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The map label for this gene is pgk [H]

Identifier: 108757102

GI number: 108757102

Start: 3288144

End: 3289331

Strand: Direct

Name: pgk [H]

Synonym: MXAN_2816

Alternate gene names: 108757102

Gene position: 3288144-3289331 (Clockwise)

Preceding gene: 108763343

Following gene: 108760209

Centisome position: 35.98

GC content: 66.84

Gene sequence:

>1188_bases
ATGATCCGTTACATCGATGATCTGCAGCTGACCGGGAAGCGCGTCTTCATCCGCGTGGACTTCAACGTCCCGATGGAAGG
ACGGCGCGTGACCGACGACACCCGCATCCGCGAGGCGATGCCCACCATCCGGCGCGCGCTCGAAATGGGCGGGAAGGTCA
TCCTGGCCTCCCACCTCGGCCGCCCCAAGGGACCGGACCCGAAGCTGTCGCTGGAGCCTGTCGCCGTGCGGCTCGCCGAG
CTGCTCGGCGGCAAGCACGAAGTCATCCTCACCGACGACTGCGTCGGTGACGGCGTGAAGAAGCAGGTGAAGGAGCTCAA
GGACGGCCAGGTGGTCGTCCTGGAGAACCTCCGCTTCCACAAGGAAGAGGAGGCCAACGACGAGACGTTCGCCCGCGAGC
TGGCGGCGCTGGCGGACGTCTATGTCAACGACGCCTTCGGCACCGCCCACCGCGCCCACGCGTCCACCGCGGGCATGGTG
CCCTTCGTGAAGGAGAAGGCGGCCGGCTTCCTGATGCGGAAGGAAATCGAGTACCTGGGCAAGGTGCTCAAGAACCCGGA
CAAGCCCTTCGTGGCCATCCTGGGTGGCTCGAAGGTGAGCGACAAAATCAAGGTCATCGAGAGCCTGCTGCCCAAGGTGG
ACGCGCTGCTCGTCGGTGGCGCCATGGCGTACACCTTCCTGAAGGCGCAGGGCGTCGAGGTGGGCAAGTCCCGCGTCGAG
GGCGACAAGCTGTCGCTGGCCACGCGTCTGCTGGAGGCTGCGCACCGGTTCAAGACGCAGCTGGTCCTGCCGGTGGACCA
CATCGTGGGCACCGAGCCCACGGAGAACAGCCCCGCCACGGAGACGCCGGACAACGCGATTCCGCCGGACATGATGGGCC
TGGACATCGGTCCCAAGACGCGCGCCATCTTCGCGCAGCACATCCGCGATGCGAGGACGGTGGTGTGGAACGGGCCCATG
GGCCTGTTCGAGGTCCCCAAGTTCGCCGAGGGCACTCGCTCCGTCGCCGCGGCCATGGCCATCAACACGCAGGCCACCAC
CGTCATCGGCGGCGGGGACAGCGCGGCGGCCGTGGAGCAGATGGGCTTCGCGGACAAGATGAGCCATGTGTCCACTGGTG
GAGGGGCGTCCTTGGAATTCCTGGAAGGACGCGACTTGCCGGGCATCAAGGCGCTGGAGACGCGGTAG

Upstream 100 bases:

>100_bases
GTGGGGCTTCTCCAACCGCATGGTGGACACGGCGAAGTTCCTCGTCTCCAAGGGCGTCTAGTCCCAAGGGCGTTCAGGGC
ACCGAGAGGGAAGGACCGAG

Downstream 100 bases:

>100_bases
GCTCCGCGTCCGACACACCACACACCCCTGGGGGACACCATGGCCACCGCGCGTCGTCGGAAGATCGTTGCTGGCAACTG
GAAGATGAACAAGTCGGTAC

Product: phosphoglycerate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MIRYIDDLQLTGKRVFIRVDFNVPMEGRRVTDDTRIREAMPTIRRALEMGGKVILASHLGRPKGPDPKLSLEPVAVRLAE
LLGGKHEVILTDDCVGDGVKKQVKELKDGQVVVLENLRFHKEEEANDETFARELAALADVYVNDAFGTAHRAHASTAGMV
PFVKEKAAGFLMRKEIEYLGKVLKNPDKPFVAILGGSKVSDKIKVIESLLPKVDALLVGGAMAYTFLKAQGVEVGKSRVE
GDKLSLATRLLEAAHRFKTQLVLPVDHIVGTEPTENSPATETPDNAIPPDMMGLDIGPKTRAIFAQHIRDARTVVWNGPM
GLFEVPKFAEGTRSVAAAMAINTQATTVIGGGDSAAAVEQMGFADKMSHVSTGGGASLEFLEGRDLPGIKALETR

Sequences:

