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The map label for this gene is aroG [H]

Identifier: 108798132

GI number: 108798132

Start: 1257293

End: 1258345

Strand: Direct

Name: aroG [H]

Synonym: Mmcs_1161

Alternate gene names: 108798132

Gene position: 1257293-1258345 (Clockwise)

Preceding gene: 108798130

Following gene: 108798134

Centisome position: 22.04

GC content: 69.9

Gene sequence:

>1053_bases
ATGAACCTGGCGCAGATCGCCACCCCGCCGGCCACCTCCGACCGGCGCATCCGCAGCTTCAGCGCGATTCCCAGCCCGCA
CGAGGTGCTCGCGGAGTTCCCGCTGGGTGCCCGGCGCGCCGAGCGGGTGGCCCGCGACCGCACCGAGATCGCCGACATCC
TCGCCGGCCGCGACGACCGACTGCTGGTCGTGGTCGGTCCGTGCTCGGTGCACGATCCGGTCGCCGCGCTGAACTACGCA
AGCCGGCTCGCGAAGATCGCCGACGAACTCGGCGACCGGCTCAAGATCGTCATGCGCGTGTACTTCGAGAAGCCGCGGAC
GACGATCGGATGGAAGGGGCTGATCAACGATCCGGGGATGGACGGCACGTTCGATGTGTCGCGCGGTCTGCGCACCGCCC
GCCAGCTGCTGCTCGACATCATCGACATCGGCCTACCCGTCGGATGCGAGTTCCTGGAACCGACCAGCCCGCAGTACATC
GCCGACGCCGTCGCCTGGGGTGCCATCGGCGCCCGCACGACCGAATCGCAGGTGCACCGCCAACTCGCGTCGGGTCTGTC
GATGCCCGTCGGCTTCAAGAACGGCACCGACGGCAACATCCAGGTGGCCGTCGACGGGGTGAAGGCCGCCGCGGCCCAGC
ACGTCTTCTTCGGGATGGACGACTCCGGCCGTGGCGCAGTCGTGAGCACCGAGGGCAACGAGGACTGCCACGTCATCCTG
CGCGGCGGTACCGACGGACCCAACTACCACGCGGATGCCGTGCAGGCCGCCGCCGCCAAGCTGACCGCCGCCGGACTGCC
GGGACGGGTCGTCGTCGACTGCAGCCACGCCAACTCCGGCAAGGACCACATCCGCCAGGCGGCGGTGGCCGCCGAGGTGG
CCCAGCTGATCCGCGACGGGCTTCCGGTCAGCGGGGTGATGCTGGAGAGCTTCCTGGTCGGGGGTGCGCAGTCCGCCGAG
TCGCGGCCGCTCACTTACGGGCAATCGGTCACCGACAAATGCATGGACTGGACCGCGACGGATCTGGTGCTGCGAGAACT
GGCGGCGCGCTAG

Upstream 100 bases:

>100_bases
CACCCGGAGCCCAGGCAGTGACCACACGGTCGCTGCCTTTCGTCATTCAAGGGCACCGGACCGTCACGCAGGTGCCCATC
CCCAGAAAGGCACCTCGAGA

Downstream 100 bases:

>100_bases
GCGGCTGTGGAATCCGTCGTCCGAGAACGGAGACGCCCCATCCCGGCGTTTGCTGAGATGGGGCGTTCTCGTTCGCTGAA
CGGCTCGGTCAGGCGGTCCG

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MNLAQIATPPATSDRRIRSFSAIPSPHEVLAEFPLGARRAERVARDRTEIADILAGRDDRLLVVVGPCSVHDPVAALNYA
SRLAKIADELGDRLKIVMRVYFEKPRTTIGWKGLINDPGMDGTFDVSRGLRTARQLLLDIIDIGLPVGCEFLEPTSPQYI
ADAVAWGAIGARTTESQVHRQLASGLSMPVGFKNGTDGNIQVAVDGVKAAAAQHVFFGMDDSGRGAVVSTEGNEDCHVIL
RGGTDGPNYHADAVQAAAAKLTAAGLPGRVVVDCSHANSGKDHIRQAAVAAEVAQLIRDGLPVSGVMLESFLVGGAQSAE
SRPLTYGQSVTDKCMDWTATDLVLRELAAR

Sequences:

