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The map label for this gene is hsdS [H]

Identifier: 108797004

GI number: 108797004

Start: 28661

End: 29896

Strand: Direct

Name: hsdS [H]

Synonym: Mmcs_0023

Alternate gene names: 108797004

Gene position: 28661-29896 (Clockwise)

Preceding gene: 108797003

Following gene: 108797005

Centisome position: 0.5

GC content: 58.01

Gene sequence:

>1236_bases
ATGACGGTGTGGCGGGAGTCTGTGCTCGGAGATCTATGCACGAGAGTGACGGTCGGGCACGTCGGAAAGATGGCCACCGA
GTACGTTCCGGACGGCGTCCCTTTCCTCCGGTCACAAAACGTGCGGCCTTTCGTGATTGACAAGCGCGGCTTGCTCTACA
TCGGTGACGACTTCAACGCAAAGCTGCGCAAATCGGCGCTCACTGCGGGTGACGTCGTTATCGTCCGCACGGGATATCCG
GGAACGGCAGCTGTCGTCCCCGAGGATCTTGATGGATCCAACTGCGCCGATCTTGTTGTCATTACACCGTCAGACGCATT
GAATCCTCACGTGCTTGCAGCGCTCTTCAACTCGGTCTACGGGCAGCACGCGGTCAGTTCGCAATTAGTTGGCTCTGCGC
AACAGCACTTCAACGTTGGCTCGGCCAAGACGATGCGGGTCCGACTGCCCGATCGTGCTGAGCAGGACCACATCGCAGCA
GTCCTCTGTTCGATCAATGACTTGATCGAAAACAACCGACGACGTGTGGAGGTTTTGGAGGGGATGGCGCGGACCATCTA
CCGCGAGTGGTTCGTGAAATTCCGCTACCCAGGCAACGAAGGCGTCCCTCTTGTCGACTCTGCGCTGGGCCCAGCACCGA
AGGGGTGGGAAGTCGCGAATCTATTCGACGCTGCTGACGTCGGCTTTGGGTACTCATTCAAGTCTCCCCGGTTTTCGAAT
TCTGGTCCATTCCAGGTGATTCGGATCCGCGACATCCCAGTCGGCATCTCAAGGACATATACCGATGAAGCAGCAGATCC
GCGCTACGCCGTCTATGACGATGACGTGCTTATAGGTATGGACGGTGACTTCCACATGACGGTCTGGACTGGTGAAGACG
CGTGGCTGAACCAGCGAGTCACCCGCCTTCGCCCGAGGCTCGGGCTGTCCGCGCTTCATCTATTGCTCGCGATCGAGGAG
CAGATCAAAGACTGGAACCGCGCAATTGTTGGCACGACTGTGGCGCATCTAGGTAAGAAGCATCTCCAACTTGTCAACGT
CCTCGTGCCGAATGATGCAGTACGCATAGACGCATCTGTCGTGTTTGCGCCCATCATGGAGGAGCGTCGTGCGCTCATCC
AATCAAGTCGGCGGCTCGCCGCTCTTCGCGACCTCCTGCTTCCGAAGCTGGTCAGCGGACAGATCGACGTTTCCGCACTC
GACTTGGATGCAGTGGTTGGAGAACAGGTGGCGTGA

Upstream 100 bases:

>100_bases
CGAGACTCGAAGAGATGTATGAGGAATTCACTCGTCTCAGTGACGAGGCAGAGGGTCTCCGATGCAAGGTCGACGCCGCA
GTTCAAGGGATTCTCGACGC

Downstream 100 bases:

>100_bases
TGATGGCAAGGGGTCCGGAGTACGACTACGTCGAGAAGCCCAGCATGGAGTTGTTGGCTGAGCTCGGCTGGAACCCGGTC
GATGCTTTCCACGAAATCCT

Product: type I restriction-modification system specificity subunit

Products: NA

Alternate protein names: S.EcoBI; Type I restriction enzyme EcoBI specificity protein; S protein [H]

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MTVWRESVLGDLCTRVTVGHVGKMATEYVPDGVPFLRSQNVRPFVIDKRGLLYIGDDFNAKLRKSALTAGDVVIVRTGYP
GTAAVVPEDLDGSNCADLVVITPSDALNPHVLAALFNSVYGQHAVSSQLVGSAQQHFNVGSAKTMRVRLPDRAEQDHIAA
VLCSINDLIENNRRRVEVLEGMARTIYREWFVKFRYPGNEGVPLVDSALGPAPKGWEVANLFDAADVGFGYSFKSPRFSN
SGPFQVIRIRDIPVGISRTYTDEAADPRYAVYDDDVLIGMDGDFHMTVWTGEDAWLNQRVTRLRPRLGLSALHLLLAIEE
QIKDWNRAIVGTTVAHLGKKHLQLVNVLVPNDAVRIDASVVFAPIMEERRALIQSSRRLAALRDLLLPKLVSGQIDVSAL
DLDAVVGEQVA

Sequences:

