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The map label for this gene is nreB [H]

Identifier: 108797569

GI number: 108797569

Start: 648884

End: 649981

Strand: Direct

Name: nreB [H]

Synonym: Mmcs_0589

Alternate gene names: 108797569

Gene position: 648884-649981 (Clockwise)

Preceding gene: 108797555

Following gene: 108797570

Centisome position: 11.37

GC content: 69.31

Gene sequence:

>1098_bases
TTGGTCCACCTCCATGTTCGGCAGGAGACGCGAGGGCCACCATCGGGGCTGACACCCATTTCCGGGGGGCGGTGCCGTGT
ATGGACATCCTCAGGCCGGGACGCCACGCTGGTGGGTATGAATCGGGCGCGCACCCCCGCGGCCGCACTGTTTCGCCGGG
TCTTCTTGATCAACGGCCTCATCTTCACGCTCGGCACACTCGTCCTCGCCGTGTCACCGGCCTCGGTGTCGTCACGCATC
CGGCTCACCGAGATCCCGGTCCTGGTCGTCGGTTTGGCGGTCATTCTGAGCGCCAACGCGTTGCTGCTGCGGTCCAGCCT
GGCCCCGCTCGATCGGCTGACCGCGTCCATGCGACGGGTCGACCCGCCGCGGCGCAGTGACCGTGTCGACGATCGGGGCA
GCGGTGATCTGCACCATCTGATCGAATCGTTCAACGCGATGCTCGACCGGTTGGAGACCGAGCGGACCACGGCCAGCGCA
TCGGCGCTCGCCGCGCAGGAGAACGAACGGCAGCGCATCGCGCGCGAACTGCACGACGAGATCGGGCAGACGTTGACCGT
CGCCCTGCTCACGCTCAAACGTGCCGTGGACCGCGCGCCGGCGGAGATCCGCGGCGAGTTGGAGGAGACCCAGGAGACGG
TGCGGGCCAGCCTCGATGAGGTGCGCGGCATCGCCCGCCGGCTGCGACCGGACGCGCTCGAGGATCTGGGACTGCAGAGC
GCGCTCAATGCGCTGTGCAATGAATTCGCCCAGGCGACCGGGCTTCCGGTCGTCAAACACATCGCCCTGCCTGCCGCGCG
GCTGGCTCCCGACGTCGAGCTGGTCTGCTACCGCATCGCCCAGGAGTCGCTCACCAACGTCGCGCGCCACGCCGACGCCC
GCAAGGTCTGGGTCGACCTGCACGTCGCCGACGATCAGGTGACGTTGCGGATCGCCGACGACGGGGCGGGCGGTGCGGGT
GACGCGGGGGAGGGCGCCGGCATCAGCGGTATGCGGGAGCGGGCGCTGTTGGTCAACGCGACGCTGACGATCGCGTCTCC
ACCGGGTGAGGGCACCGAGGTTCGGTTGACCATCCCGTACCGCGACGGGAGCCGGTGA

Upstream 100 bases:

>100_bases
TGACCAGTACGCACAGCCGGCCACCGGCCCGGGTGACGATGTGGTGCAGCATCCCGCCGCCGGGCACCGTCGTCCGATCG
ATACGCATCGCAGCTCCTTA

Downstream 100 bases:

>100_bases
TGCCGGCGCGGATCCTGCTCGCCGACGACCACGCGCTGGTGCGCAGCGGGTTGCGGCTGATCATCGACGCCGAACCCGAC
CTGCAGGTGGTCGCCGAGGC

Product: putative signal transduction histidine kinase

Products: NA

Alternate protein names: Nitrogen regulation protein B [H]

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MVHLHVRQETRGPPSGLTPISGGRCRVWTSSGRDATLVGMNRARTPAAALFRRVFLINGLIFTLGTLVLAVSPASVSSRI
RLTEIPVLVVGLAVILSANALLLRSSLAPLDRLTASMRRVDPPRRSDRVDDRGSGDLHHLIESFNAMLDRLETERTTASA
SALAAQENERQRIARELHDEIGQTLTVALLTLKRAVDRAPAEIRGELEETQETVRASLDEVRGIARRLRPDALEDLGLQS
ALNALCNEFAQATGLPVVKHIALPAARLAPDVELVCYRIAQESLTNVARHADARKVWVDLHVADDQVTLRIADDGAGGAG
DAGEGAGISGMRERALLVNATLTIASPPGEGTEVRLTIPYRDGSR

