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The map label for this gene is yfhR [C]

Identifier: 108797685

GI number: 108797685

Start: 756469

End: 757296

Strand: Direct

Name: yfhR [C]

Synonym: Mmcs_0705

Alternate gene names: 108797685

Gene position: 756469-757296 (Clockwise)

Preceding gene: 108797684

Following gene: 108797686

Centisome position: 13.26

GC content: 72.22

Gene sequence:

>828_bases
GTGCGCCGCTGGGCACGCCTTGTCGTTATCGTCGTCCTCGTGGCCAACGGAGCATTGGCGCTGCTTTGGAACCAGCAGCG
GCGGCTGATCTACTTCCCGGCCCCGGGACCCGTGCCGTCGGCGACCGCGGTGTGGTCCGGCGCCCGCGACGTCGTGGTGC
GCACCGCCGACGGTGTGGATTTGGGTGCCTGGTTCTTTGCGGCCGCCGACCGCGGGCCGGCCGTTCTGGTCTGCAACGGC
AACGGCGGTGACCGGTCGATGCGGGCGGCGTTGGCGCTGGCGCTGCGGCGAATGGGGTTGTCGGTCCTGTTGTTCGACTA
CCGCGGTTACGGCGGCAACCCGGGGCGCCCCACCGAGGACGGTCTGGCCGCCGACGCCAGGGCGGCCCGCGACTGGCTGG
CCGCGCAACCGGAGGTCGATCCGGACCGCCTCGCCTACTTCGGCGAATCGCTCGGCGGCGCGGTCGCCGTCGGCCTGGCT
GCCGCGCGTCCACCCGCCGCGCTGGTGTTGCGGTCACCGTTCACCTCACTGGCCGATGTCGGCGCGGTGCACTACCCGTG
GCTGCCGGTGCGGCGTCTCCTGCTGGATCGGTATCCGTCGATCGAGCGGATCGCGGGGATTCACGCGCCGTTGCTGGTGA
TCGCCGGCGACCGCGACGACATCGTGCCGGCCGGGCTGAGCCGACGCCTGTACGACGCCGCCGCCGAACCGAAGGAGTTC
GTGCTCGTGCCCGGCGCCGGCCACAACGACCCGGAACTGCTCGACGGACCACAGATGCTCGAGGCGATCGAGCGGTTCCT
GCGGCACACCGCCGTCCTCGGCCCGTAG

Upstream 100 bases:

>100_bases
GCCTCACCCCGGCGGGCGGCCGAACAGTTGGGCTTCCGGGCCGTGGTGGATCCGCGGGACGGGCTGCGCGAGTTCGCCTT
CGCACCGCTGCGGGCGTGAC

Downstream 100 bases:

>100_bases
CACGGGGCGATACTGACTGCGTGAAAACCGCGATCTGTGAACAGTTCGGCATCGACTTCCCCCTCTTCGCGTTCAGCCAC
TGCCGCGACGTCGTCGCCGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MRRWARLVVIVVLVANGALALLWNQQRRLIYFPAPGPVPSATAVWSGARDVVVRTADGVDLGAWFFAAADRGPAVLVCNG
NGGDRSMRAALALALRRMGLSVLLFDYRGYGGNPGRPTEDGLAADARAARDWLAAQPEVDPDRLAYFGESLGGAVAVGLA
AARPPAALVLRSPFTSLADVGAVHYPWLPVRRLLLDRYPSIERIAGIHAPLLVIAGDRDDIVPAGLSRRLYDAAAEPKEF
VLVPGAGHNDPELLDGPQMLEAIERFLRHTAVLGP

Sequences:

>Translated_275_residues
MRRWARLVVIVVLVANGALALLWNQQRRLIYFPAPGPVPSATAVWSGARDVVVRTADGVDLGAWFFAAADRGPAVLVCNG
NGGDRSMRAALALALRRMGLSVLLFDYRGYGGNPGRPTEDGLAADARAARDWLAAQPEVDPDRLAYFGESLGGAVAVGLA
AARPPAALVLRSPFTSLADVGAVHYPWLPVRRLLLDRYPSIERIAGIHAPLLVIAGDRDDIVPAGLSRRLYDAAAEPKEF
VLVPGAGHNDPELLDGPQMLEAIERFLRHTAVLGP
>Mature_275_residues
MRRWARLVVIVVLVANGALALLWNQQRRLIYFPAPGPVPSATAVWSGARDVVVRTADGVDLGAWFFAAADRGPAVLVCNG
NGGDRSMRAALALALRRMGLSVLLFDYRGYGGNPGRPTEDGLAADARAARDWLAAQPEVDPDRLAYFGESLGGAVAVGLA
AARPPAALVLRSPFTSLADVGAVHYPWLPVRRLLLDRYPSIERIAGIHAPLLVIAGDRDDIVPAGLSRRLYDAAAEPKEF
VLVPGAGHNDPELLDGPQMLEAIERFLRHTAVLGP

