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The map label for this gene is hflK [H]

Identifier: 108758403

GI number: 108758403

Start: 3715492

End: 3716562

Strand: Direct

Name: hflK [H]

Synonym: MXAN_3171

Alternate gene names: 108758403

Gene position: 3715492-3716562 (Clockwise)

Preceding gene: 108760105

Following gene: 108763305

Centisome position: 40.65

GC content: 66.67

Gene sequence:

>1071_bases
ATGTCATGGAATCCTCGCGTCATGAATTCCGACCCACGAGGGCGGGACCCGTCAGACGTCCTACGTGAGCTTCGGCGGCA
ACTGGGGCCTGGAATCGGGCGCCGCATCCTGTTCGCGGTGCTCGGCCTGTTCCTGCTGGTGGGGCTGATGACCAGCTACG
CCCAGGTGGAGCCGGACGAAGTGGGCGTCATCCTCCGGCTGGGGCGCTTCGTGGGAACGGTGGAGCCGGGCCCGCATTTC
CGGATGCCCTTCTGGGTGGACCGCATCGTGAAGGTCCCGGTGCAGCGTCAGCTCAAGGCGGAGTTCGGATTCCGCACGGA
GGCCTCCCGCTCGCGCATGGGCTCTGCCTATGCGGCGGAGTCATCGGACACGAAGCGCGAGTCGCTCATGCTCACCGGTG
ACCTCAACGTCGCGGTGGTGGAGTGGATCGTCCAGTACAAGATCAAGGACCCGTACAAGTATCTCTTCAAGGTGAAGAAC
GTGGAGAGCATGCTTCGGGACATCTCCGAGGCCTCGATGCGGGCCGTCGTGGGAGACCACTCGGTGAATGAGGTCCTCAC
CACGGGCCGCCAGGCGGTGGCCACCCAGGCCAAGCTGCTGCTCCAGGACCTGGCGGACCGCTACGAGACGGGCGTGGACA
TCCAGCAGGTGGTCCTCCAGGACGTGAACCCGCCCGACCCGGTGAAGCCGTCCTTCAACGAGGTGAACCAGGCCATCCAG
GAGAAGGAGCGCGTCATCAACGAGGCCTATGCCGAGCTGAACCGCGTCATCCCCCGCGCGAAGGGCGAGGCCGAGGAGGC
GCTGCGCAGCGCCGAGGGCTATGCCATTGAGCGTGTGAACCGCGCCAAGGGGGAGGCGGACCGCTTCGCTCGCGTCTACG
AGGAGTACCGCAAGGCGCCGGACGTCACCCGCCGCCGCATGTACCTGGAGACCGTGAGCCAGGTGCTCCGGAGCGCCGGG
CAGAAGGTCGTCTTGGATGAGTCCGTCAAGGGGCTCACGCCGCTGTTGAACATGCAGGCGACCGACCCCGCGGTGTCCGG
GAGCGCGAGCCAGACGGAGGGCCGCCGATGA

Upstream 100 bases:

>100_bases
CATACCGGTCAAGCGCGTGAGCGCTGCGCATGGTGCCCGGCTGGCTGGAATTCTCGTGGCGCCCCTTGCATGAGCAGCCT
GTACGGGGGAAGACGGATGG

Downstream 100 bases:

>100_bases
GCCGCCTTGTCATTCCCCTTGGCGTATTGGCCGTCCTGGCCGTGGTGCTGGGCTTCTCCGCGACCTACACCCTGAGCGAG
CACGAGCAGGCCGTCATCAC

Product: HflK protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MSWNPRVMNSDPRGRDPSDVLRELRRQLGPGIGRRILFAVLGLFLLVGLMTSYAQVEPDEVGVILRLGRFVGTVEPGPHF
RMPFWVDRIVKVPVQRQLKAEFGFRTEASRSRMGSAYAAESSDTKRESLMLTGDLNVAVVEWIVQYKIKDPYKYLFKVKN
VESMLRDISEASMRAVVGDHSVNEVLTTGRQAVATQAKLLLQDLADRYETGVDIQQVVLQDVNPPDPVKPSFNEVNQAIQ
EKERVINEAYAELNRVIPRAKGEAEEALRSAEGYAIERVNRAKGEADRFARVYEEYRKAPDVTRRRMYLETVSQVLRSAG
QKVVLDESVKGLTPLLNMQATDPAVSGSASQTEGRR

Sequences:

>Translated_356_residues
MSWNPRVMNSDPRGRDPSDVLRELRRQLGPGIGRRILFAVLGLFLLVGLMTSYAQVEPDEVGVILRLGRFVGTVEPGPHF
RMPFWVDRIVKVPVQRQLKAEFGFRTEASRSRMGSAYAAESSDTKRESLMLTGDLNVAVVEWIVQYKIKDPYKYLFKVKN
VESMLRDISEASMRAVVGDHSVNEVLTTGRQAVATQAKLLLQDLADRYETGVDIQQVVLQDVNPPDPVKPSFNEVNQAIQ
EKERVINEAYAELNRVIPRAKGEAEEALRSAEGYAIERVNRAKGEADRFARVYEEYRKAPDVTRRRMYLETVSQVLRSAG
QKVVLDESVKGLTPLLNMQATDPAVSGSASQTEGRR
>Mature_355_residues
SWNPRVMNSDPRGRDPSDVLRELRRQLGPGIGRRILFAVLGLFLLVGLMTSYAQVEPDEVGVILRLGRFVGTVEPGPHFR
MPFWVDRIVKVPVQRQLKAEFGFRTEASRSRMGSAYAAESSDTKRESLMLTGDLNVAVVEWIVQYKIKDPYKYLFKVKNV
ESMLRDISEASMRAVVGDHSVNEVLTTGRQAVATQAKLLLQDLADRYETGVDIQQVVLQDVNPPDPVKPSFNEVNQAIQE
KERVINEAYAELNRVIPRAKGEAEEALRSAEGYAIERVNRAKGEADRFARVYEEYRKAPDVTRRRMYLETVSQVLRSAGQ
KVVLDESVKGLTPLLNMQATDPAVSGSASQTEGRR

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=278, Percent_Identity=31.6546762589928, Blast_Score=149, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: NA

Molecular weight: Translated: 40036; Mature: 39905

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWNPRVMNSDPRGRDPSDVLRELRRQLGPGIGRRILFAVLGLFLLVGLMTSYAQVEPDE
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
VGVILRLGRFVGTVEPGPHFRMPFWVDRIVKVPVQRQLKAEFGFRTEASRSRMGSAYAAE
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHCCCHHCCC
SSDTKRESLMLTGDLNVAVVEWIVQYKIKDPYKYLFKVKNVESMLRDISEASMRAVVGDH
CCCCHHHHEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SVNEVLTTGRQAVATQAKLLLQDLADRYETGVDIQQVVLQDVNPPDPVKPSFNEVNQAIQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHH
EKERVINEAYAELNRVIPRAKGEAEEALRSAEGYAIERVNRAKGEADRFARVYEEYRKAP
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHCCC
DVTRRRMYLETVSQVLRSAGQKVVLDESVKGLTPLLNMQATDPAVSGSASQTEGRR
HHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SWNPRVMNSDPRGRDPSDVLRELRRQLGPGIGRRILFAVLGLFLLVGLMTSYAQVEPDE
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
VGVILRLGRFVGTVEPGPHFRMPFWVDRIVKVPVQRQLKAEFGFRTEASRSRMGSAYAAE
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHCCCHHCCC
SSDTKRESLMLTGDLNVAVVEWIVQYKIKDPYKYLFKVKNVESMLRDISEASMRAVVGDH
CCCCHHHHEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SVNEVLTTGRQAVATQAKLLLQDLADRYETGVDIQQVVLQDVNPPDPVKPSFNEVNQAIQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHH
EKERVINEAYAELNRVIPRAKGEAEEALRSAEGYAIERVNRAKGEADRFARVYEEYRKAP
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHCCC
DVTRRRMYLETVSQVLRSAGQKVVLDESVKGLTPLLNMQATDPAVSGSASQTEGRR
HHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]