Sequences:

>Translated_365_residues
MVHLHVRQETRGPPSGLTPISGGRCRVWTSSGRDATLVGMNRARTPAAALFRRVFLINGLIFTLGTLVLAVSPASVSSRI
RLTEIPVLVVGLAVILSANALLLRSSLAPLDRLTASMRRVDPPRRSDRVDDRGSGDLHHLIESFNAMLDRLETERTTASA
SALAAQENERQRIARELHDEIGQTLTVALLTLKRAVDRAPAEIRGELEETQETVRASLDEVRGIARRLRPDALEDLGLQS
ALNALCNEFAQATGLPVVKHIALPAARLAPDVELVCYRIAQESLTNVARHADARKVWVDLHVADDQVTLRIADDGAGGAG
DAGEGAGISGMRERALLVNATLTIASPPGEGTEVRLTIPYRDGSR
>Mature_365_residues
MVHLHVRQETRGPPSGLTPISGGRCRVWTSSGRDATLVGMNRARTPAAALFRRVFLINGLIFTLGTLVLAVSPASVSSRI
RLTEIPVLVVGLAVILSANALLLRSSLAPLDRLTASMRRVDPPRRSDRVDDRGSGDLHHLIESFNAMLDRLETERTTASA
SALAAQENERQRIARELHDEIGQTLTVALLTLKRAVDRAPAEIRGELEETQETVRASLDEVRGIARRLRPDALEDLGLQS
ALNALCNEFAQATGLPVVKHIALPAARLAPDVELVCYRIAQESLTNVARHADARKVWVDLHVADDQVTLRIADDGAGGAG
DAGEGAGISGMRERALLVNATLTIASPPGEGTEVRLTIPYRDGSR

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxyg

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI87082311, Length=206, Percent_Identity=34.9514563106796, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787474, Length=200, Percent_Identity=33, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788812, Length=231, Percent_Identity=29.004329004329, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR017203 [H]

Pfam domain/function: PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 39333; Mature: 39333

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: PS50885 HAMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVHLHVRQETRGPPSGLTPISGGRCRVWTSSGRDATLVGMNRARTPAAALFRRVFLINGL
CEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHH
IFTLGTLVLAVSPASVSSRIRLTEIPVLVVGLAVILSANALLLRSSLAPLDRLTASMRRV
HHHHHHHHHHCCCCHHHCCEEHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHC
DPPRRSDRVDDRGSGDLHHLIESFNAMLDRLETERTTASASALAAQENERQRIARELHDE
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGQTLTVALLTLKRAVDRAPAEIRGELEETQETVRASLDEVRGIARRLRPDALEDLGLQS
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHH
ALNALCNEFAQATGLPVVKHIALPAARLAPDVELVCYRIAQESLTNVARHADARKVWVDL
HHHHHHHHHHHHCCCHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEE
HVADDQVTLRIADDGAGGAGDAGEGAGISGMRERALLVNATLTIASPPGEGTEVRLTIPY
EEECCEEEEEEECCCCCCCCCCCCCCCCCHHHHCEEEEEEEEEEECCCCCCCEEEEEEEC
RDGSR
CCCCC
>Mature Secondary Structure
MVHLHVRQETRGPPSGLTPISGGRCRVWTSSGRDATLVGMNRARTPAAALFRRVFLINGL
CEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHH
IFTLGTLVLAVSPASVSSRIRLTEIPVLVVGLAVILSANALLLRSSLAPLDRLTASMRRV
HHHHHHHHHHCCCCHHHCCEEHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHC
DPPRRSDRVDDRGSGDLHHLIESFNAMLDRLETERTTASASALAAQENERQRIARELHDE
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGQTLTVALLTLKRAVDRAPAEIRGELEETQETVRASLDEVRGIARRLRPDALEDLGLQS
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHH
ALNALCNEFAQATGLPVVKHIALPAARLAPDVELVCYRIAQESLTNVARHADARKVWVDL
HHHHHHHHHHHHCCCHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEE
HVADDQVTLRIADDGAGGAGDAGEGAGISGMRERALLVNATLTIASPPGEGTEVRLTIPY
EEECCEEEEEEECCCCCCCCCCCCCCCCCHHHHCEEEEEEEEEEECCCCCCCEEEEEEEC
RDGSR
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12426351 [H]