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The map label for this gene is nreC [H]

Identifier: 108797570

GI number: 108797570

Start: 649981

End: 650628

Strand: Direct

Name: nreC [H]

Synonym: Mmcs_0590

Alternate gene names: 108797570

Gene position: 649981-650628 (Clockwise)

Preceding gene: 108797569

Following gene: 108797577

Centisome position: 11.39

GC content: 69.14

Gene sequence:

>648_bases
ATGCCGGCGCGGATCCTGCTCGCCGACGACCACGCGCTGGTGCGCAGCGGGTTGCGGCTGATCATCGACGCCGAACCCGA
CCTGCAGGTGGTCGCCGAGGCGGCCGACGGGCACGAGGCGCTCGAAGCGCTCGAGCGGACCCCCACCGATCTGGCGATCC
TCGACATCGCGATGCCACGGATGACGGGTCTGCAGGCCGCCCGCGAGATCAGCCGCATGCATCCGCACGTGCGGATCCTG
ATCCTGTCTATGCACGACAACGAGCAGTACTTCTTCGAGGCGCTCAAGGCCGGGGCGTCGGGCTACGTGCTCAAATCTGT
CGCCGACCGCGATCTGCTCGCGGCGTGCCGCGCGACGCTGCGCGGTGAACCGTTCCTGTACGCAGGTGCGGTGACGGCGC
TGATCCGCGACTATCTGCACCGCGCCCGCAGCGGCGACGAACTGCCCGACACCATCCTCACCCCGCGGGAGGAGGAGGTG
CTCAAGCTGGTCGCCGAGGGCTACTCGACGCGGGAGATCGCGGCGACGCTGAGCATCAGCGCCAAGACCGTCGACCGGCA
CCGGGCGAACATCCTCGCCAAGCTGGGTCTGCGGGATCGGTTGGCGCTCACCCGATACGCCATCCGGGCGGGACTGATCG
AGCCGTGA

Upstream 100 bases:

>100_bases
AGCGGGCGCTGTTGGTCAACGCGACGCTGACGATCGCGTCTCCACCGGGTGAGGGCACCGAGGTTCGGTTGACCATCCCG
TACCGCGACGGGAGCCGGTG

Downstream 100 bases:

>100_bases
GCCGCCCGCACGGTGAACCGCCCACGTAGCGCACCGGCAGTGCGTGGCCGAGCACCCCGATGCCTGCGCCGAGGATCGGC
CAGATCGGCCAGAAGTACCA

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 215; Mature: 214

Protein sequence:

>215_residues
MPARILLADDHALVRSGLRLIIDAEPDLQVVAEAADGHEALEALERTPTDLAILDIAMPRMTGLQAAREISRMHPHVRIL
ILSMHDNEQYFFEALKAGASGYVLKSVADRDLLAACRATLRGEPFLYAGAVTALIRDYLHRARSGDELPDTILTPREEEV
LKLVAEGYSTREIAATLSISAKTVDRHRANILAKLGLRDRLALTRYAIRAGLIEP

Sequences:

>Translated_215_residues
MPARILLADDHALVRSGLRLIIDAEPDLQVVAEAADGHEALEALERTPTDLAILDIAMPRMTGLQAAREISRMHPHVRIL
ILSMHDNEQYFFEALKAGASGYVLKSVADRDLLAACRATLRGEPFLYAGAVTALIRDYLHRARSGDELPDTILTPREEEV
LKLVAEGYSTREIAATLSISAKTVDRHRANILAKLGLRDRLALTRYAIRAGLIEP
>Mature_214_residues
PARILLADDHALVRSGLRLIIDAEPDLQVVAEAADGHEALEALERTPTDLAILDIAMPRMTGLQAAREISRMHPHVRILI
LSMHDNEQYFFEALKAGASGYVLKSVADRDLLAACRATLRGEPFLYAGAVTALIRDYLHRARSGDELPDTILTPREEEVL
KLVAEGYSTREIAATLSISAKTVDRHRANILAKLGLRDRLALTRYAIRAGLIEP

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=209, Percent_Identity=30.622009569378, Blast_Score=121, Evalue=3e-29,
Organism=Escherichia coli, GI1788521, Length=203, Percent_Identity=35.9605911330049, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1790102, Length=201, Percent_Identity=37.3134328358209, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1787473, Length=186, Percent_Identity=37.6344086021505, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1786747, Length=207, Percent_Identity=29.951690821256, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1788546, Length=206, Percent_Identity=31.0679611650485, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1788712, Length=210, Percent_Identity=23.8095238095238, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI87082052, Length=120, Percent_Identity=30, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23693; Mature: 23562

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPARILLADDHALVRSGLRLIIDAEPDLQVVAEAADGHEALEALERTPTDLAILDIAMPR
CCCEEEEECCHHHHHCCCEEEEECCCCHHHHHHHCCCHHHHHHHHCCCCCEEHHHHHHHH
MTGLQAAREISRMHPHVRILILSMHDNEQYFFEALKAGASGYVLKSVADRDLLAACRATL
HHHHHHHHHHHHHCCCEEEEEEEEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
RGEPFLYAGAVTALIRDYLHRARSGDELPDTILTPREEEVLKLVAEGYSTREIAATLSIS
CCCCEEHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCHHHHHHHHHCCCCHHHHHHHHHHH
AKTVDRHRANILAKLGLRDRLALTRYAIRAGLIEP
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PARILLADDHALVRSGLRLIIDAEPDLQVVAEAADGHEALEALERTPTDLAILDIAMPR
CCEEEEECCHHHHHCCCEEEEECCCCHHHHHHHCCCHHHHHHHHCCCCCEEHHHHHHHH
MTGLQAAREISRMHPHVRILILSMHDNEQYFFEALKAGASGYVLKSVADRDLLAACRATL
HHHHHHHHHHHHHCCCEEEEEEEEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
RGEPFLYAGAVTALIRDYLHRARSGDELPDTILTPREEEVLKLVAEGYSTREIAATLSIS
CCCCEEHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCHHHHHHHHHCCCCHHHHHHHHHHH
AKTVDRHRANILAKLGLRDRLALTRYAIRAGLIEP
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA