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The map label for this gene is nagD [H]

Identifier: 108797579

GI number: 108797579

Start: 659156

End: 659971

Strand: Direct

Name: nagD [H]

Synonym: Mmcs_0599

Alternate gene names: 108797579

Gene position: 659156-659971 (Clockwise)

Preceding gene: 108797578

Following gene: 108797580

Centisome position: 11.55

GC content: 67.52

Gene sequence:

>816_bases
ATGGCGATCGGTGGAGTGCTCTTCGACATCGATGGCGTGCTGGTGACGTCGTGGCGGCCGATCGACGGTGCGGCCGAGGC
GTTGCGTGTGCTCTCCGACCATCAGATCGCCCGGTCCTATCTGACCAACACCACGACCAAGACGCGCAGGCAGATCGCCG
ATCTGCTCGTCGACGCCGGTATGGCGGTCACCGCCGACGAGGTGATCACCGCGGCGGTGCTCACCGCCGAGTACGTCCGC
GACCGCTACCCGGGCGCCCGGTGCTTCCTGGTGAACAGCGGCAGGATCGGGGAGGACATGCCCGGCGTCGATCTGGTGTA
CGCCGGGGAGTTCGGCCCCGACCACGTGCCCGAGACGCCGGATGTGGTGCTGCTCGGTGGCGCAGGCCCGGAGTACGACC
ATCTGACGTTGAGTTGGGTCTACGACTGGATGGCCCGCGGTGTGCCGGTGGTCGCCATGCACCGCAGCACGTCGTGGAAC
ACCGCCGACGGTCTGCGCATCGACACCGGTATGTACCTCATCGGGATGGAGGAGACGTCGGGGCGTAAGGCGACGGCGGT
CGGTAAACCGGCACCCGAGGGATTCCTGGCCGCCGCCGGCCGCCTGGGTGTCGACCCGGAGGAGATGTACATCGTCGGTG
ACGATCTCAACAACGACGTGCTCGCGGGTCAGGTGGTCGGGATGACCGGGGTGCTGGTGCGCACCGGCAAGTTCCGCCAG
GACACGTTGGACCGTTGGGCGGCAGACGAATTCGCCATGCAGCCGAACCACGTCATCGATTCGGTGGCCGACCTGCCCGG
CCTGCTGGGGCTGTGA

Upstream 100 bases:

>100_bases
GATCGTCGCGGCGGCGTCGCCGTGGGTGAGGGATGTCCCCTGGGCGCGTGATTGACCGGGTCCGAGTTGCACGTCGTCGG
CCGCGGTTTACTGTCGGCAC

Downstream 100 bases:

>100_bases
CAACGCGGCCGGTTGCGCGCTGCGGCAAGGCATCTCAACCGTTCGGCTGAGGCGCCGCACCCTGTGGGGGTGATTGGGTT
GAGCCCGTCACCTACCAGGG

Product: HAD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MAIGGVLFDIDGVLVTSWRPIDGAAEALRVLSDHQIARSYLTNTTTKTRRQIADLLVDAGMAVTADEVITAAVLTAEYVR
DRYPGARCFLVNSGRIGEDMPGVDLVYAGEFGPDHVPETPDVVLLGGAGPEYDHLTLSWVYDWMARGVPVVAMHRSTSWN
TADGLRIDTGMYLIGMEETSGRKATAVGKPAPEGFLAAAGRLGVDPEEMYIVGDDLNNDVLAGQVVGMTGVLVRTGKFRQ
DTLDRWAADEFAMQPNHVIDSVADLPGLLGL

Sequences:

