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The map label for this gene is gbsB [H]

Identifier: 108797490

GI number: 108797490

Start: 564846

End: 566051

Strand: Direct

Name: gbsB [H]

Synonym: Mmcs_0510

Alternate gene names: 108797490

Gene position: 564846-566051 (Clockwise)

Preceding gene: 108797489

Following gene: 108797491

Centisome position: 9.9

GC content: 71.39

Gene sequence:

>1206_bases
GTGACAATCGACAACATCTCGACCATCGCGCCGTTCGGCAACCACCTGCCGGTGCGCATCACCTTCGGCGAGGGCAGCGC
TCACCGCCTGCCCGACCTGCTCCGCGACGCGGGTGCGCAGCGCGTGCTGGTGCTGACCGATCAGGGCATCGAGCACCACA
ACCCGGCGGTCGCGGCTGTCCTGACGACCCTGTCCACCTCGGGCCTGACGGTCAGCCGACTGGACAAGGCCCCCGGTGAA
CCCACGATCGAGATGGTCGACGCCGCCACCGCGAGGATGACCTCCGAATCGGTCGACGCGATCGTCGCCCTCGGCGGCGG
CTCGGTGATCGACACCGCCAAGGCCGCCCGGTTGTGCCACCAGCAGGGCCTGACCTTCGGCGAGTTCCTCGACTCCGCGC
GCACCTATCCGGCTCCCGCGGTCCCGCTGATCGCCGTGCCGACCACGGCGGGTACCGGATCGGAGGTGTCCGGCGGTGCG
GTGGTGTCCGATCCCCAGGCCGGGCGCAAGGCCGGCATCGCCCACCCGAACATGCGGGCCCAGTACGCCGTGGTCGATCC
CGTGCTGACGTGGAGCATGCCGCCGGTGATGACCGCCAACACCGGTATCGACGCGCTCGCACAGGCGATGGCCGCGGTCA
TCGCCAAGGTGCGCACCCCGATCGGGGATGCCATCGCCCTGGAAGCCGTACGCCTGATGGGCCATTCGCTGCCCGCCGCC
TACCGCGACGGCGCCGATGCCGCCGCCCGTGCCGGTATGGCCTGCGGCAGCATGATGGCCGGGCTGGCGATGAACATCTC
CGACTGCGCGGCCGAACACTCGCTGGGGCAGGCCATCGGCGGCCTCTCCGGCGCCCCGCACGGCCTGACCATCGGCCTGG
TGTTGGCCGAGACGCTGGAACGGGAGCGCCACCACGTGCCCGACCGGATGGAGCGCATCGCCGACGCGTGGGGACTGCCC
GCCGACGGGACCGCGGACGGTAGCCGACTGGTCGGTGCGGTCCGCCGACTCCTGAGTGATCTGCAGTTCCCGGTGCTGAG
TGATCTCGGCCTCGGCGCCGAGCATCTGGACCGCCTCACCGACCTGGCCCTGTCGGACTACTTCATCACCATGGCCCCGC
AACCGTGGGACCGCGCCGAGGTGCACCAGGCGTTCGCCCGCGCGCTGGCCACCCGTGACCGCGGCCTCGTCACGGCCGCA
GGTTAG

Upstream 100 bases:

>100_bases
TTGATCTCGGCCGCAACGGCGCCGCTGTTCAACACCTCGACGCTGCCGGTGCAACCGTGATCCAGACACCATCCCTCTCG
ACCACATTTGTTGGAGTGCA

Downstream 100 bases:

>100_bases
GAAAACCATGTCCGCCCAGCAGGATTCGCCCGACCGGTTCGACGTCGTGATCGTCGGTGCCGGCTTCGCCGGCCTGTACA
TGCTGCACCGCGTCCGCGCG

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MTIDNISTIAPFGNHLPVRITFGEGSAHRLPDLLRDAGAQRVLVLTDQGIEHHNPAVAAVLTTLSTSGLTVSRLDKAPGE
PTIEMVDAATARMTSESVDAIVALGGGSVIDTAKAARLCHQQGLTFGEFLDSARTYPAPAVPLIAVPTTAGTGSEVSGGA
VVSDPQAGRKAGIAHPNMRAQYAVVDPVLTWSMPPVMTANTGIDALAQAMAAVIAKVRTPIGDAIALEAVRLMGHSLPAA
YRDGADAAARAGMACGSMMAGLAMNISDCAAEHSLGQAIGGLSGAPHGLTIGLVLAETLERERHHVPDRMERIADAWGLP
ADGTADGSRLVGAVRRLLSDLQFPVLSDLGLGAEHLDRLTDLALSDYFITMAPQPWDRAEVHQAFARALATRDRGLVTAA
G

Sequences:

>Translated_401_residues
MTIDNISTIAPFGNHLPVRITFGEGSAHRLPDLLRDAGAQRVLVLTDQGIEHHNPAVAAVLTTLSTSGLTVSRLDKAPGE
PTIEMVDAATARMTSESVDAIVALGGGSVIDTAKAARLCHQQGLTFGEFLDSARTYPAPAVPLIAVPTTAGTGSEVSGGA
VVSDPQAGRKAGIAHPNMRAQYAVVDPVLTWSMPPVMTANTGIDALAQAMAAVIAKVRTPIGDAIALEAVRLMGHSLPAA
YRDGADAAARAGMACGSMMAGLAMNISDCAAEHSLGQAIGGLSGAPHGLTIGLVLAETLERERHHVPDRMERIADAWGLP
ADGTADGSRLVGAVRRLLSDLQFPVLSDLGLGAEHLDRLTDLALSDYFITMAPQPWDRAEVHQAFARALATRDRGLVTAA
G
>Mature_400_residues
TIDNISTIAPFGNHLPVRITFGEGSAHRLPDLLRDAGAQRVLVLTDQGIEHHNPAVAAVLTTLSTSGLTVSRLDKAPGEP
TIEMVDAATARMTSESVDAIVALGGGSVIDTAKAARLCHQQGLTFGEFLDSARTYPAPAVPLIAVPTTAGTGSEVSGGAV
VSDPQAGRKAGIAHPNMRAQYAVVDPVLTWSMPPVMTANTGIDALAQAMAAVIAKVRTPIGDAIALEAVRLMGHSLPAAY
RDGADAAARAGMACGSMMAGLAMNISDCAAEHSLGQAIGGLSGAPHGLTIGLVLAETLERERHHVPDRMERIADAWGLPA
DGTADGSRLVGAVRRLLSDLQFPVLSDLGLGAEHLDRLTDLALSDYFITMAPQPWDRAEVHQAFARALATRDRGLVTAAG

Specific function: Essential for the utilization of choline as a precursor [H]

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=352, Percent_Identity=28.125, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI87082107, Length=386, Percent_Identity=31.0880829015544, Blast_Score=151, Evalue=7e-38,
Organism=Escherichia coli, GI48994951, Length=339, Percent_Identity=30.3834808259587, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1787493, Length=355, Percent_Identity=29.2957746478873, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1789163, Length=351, Percent_Identity=28.2051282051282, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1789386, Length=352, Percent_Identity=26.9886363636364, Blast_Score=96, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17537053, Length=419, Percent_Identity=27.4463007159904, Blast_Score=122, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6321181, Length=388, Percent_Identity=29.639175257732, Blast_Score=163, Evalue=5e-41,
Organism=Drosophila melanogaster, GI24657991, Length=414, Percent_Identity=27.0531400966184, Blast_Score=93, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 41533; Mature: 41402

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIDNISTIAPFGNHLPVRITFGEGSAHRLPDLLRDAGAQRVLVLTDQGIEHHNPAVAAV
CCCCCCCHHCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHH
LTTLSTSGLTVSRLDKAPGEPTIEMVDAATARMTSESVDAIVALGGGSVIDTAKAARLCH
HHHHCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHH
QQGLTFGEFLDSARTYPAPAVPLIAVPTTAGTGSEVSGGAVVSDPQAGRKAGIAHPNMRA
HHCCCHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCC
QYAVVDPVLTWSMPPVMTANTGIDALAQAMAAVIAKVRTPIGDAIALEAVRLMGHSLPAA
EEEEECHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHH
YRDGADAAARAGMACGSMMAGLAMNISDCAAEHSLGQAIGGLSGAPHGLTIGLVLAETLE
HCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
RERHHVPDRMERIADAWGLPADGTADGSRLVGAVRRLLSDLQFPVLSDLGLGAEHLDRLT
HHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHH
DLALSDYFITMAPQPWDRAEVHQAFARALATRDRGLVTAAG
HHHHHCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEECC
>Mature Secondary Structure 
TIDNISTIAPFGNHLPVRITFGEGSAHRLPDLLRDAGAQRVLVLTDQGIEHHNPAVAAV
CCCCCCHHCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHH
LTTLSTSGLTVSRLDKAPGEPTIEMVDAATARMTSESVDAIVALGGGSVIDTAKAARLCH
HHHHCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHH
QQGLTFGEFLDSARTYPAPAVPLIAVPTTAGTGSEVSGGAVVSDPQAGRKAGIAHPNMRA
HHCCCHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCC
QYAVVDPVLTWSMPPVMTANTGIDALAQAMAAVIAKVRTPIGDAIALEAVRLMGHSLPAA
EEEEECHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHH
YRDGADAAARAGMACGSMMAGLAMNISDCAAEHSLGQAIGGLSGAPHGLTIGLVLAETLE
HCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
RERHHVPDRMERIADAWGLPADGTADGSRLVGAVRRLLSDLQFPVLSDLGLGAEHLDRLT
HHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHH
DLALSDYFITMAPQPWDRAEVHQAFARALATRDRGLVTAAG
HHHHHCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8752328; 9384377 [H]