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The map label for this gene is pheA [H]

Identifier: 108760492

GI number: 108760492

Start: 3772815

End: 3773954

Strand: Reverse

Name: pheA [H]

Synonym: MXAN_3221

Alternate gene names: 108760492

Gene position: 3773954-3772815 (Counterclockwise)

Preceding gene: 108757267

Following gene: 108763520

Centisome position: 41.29

GC content: 72.72

Gene sequence:

>1140_bases
ATGACCACCCTCCCCGACCTCGACCTCATCCGGACCTCCATCGAGCGCATCGACGAGGAGATCCTCGATGCCCTCCGCCG
CCGGATGGCGCTGGCGGACGACGTCGCCCGGGCGAAGCTGGCCGCCGCCGCGCCCTTCCGGGACCAGCGCCGCGAGGACC
TGCTCCTGCGCCGCATCCGCACCCGCGCCGCGGAGCACGGCCTGGACCCGCACGAGGTGGAGCGCATCTGGCGGCTCTTC
ATCGACATGTCCGTGGCTCGGCAACACGAGCTCGTCACCCGCCTGGACACCACGCCCCTGCGCGTGGCCTACCCCGGCGT
GGAGGGCTCCTACAGCCACCTGGCCGCGCGCCGCCGCTATGGGCACCGCGCGGGCGGCGTGCTGCTGTCCGGCTTCGACC
ATGCGCGAGAGGCCGTGGAGGCGCTCCGCCGCGGCGAGCAGGACCTGGTGCTGCTGCCCATCGAGAACACCACCGCGGGC
AGCATGAACGAGACGTATGACCTGCTCGCCGAGGGCGGCGTGGTCATCACCGCAGAGCTGGTCAGCCAGGTGGACCACCG
CCTGCTGGGCCTGCCGGGCGCGAAGCTGGAAGGCCTGCGGGAGGTGCTGTCTCATCCGCAGGCGCTGGCGCAGTGCGAGA
CGTTCCTCCGGGAGAAGGTGCCCTGGGCCCGCGCGGTGCCGGACGTGGACACCGGCGGCGCGGCGCAGAAGGTCCGCGAG
CGCAACGACGCGTCGGTGGCGGCCATCGCCAGCGAGACGGCGGCGCAGCGCTTCGGCCTGGAGGTGCTCGCGGGCGATTT
GCAGCCGGCCTTCGACTACACGCGCTTCGTGGAGGTGGGCCGTGAGGCCTCGCCCCTGGCGCCCGGCGTGCCGTGCAAGA
CGTCCCTGCTGGTGGTGCTGGAGCACAAGCCCGGCACGTTGGGAGAGATGCTCCAGCGGCTCACCCTGCGCGGCGTGAAC
CTGAGCAAGCTGGAGTCGCGCCCCATCCCGGGGCAGCCGTGGCAGTACCGCTTCTACCTGGACGTGGAGGGCCACGCCGC
CTCCGCAGCGGTGACGGCGGCGCTCGACGACATCCGTCCGCTCACCTCGTCGCTGCGCGTGCTGGGGACGTATGCGCGCG
CGGAGTCGCCTCATGCCTGA

Upstream 100 bases:

>100_bases
GGTTCTATCGTGCGCAGGGCTTCGCCCAGCGAGGCGAGCCCTTCGACCTGCCCGGCATCGGCCCGCACCACCTCATGTGG
CGCAACCTCGGAACCTCGTG

Downstream 100 bases:

>100_bases
GTCGCCGCGTCGCATCGCCTTCCAGGGCGAGCCTGGCGCCTACGGAGAAGAGGCCCTGCGCGCGCTGCATGGCGCCGACG
TGGAGGCCGTCCCCTGCCTC

Product: chorismate mutase/prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 379; Mature: 378

Protein sequence:

>379_residues
MTTLPDLDLIRTSIERIDEEILDALRRRMALADDVARAKLAAAAPFRDQRREDLLLRRIRTRAAEHGLDPHEVERIWRLF
IDMSVARQHELVTRLDTTPLRVAYPGVEGSYSHLAARRRYGHRAGGVLLSGFDHAREAVEALRRGEQDLVLLPIENTTAG
SMNETYDLLAEGGVVITAELVSQVDHRLLGLPGAKLEGLREVLSHPQALAQCETFLREKVPWARAVPDVDTGGAAQKVRE
RNDASVAAIASETAAQRFGLEVLAGDLQPAFDYTRFVEVGREASPLAPGVPCKTSLLVVLEHKPGTLGEMLQRLTLRGVN
LSKLESRPIPGQPWQYRFYLDVEGHAASAAVTAALDDIRPLTSSLRVLGTYARAESPHA

Sequences:

>Translated_379_residues
MTTLPDLDLIRTSIERIDEEILDALRRRMALADDVARAKLAAAAPFRDQRREDLLLRRIRTRAAEHGLDPHEVERIWRLF
IDMSVARQHELVTRLDTTPLRVAYPGVEGSYSHLAARRRYGHRAGGVLLSGFDHAREAVEALRRGEQDLVLLPIENTTAG
SMNETYDLLAEGGVVITAELVSQVDHRLLGLPGAKLEGLREVLSHPQALAQCETFLREKVPWARAVPDVDTGGAAQKVRE
RNDASVAAIASETAAQRFGLEVLAGDLQPAFDYTRFVEVGREASPLAPGVPCKTSLLVVLEHKPGTLGEMLQRLTLRGVN
LSKLESRPIPGQPWQYRFYLDVEGHAASAAVTAALDDIRPLTSSLRVLGTYARAESPHA
>Mature_378_residues
TTLPDLDLIRTSIERIDEEILDALRRRMALADDVARAKLAAAAPFRDQRREDLLLRRIRTRAAEHGLDPHEVERIWRLFI
DMSVARQHELVTRLDTTPLRVAYPGVEGSYSHLAARRRYGHRAGGVLLSGFDHAREAVEALRRGEQDLVLLPIENTTAGS
MNETYDLLAEGGVVITAELVSQVDHRLLGLPGAKLEGLREVLSHPQALAQCETFLREKVPWARAVPDVDTGGAAQKVRER
NDASVAAIASETAAQRFGLEVLAGDLQPAFDYTRFVEVGREASPLAPGVPCKTSLLVVLEHKPGTLGEMLQRLTLRGVNL
SKLESRPIPGQPWQYRFYLDVEGHAASAAVTAALDDIRPLTSSLRVLGTYARAESPHA

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=381, Percent_Identity=36.4829396325459, Blast_Score=219, Evalue=3e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010952
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 41778; Mature: 41647

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLPDLDLIRTSIERIDEEILDALRRRMALADDVARAKLAAAAPFRDQRREDLLLRRIR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
TRAAEHGLDPHEVERIWRLFIDMSVARQHELVTRLDTTPLRVAYPGVEGSYSHLAARRRY
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHC
GHRAGGVLLSGFDHAREAVEALRRGEQDLVLLPIENTTAGSMNETYDLLAEGGVVITAEL
CCHHCCEEECCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHCCCEEEEHHH
VSQVDHRLLGLPGAKLEGLREVLSHPQALAQCETFLREKVPWARAVPDVDTGGAAQKVRE
HHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHH
RNDASVAAIASETAAQRFGLEVLAGDLQPAFDYTRFVEVGREASPLAPGVPCKTSLLVVL
CCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEE
EHKPGTLGEMLQRLTLRGVNLSKLESRPIPGQPWQYRFYLDVEGHAASAAVTAALDDIRP
ECCCCCHHHHHHHHHHCCCCHHHHCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHH
LTSSLRVLGTYARAESPHA
HHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TTLPDLDLIRTSIERIDEEILDALRRRMALADDVARAKLAAAAPFRDQRREDLLLRRIR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
TRAAEHGLDPHEVERIWRLFIDMSVARQHELVTRLDTTPLRVAYPGVEGSYSHLAARRRY
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHC
GHRAGGVLLSGFDHAREAVEALRRGEQDLVLLPIENTTAGSMNETYDLLAEGGVVITAEL
CCHHCCEEECCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHCCCEEEEHHH
VSQVDHRLLGLPGAKLEGLREVLSHPQALAQCETFLREKVPWARAVPDVDTGGAAQKVRE
HHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHH
RNDASVAAIASETAAQRFGLEVLAGDLQPAFDYTRFVEVGREASPLAPGVPCKTSLLVVL
CCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEE
EHKPGTLGEMLQRLTLRGVNLSKLESRPIPGQPWQYRFYLDVEGHAASAAVTAALDDIRP
ECCCCCHHHHHHHHHHCCCCHHHHCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHH
LTSSLRVLGTYARAESPHA
HHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1512561; 1444388 [H]