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The map label for this gene is gstA [H]

Identifier: 108763419

GI number: 108763419

Start: 1679174

End: 1679800

Strand: Direct

Name: gstA [H]

Synonym: MXAN_1427

Alternate gene names: 108763419

Gene position: 1679174-1679800 (Clockwise)

Preceding gene: 108760063

Following gene: 108763692

Centisome position: 18.37

GC content: 66.51

Gene sequence:

>627_bases
ATGAAGGTGTACGGCCTCCCGATGAGCACTGCCACGCGTTCGGTCCTCACCACCCTGGCGGAGAAGGGCCAGGAGGCGGA
ACTCGTCGTCGTCGACCTCACGAAGGGGGAGCAGAAGAGCCCCGCGTACATGGAGCACCACCCCTTCGGCGTCATCCCCG
CCTTCGAGGACGATGACGGCTTCAAGCTCTACGAGTCGCGCGCCATCATCCGCTATCTGGACCGCAAGCTGCCGGGGCCC
TCGCTGACGCCGTCCGACGTGCATGCGTACGCGCGCATGGAGCAGTTCATCAGCGTGGAGCAGTGTTACTTCTCGCCCTC
CGCGATGAAGGTCATCTGGGAGCGCCTCTTCAAGAAGGTGATGGGCGGCGGCACGCCGGACGAGGCGCGCATCAGCGAGG
GCCTGCAGGGCGTCGAGCGCGTCTTCGGCATCATCGAGCCGGTGCTGGGCAAGCAGCAGTACCTGGCGGGAGACGGCTTC
TCGCTCGCCGAGGTGACGTGGATGCCCTACATGGATTTCTTCGTCGCCGCGGGCGGCGCGGAGCTCGTCGGTAAGTACCC
GAACGTGGCGGCCTGGTGGGAGCGCGTCCGGAGCCGTCCTTCGTGGAAGAAGGTCACCGGGGCCTGA

Upstream 100 bases:

>100_bases
GCCACTTTCCTGAATTCCTTGCGGCGCTGGCGGCGGCCATGAAGAGTCTGGCCCCGCCTGGCCGGGACTTTCCCCGGCCC
GCCACGCAGAGGAATGTCCC

Downstream 100 bases:

>100_bases
GCCCCGAAGTGACCTCCTGACACTCCGGGTTCCGTCCCACGGCGGGACCCGGTGGGGAATGTCAGACCCTTCGCGCACTG
TGGACCCCGGTAGCAGGACG

Product: putative glutathione S-transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MKVYGLPMSTATRSVLTTLAEKGQEAELVVVDLTKGEQKSPAYMEHHPFGVIPAFEDDDGFKLYESRAIIRYLDRKLPGP
SLTPSDVHAYARMEQFISVEQCYFSPSAMKVIWERLFKKVMGGGTPDEARISEGLQGVERVFGIIEPVLGKQQYLAGDGF
SLAEVTWMPYMDFFVAAGGAELVGKYPNVAAWWERVRSRPSWKKVTGA

Sequences:

>Translated_208_residues
MKVYGLPMSTATRSVLTTLAEKGQEAELVVVDLTKGEQKSPAYMEHHPFGVIPAFEDDDGFKLYESRAIIRYLDRKLPGP
SLTPSDVHAYARMEQFISVEQCYFSPSAMKVIWERLFKKVMGGGTPDEARISEGLQGVERVFGIIEPVLGKQQYLAGDGF
SLAEVTWMPYMDFFVAAGGAELVGKYPNVAAWWERVRSRPSWKKVTGA
>Mature_208_residues
MKVYGLPMSTATRSVLTTLAEKGQEAELVVVDLTKGEQKSPAYMEHHPFGVIPAFEDDDGFKLYESRAIIRYLDRKLPGP
SLTPSDVHAYARMEQFISVEQCYFSPSAMKVIWERLFKKVMGGGTPDEARISEGLQGVERVFGIIEPVLGKQQYLAGDGF
SLAEVTWMPYMDFFVAAGGAELVGKYPNVAAWWERVRSRPSWKKVTGA

Specific function: Forms An Equimolar Complex With The RNA Polymerase Holoenzyme (Rnap) But Not With The Core Enzyme. It Is Synthesized Predominantly When Cells Are Exposed To Amino Acid Starvation, At Which Time It Accounts For Over 50% Of The Total Protein Synthesized. It

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI167466164, Length=200, Percent_Identity=27.5, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI4504187, Length=198, Percent_Identity=29.7979797979798, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI124249394, Length=198, Percent_Identity=29.7979797979798, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17864598, Length=207, Percent_Identity=29.4685990338164, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24654979, Length=211, Percent_Identity=28.9099526066351, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24654975, Length=216, Percent_Identity=27.7777777777778, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI28571670, Length=184, Percent_Identity=28.804347826087, Blast_Score=77, Evalue=7e-15,
Organism=Drosophila melanogaster, GI19922532, Length=211, Percent_Identity=28.436018957346, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24646249, Length=207, Percent_Identity=29.4685990338164, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI19922526, Length=207, Percent_Identity=28.0193236714976, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24646251, Length=206, Percent_Identity=28.6407766990291, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI20130115, Length=211, Percent_Identity=28.436018957346, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI17864592, Length=204, Percent_Identity=26.4705882352941, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17864594, Length=204, Percent_Identity=26.9607843137255, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24654983, Length=209, Percent_Identity=26.3157894736842, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI85725204, Length=203, Percent_Identity=28.0788177339901, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI17737923, Length=203, Percent_Identity=28.0788177339901, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24654996, Length=208, Percent_Identity=25, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17864596, Length=208, Percent_Identity=26.4423076923077, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI19922528, Length=203, Percent_Identity=25.1231527093596, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI17933730, Length=207, Percent_Identity=24.6376811594203, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24654992, Length=211, Percent_Identity=25.5924170616114, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45549270, Length=206, Percent_Identity=24.7572815533981, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1982 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: NA

Molecular weight: Translated: 23234; Mature: 23234

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVYGLPMSTATRSVLTTLAEKGQEAELVVVDLTKGEQKSPAYMEHHPFGVIPAFEDDDG
CEEECCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCEECCCCCCCCC
FKLYESRAIIRYLDRKLPGPSLTPSDVHAYARMEQFISVEQCYFSPSAMKVIWERLFKKV
CCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
MGGGTPDEARISEGLQGVERVFGIIEPVLGKQQYLAGDGFSLAEVTWMPYMDFFVAAGGA
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCH
ELVGKYPNVAAWWERVRSRPSWKKVTGA
HHHCCCCCHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKVYGLPMSTATRSVLTTLAEKGQEAELVVVDLTKGEQKSPAYMEHHPFGVIPAFEDDDG
CEEECCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCEECCCCCCCCC
FKLYESRAIIRYLDRKLPGPSLTPSDVHAYARMEQFISVEQCYFSPSAMKVIWERLFKKV
CCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
MGGGTPDEARISEGLQGVERVFGIIEPVLGKQQYLAGDGFSLAEVTWMPYMDFFVAAGGA
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCH
ELVGKYPNVAAWWERVRSRPSWKKVTGA
HHHCCCCCHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA