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The map label for this gene is yajO [H]

Identifier: 108797014

GI number: 108797014

Start: 43100

End: 44119

Strand: Reverse

Name: yajO [H]

Synonym: Mmcs_0033

Alternate gene names: 108797014

Gene position: 44119-43100 (Counterclockwise)

Preceding gene: 108797017

Following gene: 108797006

Centisome position: 0.77

GC content: 63.33

Gene sequence:

>1020_bases
ATGAGATACCGAACCCTCGGACGGACTGGAATACAGGTGAGCGCCATCGGCCTCGGCGCGATGATGTTCGCCACCCGCAT
GGGCAACTCGAAACAGGAATCAGTCGATGTCATTCATCGCGCGCTCGATGCTGGCATCAACCTGATCGACACCGCCGACG
CTTATGAAGACTCCGAAGACATCGTCGGTCATGCGCTCAAGGGCCGCCGCGACGACGTCGTCCTGGCCACCAAGTTCGGT
AGGCCCGTGGACGACAACCCCAACCATCGAGGCGCGTCGCGCCGCTGGATCGTTGCTGCAGTGGAGAACTCGCTACGCCG
ACTGCAGACCGACTACATCGACATCTACCAACTGCATCGCTCCGATCCCGACACCGACCTCGAAGAAACCCTGTCGGCTT
TGACAGACCTGGTCCGCAGCGGGAAGATCCGTGCCTTCGGAACCTCCACCCTTCCTGCCTCAAATCTTGTGCAGGCGCAG
TGGATTGCCGAGCGGCACGGATACGAGCGACCGCACACTGAGCAACCGCCGTACTCAATCCTCAATCGCGGCATTGAACG
CGAAGTGCTACCTATAGCCCAGCAGTACGGCCTAGGTGTCCTCGTATGGGGACCACTGGGGCAAGGCATGCTCACCGGGC
GTGTGCGTCGCGGTCACGACAACGACGTCATTCGCGCCCAGCTGCTCTCCTCGTTTCACGACCAACGCCGTCTAGATGCA
GTCGAGCGCCTGATTCCCGTTGCCGCACAGGCCGGCCTGAGCATGCCGCACCTGGCTATGGCGTTCACCATCGCCCATCC
CGGCGTGACGGGCGCGCTGCTCGGCGCGCGGACCATGAGCCACCTTGATGATCTACTCACCGGCGCCGACACCGTCCTCG
GCGACGACGTTCTCGACGAGATAGACGACATCGTGCCCCCAGGCACCGACGCTGGGCCCCTGGACCAAGACCACACCCCG
CCTGCCATACAAAAGGCCGCACTTCGTCGCCGCCCGCTCGCTGAGCGCGCGGCCGCATAG

Upstream 100 bases:

>100_bases
CGGGTCGACCTGCCATGGCCTCTAGCTTAATGGAACATCGTTCCGTATATTACCGGAAAGAGGTTCCAGATACTGTTCGA
CCTTGAGACGGAGGCACACG

Downstream 100 bases:

>100_bases
TCTCGGACCCCCACCCCCACCAAACACAGAGGTCACGAACCCGTATGAGTTCGTGACCTCTGCGCCTGCGGTTCATGAAC
CGCTCGCTGTGTGCGGTACG

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MRYRTLGRTGIQVSAIGLGAMMFATRMGNSKQESVDVIHRALDAGINLIDTADAYEDSEDIVGHALKGRRDDVVLATKFG
RPVDDNPNHRGASRRWIVAAVENSLRRLQTDYIDIYQLHRSDPDTDLEETLSALTDLVRSGKIRAFGTSTLPASNLVQAQ
WIAERHGYERPHTEQPPYSILNRGIEREVLPIAQQYGLGVLVWGPLGQGMLTGRVRRGHDNDVIRAQLLSSFHDQRRLDA
VERLIPVAAQAGLSMPHLAMAFTIAHPGVTGALLGARTMSHLDDLLTGADTVLGDDVLDEIDDIVPPGTDAGPLDQDHTP
PAIQKAALRRRPLAERAAA

Sequences:

>Translated_339_residues
MRYRTLGRTGIQVSAIGLGAMMFATRMGNSKQESVDVIHRALDAGINLIDTADAYEDSEDIVGHALKGRRDDVVLATKFG
RPVDDNPNHRGASRRWIVAAVENSLRRLQTDYIDIYQLHRSDPDTDLEETLSALTDLVRSGKIRAFGTSTLPASNLVQAQ
WIAERHGYERPHTEQPPYSILNRGIEREVLPIAQQYGLGVLVWGPLGQGMLTGRVRRGHDNDVIRAQLLSSFHDQRRLDA
VERLIPVAAQAGLSMPHLAMAFTIAHPGVTGALLGARTMSHLDDLLTGADTVLGDDVLDEIDDIVPPGTDAGPLDQDHTP
PAIQKAALRRRPLAERAAA
>Mature_339_residues
MRYRTLGRTGIQVSAIGLGAMMFATRMGNSKQESVDVIHRALDAGINLIDTADAYEDSEDIVGHALKGRRDDVVLATKFG
RPVDDNPNHRGASRRWIVAAVENSLRRLQTDYIDIYQLHRSDPDTDLEETLSALTDLVRSGKIRAFGTSTLPASNLVQAQ
WIAERHGYERPHTEQPPYSILNRGIEREVLPIAQQYGLGVLVWGPLGQGMLTGRVRRGHDNDVIRAQLLSSFHDQRRLDA
VERLIPVAAQAGLSMPHLAMAFTIAHPGVTGALLGARTMSHLDDLLTGADTVLGDDVLDEIDDIVPPGTDAGPLDQDHTP
PAIQKAALRRRPLAERAAA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=326, Percent_Identity=30.9815950920245, Blast_Score=148, Evalue=7e-36,
Organism=Homo sapiens, GI27436962, Length=326, Percent_Identity=30.9815950920245, Blast_Score=146, Evalue=2e-35,
Organism=Homo sapiens, GI27436969, Length=328, Percent_Identity=30.4878048780488, Blast_Score=144, Evalue=9e-35,
Organism=Homo sapiens, GI4504825, Length=326, Percent_Identity=29.4478527607362, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI27436966, Length=326, Percent_Identity=30.6748466257669, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI27436971, Length=326, Percent_Identity=31.2883435582822, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI223718702, Length=315, Percent_Identity=28.5714285714286, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI41327764, Length=292, Percent_Identity=28.0821917808219, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI41152114, Length=227, Percent_Identity=25.9911894273128, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI87081735, Length=320, Percent_Identity=37.5, Blast_Score=193, Evalue=1e-50,
Organism=Escherichia coli, GI1789199, Length=339, Percent_Identity=32.1533923303835, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1788070, Length=298, Percent_Identity=34.8993288590604, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1789375, Length=328, Percent_Identity=28.0487804878049, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1788081, Length=318, Percent_Identity=29.559748427673, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI48994888, Length=140, Percent_Identity=31.4285714285714, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI212645785, Length=315, Percent_Identity=28.5714285714286, Blast_Score=85, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6325169, Length=333, Percent_Identity=28.5285285285285, Blast_Score=152, Evalue=9e-38,
Organism=Saccharomyces cerevisiae, GI6323998, Length=326, Percent_Identity=28.8343558282209, Blast_Score=131, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6319958, Length=322, Percent_Identity=28.8819875776398, Blast_Score=129, Evalue=9e-31,
Organism=Saccharomyces cerevisiae, GI6319951, Length=333, Percent_Identity=27.6276276276276, Blast_Score=109, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6322615, Length=248, Percent_Identity=29.0322580645161, Blast_Score=106, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6321052, Length=158, Percent_Identity=34.8101265822785, Blast_Score=76, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24640980, Length=360, Percent_Identity=25.8333333333333, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI45549126, Length=360, Percent_Identity=25.8333333333333, Blast_Score=111, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24646155, Length=339, Percent_Identity=28.6135693215339, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24646159, Length=222, Percent_Identity=31.0810810810811, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37078; Mature: 37078

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYRTLGRTGIQVSAIGLGAMMFATRMGNSKQESVDVIHRALDAGINLIDTADAYEDSED
CCCCCCCCCCCEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEECCCCCCCHHH
IVGHALKGRRDDVVLATKFGRPVDDNPNHRGASRRWIVAAVENSLRRLQTDYIDIYQLHR
HHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHC
SDPDTDLEETLSALTDLVRSGKIRAFGTSTLPASNLVQAQWIAERHGYERPHTEQPPYSI
CCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHH
LNRGIEREVLPIAQQYGLGVLVWGPLGQGMLTGRVRRGHDNDVIRAQLLSSFHDQRRLDA
HHCCCHHHHHHHHHHCCCEEEEECCCCCCHHHCCHHCCCCCHHHHHHHHHHHHHHHHHHH
VERLIPVAAQAGLSMPHLAMAFTIAHPGVTGALLGARTMSHLDDLLTGADTVLGDDVLDE
HHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDDIVPPGTDAGPLDQDHTPPAIQKAALRRRPLAERAAA
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHCC
>Mature Secondary Structure
MRYRTLGRTGIQVSAIGLGAMMFATRMGNSKQESVDVIHRALDAGINLIDTADAYEDSED
CCCCCCCCCCCEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEECCCCCCCHHH
IVGHALKGRRDDVVLATKFGRPVDDNPNHRGASRRWIVAAVENSLRRLQTDYIDIYQLHR
HHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHC
SDPDTDLEETLSALTDLVRSGKIRAFGTSTLPASNLVQAQWIAERHGYERPHTEQPPYSI
CCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHH
LNRGIEREVLPIAQQYGLGVLVWGPLGQGMLTGRVRRGHDNDVIRAQLLSSFHDQRRLDA
HHCCCHHHHHHHHHHCCCEEEEECCCCCCHHHCCHHCCCCCHHHHHHHHHHHHHHHHHHH
VERLIPVAAQAGLSMPHLAMAFTIAHPGVTGALLGARTMSHLDDLLTGADTVLGDDVLDE
HHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDDIVPPGTDAGPLDQDHTPPAIQKAALRRRPLAERAAA
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]