Click here to switch to the map view.

The map label for this gene is gapA [H]

Identifier: 108763343

GI number: 108763343

Start: 3287094

End: 3288104

Strand: Direct

Name: gapA [H]

Synonym: MXAN_2815

Alternate gene names: 108763343

Gene position: 3287094-3288104 (Clockwise)

Preceding gene: 108757922

Following gene: 108757102

Centisome position: 35.96

GC content: 65.18

Gene sequence:

>1011_bases
ATGGCTACCCGGATTGCCATCAATGGTTTTGGCCGCATCGGTCGCTGCATCCTCCGCGCGGTGCTCAGCCGCAAGGAAGA
CCTCGAGATTGTCGCCATCAACGACCTCGACAAGCCCGCGGCGCTGGCGCACCTGTTCAAGTACGACTCCGTGCACCGCA
CCTGGCCGGGTGAGGTGAAGGCGACGGAGAAGGGCATCGTGGTGGACGGCAAGGAGATCACCGTCACCGCGGAGAAGGAC
CCGACGGCGCTGCCCTGGAAGAGCCTGAACGTGGACGTGGTGCTGGAGTGCACCGGCCGCTTCACCGCGCGCGACGCGGC
GGAGAAGCACCTGAAGGCGGGCGCGAAGAAGGTCATCATCTCCGCCCCGGCCAAGGGCCCGGACATCACCATCGCTTACG
GCATCAACCACAACGAGTACGACCCGGCCAAGCACCACGTCATCTCGAACGCCTCGTGCACCACCAACTGCCTGGCGCCC
ATCGCCAAGGTGCTGGTGGACAACTTCGGCATCGAGAAGGGCCTGATGACCACGGTCCACAGCTACACCAACGACCAGCG
CATCCTGGACCTCACCCACGAGGACATGCGCCGCGCCCGCGCCGCCGCGCTCTCCATGATTCCCACCAGCACCGGCGCCG
CGAAGGCCATTGGTGAGGTGATTCCGCAGCTCAAGGGCAAGATGCACGGCCTGGCCGTCCGCGTGCCGACCCCGAACGTG
TCCCTGGTGGACCTGACGGTGAACACCGAGAAGAAGGTCACCGCCGAGGCCGTCATCGAGGCCTTCCGCAAGGCCGCCGA
AGGCCCGCTCAAGGGCGTGCTGGAGTTCAGCGACGCGCAGACGGTGTCGGTGGACTACAACGGCAACCCGCACTCGGCCA
TCTTCGACTCCACCAACTGCTTCGTGATGGGCGACAACCTGCTCAAGGTCATGGCCTGGTACGACAACGAGTGGGGCTTC
TCCAACCGCATGGTGGACACGGCGAAGTTCCTCGTCTCCAAGGGCGTCTAG

Upstream 100 bases:

>100_bases
CGTTGACTCGGCGGGTCGCGATGCCTACGGTCGGCCGCCCTCGATTTTGACGTGACGACCCGTGGGTGCCTGGCACCCAC
TGCTCAAGGAGACGACGAAC

Downstream 100 bases:

>100_bases
TCCCAAGGGCGTTCAGGGCACCGAGAGGGAAGGACCGAGATGATCCGTTACATCGATGATCTGCAGCTGACCGGGAAGCG
CGTCTTCATCCGCGTGGACT

Product: glyceraldehyde-3-phosphate dehydrogenase 1

Products: NA

Alternate protein names: GAPDH 1 [H]

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MATRIAINGFGRIGRCILRAVLSRKEDLEIVAINDLDKPAALAHLFKYDSVHRTWPGEVKATEKGIVVDGKEITVTAEKD
PTALPWKSLNVDVVLECTGRFTARDAAEKHLKAGAKKVIISAPAKGPDITIAYGINHNEYDPAKHHVISNASCTTNCLAP
IAKVLVDNFGIEKGLMTTVHSYTNDQRILDLTHEDMRRARAAALSMIPTSTGAAKAIGEVIPQLKGKMHGLAVRVPTPNV
SLVDLTVNTEKKVTAEAVIEAFRKAAEGPLKGVLEFSDAQTVSVDYNGNPHSAIFDSTNCFVMGDNLLKVMAWYDNEWGF
SNRMVDTAKFLVSKGV

Sequences:

>Translated_336_residues
MATRIAINGFGRIGRCILRAVLSRKEDLEIVAINDLDKPAALAHLFKYDSVHRTWPGEVKATEKGIVVDGKEITVTAEKD
PTALPWKSLNVDVVLECTGRFTARDAAEKHLKAGAKKVIISAPAKGPDITIAYGINHNEYDPAKHHVISNASCTTNCLAP
IAKVLVDNFGIEKGLMTTVHSYTNDQRILDLTHEDMRRARAAALSMIPTSTGAAKAIGEVIPQLKGKMHGLAVRVPTPNV
SLVDLTVNTEKKVTAEAVIEAFRKAAEGPLKGVLEFSDAQTVSVDYNGNPHSAIFDSTNCFVMGDNLLKVMAWYDNEWGF
SNRMVDTAKFLVSKGV
>Mature_335_residues
ATRIAINGFGRIGRCILRAVLSRKEDLEIVAINDLDKPAALAHLFKYDSVHRTWPGEVKATEKGIVVDGKEITVTAEKDP
TALPWKSLNVDVVLECTGRFTARDAAEKHLKAGAKKVIISAPAKGPDITIAYGINHNEYDPAKHHVISNASCTTNCLAPI
AKVLVDNFGIEKGLMTTVHSYTNDQRILDLTHEDMRRARAAALSMIPTSTGAAKAIGEVIPQLKGKMHGLAVRVPTPNVS
LVDLTVNTEKKVTAEAVIEAFRKAAEGPLKGVLEFSDAQTVSVDYNGNPHSAIFDSTNCFVMGDNLLKVMAWYDNEWGFS
NRMVDTAKFLVSKGV

