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The map label for this gene is panF [C]

Identifier: 108797629

GI number: 108797629

Start: 710396

End: 711913

Strand: Direct

Name: panF [C]

Synonym: Mmcs_0649

Alternate gene names: 108797629

Gene position: 710396-711913 (Clockwise)

Preceding gene: 108797626

Following gene: 108797633

Centisome position: 12.45

GC content: 68.71

Gene sequence:

>1518_bases
ATGGTGCTCTTCGGCGTGGGTGTCAGCATCGCCGTGGTGGTGCTCGTCGGCTTCCTGGTGTCCCGGCGGATCGCGGGTGA
CAGCGCCAACTTCCTCGTCGGCGGCCGGACGCTGCCGCTGATACTCGTCGGCGGCGCGCTGATGGGTTCGGCGGTCGACA
CCAACGCGACGCTCGGCAACACCGACCTGGCGTCGGAGTTCGGCTTCTGGGCCGGTGCGTGTCTGCCGCTGGGGCTCGCG
CTGTGTCTGTTGTTCACCGGTCTGTTCTTCGCCAAGCCGATGAACCGGATGGGCCTGACGTCGTTCCCCGACTACTACCG
CCTGCGGTTCGGCCGCGGCGTGGAGGTCGCCGCCTCGGTGATGCTGATGATCGGCTTCTGCATCCTGGTGGCGGGGAACC
TGGTCGCGGGCGGGTTCCTGTTCAACTACTTCCTCGGCATCCCGTACTGGCTGGGCACGGTCGTCATCGCCGCGCTGGCC
GTCGCCTACACCGGGACCGGCGGGCTGTTGGCCGACGCGTACACCGCGATCATCCAGATGGCGATGATCCTGGTCGGGGC
GATGGGGCTGCTGATCTGGATGGTCCTCACCCATGGCCTGGCGATCGAAGAGGGGATGGGTCCGCTCGATCTCGGTCAGA
TGACCGATCCGGCGCAGGGCGCCACGGTCAACTGGGCGACGCTGATCGCGCTGGGGATCGGCGACATCGTGGCGATCGAC
TTCATGCAGCGGGTCTTCGCCGCGAAGTCGCCCGAGACCGCCCGCCGCGCGTGCTTCGGCGCCGCGGCCGGGGTGGTCGC
GATCTGCGTGCCGTTCGGGTTGGTCGTGCTGTCGGCCAGGGCGTTCCTGCCCGACGACCTCGATGGGCCGATCCTGCTGG
TGCTGCTCGACGGCTATGCGCCGCTGGCGTTGACGATCCTGGTGCTGTGCGGGTTGGTCGGCGCGTCCATGAGCACCGCC
AACGGCGCGATCCTCGCCATCTCCAACGTGTGCGTGCGCAATCTCGGCGGCGTGCGGCGGACGCACGTGCCGGGACAACC
GGATCCGCTGCTGCGCGCCACCCGGATCGCGATGGTCCCGGTGACGCTGCTGGCCATCGCGATCGCGATCTACGTCAAGC
AGACCGGGATCCTGCTCACCCTGGCGTTCGACCTGCTGCTCGCCTGCCTGGTGGTCCCGTTCATCCTCGGTCTGGTGTGG
CGCAAGGGCACGTCGACGGCGGCGCTGGCGTCGATCGTCGTGGGCCTGTCGGTGCGGCTGGTGCTGTTCGTGATGACGCC
GACGATGTACGGCCTCGACAACACGATCCTCTACATCCCCAACGGCGTGTTCGACGCGACGTTCGACGGGTGGCCGACGT
TCATCGCGTTCGCCGCATCGCTGGCCACCTACGTCGTCGTCGCCCTCGTCACCCCGGCCGCGCCGATCCGGGGACTCGAC
ATCCAGATGGCCGAGGACCTCGACGACGCGCTCGCCGCCGAACCGGTCACGGCGCGACCGTTGACCACGGCACGGTGA

Upstream 100 bases:

>100_bases
TGGCTCCGGACATGTGCCAAGCCTACGGCCGCCGTCGTTCGCAACACGCCCTTAACCCCGCTCGCGAACCGCTGTAACCG
CGCGGGGTTTGTCTGGGCCG

Downstream 100 bases:

>100_bases
GCACCCCGTCACGCATCCGTCGCCGCGGCGGCTCGACCGGAAACCCTTCTGCGGCAAGCAGATCCAGCATCGCGCGCCAG
CGGATCCGCGGGCCGAACAC

Product: Na+/solute symporter

Products: Na (I) [Cytoplasm]; pantothenate [Cytoplasm] [C]

Alternate protein names: Sodium/Solute Symporter; SodiumSolute Symporter; SodiumSolute Symporter Family Protein; High Affinity Choline Transporter; Sodium/Proline Symporter; SodiumProline Symporter; SSS Family Solute/Sodium Symporter; SodiumSolute Symporter Family; Na+/Proline Symporter Protein; SSS Sodium Solute Transporter Superfamily Protein; SoluteNa+ Symporter SSS Family; SSS Sodium Solute Transporter Superfamily; Sodium/Solute Symporter Transmembrane Protein; Sodium-Solute Symporter; Na+/Proline Symporter PutP; Na+ Solute Symporter

Number of amino acids: Translated: 505; Mature: 505

Protein sequence:

>505_residues
MVLFGVGVSIAVVVLVGFLVSRRIAGDSANFLVGGRTLPLILVGGALMGSAVDTNATLGNTDLASEFGFWAGACLPLGLA
LCLLFTGLFFAKPMNRMGLTSFPDYYRLRFGRGVEVAASVMLMIGFCILVAGNLVAGGFLFNYFLGIPYWLGTVVIAALA
VAYTGTGGLLADAYTAIIQMAMILVGAMGLLIWMVLTHGLAIEEGMGPLDLGQMTDPAQGATVNWATLIALGIGDIVAID
FMQRVFAAKSPETARRACFGAAAGVVAICVPFGLVVLSARAFLPDDLDGPILLVLLDGYAPLALTILVLCGLVGASMSTA
NGAILAISNVCVRNLGGVRRTHVPGQPDPLLRATRIAMVPVTLLAIAIAIYVKQTGILLTLAFDLLLACLVVPFILGLVW
RKGTSTAALASIVVGLSVRLVLFVMTPTMYGLDNTILYIPNGVFDATFDGWPTFIAFAASLATYVVVALVTPAAPIRGLD
IQMAEDLDDALAAEPVTARPLTTAR

Sequences:

>Translated_505_residues
MVLFGVGVSIAVVVLVGFLVSRRIAGDSANFLVGGRTLPLILVGGALMGSAVDTNATLGNTDLASEFGFWAGACLPLGLA
LCLLFTGLFFAKPMNRMGLTSFPDYYRLRFGRGVEVAASVMLMIGFCILVAGNLVAGGFLFNYFLGIPYWLGTVVIAALA
VAYTGTGGLLADAYTAIIQMAMILVGAMGLLIWMVLTHGLAIEEGMGPLDLGQMTDPAQGATVNWATLIALGIGDIVAID
FMQRVFAAKSPETARRACFGAAAGVVAICVPFGLVVLSARAFLPDDLDGPILLVLLDGYAPLALTILVLCGLVGASMSTA
NGAILAISNVCVRNLGGVRRTHVPGQPDPLLRATRIAMVPVTLLAIAIAIYVKQTGILLTLAFDLLLACLVVPFILGLVW
RKGTSTAALASIVVGLSVRLVLFVMTPTMYGLDNTILYIPNGVFDATFDGWPTFIAFAASLATYVVVALVTPAAPIRGLD
IQMAEDLDDALAAEPVTARPLTTAR
>Mature_505_residues
MVLFGVGVSIAVVVLVGFLVSRRIAGDSANFLVGGRTLPLILVGGALMGSAVDTNATLGNTDLASEFGFWAGACLPLGLA
LCLLFTGLFFAKPMNRMGLTSFPDYYRLRFGRGVEVAASVMLMIGFCILVAGNLVAGGFLFNYFLGIPYWLGTVVIAALA
VAYTGTGGLLADAYTAIIQMAMILVGAMGLLIWMVLTHGLAIEEGMGPLDLGQMTDPAQGATVNWATLIALGIGDIVAID
FMQRVFAAKSPETARRACFGAAAGVVAICVPFGLVVLSARAFLPDDLDGPILLVLLDGYAPLALTILVLCGLVGASMSTA
NGAILAISNVCVRNLGGVRRTHVPGQPDPLLRATRIAMVPVTLLAIAIAIYVKQTGILLTLAFDLLLACLVVPFILGLVW
RKGTSTAALASIVVGLSVRLVLFVMTPTMYGLDNTILYIPNGVFDATFDGWPTFIAFAASLATYVVVALVTPAAPIRGLD
IQMAEDLDDALAAEPVTARPLTTAR

Specific function: Catalyzes The Sodium-Dependent Uptake Of Extracellular Pantothenate. [C]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI11141885, Length=453, Percent_Identity=25.8278145695364, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17539284, Length=425, Percent_Identity=25.4117647058824, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24648033, Length=416, Percent_Identity=24.2788461538462, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21356865, Length=416, Percent_Identity=24.2788461538462, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 52633; Mature: 52633

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLFGVGVSIAVVVLVGFLVSRRIAGDSANFLVGGRTLPLILVGGALMGSAVDTNATLGN
CEEEECHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEHHEECHHHHCCCCCCCCCCCC
TDLASEFGFWAGACLPLGLALCLLFTGLFFAKPMNRMGLTSFPDYYRLRFGRGVEVAASV
CHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHCCCCHHHHHHH
MLMIGFCILVAGNLVAGGFLFNYFLGIPYWLGTVVIAALAVAYTGTGGLLADAYTAIIQM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
AMILVGAMGLLIWMVLTHGLAIEEGMGPLDLGQMTDPAQGATVNWATLIALGIGDIVAID
HHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
FMQRVFAAKSPETARRACFGAAAGVVAICVPFGLVVLSARAFLPDDLDGPILLVLLDGYA
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCH
PLALTILVLCGLVGASMSTANGAILAISNVCVRNLGGVRRTHVPGQPDPLLRATRIAMVP
HHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
VTLLAIAIAIYVKQTGILLTLAFDLLLACLVVPFILGLVWRKGTSTAALASIVVGLSVRL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
VLFVMTPTMYGLDNTILYIPNGVFDATFDGWPTFIAFAASLATYVVVALVTPAAPIRGLD
HHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
IQMAEDLDDALAAEPVTARPLTTAR
CHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MVLFGVGVSIAVVVLVGFLVSRRIAGDSANFLVGGRTLPLILVGGALMGSAVDTNATLGN
CEEEECHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEHHEECHHHHCCCCCCCCCCCC
TDLASEFGFWAGACLPLGLALCLLFTGLFFAKPMNRMGLTSFPDYYRLRFGRGVEVAASV
CHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHCCCCHHHHHHH
MLMIGFCILVAGNLVAGGFLFNYFLGIPYWLGTVVIAALAVAYTGTGGLLADAYTAIIQM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
AMILVGAMGLLIWMVLTHGLAIEEGMGPLDLGQMTDPAQGATVNWATLIALGIGDIVAID
HHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
FMQRVFAAKSPETARRACFGAAAGVVAICVPFGLVVLSARAFLPDDLDGPILLVLLDGYA
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCH
PLALTILVLCGLVGASMSTANGAILAISNVCVRNLGGVRRTHVPGQPDPLLRATRIAMVP
HHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
VTLLAIAIAIYVKQTGILLTLAFDLLLACLVVPFILGLVWRKGTSTAALASIVVGLSVRL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
VLFVMTPTMYGLDNTILYIPNGVFDATFDGWPTFIAFAASLATYVVVALVTPAAPIRGLD
HHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
IQMAEDLDDALAAEPVTARPLTTAR
CHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; pantothenate [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + pantothenate [Periplasm] = Na (I) [Cytoplasm] + pantothenate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA