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The map label for this gene is hsdM [C]

Identifier: 108797003

GI number: 108797003

Start: 27053

End: 28540

Strand: Direct

Name: hsdM [C]

Synonym: Mmcs_0022

Alternate gene names: 108797003

Gene position: 27053-28540 (Clockwise)

Preceding gene: 108796995

Following gene: 108797004

Centisome position: 0.47

GC content: 59.74

Gene sequence:

>1488_bases
ATGCGGAGGCAGAAGATTGTTCGTGGGCGAGGCGCCTCGAACCGACAGAACGGAACGTGGTTGAAGACGACTGACCTCGC
CAAAGTGCGCAATACGCTGTGGGCCGCTGCTGACGAGTTGCGAGCAAACTCGAAGTTGACGCCGGTCCAGTATCGCAATC
CGGTACTCGGCTTGGTGTTCCTCGCCTACGCGGAGAACCGTTTCGAGGCCGTCCGCGGTGAGGTCGAGTCGAAGGCGTCC
GCTCGCAACCCCGCGACGCCCGCTGACTATAAGGCCAAGTCCGTGTTGTACGTGCCGGAGGAATCGCGGCTGTCGTACCT
CAACGACCTTCCGGAGGGGGACGACATTGGCAAGGCCGTAGATGACGCGATCAAGGCGATTGAAGCCGCCAATCCCGAAC
TCAAGGACATTCTGCCGCGTGGCTACCAAAAGCTCGAACGGTCTACTCTGATCGAGCTGCTGCGCTTGTTTGCGCCGTTA
CCTACACAGCTCGAAGGTGACGCCTTCGGCTTCATATACGAAGACTTCCTGTCGAATTTCGCCGCGCAAGAAGGCAAGGG
CGGTGGCGAGTACTTCACGCCCTATTCGATCGTCCGGCTTATCGTCGAGATTCTCGAACCGTTTCACGGCCGAGTTTTCG
ACCCCGCTTGCGGATCAGGCGGCATGTTCGTCCAATGCGCGAAATTTGTTGAGCGTCACAATGAATCGGCGAATCGCAAG
CTCTCTATCTTCGGTGCGGAGAAGACCGACGACACCGTGCCGCTGGCGAAGATGAACCTCGCGCTGCACGGGCTCTCTGG
TGACATTCGGCAAGCCAACAGCTACTACGAGGACCCGCACAAGGCGGTCGGCGCCTTCGACTACGTAATGGCAAACCCGC
CCTTCAACGTCGACAAAGTCAAGAAGGGGCAGCTCGCTGGTGACAAGCGCTTCCCCTTCGGCATTCCCAAGCCCGACAAC
GCCAACTACCTGTGGATTCAGCAGTTCTACGCTGCGCTCGGGCCGAAGGGCCGCGCCGGATTCGTCATGGCCAACTCAGC
GGGCGATGCGGGGCATTCGGAGAAGGAAATCCGCAAGCAGATCATCGAATCTGGCGTAGTAGACGTAATGGTCGCGATTA
GTTCCAACTTCTTCTACACCGTGACTCTCCCCGTGACGCTGTGGTTCATGGATAAGGCCAAGGCAGGAACGCAGCGCGAG
GACGCTGTGCTCTTCCTTGATGCCCGGCATACCTACCGGCAGATCGACCGCGCCCACCGCGACTTCACGGCGGAGCAGAT
CGAATTCCTCGCAAATGTCGTGCGTCTTTACCGAGGCGAAGCTGTCGAGACCGTTGCGGGTAGTGACGTACTACTCAAGG
AGCACTTCCCCGACGGCAAGTACATAGACGTCCCTGGGCTCTGCAAGGTCGCGACGCGTTCCGAGATCGAAGACCAGGGG
TGGAGTCTGAACCCCCGGCCGCTACGCCGGCTCCACGGTCGTGGCTGA

Upstream 100 bases:

>100_bases
CCCTTGGCCGAATCAAGTCCGTCGCCATGCGATGATCCGCGAAAAGATGGCTGTTGGCGCCCGTAGTTGTTTCAAATAAG
CGCTGCGGAGTCACCGCCGT

Downstream 100 bases:

>100_bases
GCGGGACGAGGACTTCACAGCGAGACTCGAAGAGATGTATGAGGAATTCACTCGTCTCAGTGACGAGGCAGAGGGTCTCC
GATGCAAGGTCGACGCCGCA

Product: N-6 DNA methylase

Products: NA

Alternate protein names: M.MjaXP [H]

Number of amino acids: Translated: 495; Mature: 495

Protein sequence:

>495_residues
MRRQKIVRGRGASNRQNGTWLKTTDLAKVRNTLWAAADELRANSKLTPVQYRNPVLGLVFLAYAENRFEAVRGEVESKAS
ARNPATPADYKAKSVLYVPEESRLSYLNDLPEGDDIGKAVDDAIKAIEAANPELKDILPRGYQKLERSTLIELLRLFAPL
PTQLEGDAFGFIYEDFLSNFAAQEGKGGGEYFTPYSIVRLIVEILEPFHGRVFDPACGSGGMFVQCAKFVERHNESANRK
LSIFGAEKTDDTVPLAKMNLALHGLSGDIRQANSYYEDPHKAVGAFDYVMANPPFNVDKVKKGQLAGDKRFPFGIPKPDN
ANYLWIQQFYAALGPKGRAGFVMANSAGDAGHSEKEIRKQIIESGVVDVMVAISSNFFYTVTLPVTLWFMDKAKAGTQRE
DAVLFLDARHTYRQIDRAHRDFTAEQIEFLANVVRLYRGEAVETVAGSDVLLKEHFPDGKYIDVPGLCKVATRSEIEDQG
WSLNPRPLRRLHGRG

Sequences:

>Translated_495_residues
MRRQKIVRGRGASNRQNGTWLKTTDLAKVRNTLWAAADELRANSKLTPVQYRNPVLGLVFLAYAENRFEAVRGEVESKAS
ARNPATPADYKAKSVLYVPEESRLSYLNDLPEGDDIGKAVDDAIKAIEAANPELKDILPRGYQKLERSTLIELLRLFAPL
PTQLEGDAFGFIYEDFLSNFAAQEGKGGGEYFTPYSIVRLIVEILEPFHGRVFDPACGSGGMFVQCAKFVERHNESANRK
LSIFGAEKTDDTVPLAKMNLALHGLSGDIRQANSYYEDPHKAVGAFDYVMANPPFNVDKVKKGQLAGDKRFPFGIPKPDN
ANYLWIQQFYAALGPKGRAGFVMANSAGDAGHSEKEIRKQIIESGVVDVMVAISSNFFYTVTLPVTLWFMDKAKAGTQRE
DAVLFLDARHTYRQIDRAHRDFTAEQIEFLANVVRLYRGEAVETVAGSDVLLKEHFPDGKYIDVPGLCKVATRSEIEDQG
WSLNPRPLRRLHGRG
>Mature_495_residues
MRRQKIVRGRGASNRQNGTWLKTTDLAKVRNTLWAAADELRANSKLTPVQYRNPVLGLVFLAYAENRFEAVRGEVESKAS
ARNPATPADYKAKSVLYVPEESRLSYLNDLPEGDDIGKAVDDAIKAIEAANPELKDILPRGYQKLERSTLIELLRLFAPL
PTQLEGDAFGFIYEDFLSNFAAQEGKGGGEYFTPYSIVRLIVEILEPFHGRVFDPACGSGGMFVQCAKFVERHNESANRK
LSIFGAEKTDDTVPLAKMNLALHGLSGDIRQANSYYEDPHKAVGAFDYVMANPPFNVDKVKKGQLAGDKRFPFGIPKPDN
ANYLWIQQFYAALGPKGRAGFVMANSAGDAGHSEKEIRKQIIESGVVDVMVAISSNFFYTVTLPVTLWFMDKAKAGTQRE
DAVLFLDARHTYRQIDRAHRDFTAEQIEFLANVVRLYRGEAVETVAGSDVLLKEHFPDGKYIDVPGLCKVATRSEIEDQG
WSLNPRPLRRLHGRG

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790808, Length=252, Percent_Identity=24.6031746031746, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022749
- InterPro:   IPR003356
- InterPro:   IPR002052
- InterPro:   IPR002296 [H]

Pfam domain/function: PF12161 HsdM_N; PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 55184; Mature: 55184

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRQKIVRGRGASNRQNGTWLKTTDLAKVRNTLWAAADELRANSKLTPVQYRNPVLGLVF
CCCCHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHH
LAYAENRFEAVRGEVESKASARNPATPADYKAKSVLYVPEESRLSYLNDLPEGDDIGKAV
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCHHHHHHHHCCCCCCHHHHHH
DDAIKAIEAANPELKDILPRGYQKLERSTLIELLRLFAPLPTQLEGDAFGFIYEDFLSNF
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AAQEGKGGGEYFTPYSIVRLIVEILEPFHGRVFDPACGSGGMFVQCAKFVERHNESANRK
HHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHHHCCCCCCE
LSIFGAEKTDDTVPLAKMNLALHGLSGDIRQANSYYEDPHKAVGAFDYVMANPPFNVDKV
EEEEECCCCCCCCCHHHHHEEEECCCCCHHHHHHHHCCHHHHHCHHHHEECCCCCCCCCC
KKGQLAGDKRFPFGIPKPDNANYLWIQQFYAALGPKGRAGFVMANSAGDAGHSEKEIRKQ
CCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHH
IIESGVVDVMVAISSNFFYTVTLPVTLWFMDKAKAGTQREDAVLFLDARHTYRQIDRAHR
HHHCCHHHHHHEECCCEEEEEEEEEEEEEEHHHCCCCCCCCEEEEEECHHHHHHHHHHHH
DFTAEQIEFLANVVRLYRGEAVETVAGSDVLLKEHFPDGKYIDVPGLCKVATRSEIEDQG
CCCHHHHHHHHHHHHHHCCCHHHHHCCCCEEEEECCCCCCEECCCCCHHHHHHHHHHHCC
WSLNPRPLRRLHGRG
CCCCCHHHHHHCCCC
>Mature Secondary Structure
MRRQKIVRGRGASNRQNGTWLKTTDLAKVRNTLWAAADELRANSKLTPVQYRNPVLGLVF
CCCCHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHH
LAYAENRFEAVRGEVESKASARNPATPADYKAKSVLYVPEESRLSYLNDLPEGDDIGKAV
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCHHHHHHHHCCCCCCHHHHHH
DDAIKAIEAANPELKDILPRGYQKLERSTLIELLRLFAPLPTQLEGDAFGFIYEDFLSNF
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AAQEGKGGGEYFTPYSIVRLIVEILEPFHGRVFDPACGSGGMFVQCAKFVERHNESANRK
HHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHHHCCCCCCE
LSIFGAEKTDDTVPLAKMNLALHGLSGDIRQANSYYEDPHKAVGAFDYVMANPPFNVDKV
EEEEECCCCCCCCCHHHHHEEEECCCCCHHHHHHHHCCHHHHHCHHHHEECCCCCCCCCC
KKGQLAGDKRFPFGIPKPDNANYLWIQQFYAALGPKGRAGFVMANSAGDAGHSEKEIRKQ
CCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHH
IIESGVVDVMVAISSNFFYTVTLPVTLWFMDKAKAGTQREDAVLFLDARHTYRQIDRAHR
HHHCCHHHHHHEECCCEEEEEEEEEEEEEEHHHCCCCCCCCEEEEEECHHHHHHHHHHHH
DFTAEQIEFLANVVRLYRGEAVETVAGSDVLLKEHFPDGKYIDVPGLCKVATRSEIEDQG
CCCHHHHHHHHHHHHHHCCCHHHHHCCCCEEEEECCCCCCEECCCCCHHHHHHHHHHHCC
WSLNPRPLRRLHGRG
CCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]