Definition Mycobacterium sp. MCS chromosome, complete genome.
Accession NC_008146
Length 5,705,448

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The map label for this gene is yhdF [H]

Identifier: 108798224

GI number: 108798224

Start: 1356546

End: 1357316

Strand: Direct

Name: yhdF [H]

Synonym: Mmcs_1253

Alternate gene names: 108798224

Gene position: 1356546-1357316 (Clockwise)

Preceding gene: 108798223

Following gene: 108798226

Centisome position: 23.78

GC content: 69.91

Gene sequence:

>771_bases
ATGGACCGCGCGAAGTTCGACCGACTCTTCGATCTGACCGGCCGCACCGCCGTCGTCACCGGCGGCACCCGCGGTATCGG
TCTCGCGCTCGCCGAGGGTTTCGCGCTGGCCGGCGCCCGGGTGGTGGTCGCCAGTCGCAAGCCCGACGCCTGTGAACGCG
CCGCCGAGCATCTGCGCGGGCTCGGCGCACAGGCTGTCGGCGTCCCCACCCACCTCGGGGACATCGACGCGCTCGAGGCG
CTGGTCACCCGCACCGTCGAGGAGTTCGGCGGCATCGACGTGTTGGTGAACAACGCCGCGAACGCGCTGGCGCAACCGCT
GGGGGAGATGACGCCCGAGGCGTGGACGAAGTCCTACGACGTCAACCTGCGCGGCCCGGTGTTCCTCGTACAGCACGCGC
TGCCGCACCTGAAGGCCAGCGCGCACGCCGCGGTCCTGAACACGGTGTCGGTGGGCGCGTTCAACTTCGCGCCGAACGTG
TCGATGTACGCCGCGGGCAAGGCGGCGCTGCTGTCGTTCACCCGGTCGATGGCCGCTGCCTACGCGCCGTACGGCATCCG
CGTGAACGCGCTGGCGCCCGGCCCCGTCGACACCGACATGATGCGCAACAATTCGCAGGAGGCAATCGACGCGATGGCCG
GGGCCACGCTGATGAACCGGTTGGCATCACCGGACGAAATGGTCGGCGCCGCACTGTTGTTGGTCTCCGACGCCGGCAGC
TACCTGACCGGTCAGGCGATCATCGTGGACGGTGGCGGAACGCCTCGCTAG

Upstream 100 bases:

>100_bases
CGTGCCGCCACCGCCGGTGGGCAACATCGATGCCTGCGTGAATGTGGGCCGCCGGATCAGCGTCAGCGGCTGCATCTGAG
CGGCGTGGTTCACTGACGCG

Downstream 100 bases:

>100_bases
CTTCGCGCACCTCACCGGTGGTCGACGCCAGGATCTGGCTGCGGTTCTCCAGGTGCAGCGCCTGTTCGAGGCTGCCCGCC
GCGAGGTTCGCCCACAGCAC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MDRAKFDRLFDLTGRTAVVTGGTRGIGLALAEGFALAGARVVVASRKPDACERAAEHLRGLGAQAVGVPTHLGDIDALEA
LVTRTVEEFGGIDVLVNNAANALAQPLGEMTPEAWTKSYDVNLRGPVFLVQHALPHLKASAHAAVLNTVSVGAFNFAPNV
SMYAAGKAALLSFTRSMAAAYAPYGIRVNALAPGPVDTDMMRNNSQEAIDAMAGATLMNRLASPDEMVGAALLLVSDAGS
YLTGQAIIVDGGGTPR

Sequences:

>Translated_256_residues
MDRAKFDRLFDLTGRTAVVTGGTRGIGLALAEGFALAGARVVVASRKPDACERAAEHLRGLGAQAVGVPTHLGDIDALEA
LVTRTVEEFGGIDVLVNNAANALAQPLGEMTPEAWTKSYDVNLRGPVFLVQHALPHLKASAHAAVLNTVSVGAFNFAPNV
SMYAAGKAALLSFTRSMAAAYAPYGIRVNALAPGPVDTDMMRNNSQEAIDAMAGATLMNRLASPDEMVGAALLLVSDAGS
YLTGQAIIVDGGGTPR
>Mature_256_residues
MDRAKFDRLFDLTGRTAVVTGGTRGIGLALAEGFALAGARVVVASRKPDACERAAEHLRGLGAQAVGVPTHLGDIDALEA
LVTRTVEEFGGIDVLVNNAANALAQPLGEMTPEAWTKSYDVNLRGPVFLVQHALPHLKASAHAAVLNTVSVGAFNFAPNV
SMYAAGKAALLSFTRSMAAAYAPYGIRVNALAPGPVDTDMMRNNSQEAIDAMAGATLMNRLASPDEMVGAALLLVSDAGS
YLTGQAIIVDGGGTPR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=247, Percent_Identity=36.8421052631579, Blast_Score=158, Evalue=4e-39,
Organism=Homo sapiens, GI5031737, Length=257, Percent_Identity=33.4630350194552, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI126723750, Length=250, Percent_Identity=34, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI33667109, Length=203, Percent_Identity=36.9458128078818, Blast_Score=126, Evalue=2e-29,
Organism=Homo sapiens, GI126723191, Length=192, Percent_Identity=36.4583333333333, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI19923817, Length=250, Percent_Identity=27.6, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI7705925, Length=247, Percent_Identity=34.8178137651822, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI10190704, Length=246, Percent_Identity=31.7073170731707, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI4503301, Length=220, Percent_Identity=29.5454545454545, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI66933014, Length=250, Percent_Identity=28, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI59889578, Length=230, Percent_Identity=31.7391304347826, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI40254992, Length=245, Percent_Identity=29.3877551020408, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI7706318, Length=200, Percent_Identity=28, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI20149619, Length=195, Percent_Identity=30.7692307692308, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI302344755, Length=107, Percent_Identity=36.4485981308411, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI31542939, Length=204, Percent_Identity=27.4509803921569, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI209862901, Length=203, Percent_Identity=28.5714285714286, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI19923983, Length=203, Percent_Identity=28.5714285714286, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI4504505, Length=193, Percent_Identity=30.0518134715026, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI40254986, Length=201, Percent_Identity=30.8457711442786, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI4758504, Length=253, Percent_Identity=27.6679841897233, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI32455239, Length=218, Percent_Identity=29.3577981651376, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI5031765, Length=218, Percent_Identity=29.3577981651376, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI15277342, Length=246, Percent_Identity=27.6422764227642, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI223718074, Length=204, Percent_Identity=31.8627450980392, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI225579078, Length=213, Percent_Identity=28.169014084507, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI142976729, Length=225, Percent_Identity=23.1111111111111, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI210032110, Length=202, Percent_Identity=24.2574257425743, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI7657478, Length=189, Percent_Identity=30.1587301587302, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI87082100, Length=252, Percent_Identity=34.9206349206349, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1790717, Length=247, Percent_Identity=33.6032388663968, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1789208, Length=254, Percent_Identity=32.6771653543307, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1787335, Length=243, Percent_Identity=31.2757201646091, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1787905, Length=243, Percent_Identity=33.3333333333333, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1789378, Length=247, Percent_Identity=32.7935222672065, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI87082160, Length=250, Percent_Identity=30, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1786812, Length=260, Percent_Identity=28.4615384615385, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1788459, Length=244, Percent_Identity=29.5081967213115, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI2367365, Length=242, Percent_Identity=28.9256198347107, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787820, Length=221, Percent_Identity=28.0542986425339, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI2367175, Length=243, Percent_Identity=28.3950617283951, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1786701, Length=201, Percent_Identity=26.865671641791, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=252, Percent_Identity=34.5238095238095, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17561402, Length=254, Percent_Identity=33.0708661417323, Blast_Score=138, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=30.1526717557252, Blast_Score=114, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17562906, Length=261, Percent_Identity=31.8007662835249, Blast_Score=110, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17562908, Length=269, Percent_Identity=33.457249070632, Blast_Score=110, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17560332, Length=260, Percent_Identity=32.3076923076923, Blast_Score=110, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI193204405, Length=261, Percent_Identity=31.8007662835249, Blast_Score=109, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI115534694, Length=250, Percent_Identity=31.2, Blast_Score=109, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17555706, Length=250, Percent_Identity=34, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17562904, Length=261, Percent_Identity=31.0344827586207, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17565030, Length=262, Percent_Identity=31.2977099236641, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71994600, Length=247, Percent_Identity=31.1740890688259, Blast_Score=102, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71994604, Length=245, Percent_Identity=30.2040816326531, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17538480, Length=260, Percent_Identity=31.5384615384615, Blast_Score=100, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=29.6153846153846, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17544670, Length=265, Percent_Identity=28.3018867924528, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17538486, Length=262, Percent_Identity=29.7709923664122, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17560220, Length=268, Percent_Identity=30.2238805970149, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17531453, Length=262, Percent_Identity=30.1526717557252, Blast_Score=98, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17560150, Length=264, Percent_Identity=27.6515151515151, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17551412, Length=260, Percent_Identity=29.6153846153846, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI25147288, Length=247, Percent_Identity=32.7935222672065, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI72000259, Length=260, Percent_Identity=30.3846153846154, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17536025, Length=249, Percent_Identity=29.718875502008, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17561272, Length=250, Percent_Identity=32, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17536651, Length=249, Percent_Identity=28.9156626506024, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17562990, Length=259, Percent_Identity=27.027027027027, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17563726, Length=258, Percent_Identity=28.2945736434109, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71982365, Length=196, Percent_Identity=32.6530612244898, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71997099, Length=206, Percent_Identity=27.6699029126214, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17538182, Length=252, Percent_Identity=29.7619047619048, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17508651, Length=252, Percent_Identity=25.3968253968254, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17558628, Length=192, Percent_Identity=31.25, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17555612, Length=210, Percent_Identity=28.0952380952381, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17568967, Length=193, Percent_Identity=26.4248704663212, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17558006, Length=218, Percent_Identity=26.1467889908257, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=194, Percent_Identity=23.7113402061856, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI72001658, Length=220, Percent_Identity=28.6363636363636, Blast_Score=68, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6324126, Length=247, Percent_Identity=27.1255060728745, Blast_Score=94, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6323882, Length=218, Percent_Identity=27.0642201834862, Blast_Score=79, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6322861, Length=194, Percent_Identity=28.8659793814433, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322226, Length=193, Percent_Identity=33.6787564766839, Blast_Score=68, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322227, Length=198, Percent_Identity=30.3030303030303, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21355319, Length=248, Percent_Identity=34.2741935483871, Blast_Score=145, Evalue=2e-35,
Organism=Drosophila melanogaster, GI23397609, Length=260, Percent_Identity=34.2307692307692, Blast_Score=107, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24643142, Length=250, Percent_Identity=33.6, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI21357041, Length=245, Percent_Identity=31.0204081632653, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21357673, Length=255, Percent_Identity=31.7647058823529, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24644337, Length=250, Percent_Identity=28, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI28571526, Length=245, Percent_Identity=28.1632653061224, Blast_Score=84, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24644339, Length=258, Percent_Identity=28.6821705426357, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21358495, Length=199, Percent_Identity=28.643216080402, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24639444, Length=246, Percent_Identity=28.8617886178862, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24641232, Length=209, Percent_Identity=29.1866028708134, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI116007236, Length=197, Percent_Identity=25.8883248730964, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24581726, Length=201, Percent_Identity=25.3731343283582, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI18859837, Length=191, Percent_Identity=30.8900523560209, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI161076371, Length=217, Percent_Identity=29.4930875576037, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI17737361, Length=248, Percent_Identity=26.6129032258064, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21356301, Length=196, Percent_Identity=28.0612244897959, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI221331218, Length=205, Percent_Identity=29.2682926829268, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24656154, Length=223, Percent_Identity=26.0089686098655, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI19922628, Length=223, Percent_Identity=26.0089686098655, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24665243, Length=205, Percent_Identity=29.2682926829268, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 26470; Mature: 26470

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MDRAKFDRLFDLTGRTAVVTGGTRGIGLALAEGFALAGARVVVASRKPDACERAAEHLRG
CCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHC
LGAQAVGVPTHLGDIDALEALVTRTVEEFGGIDVLVNNAANALAQPLGEMTPEAWTKSYD
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHHHCCHHHHCCCCC
VNLRGPVFLVQHALPHLKASAHAAVLNTVSVGAFNFAPNVSMYAAGKAALLSFTRSMAAA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCEECCCCCEEECCCHHHHHHHHHHHHHH
YAPYGIRVNALAPGPVDTDMMRNNSQEAIDAMAGATLMNRLASPDEMVGAALLLVSDAGS
HCCCCEEEEEECCCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHEEEEECCCC
YLTGQAIIVDGGGTPR
EEECCEEEECCCCCCC
>Mature Secondary Structure
MDRAKFDRLFDLTGRTAVVTGGTRGIGLALAEGFALAGARVVVASRKPDACERAAEHLRG
CCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHC
LGAQAVGVPTHLGDIDALEALVTRTVEEFGGIDVLVNNAANALAQPLGEMTPEAWTKSYD
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHHHCCHHHHCCCCC
VNLRGPVFLVQHALPHLKASAHAAVLNTVSVGAFNFAPNVSMYAAGKAALLSFTRSMAAA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCEECCCCCEEECCCHHHHHHHHHHHHHH
YAPYGIRVNALAPGPVDTDMMRNNSQEAIDAMAGATLMNRLASPDEMVGAALLLVSDAGS
HCCCCEEEEEECCCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHEEEEECCCC
YLTGQAIIVDGGGTPR
EEECCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]