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The map label for this gene is lat [H]

Identifier: 108798243

GI number: 108798243

Start: 1381334

End: 1382656

Strand: Direct

Name: lat [H]

Synonym: Mmcs_1272

Alternate gene names: 108798243

Gene position: 1381334-1382656 (Clockwise)

Preceding gene: 108798242

Following gene: 108798245

Centisome position: 24.21

GC content: 67.95

Gene sequence:

>1323_bases
ATGACCGACATGTTGACGCGTGCCGAAACCGTGGTCACACCCGCCCGGGTCCACGACGTCCTGGCCCGCAGCATCCTCGC
CGACGGTTTCGATCTCGTGCTCGACCTCGAGCGGTCGGCGGGCTCGTATCTGGTCGACGCCCGCACCGGTGAGCGCTACC
TCGACATGTTCACCTTCTTCGCGTCATCCTCCCTGGGCATGAATCATCCGGCCCTCGCGGCGGACGACGAGTTCCGTGCC
GAACTCACCCAGGCCGCCGTCAACAAGCCGAGCAACTCCGACGTCTACTCCGTGCCGATGGCCCGGTTCGTCGACACGTT
CGCACGGGTGCTGGGTGACCCGGCACTGCCGCACCTGTTCTTCGTCGACGGTGGTGCACTGGCTGTGGAGAACGCGCTCA
AGGTCGCCTTCGACTGGAAGAGCCGTCTCAACGAATCCCGCGGTCTCGACCCGGCCCTGGGCACGCGCGTGCTGCACCTT
CGTGGGGCGTTCCACGGTCGCAGCGGATACACGCTGTCGCTGACGAACACCGACCCGAACAAGGTGGCGCGGTTCCCGAA
ATTCGACTGGCCGCGGATCGACGCGCCGTTCATCCGTCCGGGAGCCGATATGGCCGCCCTCGAGGCGGAGTCGGTGCGCC
AGGCCCGCGCCGCATTCGAGGCGTATCCGCATGACATCGCCTGTTTCATCGCCGAGCCGATCCAGGGTGAAGGAGGCGAC
CGGCACTTCCGGCCGGAGTTCTTCGTCGCGATGCGGGCGCTGTGCGACGAGTTCGATGCGCTGCTGATCGTCGACGAGGT
ACAGACCGGCTGCGGGATCACCGGAACGCCATGGGCGTACCAGCAATTGGGCATCACCCCCGACGTGGTGGCGTTCGGCA
AGAAGACCCAGGTGTGCGGGGTGATGGCCGGACGGCGCGTCGACGAGGTCACCGACAACGTCTTCGCGGTGAGCTCACGC
ATCAATTCGACCTGGGGCGGCAATCTCACCGACATGGTGCGCGCCCGGCGCATCCTCGAGGTGATCGAGGCCGACGATCT
GCCGGCGTGCGCCGCCCGCGCAGGCGACTACCTGCAGGCCCGGCTCGAAGAGCTCGCCGACGAGTTCCCCGGCGTGGTGC
TCGACGTGCGGGGCCGCGGACTCATGCGCGCGTTCAGCCTGCCGTCGCAGGCGCAACGCGACGATCTGATCCGCCGGTTG
TGGGAGCGGCGGGTGATCATGTTGGCGAGCGGGGTGGATTCGGTGCGCTTCCGCCCGGCGCTGACGGTGTCCCGGGCGGA
ACTCGACGCCGCGGTGGATGCGGTGCGCGAGGCCTTGCGCTGA

Upstream 100 bases:

>100_bases
GGAGGTGCCGGACAGTAGCCGCTCCGCGCGCTCAGGCCAGGACCGGAATTGATGGTTTCCAGAGTGCGATGGACAGGAAA
ATATCCGGTAGACTGACCGT

Downstream 100 bases:

>100_bases
CATCGGCGTCCTCGGTGAGGCGCCGGATGGTCGAGCGGAGCCGAGGGAGTTCCTGACGGCCGACCAGTTCGCACCCGTGG
CGTTCGGCGAGTTTGCGTGC

Product: L-lysine aminotransferase

Products: NA

Alternate protein names: L-lysine aminotransferase; Lysine 6-aminotransferase [H]

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MTDMLTRAETVVTPARVHDVLARSILADGFDLVLDLERSAGSYLVDARTGERYLDMFTFFASSSLGMNHPALAADDEFRA
ELTQAAVNKPSNSDVYSVPMARFVDTFARVLGDPALPHLFFVDGGALAVENALKVAFDWKSRLNESRGLDPALGTRVLHL
RGAFHGRSGYTLSLTNTDPNKVARFPKFDWPRIDAPFIRPGADMAALEAESVRQARAAFEAYPHDIACFIAEPIQGEGGD
RHFRPEFFVAMRALCDEFDALLIVDEVQTGCGITGTPWAYQQLGITPDVVAFGKKTQVCGVMAGRRVDEVTDNVFAVSSR
INSTWGGNLTDMVRARRILEVIEADDLPACAARAGDYLQARLEELADEFPGVVLDVRGRGLMRAFSLPSQAQRDDLIRRL
WERRVIMLASGVDSVRFRPALTVSRAELDAAVDAVREALR

Sequences:

>Translated_440_residues
MTDMLTRAETVVTPARVHDVLARSILADGFDLVLDLERSAGSYLVDARTGERYLDMFTFFASSSLGMNHPALAADDEFRA
ELTQAAVNKPSNSDVYSVPMARFVDTFARVLGDPALPHLFFVDGGALAVENALKVAFDWKSRLNESRGLDPALGTRVLHL
RGAFHGRSGYTLSLTNTDPNKVARFPKFDWPRIDAPFIRPGADMAALEAESVRQARAAFEAYPHDIACFIAEPIQGEGGD
RHFRPEFFVAMRALCDEFDALLIVDEVQTGCGITGTPWAYQQLGITPDVVAFGKKTQVCGVMAGRRVDEVTDNVFAVSSR
INSTWGGNLTDMVRARRILEVIEADDLPACAARAGDYLQARLEELADEFPGVVLDVRGRGLMRAFSLPSQAQRDDLIRRL
WERRVIMLASGVDSVRFRPALTVSRAELDAAVDAVREALR
>Mature_439_residues
TDMLTRAETVVTPARVHDVLARSILADGFDLVLDLERSAGSYLVDARTGERYLDMFTFFASSSLGMNHPALAADDEFRAE
LTQAAVNKPSNSDVYSVPMARFVDTFARVLGDPALPHLFFVDGGALAVENALKVAFDWKSRLNESRGLDPALGTRVLHLR
GAFHGRSGYTLSLTNTDPNKVARFPKFDWPRIDAPFIRPGADMAALEAESVRQARAAFEAYPHDIACFIAEPIQGEGGDR
HFRPEFFVAMRALCDEFDALLIVDEVQTGCGITGTPWAYQQLGITPDVVAFGKKTQVCGVMAGRRVDEVTDNVFAVSSRI
NSTWGGNLTDMVRARRILEVIEADDLPACAARAGDYLQARLEELADEFPGVVLDVRGRGLMRAFSLPSQAQRDDLIRRLW
ERRVIMLASGVDSVRFRPALTVSRAELDAAVDAVREALR

Specific function: Unknown

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI188536080, Length=423, Percent_Identity=30.2600472813239, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI38679950, Length=423, Percent_Identity=30.2600472813239, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI38679946, Length=423, Percent_Identity=30.2600472813239, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI13994255, Length=459, Percent_Identity=25.9259259259259, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI4557809, Length=438, Percent_Identity=26.2557077625571, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI284507298, Length=321, Percent_Identity=28.9719626168224, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI37574042, Length=431, Percent_Identity=24.3619489559165, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI226442705, Length=431, Percent_Identity=23.6658932714617, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI226442709, Length=345, Percent_Identity=24.9275362318841, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI145693181, Length=422, Percent_Identity=28.1990521327014, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1789016, Length=413, Percent_Identity=29.2978208232446, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1788044, Length=402, Percent_Identity=29.1044776119403, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1789759, Length=404, Percent_Identity=27.970297029703, Blast_Score=121, Evalue=8e-29,
Organism=Escherichia coli, GI1787560, Length=409, Percent_Identity=26.8948655256724, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786349, Length=287, Percent_Identity=29.9651567944251, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1786991, Length=343, Percent_Identity=26.530612244898, Blast_Score=93, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17541228, Length=438, Percent_Identity=32.4200913242009, Blast_Score=184, Evalue=8e-47,
Organism=Caenorhabditis elegans, GI25144271, Length=410, Percent_Identity=25.3658536585366, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI25144274, Length=284, Percent_Identity=28.169014084507, Blast_Score=99, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI32564660, Length=445, Percent_Identity=24.4943820224719, Blast_Score=96, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6321456, Length=435, Percent_Identity=29.4252873563218, Blast_Score=149, Evalue=9e-37,
Organism=Saccharomyces cerevisiae, GI6324432, Length=418, Percent_Identity=26.3157894736842, Blast_Score=124, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6323470, Length=417, Percent_Identity=28.2973621103118, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6324386, Length=255, Percent_Identity=29.0196078431373, Blast_Score=88, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281366494, Length=434, Percent_Identity=30.4147465437788, Blast_Score=167, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24667139, Length=434, Percent_Identity=30.4147465437788, Blast_Score=167, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24667143, Length=434, Percent_Identity=30.4147465437788, Blast_Score=167, Evalue=2e-41,
Organism=Drosophila melanogaster, GI21357415, Length=411, Percent_Identity=26.7639902676399, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI21356575, Length=430, Percent_Identity=26.046511627907, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI28574759, Length=478, Percent_Identity=25.3138075313808, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI161085790, Length=479, Percent_Identity=25.0521920668058, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR017657
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.36 [H]

