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The map label for this gene is frzG

Identifier: 108763031

GI number: 108763031

Start: 5085042

End: 5086046

Strand: Reverse

Name: frzG

Synonym: MXAN_4139

Alternate gene names: 108763031

Gene position: 5086046-5085042 (Counterclockwise)

Preceding gene: 108760926

Following gene: 108757834

Centisome position: 55.65

GC content: 70.95

Gene sequence:

>1005_bases
ATGGCGTTTCGGGTGCTCATGGTGGGCAAGGGGCTGCGTGCGCTCGCGGCCCGGGGCCTGTTCGATGGGGAATCCCTGGT
GCCCGTGGGGCCGGCGGAGGTGGACTTCGCCGGCGCCCTGGTGGCCGTGCAGCGGCACTTCCCGGACGTGGTGCTGGTGG
ACCTGAGCGCGCTGGACGCGCTGCCCGCCATCGAGCACGTCATGGTGGAGCGGCCCGTGCCGGTGCTGGCGTTGCACCCC
GGCGTGTTGTCCGGCCAGGAGGCCTTCCAGGCGATGGTGGCGGGCGCGCTGGACGTGCTGGAGCGTCCGGCGAACCCCGG
GCCCGAGTTCTGGACGCACGTGTCGCGCAAGCTGGTGCTGCTGGCGCAGGTGAAGGCGGTGCGGCAGGTGCAGACGCGGC
CGCCACCGCAAGCGGCGCGTGAGGCGAAGCCGCCTCCTCCGTATCCGCTGGTGGCCATCGCCGCGTCCCTGGGTGGCCCC
AAGGCGGTGGCGCAGGTGCTGCGGATGATTCCGCGCGCCTTCCCGGCGCCCATCGCCTACTGCCAGCACATCAGCGACGG
TTTCACGGAAGGGCTGGCGCACTGGTTGTCCAATGAAACGGCGCTGCGCGTGCTGGAGGCCGAGCATGACGTGCTCATGG
CGCCGGGCACGGTGTACATCGCTCCGTCGGGCAGTCACCTCTTGGTCCGACCCGAGGGCAGGTTGGAGCTGGACGCGGGC
CCCGCGCTTCGCGGTTTCCGGCCGTCCTGTGACATGCTGCTGACTTCAGCGGGTGAGTCGTTCGGCCCGCGCTGCATCGG
GGTCATCCTGACGGGCATGGGGCGCGACGGGGCGCGAGGGTTGAAGGAGATTCGAGAGCGCGGCGGTCGGACCATTGCCC
AGGACGAAGCGTCGAGCGTCGTCTGGGGCATGCCGCGCGAGGCGGTGTTGATGGGCGCGGCGCACGAGGTGCTGCCACTG
AGCCGGATTGGCGCGGCGCTGATGCAGTGGGTGGATGTGTGTTGA

Upstream 100 bases:

>100_bases
TACCTCGTCAAGGGCGAGCTGGGCGTGGAGGTTCTCGCGCAGGCCATCGACCGGCTGACCTGAGGAGCCAGGCTTGGGCG
GTGGCGCGGTAGTCGCAGGA

Downstream 100 bases:

>100_bases
CGGCGAGCCAGAAAGTCTTGCAACAACTCGCGGCGCTGCTGCTGGAGCGCGCGGGGCTGAAAATCACGCCGGATGGCTTC
CACAGCCTCCGACTGGCGCT

Product: protein-glutatmate methylesterase FrzG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MAFRVLMVGKGLRALAARGLFDGESLVPVGPAEVDFAGALVAVQRHFPDVVLVDLSALDALPAIEHVMVERPVPVLALHP
GVLSGQEAFQAMVAGALDVLERPANPGPEFWTHVSRKLVLLAQVKAVRQVQTRPPPQAAREAKPPPPYPLVAIAASLGGP
KAVAQVLRMIPRAFPAPIAYCQHISDGFTEGLAHWLSNETALRVLEAEHDVLMAPGTVYIAPSGSHLLVRPEGRLELDAG
PALRGFRPSCDMLLTSAGESFGPRCIGVILTGMGRDGARGLKEIRERGGRTIAQDEASSVVWGMPREAVLMGAAHEVLPL
SRIGAALMQWVDVC

Sequences:

>Translated_334_residues
MAFRVLMVGKGLRALAARGLFDGESLVPVGPAEVDFAGALVAVQRHFPDVVLVDLSALDALPAIEHVMVERPVPVLALHP
GVLSGQEAFQAMVAGALDVLERPANPGPEFWTHVSRKLVLLAQVKAVRQVQTRPPPQAAREAKPPPPYPLVAIAASLGGP
KAVAQVLRMIPRAFPAPIAYCQHISDGFTEGLAHWLSNETALRVLEAEHDVLMAPGTVYIAPSGSHLLVRPEGRLELDAG
PALRGFRPSCDMLLTSAGESFGPRCIGVILTGMGRDGARGLKEIRERGGRTIAQDEASSVVWGMPREAVLMGAAHEVLPL
SRIGAALMQWVDVC
>Mature_333_residues
AFRVLMVGKGLRALAARGLFDGESLVPVGPAEVDFAGALVAVQRHFPDVVLVDLSALDALPAIEHVMVERPVPVLALHPG
VLSGQEAFQAMVAGALDVLERPANPGPEFWTHVSRKLVLLAQVKAVRQVQTRPPPQAAREAKPPPPYPLVAIAASLGGPK
AVAQVLRMIPRAFPAPIAYCQHISDGFTEGLAHWLSNETALRVLEAEHDVLMAPGTVYIAPSGSHLLVRPEGRLELDAGP
ALRGFRPSCDMLLTSAGESFGPRCIGVILTGMGRDGARGLKEIRERGGRTIAQDEASSVVWGMPREAVLMGAAHEVLPLS
RIGAALMQWVDVC

Specific function: Probable methylesterase. Required for the normal aggregation of M.xanthus cells during fruiting body formation. It is also a component of a sensory transduction pathway that controls the frequency at which cells reverse their gliding direction. It may rem

COG id: COG2201

COG function: function code NT; Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cheB-type methylesterase domain

Homologues:

Organism=Escherichia coli, GI1788192, Length=298, Percent_Identity=33.8926174496644, Blast_Score=147, Evalue=7e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FRZG_MYXXA (P31758)

Other databases:

- EMBL:   M35200
- PIR:   A36707
- ProteinModelPortal:   P31758
- BRENDA:   3.1.1.61
- GO:   GO:0005737
- GO:   GO:0006935
- InterPro:   IPR008248
- InterPro:   IPR000673
- Gene3D:   G3DSA:3.40.50.180
- PIRSF:   PIRSF000876

Pfam domain/function: PF01339 CheB_methylest; SSF52738 Chemotax_RR_pGlu_Me-esterase

EC number: =3.1.1.61

Molecular weight: Translated: 35498; Mature: 35367

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: PS50122 CHEB

Important sites: ACT_SITE 156-156 ACT_SITE 183-183 ACT_SITE 276-276

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFRVLMVGKGLRALAARGLFDGESLVPVGPAEVDFAGALVAVQRHFPDVVLVDLSALDA
CEEEEEEECCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEHHHHHH
LPAIEHVMVERPVPVLALHPGVLSGQEAFQAMVAGALDVLERPANPGPEFWTHVSRKLVL
HHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
LAQVKAVRQVQTRPPPQAAREAKPPPPYPLVAIAASLGGPKAVAQVLRMIPRAFPAPIAY
HHHHHHHHHHHCCCCCHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHH
CQHISDGFTEGLAHWLSNETALRVLEAEHDVLMAPGTVYIAPSGSHLLVRPEGRLELDAG
HHHHHHHHHHHHHHHHCCHHHEEEEECCCCEEECCCEEEEECCCCEEEECCCCCEEECCC
PALRGFRPSCDMLLTSAGESFGPRCIGVILTGMGRDGARGLKEIRERGGRTIAQDEASSV
CCCCCCCCCHHHHHHHCCCCCCCCEEEHHEECCCCCHHHHHHHHHHHCCCEEEHHCCCCE
VWGMPREAVLMGAAHEVLPLSRIGAALMQWVDVC
ECCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AFRVLMVGKGLRALAARGLFDGESLVPVGPAEVDFAGALVAVQRHFPDVVLVDLSALDA
EEEEEEECCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEHHHHHH
LPAIEHVMVERPVPVLALHPGVLSGQEAFQAMVAGALDVLERPANPGPEFWTHVSRKLVL
HHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
LAQVKAVRQVQTRPPPQAAREAKPPPPYPLVAIAASLGGPKAVAQVLRMIPRAFPAPIAY
HHHHHHHHHHHCCCCCHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHH
CQHISDGFTEGLAHWLSNETALRVLEAEHDVLMAPGTVYIAPSGSHLLVRPEGRLELDAG
HHHHHHHHHHHHHHHHCCHHHEEEEECCCCEEECCCEEEEECCCCEEEECCCCCEEECCC
PALRGFRPSCDMLLTSAGESFGPRCIGVILTGMGRDGARGLKEIRERGGRTIAQDEASSV
CCCCCCCCCHHHHHHHCCCCCCCCEEEHHEECCCCCHHHHHHHHHHHCCCEEEHHCCCCE
VWGMPREAVLMGAAHEVLPLSRIGAALMQWVDVC
ECCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2168368