>Translated_350_residues
MNLAQIATPPATSDRRIRSFSAIPSPHEVLAEFPLGARRAERVARDRTEIADILAGRDDRLLVVVGPCSVHDPVAALNYA
SRLAKIADELGDRLKIVMRVYFEKPRTTIGWKGLINDPGMDGTFDVSRGLRTARQLLLDIIDIGLPVGCEFLEPTSPQYI
ADAVAWGAIGARTTESQVHRQLASGLSMPVGFKNGTDGNIQVAVDGVKAAAAQHVFFGMDDSGRGAVVSTEGNEDCHVIL
RGGTDGPNYHADAVQAAAAKLTAAGLPGRVVVDCSHANSGKDHIRQAAVAAEVAQLIRDGLPVSGVMLESFLVGGAQSAE
SRPLTYGQSVTDKCMDWTATDLVLRELAAR
>Mature_350_residues
MNLAQIATPPATSDRRIRSFSAIPSPHEVLAEFPLGARRAERVARDRTEIADILAGRDDRLLVVVGPCSVHDPVAALNYA
SRLAKIADELGDRLKIVMRVYFEKPRTTIGWKGLINDPGMDGTFDVSRGLRTARQLLLDIIDIGLPVGCEFLEPTSPQYI
ADAVAWGAIGARTTESQVHRQLASGLSMPVGFKNGTDGNIQVAVDGVKAAAAQHVFFGMDDSGRGAVVSTEGNEDCHVIL
RGGTDGPNYHADAVQAAAAKLTAAGLPGRVVVDCSHANSGKDHIRQAAVAAEVAQLIRDGLPVSGVMLESFLVGGAQSAE
SRPLTYGQSVTDKCMDWTATDLVLRELAAR

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786969, Length=337, Percent_Identity=57.2700296735905, Blast_Score=382, Evalue=1e-107,
Organism=Escherichia coli, GI1788953, Length=340, Percent_Identity=52.0588235294118, Blast_Score=362, Evalue=1e-101,
Organism=Escherichia coli, GI1787996, Length=340, Percent_Identity=48.2352941176471, Blast_Score=339, Evalue=1e-94,
Organism=Saccharomyces cerevisiae, GI6319726, Length=343, Percent_Identity=51.0204081632653, Blast_Score=339, Evalue=4e-94,
Organism=Saccharomyces cerevisiae, GI6320240, Length=345, Percent_Identity=46.9565217391304, Blast_Score=333, Evalue=2e-92,

Paralogues:

None

Copy number: 600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 37154; Mature: 37154

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLAQIATPPATSDRRIRSFSAIPSPHEVLAEFPLGARRAERVARDRTEIADILAGRDDR
CCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCC
LLVVVGPCSVHDPVAALNYASRLAKIADELGDRLKIVMRVYFEKPRTTIGWKGLINDPGM
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
DGTFDVSRGLRTARQLLLDIIDIGLPVGCEFLEPTSPQYIADAVAWGAIGARTTESQVHR
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHH
QLASGLSMPVGFKNGTDGNIQVAVDGVKAAAAQHVFFGMDDSGRGAVVSTEGNEDCHVIL
HHHCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHEEEECCCCCCEEEEECCCCCCEEEEE
RGGTDGPNYHADAVQAAAAKLTAAGLPGRVVVDCSHANSGKDHIRQAAVAAEVAQLIRDG
ECCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCC
LPVSGVMLESFLVGGAQSAESRPLTYGQSVTDKCMDWTATDLVLRELAAR
CCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHCC
>Mature Secondary Structure
MNLAQIATPPATSDRRIRSFSAIPSPHEVLAEFPLGARRAERVARDRTEIADILAGRDDR
CCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCC
LLVVVGPCSVHDPVAALNYASRLAKIADELGDRLKIVMRVYFEKPRTTIGWKGLINDPGM
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
DGTFDVSRGLRTARQLLLDIIDIGLPVGCEFLEPTSPQYIADAVAWGAIGARTTESQVHR
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHH
QLASGLSMPVGFKNGTDGNIQVAVDGVKAAAAQHVFFGMDDSGRGAVVSTEGNEDCHVIL
HHHCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHEEEECCCCCCEEEEECCCCCCEEEEE
RGGTDGPNYHADAVQAAAAKLTAAGLPGRVVVDCSHANSGKDHIRQAAVAAEVAQLIRDG
ECCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCC
LPVSGVMLESFLVGGAQSAESRPLTYGQSVTDKCMDWTATDLVLRELAAR
CCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8097175; 12948626 [H]