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The map label for this gene is nla19 [H]

Identifier: 108763819

GI number: 108763819

Start: 1256504

End: 1257952

Strand: Direct

Name: nla19 [H]

Synonym: MXAN_1078

Alternate gene names: 108763819

Gene position: 1256504-1257952 (Clockwise)

Preceding gene: 108763472

Following gene: 108761269

Centisome position: 13.75

GC content: 71.36

Gene sequence:

>1449_bases
ATGACCGACGCGAACACTCCGCCGACCCGAGGACGGCTCCTCGTCGTGGACGACCAGCGCAACATGCGCGCCACCACCGC
CCTGTTGTTGCGGGCGGAGAACTACACCGTCTTCGAGGCCGCCACCGGCGAGGAAGCCCTGGCCCAGCTCGCCAGCGGCA
GCATCGACCTGCTGCTGACGGACCTGAAAATGGAGCCCATGGACGGGCTCACGCTCCTGCGGCGCGCGCTGGAGGTGGCT
CCCCGGCTCCAGGTCATCATGATGACGGCCTTCGGCTCCATCGAGAGCGCCGTGGAGGCCATGCGCCTGGGGGCCTACGA
CTATGTCACCAAGCCCTTCAAGGAGAGCGAGCTGCGCTACCGCGTGGAGCGCGCCCTGGAGCGCGCGCGCCTGCAGCGCG
ACGTGGACAACCTCACCACCGACTTCAACCAGCGCCACGGCCTGTCCGCCCTGGTGGGGCGCAGCGCCGCCATGCGCGAG
CTCACCACGCGGCTGATGCGCGTGGCGCAGAGTGACGCCACCGTCCTCATCCAGGGCGAGAGCGGCACGGGCAAGGAGCT
GGTGGCGCGCGCGCTCCATGCGCACAGCCGCCGCAAGGCCCGCTCCTTCGTGCCTGTCAACTGCGCGGCCATCAGCGAGT
CCCTGCTGGAGAGCGAGCTGTTCGGCCACGCCAAGGGCGCCTTCACCGGTGCGGTGAAGTCCCGCCGGGGCCTCTTCGAG
GAGGCGGACGGCGGCACGCTCTTCATCGACGAGGTGACGGAGACCAGCCCCACCTTCCAGTCCAAGCTGCTGCGCGCCCT
CCAGGAGGGCGAGGTCCGCCGCGTCGGTGAGTCCACCGCGCTGCGTGTGGATGTGCGCATCGTCGCCGCCACCAACCGGG
ACATCGAGCTGGAGGTGCGCGACAAGCGCTTCCGGCAGGACCTCTACTACCGCCTCAACGTGGTGGCCCTCCGCGTCCCG
CCCCTGCGCGAGCGCCTGGAGGACGTGCCAGCGCTGGCGGAGCACTTCCTGGAGCGGGCCAATGCCCGCAGCCCCAACCC
CAAGCGCCTTTCCGCCGCCGCGGTGTCTCACCTGATGAGCTACGGCTTCCCCGGCAACGTGCGCGAGCTGGAGAACCTGG
TGGAGCAGGCCGCCGCGCTCGCGGAGGGCGATGAGCTGCTGCCCGAGGACTTCCCCGTGCGGCAGGGCCGCATGACGCCG
GCCCATGGCACCCCCAGCGTCGCCTTCCTGGACGGGCAGGGCGGGGCGCTCGGGCGCAACGCCAGCGCGGGGCCCACGCT
GGCCCAGGTGGTGGAAGAGGCGGAGCGCCACGCCATCACCCAGGCCCTGGAGCGGCACGGGGTGGACCTGGCGCGCGTCG
CGGATGAGCTCGGCGTCTCCTCCACCACGCTCTGGCGGAAGATGAAGCGGCTCAACCTCCGCCCCCCCAGTGAGCTGGCC
CGGGAATAG

Upstream 100 bases:

>100_bases
TCCTCGAGGAGCACCGGGGCGAAATCGCCGTGGACAGTATTCCGGGGCGCGGTACCACCTTCACCTTCCGGCTGCCGTTC
TCGCAGCCTCCGTCCTTCCC

Downstream 100 bases:

>100_bases
CCCTGAAGTAGGGGGAAGGCTCACCCATGTAACTTTCCCGCGGCCATGGATTCAGATCCGAAATGGACGGGTTCATAGGT
GAAAAAGACAAATAGTTGAA

Product: sigma-54 dependent DNA-binding response regulator Nla19

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 482; Mature: 481

Protein sequence:

>482_residues
MTDANTPPTRGRLLVVDDQRNMRATTALLLRAENYTVFEAATGEEALAQLASGSIDLLLTDLKMEPMDGLTLLRRALEVA
PRLQVIMMTAFGSIESAVEAMRLGAYDYVTKPFKESELRYRVERALERARLQRDVDNLTTDFNQRHGLSALVGRSAAMRE
LTTRLMRVAQSDATVLIQGESGTGKELVARALHAHSRRKARSFVPVNCAAISESLLESELFGHAKGAFTGAVKSRRGLFE
EADGGTLFIDEVTETSPTFQSKLLRALQEGEVRRVGESTALRVDVRIVAATNRDIELEVRDKRFRQDLYYRLNVVALRVP
PLRERLEDVPALAEHFLERANARSPNPKRLSAAAVSHLMSYGFPGNVRELENLVEQAAALAEGDELLPEDFPVRQGRMTP
AHGTPSVAFLDGQGGALGRNASAGPTLAQVVEEAERHAITQALERHGVDLARVADELGVSSTTLWRKMKRLNLRPPSELA
RE

Sequences:

>Translated_482_residues
MTDANTPPTRGRLLVVDDQRNMRATTALLLRAENYTVFEAATGEEALAQLASGSIDLLLTDLKMEPMDGLTLLRRALEVA
PRLQVIMMTAFGSIESAVEAMRLGAYDYVTKPFKESELRYRVERALERARLQRDVDNLTTDFNQRHGLSALVGRSAAMRE
LTTRLMRVAQSDATVLIQGESGTGKELVARALHAHSRRKARSFVPVNCAAISESLLESELFGHAKGAFTGAVKSRRGLFE
EADGGTLFIDEVTETSPTFQSKLLRALQEGEVRRVGESTALRVDVRIVAATNRDIELEVRDKRFRQDLYYRLNVVALRVP
PLRERLEDVPALAEHFLERANARSPNPKRLSAAAVSHLMSYGFPGNVRELENLVEQAAALAEGDELLPEDFPVRQGRMTP
AHGTPSVAFLDGQGGALGRNASAGPTLAQVVEEAERHAITQALERHGVDLARVADELGVSSTTLWRKMKRLNLRPPSELA
RE
>Mature_481_residues
TDANTPPTRGRLLVVDDQRNMRATTALLLRAENYTVFEAATGEEALAQLASGSIDLLLTDLKMEPMDGLTLLRRALEVAP
RLQVIMMTAFGSIESAVEAMRLGAYDYVTKPFKESELRYRVERALERARLQRDVDNLTTDFNQRHGLSALVGRSAAMREL
TTRLMRVAQSDATVLIQGESGTGKELVARALHAHSRRKARSFVPVNCAAISESLLESELFGHAKGAFTGAVKSRRGLFEE
ADGGTLFIDEVTETSPTFQSKLLRALQEGEVRRVGESTALRVDVRIVAATNRDIELEVRDKRFRQDLYYRLNVVALRVPP
LRERLEDVPALAEHFLERANARSPNPKRLSAAAVSHLMSYGFPGNVRELENLVEQAAALAEGDELLPEDFPVRQGRMTPA
HGTPSVAFLDGQGGALGRNASAGPTLAQVVEEAERHAITQALERHGVDLARVADELGVSSTTLWRKMKRLNLRPPSELAR
E

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=459, Percent_Identity=44.6623093681917, Blast_Score=353, Evalue=1e-98,
Organism=Escherichia coli, GI1788550, Length=469, Percent_Identity=39.8720682302772, Blast_Score=337, Evalue=1e-93,
Organism=Escherichia coli, GI1790299, Length=479, Percent_Identity=41.1273486430063, Blast_Score=310, Evalue=2e-85,
Organism=Escherichia coli, GI1788905, Length=371, Percent_Identity=44.743935309973, Blast_Score=301, Evalue=9e-83,
Organism=Escherichia coli, GI87082117, Length=355, Percent_Identity=43.943661971831, Blast_Score=266, Evalue=2e-72,
Organism=Escherichia coli, GI87082152, Length=335, Percent_Identity=45.9701492537313, Blast_Score=245, Evalue=5e-66,
Organism=Escherichia coli, GI1789087, Length=354, Percent_Identity=42.090395480226, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI1789233, Length=338, Percent_Identity=40.2366863905325, Blast_Score=230, Evalue=2e-61,
Organism=Escherichia coli, GI1786524, Length=339, Percent_Identity=39.5280235988201, Blast_Score=218, Evalue=8e-58,
Organism=Escherichia coli, GI1787583, Length=328, Percent_Identity=37.8048780487805, Blast_Score=205, Evalue=5e-54,
Organism=Escherichia coli, GI87081872, Length=230, Percent_Identity=45.2173913043478, Blast_Score=188, Evalue=6e-49,
Organism=Escherichia coli, GI87081858, Length=304, Percent_Identity=30.2631578947368, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1789828, Length=243, Percent_Identity=33.3333333333333, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1788191, Length=120, Percent_Identity=35.8333333333333, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1789809, Length=188, Percent_Identity=29.7872340425532, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1790863, Length=117, Percent_Identity=32.4786324786325, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 53192; Mature: 53061

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDANTPPTRGRLLVVDDQRNMRATTALLLRAENYTVFEAATGEEALAQLASGSIDLLLT
CCCCCCCCCCCEEEEEECCCCHHHHHHHEEEECCCEEEECCCCHHHHHHHHCCCEEEEEE
DLKMEPMDGLTLLRRALEVAPRLQVIMMTAFGSIESAVEAMRLGAYDYVTKPFKESELRY
CCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHCCHHHHCCCCHHHHHHH
RVERALERARLQRDVDNLTTDFNQRHGLSALVGRSAAMRELTTRLMRVAQSDATVLIQGE
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
SGTGKELVARALHAHSRRKARSFVPVNCAAISESLLESELFGHAKGAFTGAVKSRRGLFE
CCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCC
EADGGTLFIDEVTETSPTFQSKLLRALQEGEVRRVGESTALRVDVRIVAATNRDIELEVR
CCCCCEEEEECCCCCCCHHHHHHHHHHHHCHHHHCCCCCEEEEEEEEEEECCCCEEEEEH
DKRFRQDLYYRLNVVALRVPPLRERLEDVPALAEHFLERANARSPNPKRLSAAAVSHLMS
HHHHHHHHHHEEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
YGFPGNVRELENLVEQAAALAEGDELLPEDFPVRQGRMTPAHGTPSVAFLDGQGGALGRN
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCC
ASAGPTLAQVVEEAERHAITQALERHGVDLARVADELGVSSTTLWRKMKRLNLRPPSELA
CCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHH
RE
CC
>Mature Secondary Structure 
TDANTPPTRGRLLVVDDQRNMRATTALLLRAENYTVFEAATGEEALAQLASGSIDLLLT
CCCCCCCCCCEEEEEECCCCHHHHHHHEEEECCCEEEECCCCHHHHHHHHCCCEEEEEE
DLKMEPMDGLTLLRRALEVAPRLQVIMMTAFGSIESAVEAMRLGAYDYVTKPFKESELRY
CCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHCCHHHHCCCCHHHHHHH
RVERALERARLQRDVDNLTTDFNQRHGLSALVGRSAAMRELTTRLMRVAQSDATVLIQGE
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
SGTGKELVARALHAHSRRKARSFVPVNCAAISESLLESELFGHAKGAFTGAVKSRRGLFE
CCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCC
EADGGTLFIDEVTETSPTFQSKLLRALQEGEVRRVGESTALRVDVRIVAATNRDIELEVR
CCCCCEEEEECCCCCCCHHHHHHHHHHHHCHHHHCCCCCEEEEEEEEEEECCCCEEEEEH
DKRFRQDLYYRLNVVALRVPPLRERLEDVPALAEHFLERANARSPNPKRLSAAAVSHLMS
HHHHHHHHHHEEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
YGFPGNVRELENLVEQAAALAEGDELLPEDFPVRQGRMTPAHGTPSVAFLDGQGGALGRN
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCC
ASAGPTLAQVVEEAERHAITQALERHGVDLARVADELGVSSTTLWRKMKRLNLRPPSELA
CCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHH
RE
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]