Specific function: Unknown

COG id: COG1073

COG function: function code R; Hydrolases of the alpha/beta superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To S.pombe bem46 and yeast YNL320w [H]

Homologues:

Organism=Homo sapiens, GI49355781, Length=266, Percent_Identity=28.1954887218045, Blast_Score=111, Evalue=8e-25,
Organism=Homo sapiens, GI71051600, Length=225, Percent_Identity=31.5555555555556, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI71051602, Length=225, Percent_Identity=31.5555555555556, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI194306564, Length=195, Percent_Identity=34.3589743589744, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI194306562, Length=195, Percent_Identity=34.3589743589744, Blast_Score=107, Evalue=8e-24,
Organism=Homo sapiens, GI151301175, Length=220, Percent_Identity=32.2727272727273, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI109689718, Length=252, Percent_Identity=30.5555555555556, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI24308097, Length=220, Percent_Identity=32.2727272727273, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI32451492, Length=253, Percent_Identity=30.4347826086957, Blast_Score=98, Evalue=7e-21,
Organism=Homo sapiens, GI32528310, Length=241, Percent_Identity=31.5352697095436, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI226510965, Length=263, Percent_Identity=31.5589353612167, Blast_Score=104, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI71988362, Length=181, Percent_Identity=33.1491712707182, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17566318, Length=221, Percent_Identity=28.5067873303167, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17532877, Length=214, Percent_Identity=29.4392523364486, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324009, Length=268, Percent_Identity=28.3582089552239, Blast_Score=95, Evalue=1e-20,
Organism=Drosophila melanogaster, GI17137566, Length=276, Percent_Identity=31.8840579710145, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI281362521, Length=195, Percent_Identity=30.7692307692308, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI281362519, Length=195, Percent_Identity=30.7692307692308, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI28571878, Length=195, Percent_Identity=30.7692307692308, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24655467, Length=187, Percent_Identity=29.9465240641711, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24655464, Length=185, Percent_Identity=30.2702702702703, Blast_Score=74, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002925 [H]

Pfam domain/function: PF01738 DLH [H]

EC number: NA

Molecular weight: Translated: 29400; Mature: 29400

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRWARLVVIVVLVANGALALLWNQQRRLIYFPAPGPVPSATAVWSGARDVVVRTADGVD
CCHHHHHHHHHHHHHCCCEEEEEECCCEEEEECCCCCCCCCHHHHCCCCEEEEEECCCCC
LGAWFFAAADRGPAVLVCNGNGGDRSMRAALALALRRMGLSVLLFDYRGYGGNPGRPTED
HHHHHEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCC
GLAADARAARDWLAAQPEVDPDRLAYFGESLGGAVAVGLAAARPPAALVLRSPFTSLADV
CCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCHHHHHHHHCCCCCCEEEEECCHHHHHHC
GAVHYPWLPVRRLLLDRYPSIERIAGIHAPLLVIAGDRDDIVPAGLSRRLYDAAAEPKEF
CCCCCCCHHHHHHHHHCCCCHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCEE
VLVPGAGHNDPELLDGPQMLEAIERFLRHTAVLGP
EEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRRWARLVVIVVLVANGALALLWNQQRRLIYFPAPGPVPSATAVWSGARDVVVRTADGVD
CCHHHHHHHHHHHHHCCCEEEEEECCCEEEEECCCCCCCCCHHHHCCCCEEEEEECCCCC
LGAWFFAAADRGPAVLVCNGNGGDRSMRAALALALRRMGLSVLLFDYRGYGGNPGRPTED
HHHHHEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCC
GLAADARAARDWLAAQPEVDPDRLAYFGESLGGAVAVGLAAARPPAALVLRSPFTSLADV
CCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCHHHHHHHHCCCCCCEEEEECCHHHHHHC
GAVHYPWLPVRRLLLDRYPSIERIAGIHAPLLVIAGDRDDIVPAGLSRRLYDAAAEPKEF
CCCCCCCHHHHHHHHHCCCCHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCEE
VLVPGAGHNDPELLDGPQMLEAIERFLRHTAVLGP
EEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]