Molecular weight: Translated: 48427; Mature: 48295

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDMLTRAETVVTPARVHDVLARSILADGFDLVLDLERSAGSYLVDARTGERYLDMFTFF
CCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCHHHHHHHHHH
ASSSLGMNHPALAADDEFRAELTQAAVNKPSNSDVYSVPMARFVDTFARVLGDPALPHLF
HCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEECHHHHHHHHHHHHHCCCCCCEEE
FVDGGALAVENALKVAFDWKSRLNESRGLDPALGTRVLHLRGAFHGRSGYTLSLTNTDPN
EECCCHHHHHHHHHHEECHHHHCCHHCCCCHHHHHEEEEEECCCCCCCCCEEEEECCCHH
KVARFPKFDWPRIDAPFIRPGADMAALEAESVRQARAAFEAYPHDIACFIAEPIQGEGGD
HHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCC
RHFRPEFFVAMRALCDEFDALLIVDEVQTGCGITGTPWAYQQLGITPDVVAFGKKTQVCG
CCCCHHHHHHHHHHHHCCCEEEEEEEHHCCCCCCCCCCHHHHCCCCHHHHHCCCCCHHHH
VMAGRRVDEVTDNVFAVSSRINSTWGGNLTDMVRARRILEVIEADDLPACAARAGDYLQA
HHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
RLEELADEFPGVVLDVRGRGLMRAFSLPSQAQRDDLIRRLWERRVIMLASGVDSVRFRPA
HHHHHHHHCCCEEEEECCCCHHHHHCCCCCCHHHHHHHHHHHCCEEEEECCCCCCEECCC
LTVSRAELDAAVDAVREALR
EEHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
TDMLTRAETVVTPARVHDVLARSILADGFDLVLDLERSAGSYLVDARTGERYLDMFTFF
CCHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCHHHHHHHHHH
ASSSLGMNHPALAADDEFRAELTQAAVNKPSNSDVYSVPMARFVDTFARVLGDPALPHLF
HCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEECHHHHHHHHHHHHHCCCCCCEEE
FVDGGALAVENALKVAFDWKSRLNESRGLDPALGTRVLHLRGAFHGRSGYTLSLTNTDPN
EECCCHHHHHHHHHHEECHHHHCCHHCCCCHHHHHEEEEEECCCCCCCCCEEEEECCCHH
KVARFPKFDWPRIDAPFIRPGADMAALEAESVRQARAAFEAYPHDIACFIAEPIQGEGGD
HHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCC
RHFRPEFFVAMRALCDEFDALLIVDEVQTGCGITGTPWAYQQLGITPDVVAFGKKTQVCG
CCCCHHHHHHHHHHHHCCCEEEEEEEHHCCCCCCCCCCHHHHCCCCHHHHHCCCCCHHHH
VMAGRRVDEVTDNVFAVSSRINSTWGGNLTDMVRARRILEVIEADDLPACAARAGDYLQA
HHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
RLEELADEFPGVVLDVRGRGLMRAFSLPSQAQRDDLIRRLWERRVIMLASGVDSVRFRPA
HHHHHHHHCCCEEEEECCCCHHHHHCCCCCCHHHHHHHHHHHCCEEEEECCCCCCEECCC
LTVSRAELDAAVDAVREALR
EEHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]