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7657116, Length=333, Percent_Identity=45.3453453453453, Blast_Score=313, Evalue=1e-85,
Organism=Homo sapiens, GI7669492, Length=333, Percent_Identity=45.945945945946, Blast_Score=304, Evalue=8e-83,
Organism=Escherichia coli, GI1788079, Length=327, Percent_Identity=49.2354740061162, Blast_Score=329, Evalue=1e-91,
Organism=Escherichia coli, GI1789295, Length=330, Percent_Identity=45.7575757575758, Blast_Score=312, Evalue=2e-86,
Organism=Caenorhabditis elegans, GI17534679, Length=338, Percent_Identity=48.2248520710059, Blast_Score=325, Evalue=2e-89,
Organism=Caenorhabditis elegans, GI17534677, Length=338, Percent_Identity=47.9289940828402, Blast_Score=324, Evalue=3e-89,
Organism=Caenorhabditis elegans, GI32566163, Length=338, Percent_Identity=46.1538461538462, Blast_Score=298, Evalue=2e-81,
Organism=Caenorhabditis elegans, GI17568413, Length=338, Percent_Identity=46.1538461538462, Blast_Score=298, Evalue=2e-81,
Organism=Saccharomyces cerevisiae, GI6322409, Length=330, Percent_Identity=49.6969696969697, Blast_Score=333, Evalue=3e-92,
Organism=Saccharomyces cerevisiae, GI6321631, Length=325, Percent_Identity=49.5384615384615, Blast_Score=322, Evalue=4e-89,
Organism=Saccharomyces cerevisiae, GI6322468, Length=325, Percent_Identity=48.9230769230769, Blast_Score=320, Evalue=2e-88,
Organism=Drosophila melanogaster, GI17933600, Length=334, Percent_Identity=47.3053892215569, Blast_Score=308, Evalue=4e-84,
Organism=Drosophila melanogaster, GI18110149, Length=334, Percent_Identity=47.3053892215569, Blast_Score=308, Evalue=4e-84,
Organism=Drosophila melanogaster, GI85725000, Length=334, Percent_Identity=47.3053892215569, Blast_Score=307, Evalue=5e-84,
Organism=Drosophila melanogaster, GI22023983, Length=334, Percent_Identity=47.3053892215569, Blast_Score=307, Evalue=5e-84,
Organism=Drosophila melanogaster, GI19922412, Length=325, Percent_Identity=46.1538461538462, Blast_Score=291, Evalue=3e-79,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36489; Mature: 36358

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATRIAINGFGRIGRCILRAVLSRKEDLEIVAINDLDKPAALAHLFKYDSVHRTWPGEVK
CCEEEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCE
ATEKGIVVDGKEITVTAEKDPTALPWKSLNVDVVLECTGRFTARDAAEKHLKAGAKKVII
ECCCCEEEECCEEEEEECCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEE
SAPAKGPDITIAYGINHNEYDPAKHHVISNASCTTNCLAPIAKVLVDNFGIEKGLMTTVH
ECCCCCCCEEEEECCCCCCCCCHHHHEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHH
SYTNDQRILDLTHEDMRRARAAALSMIPTSTGAAKAIGEVIPQLKGKMHGLAVRVPTPNV
HCCCCCEEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCC
SLVDLTVNTEKKVTAEAVIEAFRKAAEGPLKGVLEFSDAQTVSVDYNGNPHSAIFDSTNC
EEEEEEECCCHHHHHHHHHHHHHHHHCCCHHEEEEECCCEEEEEEECCCCCCEEECCCCE
FVMGDNLLKVMAWYDNEWGFSNRMVDTAKFLVSKGV
EEECCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
ATRIAINGFGRIGRCILRAVLSRKEDLEIVAINDLDKPAALAHLFKYDSVHRTWPGEVK
CEEEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCE
ATEKGIVVDGKEITVTAEKDPTALPWKSLNVDVVLECTGRFTARDAAEKHLKAGAKKVII
ECCCCEEEECCEEEEEECCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEE
SAPAKGPDITIAYGINHNEYDPAKHHVISNASCTTNCLAPIAKVLVDNFGIEKGLMTTVH
ECCCCCCCEEEEECCCCCCCCCHHHHEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHH
SYTNDQRILDLTHEDMRRARAAALSMIPTSTGAAKAIGEVIPQLKGKMHGLAVRVPTPNV
HCCCCCEEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCC
SLVDLTVNTEKKVTAEAVIEAFRKAAEGPLKGVLEFSDAQTVSVDYNGNPHSAIFDSTNC
EEEEEEECCCHHHHHHHHHHHHHHHHCCCHHEEEEECCCEEEEEEECCCCCCEEECCCCE
FVMGDNLLKVMAWYDNEWGFSNRMVDTAKFLVSKGV
EEECCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA