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The map label for this gene is coxB [H]

Identifier: 108761189

GI number: 108761189

Start: 4646690

End: 4647730

Strand: Reverse

Name: coxB [H]

Synonym: MXAN_3869

Alternate gene names: 108761189

Gene position: 4647730-4646690 (Counterclockwise)

Preceding gene: 108762571

Following gene: 108763348

Centisome position: 50.85

GC content: 69.45

Gene sequence:

>1041_bases
ATGAGTGACCTGCTGCGGCGCATGTTGTTCCTCCCGGAGGCGGCCTCGTCGCTGGCCACACGCGTGGACCAGCTGCATTT
CTTCATCATCTGCACCACCTTCGTGGTGGGCGCCGGCATTGGCCTCACCGGACTCTTCTTCCTGGTGCGCTACCGGCGTG
GACGTGCGCCCTCGGAGGCGCCGGCGATGGCCGCGCCCACCTGGATGGAGGCCGCGTTCGCCGGCGTGCCGCTGTCCTTC
TTCCTGCTCTGGGGCGCGCTGGGCTTCCGGGACTACGTGTGGGCCCGCACGCCGCCTCGGGACGCCCTGGACGTCTACGT
CACTGGCAAGCAGTGGATGTGGAAGTTCGCCTACCCGGACGGGCCGGGGATGGTGGGCGTGCTGCACGTTCCCACCGGCA
CGCCCGTGCGCCTGCTGCTCACGTCGCGCGACGTCATCCACTCCTTCTTCGTCCCCGCCTTCCGCTTGAAGATGGATGCG
TTGCCCGGGCGCTACACGGAGATCTGGTTGGAGGTCCTGAGGCCGGGCCGCTACCAGGTGCTGTGCGCGGAGTACTGCGG
CCTGGACCATTCGCACATGCGCGCCGAGGTGGTGGCACTGGAGCCCGCGGCCTTCGAGGCATGGAGAGCCCGGCAGCGGG
CCCAGCCGACGTGGGTGGCGGACACGGCAGCCGAGGAGGCGGGCACCCAGGGACCGTTTGCCCGGCGGGGGGAGGACGTC
GCCGCGCGGCAAGGGTGTCTCCAGTGCCACACCATTGACGGTACGCCGCACATCGGTCCCACCTGGTTGGGGTTGTACGG
GCGCGATGAGCCGCTGGCCTCTGGAGGCAGCGTGCGCGTCGACGTGGCGTACCTCACCGAGTCGATGATGGACCCACTGG
CGAAGGTGGTCGCGGGCTACGCGCCGGTGATGCCGTCGTTCCACGGACGCCTGAGCGCGGGCGAAGTGGGCGCGCTCGTC
GAGTTCATCAAGTCGCTTCAGCCGGAACTTCCGGAGCCACCATCCTCCCAGGAGCCCACGTATGGCCCCCTCCCACGCTG
A

Upstream 100 bases:

>100_bases
TGCGGGGGTACGGTTGGGTGGACCGGGACGCCGGGGTCATCCACATTCCGGTGGAGCAGGCCCTGGAGCAGGTCCTCTCC
ACGGAGGAGGGGGCGCGGCC

Downstream 100 bases:

>100_bases
GTCCCCCGTGGCGGCGCCCAGCTACCTGGACGCGGAGCGAGGGCTCTGGTCCTGGCTCACCACGCGCGACCACAAGCGCA
TTGGCGTGATGTTCCTGGGC

Product: cytochrome c oxidase subunit II

Products: NA

Alternate protein names: Alternative cytochrome c oxidase polypeptide II; Cytochrome BB3 subunit 2; Oxidase BB(3) subunit 2 [H]

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MSDLLRRMLFLPEAASSLATRVDQLHFFIICTTFVVGAGIGLTGLFFLVRYRRGRAPSEAPAMAAPTWMEAAFAGVPLSF
FLLWGALGFRDYVWARTPPRDALDVYVTGKQWMWKFAYPDGPGMVGVLHVPTGTPVRLLLTSRDVIHSFFVPAFRLKMDA
LPGRYTEIWLEVLRPGRYQVLCAEYCGLDHSHMRAEVVALEPAAFEAWRARQRAQPTWVADTAAEEAGTQGPFARRGEDV
AARQGCLQCHTIDGTPHIGPTWLGLYGRDEPLASGGSVRVDVAYLTESMMDPLAKVVAGYAPVMPSFHGRLSAGEVGALV
EFIKSLQPELPEPPSSQEPTYGPLPR

Sequences:

