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The map label for this gene is hbhA [H]

Identifier: 108797623

GI number: 108797623

Start: 706565

End: 707176

Strand: Direct

Name: hbhA [H]

Synonym: Mmcs_0643

Alternate gene names: 108797623

Gene position: 706565-707176 (Clockwise)

Preceding gene: 108797622

Following gene: 108797624

Centisome position: 12.38

GC content: 70.26

Gene sequence:

>612_bases
ATGGCTGAGAAGAACCCCCAGGTCGACATCGAAGACCTCAAGGCCCCGCTGCTCGCCGCCGTCGGCGCCGCCGATCTGGC
GCTGGCCACCGTCAACGAGATCGTCGCGAGCCTGCGTGACCGCGCCGAAGAGGCCCGCACCGACGCGAACAGCCGCGTCG
AGGAGAGCCGGGCCCGCATCAACAAACTGCAGGAAGAGCTTCCGACGCAGGTCACCGAGCTGCGGGAGCGGCTGACCGCC
GACGAGCTGCGCCGTGCCGCCGAGGGCTACGCCGAGGCCGCGCAGAGCACCTACGCCAAGCTCGTCGAGCGTGGCGAGGC
CGCACTCGAGCGGCTGCGCAGCCAGCCCGGCTTCACCGACGCCGCCAACCGGGTCGAGACCTACACCGATCAGGCCGTCG
AGCTGACCGAGCAGGCGCTGGGCAACGTGGCGACGCAGACCCGCGCCGTCGGTGAGCGCGCCGCCAAGCTCGTCGGTGTC
GAACTGCCGAAGAAGACCGAGGAGACCGCCGAGCCGGTCAAGGCGGCGGCCAAGAAGGCCCCGGCCAAGAAGGCTCCCGC
GAAGAAGGCTCCGGCCAAGAAGGCTCCGGCCAAGAAGGTCACCCAGAAGTAA

Upstream 100 bases:

>100_bases
GTAGACGAGGAGCCGACGACTGCACACACACCGATCAGTGGCGACCCGATCCAACGCGCACTAGAAACCACACCCGAAGA
TTCCCGAAAGGACATCCACC

Downstream 100 bases:

>100_bases
GTCGAATTCGACCGAAGGATGACGCCCGCATAGGCTGGTGAGGTGATACTTGCCGACCTTGCGGGCGTCATCGTCTTGGG
TCTCGTTCTGATCGTGTTGG

Product: hypothetical protein

Products: NA

Alternate protein names: Adhesin [H]

Number of amino acids: Translated: 203; Mature: 202

Protein sequence:

>203_residues
MAEKNPQVDIEDLKAPLLAAVGAADLALATVNEIVASLRDRAEEARTDANSRVEESRARINKLQEELPTQVTELRERLTA
DELRRAAEGYAEAAQSTYAKLVERGEAALERLRSQPGFTDAANRVETYTDQAVELTEQALGNVATQTRAVGERAAKLVGV
ELPKKTEETAEPVKAAAKKAPAKKAPAKKAPAKKAPAKKVTQK

Sequences:

>Translated_203_residues
MAEKNPQVDIEDLKAPLLAAVGAADLALATVNEIVASLRDRAEEARTDANSRVEESRARINKLQEELPTQVTELRERLTA
DELRRAAEGYAEAAQSTYAKLVERGEAALERLRSQPGFTDAANRVETYTDQAVELTEQALGNVATQTRAVGERAAKLVGV
ELPKKTEETAEPVKAAAKKAPAKKAPAKKAPAKKAPAKKVTQK
>Mature_202_residues
AEKNPQVDIEDLKAPLLAAVGAADLALATVNEIVASLRDRAEEARTDANSRVEESRARINKLQEELPTQVTELRERLTAD
ELRRAAEGYAEAAQSTYAKLVERGEAALERLRSQPGFTDAANRVETYTDQAVELTEQALGNVATQTRAVGERAAKLVGVE
LPKKTEETAEPVKAAAKKAPAKKAPAKKAPAKKAPAKKVTQK

Specific function: Required for extrapulmonary dissemination. Mediates adherence to epithelial cells by binding to sulfated glycoconjugates present at the surface of these cells; binds heparin, dextran sulfate, fucoidan and chondroitin sulfate. Promotes hemagglutination of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell surface [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.leprae hbhA [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020340
- ProDom:   PD082580 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 21878; Mature: 21747

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEKNPQVDIEDLKAPLLAAVGAADLALATVNEIVASLRDRAEEARTDANSRVEESRARI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NKLQEELPTQVTELRERLTADELRRAAEGYAEAAQSTYAKLVERGEAALERLRSQPGFTD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
AANRVETYTDQAVELTEQALGNVATQTRAVGERAAKLVGVELPKKTEETAEPVKAAAKKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHC
PAKKAPAKKAPAKKAPAKKVTQK
CCCCCCCCCCCCCCCCHHHHCCC
>Mature Secondary Structure 
AEKNPQVDIEDLKAPLLAAVGAADLALATVNEIVASLRDRAEEARTDANSRVEESRARI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NKLQEELPTQVTELRERLTADELRRAAEGYAEAAQSTYAKLVERGEAALERLRSQPGFTD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
AANRVETYTDQAVELTEQALGNVATQTRAVGERAAKLVGVELPKKTEETAEPVKAAAKKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHC
PAKKAPAKKAPAKKAPAKKVTQK
CCCCCCCCCCCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972; 11449276 [H]