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The map label for this gene is hflC [H]

Identifier: 108763305

GI number: 108763305

Start: 3716559

End: 3717500

Strand: Direct

Name: hflC [H]

Synonym: MXAN_3172

Alternate gene names: 108763305

Gene position: 3716559-3717500 (Clockwise)

Preceding gene: 108758403

Following gene: 108762299

Centisome position: 40.66

GC content: 66.67

Gene sequence:

>942_bases
ATGAGCCGCCTTGTCATTCCCCTTGGCGTATTGGCCGTCCTGGCCGTGGTGCTGGGCTTCTCCGCGACCTACACCCTGAG
CGAGCACGAGCAGGCCGTCATCACGCGGTTCGGCGAGCCGAAGGGCGCGTCCGTCGTAGACCCGGGGCTCCACTTCAAGA
TGCCCTTTGTCGACACGGTGAACCGCTTCGACAAGCGGTGGCTGGACTGGCGCGGTGACCCGAACCAGATACCCACCAAG
GACAAGAAGTACATCTGGGTGGACACCTTTGGTCGCTGGCGCATCGTGGACCCGCTGCGCTTCTTTCAGCGCCTGCGGGA
CGAGCGCAACGCGCAGTCCCGGCTCGACGACATCATCGACGGTGAGACGCGCAACACCATCGCGTCGTTCGCGCTGATTG
AGGCGGTCCGCTCCACGAACCGTCCCTTCGAGGACGACGAGTACACCGCCGAGACGGAGCGGGCGGAGTCGCTGGAGCAG
GTCGCCCAGGGGCGGGACAAGCTCACTCGCCAGATTCGGCTGCGGGCCGCGGAGATCGTCAAGGAGTTCGGGGTGGAGCT
GGTCGACGTGCAGATCCGCCGCATCAACTACGTGGACGAGGTCCAGGTGAAGGTGTTCGAGCGGATGATCTCCGAGCGCA
AGCGCATCGCCGAGCGCTCCCGCTCGGAGGGCATGGGCCGCGCGGCGGAGGTCCGGGGCCAGCGTGAGCGTGACTTGAAG
GAGATCCGCTCGGCGGCCTACCGCAAGGCCCAGGACGTCACCGGCGCCGCGGACGCCGAGGCGACGAAGATCTACGCGGA
GGCCTTCGGCCGGGACCCGGAGTTCTACCAGTTCATGCGGACGCTGGAGGCCTACCCGGACGTCGTGGACAGCTCCACGT
CGCTGTTCCTGGGCGGCGAGTCCGAGTTCTACCGGTACCTGCGCAGCAGCTCCAAGAAGTAG

Upstream 100 bases:

>100_bases
TCGTCTTGGATGAGTCCGTCAAGGGGCTCACGCCGCTGTTGAACATGCAGGCGACCGACCCCGCGGTGTCCGGGAGCGCG
AGCCAGACGGAGGGCCGCCG

Downstream 100 bases:

>100_bases
GCGGGAAGGGCGGGGCGTCAACGGCATCCTGGCCGCTGATGCCCCGCTGCCGTGCCGTACTTGCGGTGATTCGTGCCGCC
GCGAGCGAGGTGGAGGACTG

Product: HflC protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MSRLVIPLGVLAVLAVVLGFSATYTLSEHEQAVITRFGEPKGASVVDPGLHFKMPFVDTVNRFDKRWLDWRGDPNQIPTK
DKKYIWVDTFGRWRIVDPLRFFQRLRDERNAQSRLDDIIDGETRNTIASFALIEAVRSTNRPFEDDEYTAETERAESLEQ
VAQGRDKLTRQIRLRAAEIVKEFGVELVDVQIRRINYVDEVQVKVFERMISERKRIAERSRSEGMGRAAEVRGQRERDLK
EIRSAAYRKAQDVTGAADAEATKIYAEAFGRDPEFYQFMRTLEAYPDVVDSSTSLFLGGESEFYRYLRSSSKK

Sequences:

>Translated_313_residues
MSRLVIPLGVLAVLAVVLGFSATYTLSEHEQAVITRFGEPKGASVVDPGLHFKMPFVDTVNRFDKRWLDWRGDPNQIPTK
DKKYIWVDTFGRWRIVDPLRFFQRLRDERNAQSRLDDIIDGETRNTIASFALIEAVRSTNRPFEDDEYTAETERAESLEQ
VAQGRDKLTRQIRLRAAEIVKEFGVELVDVQIRRINYVDEVQVKVFERMISERKRIAERSRSEGMGRAAEVRGQRERDLK
EIRSAAYRKAQDVTGAADAEATKIYAEAFGRDPEFYQFMRTLEAYPDVVDSSTSLFLGGESEFYRYLRSSSKK
>Mature_312_residues
SRLVIPLGVLAVLAVVLGFSATYTLSEHEQAVITRFGEPKGASVVDPGLHFKMPFVDTVNRFDKRWLDWRGDPNQIPTKD
KKYIWVDTFGRWRIVDPLRFFQRLRDERNAQSRLDDIIDGETRNTIASFALIEAVRSTNRPFEDDEYTAETERAESLEQV
AQGRDKLTRQIRLRAAEIVKEFGVELVDVQIRRINYVDEVQVKVFERMISERKRIAERSRSEGMGRAAEVRGQRERDLKE
IRSAAYRKAQDVTGAADAEATKIYAEAFGRDPEFYQFMRTLEAYPDVVDSSTSLFLGGESEFYRYLRSSSKK

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=322, Percent_Identity=27.9503105590062, Blast_Score=130, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.-

Molecular weight: Translated: 36152; Mature: 36021

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLVIPLGVLAVLAVVLGFSATYTLSEHEQAVITRFGEPKGASVVDPGLHFKMPFVDTV
CCCEEHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHCCCCCCCCEECCCCCEECCHHHHH
NRFDKRWLDWRGDPNQIPTKDKKYIWVDTFGRWRIVDPLRFFQRLRDERNAQSRLDDIID
HHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCEEEECHHHHHHHHHHHHHHHHHHHHHHC
GETRNTIASFALIEAVRSTNRPFEDDEYTAETERAESLEQVAQGRDKLTRQIRLRAAEIV
CCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEFGVELVDVQIRRINYVDEVQVKVFERMISERKRIAERSRSEGMGRAAEVRGQRERDLK
HHHCCCEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHH
EIRSAAYRKAQDVTGAADAEATKIYAEAFGRDPEFYQFMRTLEAYPDVVDSSTSLFLGGE
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHCCCCEEEECCH
SEFYRYLRSSSKK
HHHHHHHHHCCCC
>Mature Secondary Structure 
SRLVIPLGVLAVLAVVLGFSATYTLSEHEQAVITRFGEPKGASVVDPGLHFKMPFVDTV
CCEEHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHCCCCCCCCEECCCCCEECCHHHHH
NRFDKRWLDWRGDPNQIPTKDKKYIWVDTFGRWRIVDPLRFFQRLRDERNAQSRLDDIID
HHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCEEEECHHHHHHHHHHHHHHHHHHHHHHC
GETRNTIASFALIEAVRSTNRPFEDDEYTAETERAESLEQVAQGRDKLTRQIRLRAAEIV
CCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEFGVELVDVQIRRINYVDEVQVKVFERMISERKRIAERSRSEGMGRAAEVRGQRERDLK
HHHCCCEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHH
EIRSAAYRKAQDVTGAADAEATKIYAEAFGRDPEFYQFMRTLEAYPDVVDSSTSLFLGGE
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHCCCCEEEECCH
SEFYRYLRSSSKK
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9403685 [H]