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The map label for this gene is lrp [C]

Identifier: 108798242

GI number: 108798242

Start: 1380666

End: 1381166

Strand: Direct

Name: lrp [C]

Synonym: Mmcs_1271

Alternate gene names: 108798242

Gene position: 1380666-1381166 (Clockwise)

Preceding gene: 108798240

Following gene: 108798243

Centisome position: 24.2

GC content: 67.66

Gene sequence:

>501_bases
GTGCTCGGCTACAGTGCGGCCATGGGTGAACCCGACGAGCACCCGCATTCACCTGCGCCGCTCGATGAGATCGACCGCAT
CCTGGCGCGCGAACTCGTCGCGGACGGGCGCGCCACGCTCGCGCATCTGGCGGCCGCCGCCGGCCTGTCGGTGTCGGCGG
TGCAGTCACGGGTGCGCCGGTTGGAGGCGCGCGGCGTCGTCACGGGGTACCAGGCGAAGATCAACCCGGAAGCGGTCGGA
CACCAACTCTCGGCGTTCGTCGCGATCACCCCTCTCGATCCGTCTCAACCCGATGATGCGCCCGCGCGGCTCGAACACAT
AGCCGCGATCGAGTCGTGCCATTCGGTGGCCGGCGACGAGAGCTACGTGCTGCTGGTGCGGGTCGGATCGGCGCGAGCGC
TCGAGGATCTGCTGCAGCAGATCCGGACGGCAGCGAACGTGCGGACCCGAAGCACGATCATTCTACAGACATTTTACGAG
GGTCGGCAGCACGTACCGTAA

Upstream 100 bases:

>100_bases
CAGGAGAAGCCGCGTCAGACGCCATGGTCGTGGCGGAGGTGGTGGTCATCGCTGGTCCTTGTCCGTGAGTGGGGAGTGTC
GTACGTGTTTCGGGTGTCGC

Downstream 100 bases:

>100_bases
ATTTTCCTGTCGTGGGCCCCTCCTGAGGGTTGTTTGCGTGCATCGCAGCGCGGTTGCCCGCCATTTTGGAGGTGCCGGAC
AGTAGCCGCTCCGCGCGCTC

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MLGYSAAMGEPDEHPHSPAPLDEIDRILARELVADGRATLAHLAAAAGLSVSAVQSRVRRLEARGVVTGYQAKINPEAVG
HQLSAFVAITPLDPSQPDDAPARLEHIAAIESCHSVAGDESYVLLVRVGSARALEDLLQQIRTAANVRTRSTIILQTFYE
GRQHVP

Sequences:

>Translated_166_residues
MLGYSAAMGEPDEHPHSPAPLDEIDRILARELVADGRATLAHLAAAAGLSVSAVQSRVRRLEARGVVTGYQAKINPEAVG
HQLSAFVAITPLDPSQPDDAPARLEHIAAIESCHSVAGDESYVLLVRVGSARALEDLLQQIRTAANVRTRSTIILQTFYE
GRQHVP
>Mature_166_residues
MLGYSAAMGEPDEHPHSPAPLDEIDRILARELVADGRATLAHLAAAAGLSVSAVQSRVRRLEARGVVTGYQAKINPEAVG
HQLSAFVAITPLDPSQPDDAPARLEHIAAIESCHSVAGDESYVLLVRVGSARALEDLLQQIRTAANVRTRSTIILQTFYE
GRQHVP

Specific function: Mediates A Global Response To Leucine. Exogenous Leucine Affects The Expression Of A Number Of Different Operons; Lrp Mediates This Effect For At Least Some Of These Operons. For Example It Is Regulator Of The Branched-Chain Amino Acid Transport Genes. [

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=150, Percent_Identity=34, Blast_Score=78, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR013196
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF08279 HTH_11 [H]

EC number: NA

Molecular weight: Translated: 17787; Mature: 17787

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGYSAAMGEPDEHPHSPAPLDEIDRILARELVADGRATLAHLAAAAGLSVSAVQSRVRR
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHH
LEARGVVTGYQAKINPEAVGHQLSAFVAITPLDPSQPDDAPARLEHIAAIESCHSVAGDE
HHHCCCEECCCCCCCHHHHHHHHEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
SYVLLVRVGSARALEDLLQQIRTAANVRTRSTIILQTFYEGRQHVP
CEEEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLGYSAAMGEPDEHPHSPAPLDEIDRILARELVADGRATLAHLAAAAGLSVSAVQSRVRR
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHH
LEARGVVTGYQAKINPEAVGHQLSAFVAITPLDPSQPDDAPARLEHIAAIESCHSVAGDE
HHHCCCEECCCCCCCHHHHHHHHEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
SYVLLVRVGSARALEDLLQQIRTAANVRTRSTIILQTFYEGRQHVP
CEEEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]