Click here to switch to the map view.

The map label for this gene is era [H]

Identifier: 108763403

GI number: 108763403

Start: 4482267

End: 4483211

Strand: Direct

Name: era [H]

Synonym: MXAN_3765

Alternate gene names: 108763403

Gene position: 4482267-4483211 (Clockwise)

Preceding gene: 108760484

Following gene: 108759687

Centisome position: 49.04

GC content: 66.46

Gene sequence:

>945_bases
ATGGCCCCCCCCAAGACACACCGCAGCGGCTTCGCCGCTCTCATCGGGCGCCCCAACGTGGGCAAGAGCACGCTGCTCAA
TGCACTGACGGGCGAAAAAATCGCCATCGTCTCCCCCAAGCCCCAGACGACGCGCAACCGCATCCTCGGCGTCGTCACCC
GTCCGGAAGGACAGGTGGCGTTCATCGACACGCCGGGCATCCACCAGGCCAAGGGCGAGCTGAACCGCTACATGGTCGAG
GTGGCGCTCCAGGCGGCGGAGGAGGTGGACCTGGTCCTCTTCCTCATCGAGCCGCCAGCGAGCGAGAAGCCCGAGGTGAG
CCCGGGCAACCGCGCCATCCTCGACCGGCTGCAGAAGATCGGCAAACCGACCTTCCTGGTCATCAACAAGATCGATAGCG
TCCCCAAGTCGCAGCTCCTGCCGCTCATCGACCTGTACCGCCAGGAGTTCCCCTTCGCGGAGGTGGTCCCCATCTCCGCC
CGGGAGAAGGACGGCGTGGAGCGGCTGTTCCACACCGTCCTGGGACACCTGCCGGAAGGCGAGAACGTCTTCGACGAGGA
TATGCTCACCGACCAGCAGGAGCGCGCGCTGGTGGCCGAGTACATCCGCGAGCAGGTGCTGCGGCACTGCCGCCAGGAGA
TTCCGTACTCCACGGCCGTGGTGGTGGACATCTTCGACGAATCCGAGCGCGAGCCCCGGCCGGGCACGCCGCCGAACCAA
CTGGGCGGGCTCATTCGCATCGCCGCGTCCATCTTCGTGGAGCGCGACAGCCAGAAGGCCATCATCATCGGCAAGCAGGG
GCAGATGCTGAAGACCATTGGCACTGACGCGCGCAAGTCCGTGCAGCGGTTGCTGGGCGCGCATGTGTACCTGGACCTTC
GCGTCCGCGTGGAGCCGCGCTGGAGCGAGCGCCCCGAAGGCCTCAAGAAGCTGGGATACGACTGA

Upstream 100 bases:

>100_bases
CTGGCATGACCGGGCGGGCGGTGGGTTGTTATAGGCGCTGTCCAGACGTTCCCTTTTCGGGCCTCCGCGGTACGCGGCGT
CCCAGATCACCTCCGAAGCA

Downstream 100 bases:

>100_bases
AATGAAGCCCCTGGTCGCAATTGTCGGACGCCCCAACGTGGGCAAGAGCACGCTGTTCAATCGGCTGGTGGGCCGGCGCA
TCGCGCTGGTGCAGGACGAG

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MAPPKTHRSGFAALIGRPNVGKSTLLNALTGEKIAIVSPKPQTTRNRILGVVTRPEGQVAFIDTPGIHQAKGELNRYMVE
VALQAAEEVDLVLFLIEPPASEKPEVSPGNRAILDRLQKIGKPTFLVINKIDSVPKSQLLPLIDLYRQEFPFAEVVPISA
REKDGVERLFHTVLGHLPEGENVFDEDMLTDQQERALVAEYIREQVLRHCRQEIPYSTAVVVDIFDESEREPRPGTPPNQ
LGGLIRIAASIFVERDSQKAIIIGKQGQMLKTIGTDARKSVQRLLGAHVYLDLRVRVEPRWSERPEGLKKLGYD

Sequences:

>Translated_314_residues
MAPPKTHRSGFAALIGRPNVGKSTLLNALTGEKIAIVSPKPQTTRNRILGVVTRPEGQVAFIDTPGIHQAKGELNRYMVE
VALQAAEEVDLVLFLIEPPASEKPEVSPGNRAILDRLQKIGKPTFLVINKIDSVPKSQLLPLIDLYRQEFPFAEVVPISA
REKDGVERLFHTVLGHLPEGENVFDEDMLTDQQERALVAEYIREQVLRHCRQEIPYSTAVVVDIFDESEREPRPGTPPNQ
LGGLIRIAASIFVERDSQKAIIIGKQGQMLKTIGTDARKSVQRLLGAHVYLDLRVRVEPRWSERPEGLKKLGYD
>Mature_313_residues
APPKTHRSGFAALIGRPNVGKSTLLNALTGEKIAIVSPKPQTTRNRILGVVTRPEGQVAFIDTPGIHQAKGELNRYMVEV
ALQAAEEVDLVLFLIEPPASEKPEVSPGNRAILDRLQKIGKPTFLVINKIDSVPKSQLLPLIDLYRQEFPFAEVVPISAR
EKDGVERLFHTVLGHLPEGENVFDEDMLTDQQERALVAEYIREQVLRHCRQEIPYSTAVVVDIFDESEREPRPGTPPNQL
GGLIRIAASIFVERDSQKAIIIGKQGQMLKTIGTDARKSVQRLLGAHVYLDLRVRVEPRWSERPEGLKKLGYD

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=343, Percent_Identity=26.530612244898, Blast_Score=93, Evalue=4e-19,
Organism=Escherichia coli, GI1788919, Length=315, Percent_Identity=38.7301587301587, Blast_Score=216, Evalue=1e-57,
Organism=Escherichia coli, GI87082120, Length=189, Percent_Identity=38.0952380952381, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI2367268, Length=183, Percent_Identity=31.6939890710383, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323665, Length=177, Percent_Identity=28.8135593220339, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24646434, Length=260, Percent_Identity=26.1538461538462, Blast_Score=87, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 35050; Mature: 34919

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPPKTHRSGFAALIGRPNVGKSTLLNALTGEKIAIVSPKPQTTRNRILGVVTRPEGQVA
CCCCCCCCCCCEEEECCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCEEEEEECCCCCEE
FIDTPGIHQAKGELNRYMVEVALQAAEEVDLVLFLIEPPASEKPEVSPGNRAILDRLQKI
EEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHH
GKPTFLVINKIDSVPKSQLLPLIDLYRQEFPFAEVVPISAREKDGVERLFHTVLGHLPEG
CCCEEEEEECCCCCCHHHCCHHHHHHHHHCCCHHEEECCCCCHHHHHHHHHHHHHCCCCC
ENVFDEDMLTDQQERALVAEYIREQVLRHCRQEIPYSTAVVVDIFDESEREPRPGTPPNQ
CCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCHHH
LGGLIRIAASIFVERDSQKAIIIGKQGQMLKTIGTDARKSVQRLLGAHVYLDLRVRVEPR
HHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHCCHHHHHHHHHHCCEEEEEEEEEECCC
WSERPEGLKKLGYD
CCCCCHHHHHCCCC
>Mature Secondary Structure 
APPKTHRSGFAALIGRPNVGKSTLLNALTGEKIAIVSPKPQTTRNRILGVVTRPEGQVA
CCCCCCCCCCEEEECCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCEEEEEECCCCCEE
FIDTPGIHQAKGELNRYMVEVALQAAEEVDLVLFLIEPPASEKPEVSPGNRAILDRLQKI
EEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHH
GKPTFLVINKIDSVPKSQLLPLIDLYRQEFPFAEVVPISAREKDGVERLFHTVLGHLPEG
CCCEEEEEECCCCCCHHHCCHHHHHHHHHCCCHHEEECCCCCHHHHHHHHHHHHHCCCCC
ENVFDEDMLTDQQERALVAEYIREQVLRHCRQEIPYSTAVVVDIFDESEREPRPGTPPNQ
CCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCHHH
LGGLIRIAASIFVERDSQKAIIIGKQGQMLKTIGTDARKSVQRLLGAHVYLDLRVRVEPR
HHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHCCHHHHHHHHHHCCEEEEEEEEEECCC
WSERPEGLKKLGYD
CCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA