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The map label for this gene is atoC [H]

Identifier: 108763352

GI number: 108763352

Start: 1073217

End: 1074584

Strand: Reverse

Name: atoC [H]

Synonym: MXAN_0937

Alternate gene names: 108763352

Gene position: 1074584-1073217 (Counterclockwise)

Preceding gene: 108757961

Following gene: 108761691

Centisome position: 11.76

GC content: 72.22

Gene sequence:

>1368_bases
ATGCCAGGCCGCGTCCTAGTCGTCGAGGACGAGCGCGAGATGCGCGCGATGTTGGAGAAGGGGCTCACGCGCCGGGGCTT
CACGCCCGTGGCGCTCCCGTCTGCGGACGAGGCCCTGGTGCGGCTGGCCGCCGAGGACTTCGACGTGGTGCTCACCGACC
TGCGCATGCCCGGCATGGACGGGCTGGCGCTGTGCGAGCGCATCGCCCTCAACCGCCCGGACATCCCCGTGGTGGTGGTG
ACGGCCTTCGGCAGCCTGGAGACGGCGGTGGCCGCCATCCGCGCCGGCGCGTACGACTTCGTCACCAAGCCCATCGACGT
GGACGCGCTGGTGCTGGTGCTGGAGCGCGCCGTGCAGCACCGCGCCCTGCGTGAAGAGGTGCGCAGGCTGCGCCAGGAGC
TGGGCCGGCGCGAGGACAGTGGCACTGTGGTGGGTGAGAGCCCCGCCATGAAGCAGGCCTACGCGCTCATCGACCGCGTG
GCGGACCTGGACTCCACGGTGCTGATTACCGGCGAGAGCGGCACCGGCAAGGAGGTGGCGGCCCGCGCCGTCCACACGCG
CGGGCGCCGCAAGGACGGGCCCTTCGTCGCCATCAACTGCGCGGCCATGCCGGAGGCCCTGTTGGAGAGCGAGCTGTTCG
GCCACGCCAAGGGCGCCTTCACCGACGCCAAGGCCGCCCGCACCGGCCTGTTCGTCCAGGCCAACGGCGGCACCCTCTTC
CTGGACGAGGTGGGCGAGCTGCCCCTCACGCTCCAGCCCAAGCTGCTGCGCGCCCTGCAGGAGCGCACGGTGCGCCCGGT
GGGCGGAGACACGGAGCTGCCCTTCGACGCGCGCATCGTCGCCGCCACCAACCGCGACCTGGAGCTGGCCGTGGAGGAGG
ACCGCTTCCGCGAGGACCTCTACTACCGGCTCAACGTCATCGGCGTGGAGCTGCCGCCGCTGCGCGCGCGCGGCAACGAC
GTGCTGGCCCTGTCCCAGCGCTTCATCGAGCAGTTCGCCTCGCGCACCGGGAAGCGGGTGCTGGGCCTGTCCCCCGCGGC
GGCCCAGCGGCTGCTCGCCTACGGCTGGCCGGGCAACGTGCGCGAGCTGCAGAACTGCCTGGAGCGCGCGGTGGCGCTCA
CCTCCTTCGAGGAAATCACCGTGGACGACCTGCCCGAGCGCGTCCGCAACTACAGCCAGCCGCGCGTGGTGCCGGAGACG
CAAGACGCCTCGGAGCTGGTGACGCTGGAGCAGTTGGAGCGGCGCTACATCCACCGCGTTCTGGAGGCGGTGGGCGGAAG
CCGCACGCTGGCGGCGCGCATCCTCGGGGTGGACCGCAAGACGCTGTACCGCAAGCTGGAGCGCGACGACGACACGCGCA
AGGGCTGA

Upstream 100 bases:

>100_bases
CCTATGGGCTCATGTTGGAGCATGACGGCTGGATTGCCGTGCGCAGCGAGCCCGGACGCGGTAGCTGCTTCTCCATCTAC
CTGCCAAGGGGTGAAGACAC

Downstream 100 bases:

>100_bases
CGTCAGTCCACCACGTCCAGACGCACCTCGAAGAGGCGGGGCCACAGCTTGCCCGTCATGAAGATGCGGCCCGAGCCCGG
CTCCACGGCGATGCCGTTGA

Product: sigma-54 dependent DNA-binding response regulator

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MPGRVLVVEDEREMRAMLEKGLTRRGFTPVALPSADEALVRLAAEDFDVVLTDLRMPGMDGLALCERIALNRPDIPVVVV
TAFGSLETAVAAIRAGAYDFVTKPIDVDALVLVLERAVQHRALREEVRRLRQELGRREDSGTVVGESPAMKQAYALIDRV
ADLDSTVLITGESGTGKEVAARAVHTRGRRKDGPFVAINCAAMPEALLESELFGHAKGAFTDAKAARTGLFVQANGGTLF
LDEVGELPLTLQPKLLRALQERTVRPVGGDTELPFDARIVAATNRDLELAVEEDRFREDLYYRLNVIGVELPPLRARGND
VLALSQRFIEQFASRTGKRVLGLSPAAAQRLLAYGWPGNVRELQNCLERAVALTSFEEITVDDLPERVRNYSQPRVVPET
QDASELVTLEQLERRYIHRVLEAVGGSRTLAARILGVDRKTLYRKLERDDDTRKG

Sequences:

>Translated_455_residues
MPGRVLVVEDEREMRAMLEKGLTRRGFTPVALPSADEALVRLAAEDFDVVLTDLRMPGMDGLALCERIALNRPDIPVVVV
TAFGSLETAVAAIRAGAYDFVTKPIDVDALVLVLERAVQHRALREEVRRLRQELGRREDSGTVVGESPAMKQAYALIDRV
ADLDSTVLITGESGTGKEVAARAVHTRGRRKDGPFVAINCAAMPEALLESELFGHAKGAFTDAKAARTGLFVQANGGTLF
LDEVGELPLTLQPKLLRALQERTVRPVGGDTELPFDARIVAATNRDLELAVEEDRFREDLYYRLNVIGVELPPLRARGND
VLALSQRFIEQFASRTGKRVLGLSPAAAQRLLAYGWPGNVRELQNCLERAVALTSFEEITVDDLPERVRNYSQPRVVPET
QDASELVTLEQLERRYIHRVLEAVGGSRTLAARILGVDRKTLYRKLERDDDTRKG
>Mature_454_residues
PGRVLVVEDEREMRAMLEKGLTRRGFTPVALPSADEALVRLAAEDFDVVLTDLRMPGMDGLALCERIALNRPDIPVVVVT
AFGSLETAVAAIRAGAYDFVTKPIDVDALVLVLERAVQHRALREEVRRLRQELGRREDSGTVVGESPAMKQAYALIDRVA
DLDSTVLITGESGTGKEVAARAVHTRGRRKDGPFVAINCAAMPEALLESELFGHAKGAFTDAKAARTGLFVQANGGTLFL
DEVGELPLTLQPKLLRALQERTVRPVGGDTELPFDARIVAATNRDLELAVEEDRFREDLYYRLNVIGVELPPLRARGNDV
LALSQRFIEQFASRTGKRVLGLSPAAAQRLLAYGWPGNVRELQNCLERAVALTSFEEITVDDLPERVRNYSQPRVVPETQ
DASELVTLEQLERRYIHRVLEAVGGSRTLAARILGVDRKTLYRKLERDDDTRKG

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=451, Percent_Identity=45.0110864745011, Blast_Score=389, Evalue=1e-109,
Organism=Escherichia coli, GI1790437, Length=446, Percent_Identity=44.8430493273543, Blast_Score=357, Evalue=1e-99,
Organism=Escherichia coli, GI1790299, Length=465, Percent_Identity=40.6451612903226, Blast_Score=335, Evalue=3e-93,
Organism=Escherichia coli, GI1788905, Length=452, Percent_Identity=42.2566371681416, Blast_Score=324, Evalue=8e-90,
Organism=Escherichia coli, GI87082117, Length=343, Percent_Identity=44.8979591836735, Blast_Score=269, Evalue=2e-73,
Organism=Escherichia coli, GI1789233, Length=320, Percent_Identity=43.75, Blast_Score=251, Evalue=5e-68,
Organism=Escherichia coli, GI1789087, Length=402, Percent_Identity=40.547263681592, Blast_Score=243, Evalue=3e-65,
Organism=Escherichia coli, GI1786524, Length=332, Percent_Identity=41.2650602409639, Blast_Score=228, Evalue=6e-61,
Organism=Escherichia coli, GI87082152, Length=314, Percent_Identity=42.6751592356688, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI1787583, Length=304, Percent_Identity=37.5, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI87081872, Length=248, Percent_Identity=41.9354838709677, Blast_Score=192, Evalue=5e-50,
Organism=Escherichia coli, GI1789828, Length=267, Percent_Identity=37.0786516853933, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI87081858, Length=282, Percent_Identity=31.5602836879433, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1789809, Length=103, Percent_Identity=33.9805825242718, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1786599, Length=114, Percent_Identity=37.719298245614, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 50278; Mature: 50147

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGRVLVVEDEREMRAMLEKGLTRRGFTPVALPSADEALVRLAAEDFDVVLTDLRMPGMD
CCCCEEEEECHHHHHHHHHHCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
GLALCERIALNRPDIPVVVVTAFGSLETAVAAIRAGAYDFVTKPIDVDALVLVLERAVQH
HHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHH
RALREEVRRLRQELGRREDSGTVVGESPAMKQAYALIDRVADLDSTVLITGESGTGKEVA
HHHHHHHHHHHHHHCCCCCCCCEECCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHH
ARAVHTRGRRKDGPFVAINCAAMPEALLESELFGHAKGAFTDAKAARTGLFVQANGGTLF
HHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCEEEEECCCEEE
LDEVGELPLTLQPKLLRALQERTVRPVGGDTELPFDARIVAATNRDLELAVEEDRFREDL
EECCCCCCCEECHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCEEEEECHHHHHHHH
YYRLNVIGVELPPLRARGNDVLALSQRFIEQFASRTGKRVLGLSPAAAQRLLAYGWPGNV
HEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHCCCCCCH
RELQNCLERAVALTSFEEITVDDLPERVRNYSQPRVVPETQDASELVTLEQLERRYIHRV
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LEAVGGSRTLAARILGVDRKTLYRKLERDDDTRKG
HHHHCCCHHHHHHHHCCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PGRVLVVEDEREMRAMLEKGLTRRGFTPVALPSADEALVRLAAEDFDVVLTDLRMPGMD
CCCEEEEECHHHHHHHHHHCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
GLALCERIALNRPDIPVVVVTAFGSLETAVAAIRAGAYDFVTKPIDVDALVLVLERAVQH
HHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHH
RALREEVRRLRQELGRREDSGTVVGESPAMKQAYALIDRVADLDSTVLITGESGTGKEVA
HHHHHHHHHHHHHHCCCCCCCCEECCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHH
ARAVHTRGRRKDGPFVAINCAAMPEALLESELFGHAKGAFTDAKAARTGLFVQANGGTLF
HHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCEEEEECCCEEE
LDEVGELPLTLQPKLLRALQERTVRPVGGDTELPFDARIVAATNRDLELAVEEDRFREDL
EECCCCCCCEECHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCEEEEECHHHHHHHH
YYRLNVIGVELPPLRARGNDVLALSQRFIEQFASRTGKRVLGLSPAAAQRLLAYGWPGNV
HEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHCCCCCCH
RELQNCLERAVALTSFEEITVDDLPERVRNYSQPRVVPETQDASELVTLEQLERRYIHRV
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LEAVGGSRTLAARILGVDRKTLYRKLERDDDTRKG
HHHHCCCHHHHHHHHCCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]