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The map label for this gene is murB [H]

Identifier: 108797633

GI number: 108797633

Start: 713755

End: 714807

Strand: Direct

Name: murB [H]

Synonym: Mmcs_0653

Alternate gene names: 108797633

Gene position: 713755-714807 (Clockwise)

Preceding gene: 108797629

Following gene: 108797634

Centisome position: 12.51

GC content: 71.23

Gene sequence:

>1053_bases
GTGACCGGTCAGGAACTCGCGGGCGCGGAGGTCGAAGCCGACGTCGCGCTGGCTCCCTTGACCACGCTGCGGGTCGGACC
GGTCGCGCGGCGGCTCATCACCGCGACCAGCACCGAACAACTCGTCGCCGCCCTGCGCGCACCCGTCGGCCGGGACGCGC
TGATCCTCGCCGGCGGTTCGAACGTGGTGCTCGCCGACGACATGTCCGACCTCACGGTGATCCGGGTGGCCAACAGCGAG
ATCACCGTGCGCGACGGCATCGTGCGCGCCGAGGCGGGTGCGAACTGGGACGACGTCGTGGTCACCGCGCTGGCACACGG
CCTCGGCGGGTTGGAGTGCCTGTCGGGAATCCCCGGTTCGGCAGGGGCGACACCGGTGCAGAACGTCGGCGCCTACGGGT
CCGAGGTCGCCGACACCATCCGGCGCGTGCGGCTGTTCGACCGACGCACCGGCCGAGACGATTGGGTGACACCGCAGGAC
ATGGCCTTCGGGTACCGAACCAGCGTGTTGAAGCACTCCGATCACGCCGTGGTGCTCGAGGTGGAGTTCGCGCTCGACGT
CGGGGGCCGCAGCGCGCCGCTGCGCTACGGCGAACTGGCCAGGGCGCTCGACGTGGAACCGGGCGGCCGCGCCGATCCGG
TCGCGGTGCGCGACGCGGTGCTGGCGCTGCGCCGCGGTAAGGGCATGGTGCTCGACGAACCCGACCGCGACACGTGGAGC
GTCGGATCGTTCTTCACCAACCCCGTGGTCACGACGGCGCAACACGAACGCCTCGCCGCCGAGGTGGACGGTCCGGTGCC
CAGCTACCCCGCCCCGGACGGGGTGAAGCTGGCCGCCGGCTGGCTGGTGGAACACGCCGGGTTCGGCAAGGGTTACCCCG
GCGACGACGCCCCGGCCCGGTTGTCGACCAAACACGCGCTTGCTGTGACCAATCGGGGCCATGCGACCACAGCGGACGTG
ATCGCGCTGGCCAGGACGGTGCGCGACGGTGTGCGAACCACCTTCGGGATCGAACTCACCCCCGAGCCGACACTGGTCGG
CTGCACTCTCTAG

Upstream 100 bases:

>100_bases
TGGTCGCTGAACGCCCGGTGGACATCTTCGACGGTGCCCTCGTAGTCGGCGGCCAAGTCGAATGAACGCGGCATAGCTGG
CCACGCTACCGTTACCGCCC

Downstream 100 bases:

>100_bases
GTATGTTGGGTACACGTGAGTGCCGCCGACAAGCTGCCGCCCATGAATCGGCGGCGTGCCCTGACCGCCCTGGCGGTCGG
ACTCGTCGCGCCCGGAGCGC

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MTGQELAGAEVEADVALAPLTTLRVGPVARRLITATSTEQLVAALRAPVGRDALILAGGSNVVLADDMSDLTVIRVANSE
ITVRDGIVRAEAGANWDDVVVTALAHGLGGLECLSGIPGSAGATPVQNVGAYGSEVADTIRRVRLFDRRTGRDDWVTPQD
MAFGYRTSVLKHSDHAVVLEVEFALDVGGRSAPLRYGELARALDVEPGGRADPVAVRDAVLALRRGKGMVLDEPDRDTWS
VGSFFTNPVVTTAQHERLAAEVDGPVPSYPAPDGVKLAAGWLVEHAGFGKGYPGDDAPARLSTKHALAVTNRGHATTADV
IALARTVRDGVRTTFGIELTPEPTLVGCTL

Sequences:

>Translated_350_residues
MTGQELAGAEVEADVALAPLTTLRVGPVARRLITATSTEQLVAALRAPVGRDALILAGGSNVVLADDMSDLTVIRVANSE
ITVRDGIVRAEAGANWDDVVVTALAHGLGGLECLSGIPGSAGATPVQNVGAYGSEVADTIRRVRLFDRRTGRDDWVTPQD
MAFGYRTSVLKHSDHAVVLEVEFALDVGGRSAPLRYGELARALDVEPGGRADPVAVRDAVLALRRGKGMVLDEPDRDTWS
VGSFFTNPVVTTAQHERLAAEVDGPVPSYPAPDGVKLAAGWLVEHAGFGKGYPGDDAPARLSTKHALAVTNRGHATTADV
IALARTVRDGVRTTFGIELTPEPTLVGCTL
>Mature_349_residues
TGQELAGAEVEADVALAPLTTLRVGPVARRLITATSTEQLVAALRAPVGRDALILAGGSNVVLADDMSDLTVIRVANSEI
TVRDGIVRAEAGANWDDVVVTALAHGLGGLECLSGIPGSAGATPVQNVGAYGSEVADTIRRVRLFDRRTGRDDWVTPQDM
AFGYRTSVLKHSDHAVVLEVEFALDVGGRSAPLRYGELARALDVEPGGRADPVAVRDAVLALRRGKGMVLDEPDRDTWSV
GSFFTNPVVTTAQHERLAAEVDGPVPSYPAPDGVKLAAGWLVEHAGFGKGYPGDDAPARLSTKHALAVTNRGHATTADVI
ALARTVRDGVRTTFGIELTPEPTLVGCTL

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=341, Percent_Identity=33.1378299120235, Blast_Score=149, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 36675; Mature: 36544

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGQELAGAEVEADVALAPLTTLRVGPVARRLITATSTEQLVAALRAPVGRDALILAGGS
CCCCCCCCCCCCCCEEECCHHHHHHCHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEECCC
NVVLADDMSDLTVIRVANSEITVRDGIVRAEAGANWDDVVVTALAHGLGGLECLSGIPGS
CEEEECCCCCEEEEEEECCEEEEECCEEEECCCCCHHHHHHHHHHHCCCHHHHHCCCCCC
AGATPVQNVGAYGSEVADTIRRVRLFDRRTGRDDWVTPQDMAFGYRTSVLKHSDHAVVLE
CCCCCHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHEECCCCEEEEE
VEFALDVGGRSAPLRYGELARALDVEPGGRADPVAVRDAVLALRRGKGMVLDEPDRDTWS
EEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCEE
VGSFFTNPVVTTAQHERLAAEVDGPVPSYPAPDGVKLAAGWLVEHAGFGKGYPGDDAPAR
CCCCCCCCEEECCHHHHHHHHCCCCCCCCCCCCCCEEHHHHHHHHCCCCCCCCCCCCCCC
LSTKHALAVTNRGHATTADVIALARTVRDGVRTTFGIELTPEPTLVGCTL
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHEEEEEEECCCCCEEEECC
>Mature Secondary Structure 
TGQELAGAEVEADVALAPLTTLRVGPVARRLITATSTEQLVAALRAPVGRDALILAGGS
CCCCCCCCCCCCCEEECCHHHHHHCHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEECCC
NVVLADDMSDLTVIRVANSEITVRDGIVRAEAGANWDDVVVTALAHGLGGLECLSGIPGS
CEEEECCCCCEEEEEEECCEEEEECCEEEECCCCCHHHHHHHHHHHCCCHHHHHCCCCCC
AGATPVQNVGAYGSEVADTIRRVRLFDRRTGRDDWVTPQDMAFGYRTSVLKHSDHAVVLE
CCCCCHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHEECCCCEEEEE
VEFALDVGGRSAPLRYGELARALDVEPGGRADPVAVRDAVLALRRGKGMVLDEPDRDTWS
EEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCEE
VGSFFTNPVVTTAQHERLAAEVDGPVPSYPAPDGVKLAAGWLVEHAGFGKGYPGDDAPAR
CCCCCCCCEEECCHHHHHHHHCCCCCCCCCCCCCCEEHHHHHHHHCCCCCCCCCCCCCCC
LSTKHALAVTNRGHATTADVIALARTVRDGVRTTFGIELTPEPTLVGCTL
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHEEEEEEECCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA