Click here to switch to the map view.

The map label for this gene is pheA [H]

Identifier: 108763520

GI number: 108763520

Start: 3772001

End: 3772822

Strand: Reverse

Name: pheA [H]

Synonym: MXAN_3220

Alternate gene names: 108763520

Gene position: 3772822-3772001 (Counterclockwise)

Preceding gene: 108760492

Following gene: 108762158

Centisome position: 41.28

GC content: 73.48

Gene sequence:

>822_bases
ATGCCTGAGTCGCCGCGTCGCATCGCCTTCCAGGGCGAGCCTGGCGCCTACGGAGAAGAGGCCCTGCGCGCGCTGCATGG
CGCCGACGTGGAGGCCGTCCCCTGCCTCACCTTCCGCGCCGTCTTCGAAGCCGTGGCCGAAGGCCGCGTGCACGGCGGCG
TGGTGCCGGTGGAGAGCTCGCTGGGCGGGCCCGTGGCGGAGACGGTGGACCTGCTGCTGGAGCATGACGTGCCGGCGACG
GGCGAGCTGTCCCTGCGCATCCGCCACTGCCTGCTGGCCCCACCGGGCCTGTCACTGGACGACGTCCAGCAGGCCCTCTC
CCACCCGCAGGCCCTGGCGCAATGCGCGGGCTACCTGCGACGGCGGGGCATCTCACCGCTGCCGGAGGCGAACACCGCCA
TCGCCGCGCGAAAGGTGGCGGAGGAGAAGCCTCCGCACACGGCCGCCATCGCCAGCCGCATGTCCGCGGACCTGTACGGG
CTGGCCGTGCTGGAGGAAGGCGTGGAGGACTCGCCGGACAACTTCACGCGCTTCATCGCCCTGGGGACCGCGCCCGAACG
GACGTGGACGCGGCGGAAAACGGCGCTGGCCTTCACCGTGGAGAACGGGCCGGGCGCGCTGTTCCGCGTGATGAGCGCCT
TCTCCTCGCGCGGCCTCAACGTGGCGCGGCTGGAGTCCCGGCCGCAGCGCCGCGCCTGGGAGTACGTGTGGTGCCTGGAC
GTGGACGGCGCGCTGGAGGACCCGCGGGTACGCGAGGCGGTGGCCGCGGCCCAGGCCGCCTGCGTCACCCTGCGGGTGCT
CGGAAGCTACGGCGTGGTGTGA

Upstream 100 bases:

>100_bases
CACGCCGCCTCCGCAGCGGTGACGGCGGCGCTCGACGACATCCGTCCGCTCACCTCGTCGCTGCGCGTGCTGGGGACGTA
TGCGCGCGCGGAGTCGCCTC

Downstream 100 bases:

>100_bases
GGCTCGCTCAGGCGCCGGTGGCCTGGAGCCCGTCGCCGCTCTGCACGGCCGTCTCGTACGCGGAGCGCACCAGTTGGACG
TAGCGCTGCAGTGCGGGGAG

Product: prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MPESPRRIAFQGEPGAYGEEALRALHGADVEAVPCLTFRAVFEAVAEGRVHGGVVPVESSLGGPVAETVDLLLEHDVPAT
GELSLRIRHCLLAPPGLSLDDVQQALSHPQALAQCAGYLRRRGISPLPEANTAIAARKVAEEKPPHTAAIASRMSADLYG
LAVLEEGVEDSPDNFTRFIALGTAPERTWTRRKTALAFTVENGPGALFRVMSAFSSRGLNVARLESRPQRRAWEYVWCLD
VDGALEDPRVREAVAAAQAACVTLRVLGSYGVV

Sequences:

>Translated_273_residues
MPESPRRIAFQGEPGAYGEEALRALHGADVEAVPCLTFRAVFEAVAEGRVHGGVVPVESSLGGPVAETVDLLLEHDVPAT
GELSLRIRHCLLAPPGLSLDDVQQALSHPQALAQCAGYLRRRGISPLPEANTAIAARKVAEEKPPHTAAIASRMSADLYG
LAVLEEGVEDSPDNFTRFIALGTAPERTWTRRKTALAFTVENGPGALFRVMSAFSSRGLNVARLESRPQRRAWEYVWCLD
VDGALEDPRVREAVAAAQAACVTLRVLGSYGVV
>Mature_272_residues
PESPRRIAFQGEPGAYGEEALRALHGADVEAVPCLTFRAVFEAVAEGRVHGGVVPVESSLGGPVAETVDLLLEHDVPATG
ELSLRIRHCLLAPPGLSLDDVQQALSHPQALAQCAGYLRRRGISPLPEANTAIAARKVAEEKPPHTAAIASRMSADLYGL
AVLEEGVEDSPDNFTRFIALGTAPERTWTRRKTALAFTVENGPGALFRVMSAFSSRGLNVARLESRPQRRAWEYVWCLDV
DGALEDPRVREAVAAAQAACVTLRVLGSYGVV

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=271, Percent_Identity=32.8413284132841, Blast_Score=137, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6324013, Length=306, Percent_Identity=25.4901960784314, Blast_Score=84, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 29253; Mature: 29121

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS00857 PREPHENATE_DEHYDR_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPESPRRIAFQGEPGAYGEEALRALHGADVEAVPCLTFRAVFEAVAEGRVHGGVVPVESS
CCCCCCEEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCC
LGGPVAETVDLLLEHDVPATGELSLRIRHCLLAPPGLSLDDVQQALSHPQALAQCAGYLR
CCCHHHHHHHHHHHCCCCCCCCHHEEEEEHEECCCCCCHHHHHHHHHCHHHHHHHHHHHH
RRGISPLPEANTAIAARKVAEEKPPHTAAIASRMSADLYGLAVLEEGVEDSPDNFTRFIA
HCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEE
LGTAPERTWTRRKTALAFTVENGPGALFRVMSAFSSRGLNVARLESRPQRRAWEYVWCLD
ECCCCCHHHHHHHEEEEEEEECCCHHHHHHHHHHHHCCCEEEHHHCCCHHCCEEEEEEEE
VDGALEDPRVREAVAAAQAACVTLRVLGSYGVV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PESPRRIAFQGEPGAYGEEALRALHGADVEAVPCLTFRAVFEAVAEGRVHGGVVPVESS
CCCCCEEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCC
LGGPVAETVDLLLEHDVPATGELSLRIRHCLLAPPGLSLDDVQQALSHPQALAQCAGYLR
CCCHHHHHHHHHHHCCCCCCCCHHEEEEEHEECCCCCCHHHHHHHHHCHHHHHHHHHHHH
RRGISPLPEANTAIAARKVAEEKPPHTAAIASRMSADLYGLAVLEEGVEDSPDNFTRFIA
HCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEE
LGTAPERTWTRRKTALAFTVENGPGALFRVMSAFSSRGLNVARLESRPQRRAWEYVWCLD
ECCCCCHHHHHHHEEEEEEEECCCHHHHHHHHHHHHCCCEEEHHHCCCHHCCEEEEEEEE
VDGALEDPRVREAVAAAQAACVTLRVLGSYGVV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]