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The map label for this gene is ctaD [H]

Identifier: 108763348

GI number: 108763348

Start: 4645072

End: 4646709

Strand: Reverse

Name: ctaD [H]

Synonym: MXAN_3868

Alternate gene names: 108763348

Gene position: 4646709-4645072 (Counterclockwise)

Preceding gene: 108761189

Following gene: 108757691

Centisome position: 50.84

GC content: 66.48

Gene sequence:

>1638_bases
ATGGCCCCCTCCCACGCTGAGTCCCCCGTGGCGGCGCCCAGCTACCTGGACGCGGAGCGAGGGCTCTGGTCCTGGCTCAC
CACGCGCGACCACAAGCGCATTGGCGTGATGTTCCTGGGCGTGCTGCTGCTGATGTTCCTGTTGGGCGGCGTGTTCGCCC
TGGCCCTGCGCGTGGAGTTGCTGACGCCCGGTGAAACGGTGATGGGGCGGCTGGCCTACAACCGCGCCTTCACCGTGCAC
GGTGTCGTCATGGTGTGGCTCTTCCTCATCCCATCCATCCCCACGGCCTTCGGCAACTTCCTGCTGCCGCTGATGATTGG
CGCCCGGGACGTGGCCTTCCCCCGGCTCAACCTGGCCAGCTTCTACCTCTACGTGCTCGGCGCGGTGATGACGCTGTGGG
GCGTGTTCCAGGGCGGCGTGGACACGGGGTGGACGTTCTACACGCCCTACAGCACCGCCACCGGGCGGGAGGTGATGCCC
GTGCTTCTGGGCGTCTTCGTGGTGGGGTTCTCCACCATCATCACCGGCATCAACTTCATCACCACCGTTCACACCCTGCG
GGCCCCCGGTGTGACGTGGATGAAGGTGCCCCTCTTCGTGTGGGCGATCTACGGCACGTCCATCATCCAGGTGCTCGCGA
CGCCGGTGCTGGGCATGGTGCTGGTGCTCGTGGCGCTGGAGCGGGTGGCGGGCGCGGGGCTGTTCGACCCGAGCCGGGGA
GGGGACCCGCTGCTCTTCCAGCACCTGTTCTGGTTCTACAGCCACCCGGCCGTCTACATCATGGTGCTGCCGGGCATGGG
CGTCATCAGCGAGACGGTGTGCGCCTTCAGCCGCAAGCGCCCCTTCAGCTACCGGGTGATTGTCTGGAGCACGGTGGGCA
TTTCCTTCGTGGGGTTCCTCACCTGGGGACACCACATGTTCGTCTCCGGCCAGTCCACCTTCGGGGCGGGCGCGTTCAGC
GTGCTGTCCATGCTGGTGGCCATCTTCACGGCGATGAAGATCTTCACCTGGCTGGGCACCATGTACCGAGGGAGCCTGTG
GGTCTCCACGCCGTTCACCTACGTCCTTGGCTTCATCTTCCTGCTCTTCTTCGGAGGCATGAGCGGGGTCGCCGTGGCCG
TCACGTCCGCGGACCTGCACTGGCATGACACGTACTTCGTGGTGGCGCACTTCCACTTCATCATGGTGGGCGCGTCGCTG
ATGGCCTTCCTCGCGGCGCTGCATTACTGGTTCCCGAAGATGTGCGGCCGCATGTACCCGGAGGGCATGGGCATCGGGAC
GGCGGTGCTCATCATCTTCGGCTTCATCGCCACCTTCCTGCCTCAGTTCCTGCTGGGCAATCTGGGCATGCCCCGCCGGT
ACGCGGACTACCCGGAGGAGTTCCAGCCGCTGCACGTGGCGTCCACCGCTGGGGCGTCCCTGCTGGGCTTCGGCTTCCTC
ATCGTCGCCATCTACCTGGGCTGGTCGCTGCGGCATGGCCGCGCGGCGGGGCGGAACCCCTGGGGCAGCGAGGGCTATGA
GTGGCTCAGCGACTCACCGCCCCCCGAGTTCAATTTCCATGCGCCGCCTTGGTTTCCCAGGCCGCCCCACGACTACGCGA
ACCCTGGCGCCAACACGGAGGTGGAGCATGCGGCATGA

Upstream 100 bases:

>100_bases
CACGGACGCCTGAGCGCGGGCGAAGTGGGCGCGCTCGTCGAGTTCATCAAGTCGCTTCAGCCGGAACTTCCGGAGCCACC
ATCCTCCCAGGAGCCCACGT

Downstream 100 bases:

>100_bases
GGCGAGCCAGCGCCCGGTGGAGCCCCGTGCCCTCCACTTTGGAGACGAGGCGTCCCGCCAGGACGCCGCGCACCTGGGCA
TGTGGATCTTCCTGGCCACG

Product: cytochrome c oxidase subunit I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I; Oxidase aa(3) subunit 1 [H]

Number of amino acids: Translated: 545; Mature: 544

Protein sequence:

>545_residues
MAPSHAESPVAAPSYLDAERGLWSWLTTRDHKRIGVMFLGVLLLMFLLGGVFALALRVELLTPGETVMGRLAYNRAFTVH
GVVMVWLFLIPSIPTAFGNFLLPLMIGARDVAFPRLNLASFYLYVLGAVMTLWGVFQGGVDTGWTFYTPYSTATGREVMP
VLLGVFVVGFSTIITGINFITTVHTLRAPGVTWMKVPLFVWAIYGTSIIQVLATPVLGMVLVLVALERVAGAGLFDPSRG
GDPLLFQHLFWFYSHPAVYIMVLPGMGVISETVCAFSRKRPFSYRVIVWSTVGISFVGFLTWGHHMFVSGQSTFGAGAFS
VLSMLVAIFTAMKIFTWLGTMYRGSLWVSTPFTYVLGFIFLLFFGGMSGVAVAVTSADLHWHDTYFVVAHFHFIMVGASL
MAFLAALHYWFPKMCGRMYPEGMGIGTAVLIIFGFIATFLPQFLLGNLGMPRRYADYPEEFQPLHVASTAGASLLGFGFL
IVAIYLGWSLRHGRAAGRNPWGSEGYEWLSDSPPPEFNFHAPPWFPRPPHDYANPGANTEVEHAA

Sequences:

>Translated_545_residues
MAPSHAESPVAAPSYLDAERGLWSWLTTRDHKRIGVMFLGVLLLMFLLGGVFALALRVELLTPGETVMGRLAYNRAFTVH
GVVMVWLFLIPSIPTAFGNFLLPLMIGARDVAFPRLNLASFYLYVLGAVMTLWGVFQGGVDTGWTFYTPYSTATGREVMP
VLLGVFVVGFSTIITGINFITTVHTLRAPGVTWMKVPLFVWAIYGTSIIQVLATPVLGMVLVLVALERVAGAGLFDPSRG
GDPLLFQHLFWFYSHPAVYIMVLPGMGVISETVCAFSRKRPFSYRVIVWSTVGISFVGFLTWGHHMFVSGQSTFGAGAFS
VLSMLVAIFTAMKIFTWLGTMYRGSLWVSTPFTYVLGFIFLLFFGGMSGVAVAVTSADLHWHDTYFVVAHFHFIMVGASL
MAFLAALHYWFPKMCGRMYPEGMGIGTAVLIIFGFIATFLPQFLLGNLGMPRRYADYPEEFQPLHVASTAGASLLGFGFL
IVAIYLGWSLRHGRAAGRNPWGSEGYEWLSDSPPPEFNFHAPPWFPRPPHDYANPGANTEVEHAA
>Mature_544_residues
APSHAESPVAAPSYLDAERGLWSWLTTRDHKRIGVMFLGVLLLMFLLGGVFALALRVELLTPGETVMGRLAYNRAFTVHG
VVMVWLFLIPSIPTAFGNFLLPLMIGARDVAFPRLNLASFYLYVLGAVMTLWGVFQGGVDTGWTFYTPYSTATGREVMPV
LLGVFVVGFSTIITGINFITTVHTLRAPGVTWMKVPLFVWAIYGTSIIQVLATPVLGMVLVLVALERVAGAGLFDPSRGG
DPLLFQHLFWFYSHPAVYIMVLPGMGVISETVCAFSRKRPFSYRVIVWSTVGISFVGFLTWGHHMFVSGQSTFGAGAFSV
LSMLVAIFTAMKIFTWLGTMYRGSLWVSTPFTYVLGFIFLLFFGGMSGVAVAVTSADLHWHDTYFVVAHFHFIMVGASLM
AFLAALHYWFPKMCGRMYPEGMGIGTAVLIIFGFIATFLPQFLLGNLGMPRRYADYPEEFQPLHVASTAGASLLGFGFLI
VAIYLGWSLRHGRAAGRNPWGSEGYEWLSDSPPPEFNFHAPPWFPRPPHDYANPGANTEVEHAA

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=505, Percent_Identity=36.8316831683168, Blast_Score=318, Evalue=9e-87,
Organism=Escherichia coli, GI1786634, Length=522, Percent_Identity=35.823754789272, Blast_Score=311, Evalue=7e-86,
Organism=Saccharomyces cerevisiae, GI6226519, Length=526, Percent_Identity=34.0304182509506, Blast_Score=303, Evalue=3e-83,
Organism=Saccharomyces cerevisiae, GI6226524, Length=320, Percent_Identity=36.5625, Blast_Score=208, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6226523, Length=244, Percent_Identity=34.4262295081967, Blast_Score=131, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 60093; Mature: 59962

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCC
>Mature Secondary Structure 
APSHAESPVAAPSYLDAERGLWSWLTTRDHKRIGVMFLGVLLLMFLLGGVFALALRVEL
CCCCCCCCCCCCCHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH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CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8387368; 8905231 [H]