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The map label for this gene is galE [C]

Identifier: 108797684

GI number: 108797684

Start: 755436

End: 756467

Strand: Direct

Name: galE [C]

Synonym: Mmcs_0704

Alternate gene names: 108797684

Gene position: 755436-756467 (Clockwise)

Preceding gene: 108797683

Following gene: 108797685

Centisome position: 13.24

GC content: 71.8

Gene sequence:

>1032_bases
GTGAGGGTGCTGCTGACCGGGGCCGCCGGATTCATCGGCTCGCGGGTGCGCGCGGCGCTGGAATCGGCGGGCCACGAGGT
CGTCGCCGTCGACGTGATGCTGCCCGCCGCCCACGGCGGAGCCGCACCGCTGCCCGAGGACACACACCGCGTCGACGTCC
GTGACGCGGACGCCCTGGCCCCGCTGCTCGAGGGGGTCGACGCCGTCTGCCACCAGGCCGCCGTGGTCGGCGCCGGGGTC
AACGCGGCCGACGCACCGTCGTACGGCAGTCACAACGACTACGGCACCACGGTGCTGCTCGCCGAGATGTTTGCCGCGGG
CGTGCGGAAACTGGTGCTGGCGTCGTCGATGGTGGTGTACGGGCAGGGCCGGTTCGACTGTCCCGCACACGGACCCGTCG
ACCCGTTACCGCGCACCCGGGCCGATCTGGACGCCGGTGTGTTCGAGCACCGCTGCCCCGTCGGCGGTGAGGAACTGCAG
TGGCGACTGGTCGGCGAGGACGAGCCGGTGCGGCCCCGAAGCCTCTACGCGGCAAGCAAAGCCGCCCAGGAGCACTACGC
GCTGGCATGGGCCGAAGCCACCGGCGGGTCGGTGGTGGCCCTGCGCTACCACAATGTCTACGGTCCGCACATGCCGCGCG
ACACCCCCTACAGCGGAGTGGCGGCCATCTTCCGCTCCGAACTCGAGAACGGGGACGTGCCGCGGGTTTTCGAGGACGGC
GGTCAGATGCGGGATTTCGTGCACGTCGACGACGTCGCGGCGGCGAACCTGGCCGCGATCGAGGCGGACCTGCCGGGTTT
CGAGGCCTTCAACGTGTGCTCCGGCCGGCCCATCTCCATCATCGAGGTCGCCAGCGAACTGTGCGAGATCCGCGGCGCCG
CACCGCCGTTGGTGACGGGTCAGTACCGCAGCGGCGACGTGCGCCACATCGTCGCCTCACCCCGGCGGGCGGCCGAACAG
TTGGGCTTCCGGGCCGTGGTGGATCCGCGGGACGGGCTGCGCGAGTTCGCCTTCGCACCGCTGCGGGCGTGA

Upstream 100 bases:

>100_bases
TCAAGAAGGTGGTGCACGAGGCGATCGATCAGGTCGCCGTCGAGCGGACGTGTGACCACTGCCTACCGCACGACGGTGTG
ACGCTGCCGATCGAGTTGCC

Downstream 100 bases:

>100_bases
CGTGCGCCGCTGGGCACGCCTTGTCGTTATCGTCGTCCTCGTGGCCAACGGAGCATTGGCGCTGCTTTGGAACCAGCAGC
GGCGGCTGATCTACTTCCCG

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MRVLLTGAAGFIGSRVRAALESAGHEVVAVDVMLPAAHGGAAPLPEDTHRVDVRDADALAPLLEGVDAVCHQAAVVGAGV
NAADAPSYGSHNDYGTTVLLAEMFAAGVRKLVLASSMVVYGQGRFDCPAHGPVDPLPRTRADLDAGVFEHRCPVGGEELQ
WRLVGEDEPVRPRSLYAASKAAQEHYALAWAEATGGSVVALRYHNVYGPHMPRDTPYSGVAAIFRSELENGDVPRVFEDG
GQMRDFVHVDDVAAANLAAIEADLPGFEAFNVCSGRPISIIEVASELCEIRGAAPPLVTGQYRSGDVRHIVASPRRAAEQ
LGFRAVVDPRDGLREFAFAPLRA

Sequences:

>Translated_343_residues
MRVLLTGAAGFIGSRVRAALESAGHEVVAVDVMLPAAHGGAAPLPEDTHRVDVRDADALAPLLEGVDAVCHQAAVVGAGV
NAADAPSYGSHNDYGTTVLLAEMFAAGVRKLVLASSMVVYGQGRFDCPAHGPVDPLPRTRADLDAGVFEHRCPVGGEELQ
WRLVGEDEPVRPRSLYAASKAAQEHYALAWAEATGGSVVALRYHNVYGPHMPRDTPYSGVAAIFRSELENGDVPRVFEDG
GQMRDFVHVDDVAAANLAAIEADLPGFEAFNVCSGRPISIIEVASELCEIRGAAPPLVTGQYRSGDVRHIVASPRRAAEQ
LGFRAVVDPRDGLREFAFAPLRA
>Mature_343_residues
MRVLLTGAAGFIGSRVRAALESAGHEVVAVDVMLPAAHGGAAPLPEDTHRVDVRDADALAPLLEGVDAVCHQAAVVGAGV
NAADAPSYGSHNDYGTTVLLAEMFAAGVRKLVLASSMVVYGQGRFDCPAHGPVDPLPRTRADLDAGVFEHRCPVGGEELQ
WRLVGEDEPVRPRSLYAASKAAQEHYALAWAEATGGSVVALRYHNVYGPHMPRDTPYSGVAAIFRSELENGDVPRVFEDG
GQMRDFVHVDDVAAANLAAIEADLPGFEAFNVCSGRPISIIEVASELCEIRGAAPPLVTGQYRSGDVRHIVASPRRAAEQ
LGFRAVVDPRDGLREFAFAPLRA

Specific function: Galactose metabolism; third step. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1790049, Length=290, Percent_Identity=26.551724137931, Blast_Score=71, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319493, Length=370, Percent_Identity=27.2972972972973, Blast_Score=93, Evalue=6e-20,
Organism=Drosophila melanogaster, GI19923002, Length=357, Percent_Identity=27.7310924369748, Blast_Score=90, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36327; Mature: 36327

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLLTGAAGFIGSRVRAALESAGHEVVAVDVMLPAAHGGAAPLPEDTHRVDVRDADALA
CEEEEECCHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCCCCCCEECCCCHHHHH
PLLEGVDAVCHQAAVVGAGVNAADAPSYGSHNDYGTTVLLAEMFAAGVRKLVLASSMVVY
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCEEEE
GQGRFDCPAHGPVDPLPRTRADLDAGVFEHRCPVGGEELQWRLVGEDEPVRPRSLYAASK
ECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHH
AAQEHYALAWAEATGGSVVALRYHNVYGPHMPRDTPYSGVAAIFRSELENGDVPRVFEDG
HHHHHHEEEEEECCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHCC
GQMRDFVHVDDVAAANLAAIEADLPGFEAFNVCSGRPISIIEVASELCEIRGAAPPLVTG
CCHHHEEEECCHHHHHHHEEECCCCCCCEECCCCCCCCHHHHHHHHHHHHCCCCCCCEEC
QYRSGDVRHIVASPRRAAEQLGFRAVVDPRDGLREFAFAPLRA
CCCCCCEEEECCCCHHHHHHCCCEEEECCHHHHHHHHCCCCCC
>Mature Secondary Structure
MRVLLTGAAGFIGSRVRAALESAGHEVVAVDVMLPAAHGGAAPLPEDTHRVDVRDADALA
CEEEEECCHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCCCCCCEECCCCHHHHH
PLLEGVDAVCHQAAVVGAGVNAADAPSYGSHNDYGTTVLLAEMFAAGVRKLVLASSMVVY
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCEEEE
GQGRFDCPAHGPVDPLPRTRADLDAGVFEHRCPVGGEELQWRLVGEDEPVRPRSLYAASK
ECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHH
AAQEHYALAWAEATGGSVVALRYHNVYGPHMPRDTPYSGVAAIFRSELENGDVPRVFEDG
HHHHHHEEEEEECCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHCC
GQMRDFVHVDDVAAANLAAIEADLPGFEAFNVCSGRPISIIEVASELCEIRGAAPPLVTG
CCHHHEEEECCHHHHHHHEEECCCCCCCEECCCCCCCCHHHHHHHHHHHHCCCCCCCEEC
QYRSGDVRHIVASPRRAAEQLGFRAVVDPRDGLREFAFAPLRA
CCCCCCEEEECCCCHHHHHHCCCEEEECCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]