>Translated_411_residues
MTVWRESVLGDLCTRVTVGHVGKMATEYVPDGVPFLRSQNVRPFVIDKRGLLYIGDDFNAKLRKSALTAGDVVIVRTGYP
GTAAVVPEDLDGSNCADLVVITPSDALNPHVLAALFNSVYGQHAVSSQLVGSAQQHFNVGSAKTMRVRLPDRAEQDHIAA
VLCSINDLIENNRRRVEVLEGMARTIYREWFVKFRYPGNEGVPLVDSALGPAPKGWEVANLFDAADVGFGYSFKSPRFSN
SGPFQVIRIRDIPVGISRTYTDEAADPRYAVYDDDVLIGMDGDFHMTVWTGEDAWLNQRVTRLRPRLGLSALHLLLAIEE
QIKDWNRAIVGTTVAHLGKKHLQLVNVLVPNDAVRIDASVVFAPIMEERRALIQSSRRLAALRDLLLPKLVSGQIDVSAL
DLDAVVGEQVA
>Mature_410_residues
TVWRESVLGDLCTRVTVGHVGKMATEYVPDGVPFLRSQNVRPFVIDKRGLLYIGDDFNAKLRKSALTAGDVVIVRTGYPG
TAAVVPEDLDGSNCADLVVITPSDALNPHVLAALFNSVYGQHAVSSQLVGSAQQHFNVGSAKTMRVRLPDRAEQDHIAAV
LCSINDLIENNRRRVEVLEGMARTIYREWFVKFRYPGNEGVPLVDSALGPAPKGWEVANLFDAADVGFGYSFKSPRFSNS
GPFQVIRIRDIPVGISRTYTDEAADPRYAVYDDDVLIGMDGDFHMTVWTGEDAWLNQRVTRLRPRLGLSALHLLLAIEEQ
IKDWNRAIVGTTVAHLGKKHLQLVNVLVPNDAVRIDASVVFAPIMEERRALIQSSRRLAALRDLLLPKLVSGQIDVSALD
LDAVVGEQVA

Specific function: The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. In the presence of the R subunit the complex can also act as an endonuclease, binding to

COG id: COG0732

COG function: function code V; Restriction endonuclease S subunits

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I restriction system S methylase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000055 [H]

Pfam domain/function: PF01420 Methylase_S [H]

EC number: NA

Molecular weight: Translated: 45216; Mature: 45085

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVWRESVLGDLCTRVTVGHVGKMATEYVPDGVPFLRSQNVRPFVIDKRGLLYIGDDFNA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCEEEEECCCEEEECCCCCH
KLRKSALTAGDVVIVRTGYPGTAAVVPEDLDGSNCADLVVITPSDALNPHVLAALFNSVY
HHHHHHCCCCCEEEEEECCCCCEEECCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHH
GQHAVSSQLVGSAQQHFNVGSAKTMRVRLPDRAEQDHIAAVLCSINDLIENNRRRVEVLE
HHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHH
GMARTIYREWFVKFRYPGNEGVPLVDSALGPAPKGWEVANLFDAADVGFGYSFKSPRFSN
HHHHHHHHHHEEEEECCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCC
SGPFQVIRIRDIPVGISRTYTDEAADPRYAVYDDDVLIGMDGDFHMTVWTGEDAWLNQRV
CCCEEEEEEEECCCCCCCCCCCCCCCCCEEEECCCEEEECCCCEEEEEECCCCHHHHHHH
TRLRPRLGLSALHLLLAIEEQIKDWNRAIVGTTVAHLGKKHLQLVNVLVPNDAVRIDASV
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEEHHH
VFAPIMEERRALIQSSRRLAALRDLLLPKLVSGQIDVSALDLDAVVGEQVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHCCCCC
>Mature Secondary Structure 
TVWRESVLGDLCTRVTVGHVGKMATEYVPDGVPFLRSQNVRPFVIDKRGLLYIGDDFNA
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCEEEEECCCEEEECCCCCH
KLRKSALTAGDVVIVRTGYPGTAAVVPEDLDGSNCADLVVITPSDALNPHVLAALFNSVY
HHHHHHCCCCCEEEEEECCCCCEEECCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHH
GQHAVSSQLVGSAQQHFNVGSAKTMRVRLPDRAEQDHIAAVLCSINDLIENNRRRVEVLE
HHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHH
GMARTIYREWFVKFRYPGNEGVPLVDSALGPAPKGWEVANLFDAADVGFGYSFKSPRFSN
HHHHHHHHHHEEEEECCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCC
SGPFQVIRIRDIPVGISRTYTDEAADPRYAVYDDDVLIGMDGDFHMTVWTGEDAWLNQRV
CCCEEEEEEEECCCCCCCCCCCCCCCCCEEEECCCEEEECCCCEEEEEECCCCHHHHHHH
TRLRPRLGLSALHLLLAIEEQIKDWNRAIVGTTVAHLGKKHLQLVNVLVPNDAVRIDASV
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEEHHH
VFAPIMEERRALIQSSRRLAALRDLLLPKLVSGQIDVSALDLDAVVGEQVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6304321 [H]