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The map label for this gene is hetN [H]

Identifier: 108763970

GI number: 108763970

Start: 2973802

End: 2974764

Strand: Direct

Name: hetN [H]

Synonym: MXAN_2554

Alternate gene names: 108763970

Gene position: 2973802-2974764 (Clockwise)

Preceding gene: 108760907

Following gene: 108760968

Centisome position: 32.54

GC content: 69.99

Gene sequence:

>963_bases
GTGCCCGCCATGAAGCCACTCGAAGGACGCGTCGCTCTGGTCGCTGGAGCCACCCGAGGCGCGGGGCGTGGCATCGCCAC
CATGTTGGGAGAGGCGGGCGCCACCGTGTACTGCACCGGGCGCAGCGTGCGCGGACGGCCCGCGACGGGCTCGCGTCCGG
AGACCATCGAGGAGACCGCCGAAATCGTCGACGCCAAGGGTGGCCGGGGCATCGCCGTCCGCGTGGACCATTCCGTCGAA
TCGGAGGTCGAAGCCCTTTGCGCGCGCATCCAGCGGGAGCAGGGGCGGCTCGACATCCTGGTGAACGACATCTGGGGCGG
CGACGGACTCACCGAGTTCGGCCCGGCGTTCTGGAAACAGTCCGCCGCGAAGGGGCAGCAGATGTTCGAGCGCGCCGTCT
TCACGCACCTGCTCACCAGCCGCCACGCCGTGCCGCTCATGCTGGGCGGTGAGCGGGGGCTCATCGTCGAAATCACGGAT
GGGGACTCGTTCGGCTACCGCGGCAACCTCTGGTACGACCTGGTCAAGATGTCCGTCATCCGGCTCGCCTTCGGGATGTC
CTGGGAGTTGCGCCGCACGAAGGTCACCGCGCTGGCGCTGACGCCCGGCTTCCTCCGCTCCGAGGAGATGCTGGAGAACT
TCGGCGTCACGGAAGCGAACTGGCGCGAGGGCGCGGCGAAGGATCCGCACTTCATCGCCTCGGAGAGTCCCTGCTACGTG
GGCCGGGCGGTGGCGGCGCTCGCGGCGGATCCGAACGTGGGCGCCAAGGCCGGCCGCGTCTTCAGCTCCTGGGCCCTGGC
CCGCGAATACGGCTTCACGGACGCCGACGGCTCCCAGCCGCATTGGGGCGACTACTTCGCGCGCGCTTTCGGCAGGCCGT
ACCAGGTCGCGGACGAGGACGCCTACACGTCCTGGCGCGACGGCCCCATGGAGATTGCCAGCCCGGATTGGCCCCTGGGC
TGA

Upstream 100 bases:

>100_bases
AAGTCTAGGCGGGGAATCATGACAGGGGATGTCAGGATTCCCCGCCTAGGGTGCGAACACGAACCCACTGCGGTCCACGG
TCGCCCGTGGGCTTGGAGGA

Downstream 100 bases:

>100_bases
GAGGCCACCGAATGAGTGGTTGCCTACCTGTGTCTACATGGTGCCTGCACTCTGACGGGGAGCGGCCACCCACCGCCACC
GGGCGACCATTCAGGGGCCG

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MPAMKPLEGRVALVAGATRGAGRGIATMLGEAGATVYCTGRSVRGRPATGSRPETIEETAEIVDAKGGRGIAVRVDHSVE
SEVEALCARIQREQGRLDILVNDIWGGDGLTEFGPAFWKQSAAKGQQMFERAVFTHLLTSRHAVPLMLGGERGLIVEITD
GDSFGYRGNLWYDLVKMSVIRLAFGMSWELRRTKVTALALTPGFLRSEEMLENFGVTEANWREGAAKDPHFIASESPCYV
GRAVAALAADPNVGAKAGRVFSSWALAREYGFTDADGSQPHWGDYFARAFGRPYQVADEDAYTSWRDGPMEIASPDWPLG

Sequences:

>Translated_320_residues
MPAMKPLEGRVALVAGATRGAGRGIATMLGEAGATVYCTGRSVRGRPATGSRPETIEETAEIVDAKGGRGIAVRVDHSVE
SEVEALCARIQREQGRLDILVNDIWGGDGLTEFGPAFWKQSAAKGQQMFERAVFTHLLTSRHAVPLMLGGERGLIVEITD
GDSFGYRGNLWYDLVKMSVIRLAFGMSWELRRTKVTALALTPGFLRSEEMLENFGVTEANWREGAAKDPHFIASESPCYV
GRAVAALAADPNVGAKAGRVFSSWALAREYGFTDADGSQPHWGDYFARAFGRPYQVADEDAYTSWRDGPMEIASPDWPLG
>Mature_319_residues
PAMKPLEGRVALVAGATRGAGRGIATMLGEAGATVYCTGRSVRGRPATGSRPETIEETAEIVDAKGGRGIAVRVDHSVES
EVEALCARIQREQGRLDILVNDIWGGDGLTEFGPAFWKQSAAKGQQMFERAVFTHLLTSRHAVPLMLGGERGLIVEITDG
DSFGYRGNLWYDLVKMSVIRLAFGMSWELRRTKVTALALTPGFLRSEEMLENFGVTEANWREGAAKDPHFIASESPCYVG
RAVAALAADPNVGAKAGRVFSSWALAREYGFTDADGSQPHWGDYFARAFGRPYQVADEDAYTSWRDGPMEIASPDWPLG

Specific function: May be involved in repressing heterocyst differentiation and may be essential for preventing all vegetative cells from differentiating [H]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI209862901, Length=282, Percent_Identity=35.8156028368794, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI19923983, Length=282, Percent_Identity=35.8156028368794, Blast_Score=152, Evalue=5e-37,
Organism=Escherichia coli, GI87082100, Length=260, Percent_Identity=26.1538461538462, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17555612, Length=277, Percent_Identity=35.3790613718412, Blast_Score=153, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI71997099, Length=285, Percent_Identity=34.3859649122807, Blast_Score=145, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI86565303, Length=286, Percent_Identity=31.4685314685315, Blast_Score=120, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 34734; Mature: 34602

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAMKPLEGRVALVAGATRGAGRGIATMLGEAGATVYCTGRSVRGRPATGSRPETIEETA
CCCCCCCCCCEEEEEECCCCCCCHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHH
EIVDAKGGRGIAVRVDHSVESEVEALCARIQREQGRLDILVNDIWGGDGLTEFGPAFWKQ
HHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHH
SAAKGQQMFERAVFTHLLTSRHAVPLMLGGERGLIVEITDGDSFGYRGNLWYDLVKMSVI
HHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEECCCCCCCCCCHHHHHHHHHHH
RLAFGMSWELRRTKVTALALTPGFLRSEEMLENFGVTEANWREGAAKDPHFIASESPCYV
HHHHCCCEEEEHEEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCHH
GRAVAALAADPNVGAKAGRVFSSWALAREYGFTDADGSQPHWGDYFARAFGRPYQVADED
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCEECCCC
AYTSWRDGPMEIASPDWPLG
CCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PAMKPLEGRVALVAGATRGAGRGIATMLGEAGATVYCTGRSVRGRPATGSRPETIEETA
CCCCCCCCCEEEEEECCCCCCCHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHH
EIVDAKGGRGIAVRVDHSVESEVEALCARIQREQGRLDILVNDIWGGDGLTEFGPAFWKQ
HHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHH
SAAKGQQMFERAVFTHLLTSRHAVPLMLGGERGLIVEITDGDSFGYRGNLWYDLVKMSVI
HHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEECCCCCCCCCCHHHHHHHHHHH
RLAFGMSWELRRTKVTALALTPGFLRSEEMLENFGVTEANWREGAAKDPHFIASESPCYV
HHHHCCCEEEEHEEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCHH
GRAVAALAADPNVGAKAGRVFSSWALAREYGFTDADGSQPHWGDYFARAFGRPYQVADED
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCEECCCC
AYTSWRDGPMEIASPDWPLG
CCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8157596; 11759840 [H]