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The map label for this gene is afsK [H]

Identifier: 108763949

GI number: 108763949

Start: 1758108

End: 1759181

Strand: Direct

Name: afsK [H]

Synonym: MXAN_1497

Alternate gene names: 108763949

Gene position: 1758108-1759181 (Clockwise)

Preceding gene: 108763147

Following gene: 108758366

Centisome position: 19.24

GC content: 66.29

Gene sequence:

>1074_bases
ATGTCGGATTCATCTCGCTCCGTATTCTTTGGCGCCAATGCTGCGCGGACCGGACACTTCGAGGGAACGGGGCCGCTCGT
GGTCAAGCGAGCCCGCTGGAAGTTCAAGCCGGGCACGCTTGCGACCACACGCAACACGCCTGCAATCCACGATGGCGTGC
TGTTCGCGAACTTCGACAATGACAAGCTCTACGCGCTTGACCTCGCGAAGGGAAAAGAGCTCTGGAGCGTGCGGGTCGGG
GGGCGCGTTTCTGAGAGCATCTCGAATCCGATGGTTGCGCATGGTTTGCTCTTCGTCGTCGGTGGCGGGCAGTGTCACGC
CGTCGATCTTGGCACGCACGCCATCCGCTGGAGCGTCTCGTGTGACTCCGAGGCGACCTCCTCGCCAATCGTTGTCGACG
ACGACGTCTACGTGGGAGCGCGGCTCGGTGGGGTGGTCGCCATCGACGCGCGTACGGGAGTAGAGCGATGGCGCGTGCAG
CTACGCTGTGGTGAGAGTGTGGGGTCCGCGGTCAGCGTGACGCGCGATCAGGTCGTCGTCGGGACCAGACGCGACTTCGT
CGAGGGCCACGTCGTCGCGCTCGACCGCGCCACGGGGGGCGAGCGATGGTCGGCGAAGGCCGGTGCGATGGCCAACGGCG
GAGCGCCCGCGATCGAAGGCAGCACGGTTTATGCCCTGTCCGGTCTGGGGCAGTGCCTTCGCGCGCTCGACCTCGCCAGT
GGCAAAGAGCGTTGGTTGTATGAGACGGGCGGCGCGCTGTGGGGAACGCCCGCCGTTGCGGACGGCGTCGTGTGCTTCAC
CGGCTATCACGGGATTCTCCACGCGCTGGACCAAGATACCGGGAAAGAGATTTGGTCGGTCGCGCTCGACAATCCCCCGA
AGGATACGGTCTCACCGACGATCGCAGGTGGCGTCGTCTACATGGGGGCCGGCAACGTCGTCCACGCCTGGACGCTCCGG
GAGGGAACAGAGCGCTGGCGGTGGAAGGCTCCCTACCGCGTGTCGACGGCACCGCTCGTCGCCGACGGCACGGTCTACGT
GGGCTGTGACCGCGCGATCGTCGCGCTGGGGTAG

Upstream 100 bases:

>100_bases
TGCAGCCAACTTGAAGGCGACTGGTCCGAGGTGCCTCCGCTTCCAGACGAGGGTCGTCGCGACGAACGCCATCTGCCGGG
CTACTAAAAGGGATCTACCC

Downstream 100 bases:

>100_bases
CGTCGGCCACCCGGCTTCCACATGGCTCGTAGGCCCAGGCCCCTGCCGCGCCTCAACATGGCCTCTATCCCGTCTATACG
CACGAGACACGCCTGAACAG

Product: PQQ repeat-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MSDSSRSVFFGANAARTGHFEGTGPLVVKRARWKFKPGTLATTRNTPAIHDGVLFANFDNDKLYALDLAKGKELWSVRVG
GRVSESISNPMVAHGLLFVVGGGQCHAVDLGTHAIRWSVSCDSEATSSPIVVDDDVYVGARLGGVVAIDARTGVERWRVQ
LRCGESVGSAVSVTRDQVVVGTRRDFVEGHVVALDRATGGERWSAKAGAMANGGAPAIEGSTVYALSGLGQCLRALDLAS
GKERWLYETGGALWGTPAVADGVVCFTGYHGILHALDQDTGKEIWSVALDNPPKDTVSPTIAGGVVYMGAGNVVHAWTLR
EGTERWRWKAPYRVSTAPLVADGTVYVGCDRAIVALG

Sequences:

>Translated_357_residues
MSDSSRSVFFGANAARTGHFEGTGPLVVKRARWKFKPGTLATTRNTPAIHDGVLFANFDNDKLYALDLAKGKELWSVRVG
GRVSESISNPMVAHGLLFVVGGGQCHAVDLGTHAIRWSVSCDSEATSSPIVVDDDVYVGARLGGVVAIDARTGVERWRVQ
LRCGESVGSAVSVTRDQVVVGTRRDFVEGHVVALDRATGGERWSAKAGAMANGGAPAIEGSTVYALSGLGQCLRALDLAS
GKERWLYETGGALWGTPAVADGVVCFTGYHGILHALDQDTGKEIWSVALDNPPKDTVSPTIAGGVVYMGAGNVVHAWTLR
EGTERWRWKAPYRVSTAPLVADGTVYVGCDRAIVALG
>Mature_356_residues
SDSSRSVFFGANAARTGHFEGTGPLVVKRARWKFKPGTLATTRNTPAIHDGVLFANFDNDKLYALDLAKGKELWSVRVGG
RVSESISNPMVAHGLLFVVGGGQCHAVDLGTHAIRWSVSCDSEATSSPIVVDDDVYVGARLGGVVAIDARTGVERWRVQL
RCGESVGSAVSVTRDQVVVGTRRDFVEGHVVALDRATGGERWSAKAGAMANGGAPAIEGSTVYALSGLGQCLRALDLASG
KERWLYETGGALWGTPAVADGVVCFTGYHGILHALDQDTGKEIWSVALDNPPKDTVSPTIAGGVVYMGAGNVVHAWTLRE
GTERWRWKAPYRVSTAPLVADGTVYVGCDRAIVALG

Specific function: Involved in the regulation of secondary metabolism by phosphorylating, on both Ser and Thr, the AfsR global regulatory protein involved in the control of secondary metabolism [H]

COG id: COG1520

COG function: function code S; FOG: WD40-like repeat

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR018391
- InterPro:   IPR002372
- InterPro:   IPR000719
- InterPro:   IPR017441
- InterPro:   IPR011047
- InterPro:   IPR017442
- InterPro:   IPR008271 [H]

Pfam domain/function: PF00069 Pkinase; PF01011 PQQ [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 37750; Mature: 37619

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: PS00626 RCC1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSSRSVFFGANAARTGHFEGTGPLVVKRARWKFKPGTLATTRNTPAIHDGVLFANFDN
CCCCCCEEEEECCCCCCCCCCCCCCEEEEECCEEECCCCEEECCCCCCEECCEEEEECCC
DKLYALDLAKGKELWSVRVGGRVSESISNPMVAHGLLFVVGGGQCHAVDLGTHAIRWSVS
CEEEEEEECCCCEEEEEEECCEEHHHHCCCCEECEEEEEEECCEEEEEECCCEEEEEEEE
CDSEATSSPIVVDDDVYVGARLGGVVAIDARTGVERWRVQLRCGESVGSAVSVTRDQVVV
CCCCCCCCCEEEECCEEEEEECCCEEEEECCCCCCCEEEEEEECCCCCCEEEEECCEEEE
GTRRDFVEGHVVALDRATGGERWSAKAGAMANGGAPAIEGSTVYALSGLGQCLRALDLAS
ECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHCCC
GKERWLYETGGALWGTPAVADGVVCFTGYHGILHALDQDTGKEIWSVALDNPPKDTVSPT
CCCCEEEECCCCEECCCCHHCCEEEEECHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCE
IAGGVVYMGAGNVVHAWTLREGTERWRWKAPYRVSTAPLVADGTVYVGCDRAIVALG
ECCCEEEEECCCEEEEEEECCCCHHCEECCCEEECCCCEEECCEEEEECCEEEEEEC
>Mature Secondary Structure 
SDSSRSVFFGANAARTGHFEGTGPLVVKRARWKFKPGTLATTRNTPAIHDGVLFANFDN
CCCCCEEEEECCCCCCCCCCCCCCEEEEECCEEECCCCEEECCCCCCEECCEEEEECCC
DKLYALDLAKGKELWSVRVGGRVSESISNPMVAHGLLFVVGGGQCHAVDLGTHAIRWSVS
CEEEEEEECCCCEEEEEEECCEEHHHHCCCCEECEEEEEEECCEEEEEECCCEEEEEEEE
CDSEATSSPIVVDDDVYVGARLGGVVAIDARTGVERWRVQLRCGESVGSAVSVTRDQVVV
CCCCCCCCCEEEECCEEEEEECCCEEEEECCCCCCCEEEEEEECCCCCCEEEEECCEEEE
GTRRDFVEGHVVALDRATGGERWSAKAGAMANGGAPAIEGSTVYALSGLGQCLRALDLAS
ECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHCCC
GKERWLYETGGALWGTPAVADGVVCFTGYHGILHALDQDTGKEIWSVALDNPPKDTVSPT
CCCCEEEECCCCEECCCCHHCCEEEEECHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCE
IAGGVVYMGAGNVVHAWTLREGTERWRWKAPYRVSTAPLVADGTVYVGCDRAIVALG
ECCCEEEEECCCEEEEEEECCCCHHCEECCCEEECCCCEEECCEEEEECCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8063104; 8635757; 12000953 [H]