>Translated_271_residues
MAIGGVLFDIDGVLVTSWRPIDGAAEALRVLSDHQIARSYLTNTTTKTRRQIADLLVDAGMAVTADEVITAAVLTAEYVR
DRYPGARCFLVNSGRIGEDMPGVDLVYAGEFGPDHVPETPDVVLLGGAGPEYDHLTLSWVYDWMARGVPVVAMHRSTSWN
TADGLRIDTGMYLIGMEETSGRKATAVGKPAPEGFLAAAGRLGVDPEEMYIVGDDLNNDVLAGQVVGMTGVLVRTGKFRQ
DTLDRWAADEFAMQPNHVIDSVADLPGLLGL
>Mature_270_residues
AIGGVLFDIDGVLVTSWRPIDGAAEALRVLSDHQIARSYLTNTTTKTRRQIADLLVDAGMAVTADEVITAAVLTAEYVRD
RYPGARCFLVNSGRIGEDMPGVDLVYAGEFGPDHVPETPDVVLLGGAGPEYDHLTLSWVYDWMARGVPVVAMHRSTSWNT
ADGLRIDTGMYLIGMEETSGRKATAVGKPAPEGFLAAAGRLGVDPEEMYIVGDDLNNDVLAGQVVGMTGVLVRTGKFRQD
TLDRWAADEFAMQPNHVIDSVADLPGLLGL

Specific function: Unknown

COG id: COG0647

COG function: function code G; Predicted sugar phosphatases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI14149777, Length=254, Percent_Identity=29.9212598425197, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI10092677, Length=282, Percent_Identity=30.4964539007092, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI269847098, Length=243, Percent_Identity=27.1604938271605, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI108796653, Length=292, Percent_Identity=27.7397260273973, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1786890, Length=269, Percent_Identity=30.4832713754647, Blast_Score=96, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17562356, Length=267, Percent_Identity=29.9625468164794, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17557870, Length=247, Percent_Identity=29.5546558704453, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI19920940, Length=244, Percent_Identity=28.6885245901639, Blast_Score=110, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006357
- InterPro:   IPR023215 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 29089; Mature: 28958

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIGGVLFDIDGVLVTSWRPIDGAAEALRVLSDHQIARSYLTNTTTKTRRQIADLLVDAG
CCCCCEEEEECCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
MAVTADEVITAAVLTAEYVRDRYPGARCFLVNSGRIGEDMPGVDLVYAGEFGPDHVPETP
CEEEHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEEEEECCCCCCCCCCCC
DVVLLGGAGPEYDHLTLSWVYDWMARGVPVVAMHRSTSWNTADGLRIDTGMYLIGMEETS
CEEEECCCCCCCCCEEHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEECCEEEEEECCCC
GRKATAVGKPAPEGFLAAAGRLGVDPEEMYIVGDDLNNDVLAGQVVGMTGVLVRTGKFRQ
CCEEEECCCCCCCCHHHHCCCCCCCCCCEEEECCCCCCCEEEEEEECCEEEEEECCCCCH
DTLDRWAADEFAMQPNHVIDSVADLPGLLGL
HHHHHHHHHHHCCCCHHHHHHHHHCCHHCCC
>Mature Secondary Structure 
AIGGVLFDIDGVLVTSWRPIDGAAEALRVLSDHQIARSYLTNTTTKTRRQIADLLVDAG
CCCCEEEEECCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
MAVTADEVITAAVLTAEYVRDRYPGARCFLVNSGRIGEDMPGVDLVYAGEFGPDHVPETP
CEEEHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEEEEECCCCCCCCCCCC
DVVLLGGAGPEYDHLTLSWVYDWMARGVPVVAMHRSTSWNTADGLRIDTGMYLIGMEETS
CEEEECCCCCCCCCEEHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEECCEEEEEECCCC
GRKATAVGKPAPEGFLAAAGRLGVDPEEMYIVGDDLNNDVLAGQVVGMTGVLVRTGKFRQ
CCEEEECCCCCCCCHHHHCCCCCCCCCCEEEECCCCCCCEEEEEEECCEEEEEECCCCCH
DTLDRWAADEFAMQPNHVIDSVADLPGLLGL
HHHHHHHHHHHCCCCHHHHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]