>Translated_395_residues
MIRYIDDLQLTGKRVFIRVDFNVPMEGRRVTDDTRIREAMPTIRRALEMGGKVILASHLGRPKGPDPKLSLEPVAVRLAE
LLGGKHEVILTDDCVGDGVKKQVKELKDGQVVVLENLRFHKEEEANDETFARELAALADVYVNDAFGTAHRAHASTAGMV
PFVKEKAAGFLMRKEIEYLGKVLKNPDKPFVAILGGSKVSDKIKVIESLLPKVDALLVGGAMAYTFLKAQGVEVGKSRVE
GDKLSLATRLLEAAHRFKTQLVLPVDHIVGTEPTENSPATETPDNAIPPDMMGLDIGPKTRAIFAQHIRDARTVVWNGPM
GLFEVPKFAEGTRSVAAAMAINTQATTVIGGGDSAAAVEQMGFADKMSHVSTGGGASLEFLEGRDLPGIKALETR
>Mature_395_residues
MIRYIDDLQLTGKRVFIRVDFNVPMEGRRVTDDTRIREAMPTIRRALEMGGKVILASHLGRPKGPDPKLSLEPVAVRLAE
LLGGKHEVILTDDCVGDGVKKQVKELKDGQVVVLENLRFHKEEEANDETFARELAALADVYVNDAFGTAHRAHASTAGMV
PFVKEKAAGFLMRKEIEYLGKVLKNPDKPFVAILGGSKVSDKIKVIESLLPKVDALLVGGAMAYTFLKAQGVEVGKSRVE
GDKLSLATRLLEAAHRFKTQLVLPVDHIVGTEPTENSPATETPDNAIPPDMMGLDIGPKTRAIFAQHIRDARTVVWNGPM
GLFEVPKFAEGTRSVAAAMAINTQATTVIGGGDSAAAVEQMGFADKMSHVSTGGGASLEFLEGRDLPGIKALETR

Specific function: Second phase of glycolysis; second step. [C]

COG id: COG0126

COG function: function code G; 3-phosphoglycerate kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate kinase family [H]

Homologues:

Organism=Homo sapiens, GI31543397, Length=412, Percent_Identity=45.6310679611651, Blast_Score=345, Evalue=5e-95,
Organism=Homo sapiens, GI4505763, Length=412, Percent_Identity=45.3883495145631, Blast_Score=344, Evalue=6e-95,
Organism=Escherichia coli, GI1789294, Length=391, Percent_Identity=47.3145780051151, Blast_Score=325, Evalue=3e-90,
Organism=Caenorhabditis elegans, GI17508823, Length=409, Percent_Identity=48.1662591687042, Blast_Score=360, Evalue=1e-99,
Organism=Saccharomyces cerevisiae, GI6319857, Length=412, Percent_Identity=46.6019417475728, Blast_Score=351, Evalue=1e-97,
Organism=Drosophila melanogaster, GI17136394, Length=411, Percent_Identity=45.985401459854, Blast_Score=337, Evalue=7e-93,
Organism=Drosophila melanogaster, GI24581203, Length=410, Percent_Identity=46.0975609756098, Blast_Score=337, Evalue=7e-93,

Paralogues:

None

Copy number: 2990 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1460 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001576
- InterPro:   IPR015901
- InterPro:   IPR015911
- InterPro:   IPR015824 [H]

Pfam domain/function: PF00162 PGK [H]

EC number: =2.7.2.3 [H]

Molecular weight: Translated: 42707; Mature: 42707

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS00111 PGLYCERATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRYIDDLQLTGKRVFIRVDFNVPMEGRRVTDDTRIREAMPTIRRALEMGGKVILASHLG
CCEEECCEEECCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCC
RPKGPDPKLSLEPVAVRLAELLGGKHEVILTDDCVGDGVKKQVKELKDGQVVVLENLRFH
CCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCCCCEEEEECCCCC
KEEEANDETFARELAALADVYVNDAFGTAHRAHASTAGMVPFVKEKAAGFLMRKEIEYLG
CCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
KVLKNPDKPFVAILGGSKVSDKIKVIESLLPKVDALLVGGAMAYTFLKAQGVEVGKSRVE
HHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCC
GDKLSLATRLLEAAHRFKTQLVLPVDHIVGTEPTENSPATETPDNAIPPDMMGLDIGPKT
CHHHHHHHHHHHHHHHHHHEEEEEHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
RAIFAQHIRDARTVVWNGPMGLFEVPKFAEGTRSVAAAMAINTQATTVIGGGDSAAAVEQ
HHHHHHHHHCCCEEEECCCCCHHCCCCHHHHHHHHHHHHEECCCEEEEEECCCCHHHHHH
MGFADKMSHVSTGGGASLEFLEGRDLPGIKALETR
HCCHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MIRYIDDLQLTGKRVFIRVDFNVPMEGRRVTDDTRIREAMPTIRRALEMGGKVILASHLG
CCEEECCEEECCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCC
RPKGPDPKLSLEPVAVRLAELLGGKHEVILTDDCVGDGVKKQVKELKDGQVVVLENLRFH
CCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCCCCEEEEECCCCC
KEEEANDETFARELAALADVYVNDAFGTAHRAHASTAGMVPFVKEKAAGFLMRKEIEYLG
CCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
KVLKNPDKPFVAILGGSKVSDKIKVIESLLPKVDALLVGGAMAYTFLKAQGVEVGKSRVE
HHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCC
GDKLSLATRLLEAAHRFKTQLVLPVDHIVGTEPTENSPATETPDNAIPPDMMGLDIGPKT
CHHHHHHHHHHHHHHHHHHEEEEEHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
RAIFAQHIRDARTVVWNGPMGLFEVPKFAEGTRSVAAAMAINTQATTVIGGGDSAAAVEQ
HHHHHHHHHCCCEEEECCCCCHHCCCCHHHHHHHHHHHHEECCCEEEEEECCCCHHHHHH
MGFADKMSHVSTGGGASLEFLEGRDLPGIKALETR
HCCHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA