVTAIVG
KLGDMFGRKTVFQAAVVFFLAGSVLCGLAGSMGMLVAARALQGVGGGALMVTAMALIGEVIPLRDRGRYQGALGAVFGVT
TVIGPLLGGFFTDHLSWRWAFWINVPVGIVVFFVAAAAIPALSRVGRAKIDYAGIVFVGLGASGLTLATSWGGAEYAWTS
PVIIGLFVASALALAVFIQVERRAAEPILPMRLFASPVFTVCCILSFIVGFAMLGALTFLPTFMQFVDGVSATESGLRTL
PMVAGLLITSTGSGAIVGRTGRYKIFPVLGTAIMTVAFVLLSRMDATTHLLQQSLYLFILGTGIGLCMQVLVLTVQNTAT
FEDLGVATSGVTFFRTIGSSFGAAIFGSLFANFLDDRIGAALLSSGAPPVAAESPQALHRLAPDVAAPIVDAYADSLGLV
FLCAAPIAAVGFLVALLLKEVPLREMETGAAVDLGEGFAMPGAESSEQMLESAVGRMLRHSPDIRLRSVAGRPGCELDVA
RLWALLQIYRHNQVFGSARLSEIADRLRIPCEVVEPVFDDLVAGGYAVRTGDLLWLSQSGVRQVDAVSSAFVGMIVDKLA
QSPTFEGRPDRLQVEAALERITHRMLVQRDWDWDDELERAQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=419, Percent_Identity=30.3102625298329, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1789042, Length=439, Percent_Identity=27.3348519362187, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI1788710, Length=319, Percent_Identity=29.153605015674, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI1788392, Length=339, Percent_Identity=31.5634218289086, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1790195, Length=386, Percent_Identity=28.4974093264249, Blast_Score=109, Evalue=6e-25,
Organism=Escherichia coli, GI1790146, Length=174, Percent_Identity=29.8850574712644, Blast_Score=70, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6322958, Length=524, Percent_Identity=25.1908396946565, Blast_Score=148, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6319770, Length=385, Percent_Identity=29.6103896103896, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6323735, Length=307, Percent_Identity=30.2931596091205, Blast_Score=121, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6325455, Length=513, Percent_Identity=22.4171539961014, Blast_Score=110, Evalue=9e-25,
Organism=Saccharomyces cerevisiae, GI6319783, Length=437, Percent_Identity=24.4851258581236, Blast_Score=108, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6321663, Length=378, Percent_Identity=24.6031746031746, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6324954, Length=394, Percent_Identity=25.6345177664975, Blast_Score=90, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6323520, Length=301, Percent_Identity=26.578073089701, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829
- InterPro:   IPR001958
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 71823; Mature: 71692

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASSPAPTAAPPEAGSSLISPQRRNLIFVAVLLGMLLAALDQTIVATALPTVVADLGGAG
CCCCCCCCCCCCCCCCHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
HQSWVVTSYLLASTIVTAIVGKLGDMFGRKTVFQAAVVFFLAGSVLCGLAGSMGMLVAAR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALQGVGGGALMVTAMALIGEVIPLRDRGRYQGALGAVFGVTTVIGPLLGGFFTDHLSWRW
HHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
AFWINVPVGIVVFFVAAAAIPALSRVGRAKIDYAGIVFVGLGASGLTLATSWGGAEYAWT
EEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCEEEECCCCCCCCCC
SPVIIGLFVASALALAVFIQVERRAAEPILPMRLFASPVFTVCCILSFIVGFAMLGALTF
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPTFMQFVDGVSATESGLRTLPMVAGLLITSTGSGAIVGRTGRYKIFPVLGTAIMTVAFV
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEHHHHHHHHHHHHHH
LLSRMDATTHLLQQSLYLFILGTGIGLCMQVLVLTVQNTATFEDLGVATSGVTFFRTIGS
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHCCHHHHHHHHH
SFGAAIFGSLFANFLDDRIGAALLSSGAPPVAAESPQALHRLAPDVAAPIVDAYADSLGL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHH
VFLCAAPIAAVGFLVALLLKEVPLREMETGAAVDLGEGFAMPGAESSEQMLESAVGRMLR
HHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHH
HSPDIRLRSVAGRPGCELDVARLWALLQIYRHNQVFGSARLSEIADRLRIPCEVVEPVFD
CCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
DLVAGGYAVRTGDLLWLSQSGVRQVDAVSSAFVGMIVDKLAQSPTFEGRPDRLQVEAALE
HHHCCCEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
RITHRMLVQRDWDWDDELERAQ
HHHHHHHHHCCCCCCHHHHCCC
>Mature Secondary Structure 
ASSPAPTAAPPEAGSSLISPQRRNLIFVAVLLGMLLAALDQTIVATALPTVVADLGGAG
CCCCCCCCCCCCCCCHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
HQSWVVTSYLLASTIVTAIVGKLGDMFGRKTVFQAAVVFFLAGSVLCGLAGSMGMLVAAR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALQGVGGGALMVTAMALIGEVIPLRDRGRYQGALGAVFGVTTVIGPLLGGFFTDHLSWRW
HHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
AFWINVPVGIVVFFVAAAAIPALSRVGRAKIDYAGIVFVGLGASGLTLATSWGGAEYAWT
EEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCEEEECCCCCCCCCC
SPVIIGLFVASALALAVFIQVERRAAEPILPMRLFASPVFTVCCILSFIVGFAMLGALTF
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPTFMQFVDGVSATESGLRTLPMVAGLLITSTGSGAIVGRTGRYKIFPVLGTAIMTVAFV
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEHHHHHHHHHHHHHH
LLSRMDATTHLLQQSLYLFILGTGIGLCMQVLVLTVQNTATFEDLGVATSGVTFFRTIGS
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHCCHHHHHHHHH
SFGAAIFGSLFANFLDDRIGAALLSSGAPPVAAESPQALHRLAPDVAAPIVDAYADSLGL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHH
VFLCAAPIAAVGFLVALLLKEVPLREMETGAAVDLGEGFAMPGAESSEQMLESAVGRMLR
HHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHH
HSPDIRLRSVAGRPGCELDVARLWALLQIYRHNQVFGSARLSEIADRLRIPCEVVEPVFD
CCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
DLVAGGYAVRTGDLLWLSQSGVRQVDAVSSAFVGMIVDKLAQSPTFEGRPDRLQVEAALE
HHHCCCEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
RITHRMLVQRDWDWDDELERAQ
HHHHHHHHHCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]