BacMap

Definition	Myxococcus xanthus DK 1622 chromosome, complete genome.
Accession	NC_008095
Length	9,139,763

Click here to switch to the map view.

The map label for this gene is cypB [H]

Identifier: 108760484

GI number: 108760484

Start: 4481549

End: 4482145

Strand: Direct

Name: cypB [H]

Synonym: MXAN_3764

Alternate gene names: 108760484

Gene position: 4481549-4482145 (Clockwise)

Preceding gene: 108761539

Following gene: 108763403

Centisome position: 49.03

GC content: 64.99

Gene sequence:

>597_bases
ATGACCGGGTTCGTCCTCGGACGGGCCCCCACACGGGAGGGTAGCATGGGATTGTTGGACGAGGCCCGCGCGGGCAATGA
CCTTTACGCCACCTTCGACACCACGCAGGGGCAGATCGTGGTGAAGCTGTTCGCGAAGGATGCGCCGAAGACGGTGAGCA
GCTTCGTGGGCCTGGCGACGGGCGAGCTGCCCTTCCAGGACCCGAAGACGGGTGAGAAGACGCAGCGCCCGTACTACGAC
GGCATCATCTTCCACCGCGTGATTCCGGGCTTCATGATTCAGGGCGGTGACCCCACGGGCACCGGCCGCGGCGGCCCGGG
CTTCAACGTGGACGACGAGTACCAGAGCGGCCGGACCTTCGACAAAGTGGGTCTGCTGGCCACGGCGAACATCGGCCGCC
CCAACACCAACGGCAGCCAGTTCTTCATCACCACGTCCAAGCCGACCTACCTCAACAACAAGCACACCATCTTCGGTGAG
GTGCTCAGCGGCTACGATGTGGTGGAGAAGATCGCCGGCGTTCCGCGCGACGGGGATGACCGCCCCCGCCAGCCCGTGGT
CATCAACAAGCTGACCATTTCGACGACCCAGCCGTAG

Upstream 100 bases:

>100_bases
CGACAAGGCTCCCGCGGGCGTGACGGCCCCCGCGGCGAGCAAGGGAGCGGCGCCCAAGAAGGACGCGGGCGCGAAGACGG
TTTCACCAAGGCCGTGACAC

Downstream 100 bases:

>100_bases
CCTGTCCGATCGCCGCCCGTCCTGGCATGACCGGGCGGGCGGTGGGTTGTTATAGGCGCTGTCCAGACGTTCCCTTTTCG
GGCCTCCGCGGTACGCGGCG

Product: cyclophilin-type peptidylprolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase B; Cyclophilin ScCypB; Rotamase B; S-cyclophilin [H]

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MTGFVLGRAPTREGSMGLLDEARAGNDLYATFDTTQGQIVVKLFAKDAPKTVSSFVGLATGELPFQDPKTGEKTQRPYYD
GIIFHRVIPGFMIQGGDPTGTGRGGPGFNVDDEYQSGRTFDKVGLLATANIGRPNTNGSQFFITTSKPTYLNNKHTIFGE
VLSGYDVVEKIAGVPRDGDDRPRQPVVINKLTISTTQP

Sequences:

>Translated_198_residues
MTGFVLGRAPTREGSMGLLDEARAGNDLYATFDTTQGQIVVKLFAKDAPKTVSSFVGLATGELPFQDPKTGEKTQRPYYD
GIIFHRVIPGFMIQGGDPTGTGRGGPGFNVDDEYQSGRTFDKVGLLATANIGRPNTNGSQFFITTSKPTYLNNKHTIFGE
VLSGYDVVEKIAGVPRDGDDRPRQPVVINKLTISTTQP
>Mature_197_residues
TGFVLGRAPTREGSMGLLDEARAGNDLYATFDTTQGQIVVKLFAKDAPKTVSSFVGLATGELPFQDPKTGEKTQRPYYDG
IIFHRVIPGFMIQGGDPTGTGRGGPGFNVDDEYQSGRTFDKVGLLATANIGRPNTNGSQFFITTSKPTYLNNKHTIFGEV
LSGYDVVEKIAGVPRDGDDRPRQPVVINKLTISTTQP

Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]

COG id: COG0652

COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase cyclophilin-type domain [H]

Homologues:

Organism=Homo sapiens, GI7706339, Length=162, Percent_Identity=44.4444444444444, Blast_Score=124, Evalue=8e-29,
Organism=Homo sapiens, GI64276486, Length=165, Percent_Identity=41.8181818181818, Blast_Score=122, Evalue=2e-28,
Organism=Homo sapiens, GI24308049, Length=168, Percent_Identity=41.6666666666667, Blast_Score=116, Evalue=1e-26,
Organism=Homo sapiens, GI19557636, Length=170, Percent_Identity=38.8235294117647, Blast_Score=112, Evalue=2e-25,
Organism=Homo sapiens, GI4505991, Length=171, Percent_Identity=43.859649122807, Blast_Score=111, Evalue=5e-25,
Organism=Homo sapiens, GI4758950, Length=160, Percent_Identity=43.75, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI42560244, Length=158, Percent_Identity=41.7721518987342, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI256017253, Length=137, Percent_Identity=45.2554744525547, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI221139811, Length=137, Percent_Identity=45.2554744525547, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI256017251, Length=137, Percent_Identity=45.2554744525547, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI4826932, Length=157, Percent_Identity=42.6751592356688, Blast_Score=98, Evalue=4e-21,
Organism=Homo sapiens, GI178057341, Length=139, Percent_Identity=44.6043165467626, Blast_Score=98, Evalue=5e-21,
Organism=Homo sapiens, GI5454154, Length=161, Percent_Identity=39.7515527950311, Blast_Score=97, Evalue=7e-21,
Organism=Homo sapiens, GI6631100, Length=151, Percent_Identity=41.0596026490066, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI209417936, Length=139, Percent_Identity=43.8848920863309, Blast_Score=94, Evalue=9e-20,
Organism=Homo sapiens, GI30102944, Length=139, Percent_Identity=43.8848920863309, Blast_Score=94, Evalue=9e-20,
Organism=Homo sapiens, GI219842199, Length=139, Percent_Identity=43.8848920863309, Blast_Score=94, Evalue=9e-20,
Organism=Homo sapiens, GI10863927, Length=139, Percent_Identity=41.726618705036, Blast_Score=94, Evalue=9e-20,
Organism=Homo sapiens, GI5031987, Length=138, Percent_Identity=44.2028985507246, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI310129267, Length=143, Percent_Identity=41.2587412587413, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI310120620, Length=143, Percent_Identity=41.2587412587413, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI22547212, Length=169, Percent_Identity=39.0532544378698, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI7657473, Length=169, Percent_Identity=39.0532544378698, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI310110104, Length=157, Percent_Identity=37.5796178343949, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI22547215, Length=169, Percent_Identity=39.0532544378698, Blast_Score=91, Evalue=6e-19,
Organism=Homo sapiens, GI5174637, Length=195, Percent_Identity=36.4102564102564, Blast_Score=89, Evalue=2e-18,
Organism=Homo sapiens, GI169163387, Length=139, Percent_Identity=41.0071942446043, Blast_Score=88, Evalue=5e-18,
Organism=Homo sapiens, GI169164185, Length=139, Percent_Identity=40.2877697841727, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI169163623, Length=139, Percent_Identity=40.2877697841727, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI310127646, Length=138, Percent_Identity=39.1304347826087, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI310114371, Length=138, Percent_Identity=39.1304347826087, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI310119221, Length=138, Percent_Identity=39.1304347826087, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI303305009, Length=181, Percent_Identity=35.9116022099448, Blast_Score=85, Evalue=4e-17,
Organism=Homo sapiens, GI45439316, Length=177, Percent_Identity=36.1581920903955, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI150418007, Length=147, Percent_Identity=40.1360544217687, Blast_Score=80, Evalue=8e-16,
Organism=Homo sapiens, GI20911035, Length=173, Percent_Identity=31.7919075144509, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI310132444, Length=143, Percent_Identity=39.1608391608392, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI310113152, Length=143, Percent_Identity=39.1608391608392, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI169214050, Length=146, Percent_Identity=37.6712328767123, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI239751853, Length=146, Percent_Identity=37.6712328767123, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI113428306, Length=146, Percent_Identity=37.6712328767123, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI27735045, Length=164, Percent_Identity=31.7073170731707, Blast_Score=77, Evalue=9e-15,
Organism=Homo sapiens, GI310114540, Length=131, Percent_Identity=38.9312977099237, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI310127745, Length=131, Percent_Identity=38.9312977099237, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI310119290, Length=131, Percent_Identity=38.9312977099237, Blast_Score=72, Evalue=3e-13,
Organism=Escherichia coli, GI1786736, Length=179, Percent_Identity=34.0782122905028, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1789763, Length=175, Percent_Identity=30.2857142857143, Blast_Score=67, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17539496, Length=165, Percent_Identity=44.2424242424242, Blast_Score=128, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI71980594, Length=169, Percent_Identity=37.2781065088757, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17506311, Length=197, Percent_Identity=37.0558375634518, Blast_Score=114, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI71980590, Length=158, Percent_Identity=37.9746835443038, Blast_Score=113, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI17552784, Length=159, Percent_Identity=42.7672955974843, Blast_Score=108, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17532641, Length=194, Percent_Identity=35.5670103092784, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17552780, Length=156, Percent_Identity=44.2307692307692, Blast_Score=105, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17551282, Length=161, Percent_Identity=41.6149068322981, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17551284, Length=161, Percent_Identity=41.6149068322981, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17506307, Length=156, Percent_Identity=43.5897435897436, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17566266, Length=143, Percent_Identity=43.3566433566434, Blast_Score=97, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17532643, Length=158, Percent_Identity=39.873417721519, Blast_Score=97, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17552782, Length=157, Percent_Identity=42.0382165605096, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17559074, Length=142, Percent_Identity=41.5492957746479, Blast_Score=94, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17539498, Length=179, Percent_Identity=37.4301675977654, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI71997782, Length=169, Percent_Identity=36.094674556213, Blast_Score=91, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17565860, Length=143, Percent_Identity=42.6573426573427, Blast_Score=88, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI32563659, Length=177, Percent_Identity=29.9435028248588, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI115533296, Length=144, Percent_Identity=31.9444444444444, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6321848, Length=160, Percent_Identity=43.75, Blast_Score=103, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6320510, Length=159, Percent_Identity=44.0251572327044, Blast_Score=103, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6320359, Length=140, Percent_Identity=46.4285714285714, Blast_Score=102, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6323562, Length=161, Percent_Identity=42.2360248447205, Blast_Score=98, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6322492, Length=179, Percent_Identity=37.9888268156425, Blast_Score=97, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6323246, Length=164, Percent_Identity=39.0243902439024, Blast_Score=84, Evalue=1e-17,
Organism=Drosophila melanogaster, GI17986117, Length=175, Percent_Identity=41.7142857142857, Blast_Score=130, Evalue=4e-31,
Organism=Drosophila melanogaster, GI19922376, Length=175, Percent_Identity=36, Blast_Score=113, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24650807, Length=156, Percent_Identity=45.5128205128205, Blast_Score=107, Evalue=5e-24,
Organism=Drosophila melanogaster, GI45549139, Length=158, Percent_Identity=41.7721518987342, Blast_Score=102, Evalue=1e-22,
Organism=Drosophila melanogaster, GI20130249, Length=156, Percent_Identity=42.9487179487179, Blast_Score=101, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24586038, Length=179, Percent_Identity=36.8715083798883, Blast_Score=97, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24652460, Length=170, Percent_Identity=33.5294117647059, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24664125, Length=157, Percent_Identity=40.1273885350318, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI21357783, Length=157, Percent_Identity=40.1273885350318, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI17647301, Length=158, Percent_Identity=42.4050632911392, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI19922912, Length=196, Percent_Identity=38.7755102040816, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17136360, Length=160, Percent_Identity=36.875, Blast_Score=87, Evalue=8e-18,
Organism=Drosophila melanogaster, GI21357249, Length=131, Percent_Identity=37.4045801526718, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24661775, Length=158, Percent_Identity=31.0126582278481, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI21355237, Length=158, Percent_Identity=31.0126582278481, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24661771, Length=158, Percent_Identity=31.0126582278481, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI21355677, Length=172, Percent_Identity=29.6511627906977, Blast_Score=67, Evalue=9e-12,

Paralogues:

None

Copy number: 780 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015891
- InterPro:   IPR020892
- InterPro:   IPR002130 [H]

Pfam domain/function: PF00160 Pro_isomerase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 21376; Mature: 21245

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: PS50072 CSA_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGFVLGRAPTREGSMGLLDEARAGNDLYATFDTTQGQIVVKLFAKDAPKTVSSFVGLAT
CCCEEECCCCCCCCCCCCHHHHCCCCCEEEEEECCCCEEEEEEECCCCCHHHHHHHHHCC
GELPFQDPKTGEKTQRPYYDGIIFHRVIPGFMIQGGDPTGTGRGGPGFNVDDEYQSGRTF
CCCCCCCCCCCCCCCCCCCCCCHHHHHCCCEEEECCCCCCCCCCCCCCCCCCHHHCCCCC
DKVGLLATANIGRPNTNGSQFFITTSKPTYLNNKHTIFGEVLSGYDVVEKIAGVPRDGDD
HHEEEEEEECCCCCCCCCCEEEEECCCCCEECCCCEEHHHHHCCHHHHHHHHCCCCCCCC
RPRQPVVINKLTISTTQP
CCCCCEEEEEEEEECCCC
>Mature Secondary Structure 
TGFVLGRAPTREGSMGLLDEARAGNDLYATFDTTQGQIVVKLFAKDAPKTVSSFVGLAT
CCEEECCCCCCCCCCCCHHHHCCCCCEEEEEECCCCEEEEEEECCCCCHHHHHHHHHCC
GELPFQDPKTGEKTQRPYYDGIIFHRVIPGFMIQGGDPTGTGRGGPGFNVDDEYQSGRTF
CCCCCCCCCCCCCCCCCCCCCCHHHHHCCCEEEECCCCCCCCCCCCCCCCCCHHHCCCCC
DKVGLLATANIGRPNTNGSQFFITTSKPTYLNNKHTIFGEVLSGYDVVEKIAGVPRDGDD
HHEEEEEEECCCCCCCCCCEEEEECCCCCEECCCCEEHHHHHCCHHHHHHHHCCCCCCCC
RPRQPVVINKLTISTTQP
CCCCCEEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9025285 [H]