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The map label for this gene is ttgG [H]

Identifier: 108763599

GI number: 108763599

Start: 102329

End: 103465

Strand: Direct

Name: ttgG [H]

Synonym: MXAN_0091

Alternate gene names: 108763599

Gene position: 102329-103465 (Clockwise)

Preceding gene: 108758237

Following gene: 108762552

Centisome position: 1.12

GC content: 69.74

Gene sequence:

>1137_bases
ATGCCTATCCAACGGTCGAAGCGCCTTCTTCTTGCATCGACGCTGCTCCCGCTTCTGGCCTGTGACGGCAAGCAGGAAGA
AGCAGCCTTCGCACCGCCGGTCCAGAAGGTGTCCACGCTGAAGGTGCAAGGGGAGGCCGTTGTCCTTCACGACGAATTCC
CCGCGCGTGTCTCCGCGTTCCGGGTCGCGGAAGTCCGCCCTCAGGTGGGCGGGCTCGTGCGCAGCCGGCGCTTCTCCGAA
GGAGACACGGTCCAGAAGGGGCAGCCGCTCTACCAACTGGAAGCGGCGGTGTTCCGCGCGAATGTAGAAGGCGCGGCGGC
GGCCCATGCGGCCAGTGAGGCCGGGCGGCTCCAAGCGGAGCTGCATGCGGGGCGCATCCAGTCCCTCTTCGAGAAAGGCG
CGAGCACCCAGCAGGCGCACGATGACGCCCGGGCCGCGCTCGCCATCGCGAATGCGGAGGTGGCGCGCGCCCGCGCGGCG
CTGGACAGGGCCCGCGTCGACCTGGACTACGCCACGATTACCGCCCCCATCGCGGGGCACATCGGCATCTCCCAGGTCAA
TGAAGGCGCGCTCGTCGGCCCCGCGGATGCCACGCCGTTGAGCGTCATCCAGCAGATTGACCGCGTCTTCGTCGACATCA
AGTCACCCGTGGAGCGCGCGGCGGGCTTGCAGTCACTCCAGGGAGGCACCGGAGAGGCGGGGGCGGAAGTCATCGTGCTC
TCCTCGACGGGGGCGCCCTATCCGGAGCGAGGCCGCGTTCAGTTCTCGGACATCTCGGTCGACCCCGGGTCCGGCGAGCT
CACGGTGCGCGCCCTGGTCCCCAACGCACAGCGGAAGCTCCTGCCGGGCATGTTCGTGAAGGCGCGCGTCGTGCTCGGAG
AGGTGGCCGGTGCGCTCCTCGTTCCCCAGCAGGCCGTGCTTCACGACGCGCAGGGCCAGGCGCAGGTCTTCATCGTCCGA
GAGGACAACACCGCGGAGGCGCGCAACGTCCGCGCCGGACGCATCGTCAGCGGACGCTACCTGGTGGAGGAGGGACTCTC
CGCCGGAGAGCGTGTCGTGGTCGAGGGGCAGGACCGTCTTGCGCCAGGCCAGCAGGTCACCCCCGTCGAGTGGCAGCACG
CCCCGGCCTCGCGCTGA

Upstream 100 bases:

>100_bases
AGGTGACGTTTCATCCCCTGGCTGCTGGCGGACCAGGGCGTGGTGCTGTGTGAAAAGTACGCTTTTACGTTTTCTCCGAC
GTTTTCCTCGCCAGACGACA

Downstream 100 bases:

>100_bases
ACCTGGAGTGAGCCGTGCCAAGATTCTTCATTGAACGCCCGGTCTTCGCCTGGGTGATTGCCATCTTCATCGTGCTCGCC
GGAGCCATCTCCATTCCCCG

Product: HAE1 family efflux transporter MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MPIQRSKRLLLASTLLPLLACDGKQEEAAFAPPVQKVSTLKVQGEAVVLHDEFPARVSAFRVAEVRPQVGGLVRSRRFSE
GDTVQKGQPLYQLEAAVFRANVEGAAAAHAASEAGRLQAELHAGRIQSLFEKGASTQQAHDDARAALAIANAEVARARAA
LDRARVDLDYATITAPIAGHIGISQVNEGALVGPADATPLSVIQQIDRVFVDIKSPVERAAGLQSLQGGTGEAGAEVIVL
SSTGAPYPERGRVQFSDISVDPGSGELTVRALVPNAQRKLLPGMFVKARVVLGEVAGALLVPQQAVLHDAQGQAQVFIVR
EDNTAEARNVRAGRIVSGRYLVEEGLSAGERVVVEGQDRLAPGQQVTPVEWQHAPASR

Sequences:

>Translated_378_residues
MPIQRSKRLLLASTLLPLLACDGKQEEAAFAPPVQKVSTLKVQGEAVVLHDEFPARVSAFRVAEVRPQVGGLVRSRRFSE
GDTVQKGQPLYQLEAAVFRANVEGAAAAHAASEAGRLQAELHAGRIQSLFEKGASTQQAHDDARAALAIANAEVARARAA
LDRARVDLDYATITAPIAGHIGISQVNEGALVGPADATPLSVIQQIDRVFVDIKSPVERAAGLQSLQGGTGEAGAEVIVL
SSTGAPYPERGRVQFSDISVDPGSGELTVRALVPNAQRKLLPGMFVKARVVLGEVAGALLVPQQAVLHDAQGQAQVFIVR
EDNTAEARNVRAGRIVSGRYLVEEGLSAGERVVVEGQDRLAPGQQVTPVEWQHAPASR
>Mature_377_residues
PIQRSKRLLLASTLLPLLACDGKQEEAAFAPPVQKVSTLKVQGEAVVLHDEFPARVSAFRVAEVRPQVGGLVRSRRFSEG
DTVQKGQPLYQLEAAVFRANVEGAAAAHAASEAGRLQAELHAGRIQSLFEKGASTQQAHDDARAALAIANAEVARARAAL
DRARVDLDYATITAPIAGHIGISQVNEGALVGPADATPLSVIQQIDRVFVDIKSPVERAAGLQSLQGGTGEAGAEVIVLS
STGAPYPERGRVQFSDISVDPGSGELTVRALVPNAQRKLLPGMFVKARVVLGEVAGALLVPQQAVLHDAQGQAQVFIVRE
DNTAEARNVRAGRIVSGRYLVEEGLSAGERVVVEGQDRLAPGQQVTPVEWQHAPASR

Specific function: The periplasmic linker component of an organic solvent efflux pump. Involved in export of a number of organic solvents, including toluene and styrene. This is the most important solvent efflux pump in this strain, although it can export AMP and some antib

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789665, Length=371, Percent_Identity=39.622641509434, Blast_Score=231, Evalue=6e-62,
Organism=Escherichia coli, GI1786668, Length=362, Percent_Identity=39.5027624309392, Blast_Score=228, Evalue=4e-61,
Organism=Escherichia coli, GI1789929, Length=366, Percent_Identity=37.7049180327869, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI87082036, Length=323, Percent_Identity=27.5541795665635, Blast_Score=108, Evalue=8e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 39947; Mature: 39816

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIQRSKRLLLASTLLPLLACDGKQEEAAFAPPVQKVSTLKVQGEAVVLHDEFPARVSAF
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHEEEEEECCEEEEECCCCCHHHHH
RVAEVRPQVGGLVRSRRFSEGDTVQKGQPLYQLEAAVFRANVEGAAAAHAASEAGRLQAE
HHHHHCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
LHAGRIQSLFEKGASTQQAHDDARAALAIANAEVARARAALDRARVDLDYATITAPIAGH
HHHHHHHHHHHCCCCCHHHHHHHHHEEEEHHHHHHHHHHHHHHHHEECCHHEEEECHHCC
IGISQVNEGALVGPADATPLSVIQQIDRVFVDIKSPVERAAGLQSLQGGTGEAGAEVIVL
CCHHCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
SSTGAPYPERGRVQFSDISVDPGSGELTVRALVPNAQRKLLPGMFVKARVVLGEVAGALL
ECCCCCCCCCCCEEEEEEEECCCCCCEEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHH
VPQQAVLHDAQGQAQVFIVREDNTAEARNVRAGRIVSGRYLVEEGLSAGERVVVEGQDRL
CCCHHHHHCCCCCEEEEEEECCCCCHHHCCCCCEEECCHHHHHHCCCCCCEEEEECCCCC
APGQQVTPVEWQHAPASR
CCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PIQRSKRLLLASTLLPLLACDGKQEEAAFAPPVQKVSTLKVQGEAVVLHDEFPARVSAF
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHEEEEEECCEEEEECCCCCHHHHH
RVAEVRPQVGGLVRSRRFSEGDTVQKGQPLYQLEAAVFRANVEGAAAAHAASEAGRLQAE
HHHHHCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
LHAGRIQSLFEKGASTQQAHDDARAALAIANAEVARARAALDRARVDLDYATITAPIAGH
HHHHHHHHHHHCCCCCHHHHHHHHHEEEEHHHHHHHHHHHHHHHHEECCHHEEEECHHCC
IGISQVNEGALVGPADATPLSVIQQIDRVFVDIKSPVERAAGLQSLQGGTGEAGAEVIVL
CCHHCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
SSTGAPYPERGRVQFSDISVDPGSGELTVRALVPNAQRKLLPGMFVKARVVLGEVAGALL
ECCCCCCCCCCCEEEEEEEECCCCCCEEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHH
VPQQAVLHDAQGQAQVFIVREDNTAEARNVRAGRIVSGRYLVEEGLSAGERVVVEGQDRL
CCCHHHHHCCCCCEEEEEEECCCCCHHHCCCCCEEECCHHHHHHCCCCCCEEEEECCCCC
APGQQVTPVEWQHAPASR
CCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11395460 [H]