>Translated_346_residues
MSDLLRRMLFLPEAASSLATRVDQLHFFIICTTFVVGAGIGLTGLFFLVRYRRGRAPSEAPAMAAPTWMEAAFAGVPLSF
FLLWGALGFRDYVWARTPPRDALDVYVTGKQWMWKFAYPDGPGMVGVLHVPTGTPVRLLLTSRDVIHSFFVPAFRLKMDA
LPGRYTEIWLEVLRPGRYQVLCAEYCGLDHSHMRAEVVALEPAAFEAWRARQRAQPTWVADTAAEEAGTQGPFARRGEDV
AARQGCLQCHTIDGTPHIGPTWLGLYGRDEPLASGGSVRVDVAYLTESMMDPLAKVVAGYAPVMPSFHGRLSAGEVGALV
EFIKSLQPELPEPPSSQEPTYGPLPR
>Mature_345_residues
SDLLRRMLFLPEAASSLATRVDQLHFFIICTTFVVGAGIGLTGLFFLVRYRRGRAPSEAPAMAAPTWMEAAFAGVPLSFF
LLWGALGFRDYVWARTPPRDALDVYVTGKQWMWKFAYPDGPGMVGVLHVPTGTPVRLLLTSRDVIHSFFVPAFRLKMDAL
PGRYTEIWLEVLRPGRYQVLCAEYCGLDHSHMRAEVVALEPAAFEAWRARQRAQPTWVADTAAEEAGTQGPFARRGEDVA
ARQGCLQCHTIDGTPHIGPTWLGLYGRDEPLASGGSVRVDVAYLTESMMDPLAKVVAGYAPVMPSFHGRLSAGEVGALVE
FIKSLQPELPEPPSSQEPTYGPLPR

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A ce

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=147, Percent_Identity=30.6122448979592, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI1786635, Length=211, Percent_Identity=27.0142180094787, Blast_Score=75, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6226540, Length=138, Percent_Identity=28.2608695652174, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 38107; Mature: 37976

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS00078 COX2 ; PS50857 COX2_CUA ; PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLLRRMLFLPEAASSLATRVDQLHFFIICTTFVVGAGIGLTGLFFLVRYRRGRAPSEA
CHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCC
PAMAAPTWMEAAFAGVPLSFFLLWGALGFRDYVWARTPPRDALDVYVTGKQWMWKFAYPD
CCCCCCHHHHHHHHCCCHHHHHHHHHHCHHHHHCCCCCCCCCEEEEEECCCEEEEEECCC
GPGMVGVLHVPTGTPVRLLLTSRDVIHSFFVPAFRLKMDALPGRYTEIWLEVLRPGRYQV
CCCEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEE
LCAEYCGLDHSHMRAEVVALEPAAFEAWRARQRAQPTWVADTAAEEAGTQGPFARRGEDV
EEHHHCCCCHHHHEEEEEEECCHHHHHHHHHHHCCCCEEEHHHHHHCCCCCCCHHCCCHH
AARQGCLQCHTIDGTPHIGPTWLGLYGRDEPLASGGSVRVDVAYLTESMMDPLAKVVAGY
HHHCCCEEEEEECCCCCCCCCEEECCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
APVMPSFHGRLSAGEVGALVEFIKSLQPELPEPPSSQEPTYGPLPR
HCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SDLLRRMLFLPEAASSLATRVDQLHFFIICTTFVVGAGIGLTGLFFLVRYRRGRAPSEA
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCC
PAMAAPTWMEAAFAGVPLSFFLLWGALGFRDYVWARTPPRDALDVYVTGKQWMWKFAYPD
CCCCCCHHHHHHHHCCCHHHHHHHHHHCHHHHHCCCCCCCCCEEEEEECCCEEEEEECCC
GPGMVGVLHVPTGTPVRLLLTSRDVIHSFFVPAFRLKMDALPGRYTEIWLEVLRPGRYQV
CCCEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEE
LCAEYCGLDHSHMRAEVVALEPAAFEAWRARQRAQPTWVADTAAEEAGTQGPFARRGEDV
EEHHHCCCCHHHHEEEEEEECCHHHHHHHHHHHCCCCEEEHHHHHHCCCCCCCHHCCCHH
AARQGCLQCHTIDGTPHIGPTWLGLYGRDEPLASGGSVRVDVAYLTESMMDPLAKVVAGY
HHHCCCEEEEEECCCCCCCCCEEECCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
APVMPSFHGRLSAGEVGALVEFIKSLQPELPEPPSSQEPTYGPLPR
HCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1444719; 12597275 [H]