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The map label for this gene is frzF

Identifier: 108757834

GI number: 108757834

Start: 5083267

End: 5085048

Strand: Reverse

Name: frzF

Synonym: MXAN_4138

Alternate gene names: 108757834

Gene position: 5085048-5083267 (Counterclockwise)

Preceding gene: 108763031

Following gene: 108762906

Centisome position: 55.64

GC content: 70.88

Gene sequence:

>1782_bases
GTGTTGACGGCGAGCCAGAAAGTCTTGCAACAACTCGCGGCGCTGCTGCTGGAGCGCGCGGGGCTGAAAATCACGCCGGA
TGGCTTCCACAGCCTCCGACTGGCGCTGTCCGCGCGGATGCCCGTGCTGGGGCTGGAAGAGCCCGAGCACTACATCCAGC
GACTGACGGGCGCCGGTGGCGAAGAGGAGCTGCGCTCGCTGTTGCCGCTGGTGACGGTGGGGCACACGGAGTTCTTCCGC
GACGCGAAGCAGTTCCGCGCGCTGGAGAAGAGCGTGCTGCCGGACCTGGTGTCCCGTTCGCGGCGCGAGATGCGCAAGGT
GTCCATCTGGTCCGCGGGCTGCGCGACGGGGGAGGAGCCCTACAGCCTGGCCATGGTGCTGGCGGAGCTGGGCGCGCTGT
CGCTGGAGGTGGACCTGTGGGCCACCGACCTCAACCTGGCCGCGGTGGAGGCCGCGAAGCAGGGGCGCTTCACCTCGCGG
CGGGCCATCAGCATCAACCAGGCGCGGCTGACGCGCTTCTTCAAGCCCGTGGAAGAGGGCTATGAGGCGCTGCCCGCGCT
GCGTGAGTACATCCGCTTCGATGGACAGAACCTGGCGGTTCCCGTCTTCGACAAGGTGGCCCTGTCGTCGCTGGACCTCA
TCCTCTGCCGCAACGTCATCATCTACTTCGACCTGCCCACCATCCGCGGGTTGATGGACCGCTTCCTCGCCGCGCTGCGG
CCGGGCGGGCTGTTGTTCCTGGGGTACTCGGAGAGCCTCTTCAAGGTCTACGACCGCTTCGAGATGATCGAAGTCGATGG
GGCGTTCGTGTACCGCCGCCCGCTGAACGACAAGAGCATGCGGGCGCCGCCGCTGCGCATCACCCCGTATCCTGGCGAGC
CCGATGTCGCCGCGCGCAGGCCCGTGCCTGCGGACGCGTTCACCGCGGACCTGCGCAAGCGGATGCTGCCCGAGGACGTC
CCGTTGACGACGCGGCTGCCCGCGGTGTCAGCGTCGTCGGTGGCGGCGCCTGGCTCGCCCAGCGTGACGCTGCCGGCGCT
GGGGGCCTCTTCGAGTCCGCGTTCCGTGGTGCCGGGGCGGCTGCCCGCGGTGTCGCCTCACTCGCCGCTGCCGGCCATCG
CCGCGCGCTCGCGTGTCACCGCGGAGTTGCCCACGGTGGGAAGCGTGGACTCCGCCCGTCCGCGCATCACCACCGAGCTG
CCGGCCGTGGCCACCACGCCGCGCGCGCCCACCGTGGAGGTGCCCGCCTGGCCCACGCTGCTGCCTCCGGCGGAGCGGCT
GGCCATGGCGGTGCGGAAGATGGCGCAGGGGGATTTCTCGGCGGCCATCGCTGGCGTGCAGCGGCTGCTCGCGGACGAGC
CCAGTGACTTGGATGGGCTGCTGACGCTGGGCAACCTGTTCTCGCTCACCGGCCGCATCCCCGAGGCGCGCGAGGCCTTC
GCGCAGGCCATTCAGCGCGAGCCGCTGTGCGTGGAGGCGCGGGTGTTCGGCGGGGTCGCCGCGTTGCAAGCAGGGGAGTT
GAGCGAGGCGCGCTCCGAGCTGAGCAAGGCCCTGTTCCTGGAGCCCACGCTGGCCATTGGCCACTACCTGCTGGCGCAGG
TGCACGAGCGCACGCAGGACCATGAGGCGGCCCGCCGCAGCTACCGCAACGCCATTGCCCAGCTTCGCTTCCCGCAGCGT
CCCCTCGCGGGGCACTACCCGGAGATGCCGGACTCGGCGGATGCCATCTCTCGCGCGGCGCGTTACGCCCTGGCCGCGCT
GGAGGAGCAGCCCCTGCGCTGA

Upstream 100 bases:

>100_bases
TCGTCTGGGGCATGCCGCGCGAGGCGGTGTTGATGGGCGCGGCGCACGAGGTGCTGCCACTGAGCCGGATTGGCGCGGCG
CTGATGCAGTGGGTGGATGT

Downstream 100 bases:

>100_bases
GGCAGGGGCCGCGTCCCAGGCTTCACGTCAGTCCAGGCTGCTCTTCACCTGGTCCAGGCTCTTGCTCGGGTCGAGCACGG
AGCCGAACTTCTTCTGCAGG

Product: protein methyltransferase FrzF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 593; Mature: 593

Protein sequence:

>593_residues
MLTASQKVLQQLAALLLERAGLKITPDGFHSLRLALSARMPVLGLEEPEHYIQRLTGAGGEEELRSLLPLVTVGHTEFFR
DAKQFRALEKSVLPDLVSRSRREMRKVSIWSAGCATGEEPYSLAMVLAELGALSLEVDLWATDLNLAAVEAAKQGRFTSR
RAISINQARLTRFFKPVEEGYEALPALREYIRFDGQNLAVPVFDKVALSSLDLILCRNVIIYFDLPTIRGLMDRFLAALR
PGGLLFLGYSESLFKVYDRFEMIEVDGAFVYRRPLNDKSMRAPPLRITPYPGEPDVAARRPVPADAFTADLRKRMLPEDV
PLTTRLPAVSASSVAAPGSPSVTLPALGASSSPRSVVPGRLPAVSPHSPLPAIAARSRVTAELPTVGSVDSARPRITTEL
PAVATTPRAPTVEVPAWPTLLPPAERLAMAVRKMAQGDFSAAIAGVQRLLADEPSDLDGLLTLGNLFSLTGRIPEAREAF
AQAIQREPLCVEARVFGGVAALQAGELSEARSELSKALFLEPTLAIGHYLLAQVHERTQDHEAARRSYRNAIAQLRFPQR
PLAGHYPEMPDSADAISRAARYALAALEEQPLR

Sequences:

>Translated_593_residues
MLTASQKVLQQLAALLLERAGLKITPDGFHSLRLALSARMPVLGLEEPEHYIQRLTGAGGEEELRSLLPLVTVGHTEFFR
DAKQFRALEKSVLPDLVSRSRREMRKVSIWSAGCATGEEPYSLAMVLAELGALSLEVDLWATDLNLAAVEAAKQGRFTSR
RAISINQARLTRFFKPVEEGYEALPALREYIRFDGQNLAVPVFDKVALSSLDLILCRNVIIYFDLPTIRGLMDRFLAALR
PGGLLFLGYSESLFKVYDRFEMIEVDGAFVYRRPLNDKSMRAPPLRITPYPGEPDVAARRPVPADAFTADLRKRMLPEDV
PLTTRLPAVSASSVAAPGSPSVTLPALGASSSPRSVVPGRLPAVSPHSPLPAIAARSRVTAELPTVGSVDSARPRITTEL
PAVATTPRAPTVEVPAWPTLLPPAERLAMAVRKMAQGDFSAAIAGVQRLLADEPSDLDGLLTLGNLFSLTGRIPEAREAF
AQAIQREPLCVEARVFGGVAALQAGELSEARSELSKALFLEPTLAIGHYLLAQVHERTQDHEAARRSYRNAIAQLRFPQR
PLAGHYPEMPDSADAISRAARYALAALEEQPLR
>Mature_593_residues
MLTASQKVLQQLAALLLERAGLKITPDGFHSLRLALSARMPVLGLEEPEHYIQRLTGAGGEEELRSLLPLVTVGHTEFFR
DAKQFRALEKSVLPDLVSRSRREMRKVSIWSAGCATGEEPYSLAMVLAELGALSLEVDLWATDLNLAAVEAAKQGRFTSR
RAISINQARLTRFFKPVEEGYEALPALREYIRFDGQNLAVPVFDKVALSSLDLILCRNVIIYFDLPTIRGLMDRFLAALR
PGGLLFLGYSESLFKVYDRFEMIEVDGAFVYRRPLNDKSMRAPPLRITPYPGEPDVAARRPVPADAFTADLRKRMLPEDV
PLTTRLPAVSASSVAAPGSPSVTLPALGASSSPRSVVPGRLPAVSPHSPLPAIAARSRVTAELPTVGSVDSARPRITTEL
PAVATTPRAPTVEVPAWPTLLPPAERLAMAVRKMAQGDFSAAIAGVQRLLADEPSDLDGLLTLGNLFSLTGRIPEAREAF
AQAIQREPLCVEARVFGGVAALQAGELSEARSELSKALFLEPTLAIGHYLLAQVHERTQDHEAARRSYRNAIAQLRFPQR
PLAGHYPEMPDSADAISRAARYALAALEEQPLR

Specific function: This methyltransferase is one of the proteins required for the normal aggregation of M.xanthus cells during fruiting body formation. It is also a component of a sensory transduction pathway that controls the frequency at which cells reverse their gliding

COG id: COG1352

COG function: function code NT; Methylase of chemotaxis methyl-accepting proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 TPR repeats

Homologues:

Organism=Escherichia coli, GI1788193, Length=266, Percent_Identity=30.4511278195489, Blast_Score=119, Evalue=7e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FRZF_MYXXA (P31759)

Other databases:

- EMBL:   M35200
- PIR:   B36707
- ProteinModelPortal:   P31759
- BRENDA:   2.1.1.80
- GO:   GO:0005488
- GO:   GO:0006935
- InterPro:   IPR022642
- InterPro:   IPR000780
- InterPro:   IPR022641
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734
- Gene3D:   G3DSA:1.10.155.10
- Gene3D:   G3DSA:1.25.40.10
- PRINTS:   PR00996
- SMART:   SM00138
- SMART:   SM00028

Pfam domain/function: PF01739 CheR; PF03705 CheR_N; SSF47757 CheR_mtfrase

EC number: =2.1.1.80

Molecular weight: Translated: 64669; Mature: 64669

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: PS50123 CHER; PS50005 TPR; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTASQKVLQQLAALLLERAGLKITPDGFHSLRLALSARMPVLGLEEPEHYIQRLTGAGG
CCCCHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCC
EEELRSLLPLVTVGHTEFFRDAKQFRALEKSVLPDLVSRSRREMRKVSIWSAGCATGEEP
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCH
YSLAMVLAELGALSLEVDLWATDLNLAAVEAAKQGRFTSRRAISINQARLTRFFKPVEEG
HHHHHHHHHHCCEEEEEEEEEECCCHHHHHHHHCCCCCCCCEEECHHHHHHHHHHHHHHH
YEALPALREYIRFDGQNLAVPVFDKVALSSLDLILCRNVIIYFDLPTIRGLMDRFLAALR
HHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHC
PGGLLFLGYSESLFKVYDRFEMIEVDGAFVYRRPLNDKSMRAPPLRITPYPGEPDVAARR
CCCEEEECCCHHHHHHHHHHHEEEECCEEEEECCCCCCCCCCCCEEECCCCCCCCCCCCC
PVPADAFTADLRKRMLPEDVPLTTRLPAVSASSVAAPGSPSVTLPALGASSSPRSVVPGR
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCC
LPAVSPHSPLPAIAARSRVTAELPTVGSVDSARPRITTELPAVATTPRAPTVEVPAWPTL
CCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCCCEECCCCCEEECCCCCCC
LPPAERLAMAVRKMAQGDFSAAIAGVQRLLADEPSDLDGLLTLGNLFSLTGRIPEAREAF
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHH
AQAIQREPLCVEARVFGGVAALQAGELSEARSELSKALFLEPTLAIGHYLLAQVHERTQD
HHHHCCCCCEEEHHHHCCHHHHHHCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
HEAARRSYRNAIAQLRFPQRPLAGHYPEMPDSADAISRAARYALAALEEQPLR
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLTASQKVLQQLAALLLERAGLKITPDGFHSLRLALSARMPVLGLEEPEHYIQRLTGAGG
CCCCHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCC
EEELRSLLPLVTVGHTEFFRDAKQFRALEKSVLPDLVSRSRREMRKVSIWSAGCATGEEP
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCH
YSLAMVLAELGALSLEVDLWATDLNLAAVEAAKQGRFTSRRAISINQARLTRFFKPVEEG
HHHHHHHHHHCCEEEEEEEEEECCCHHHHHHHHCCCCCCCCEEECHHHHHHHHHHHHHHH
YEALPALREYIRFDGQNLAVPVFDKVALSSLDLILCRNVIIYFDLPTIRGLMDRFLAALR
HHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHC
PGGLLFLGYSESLFKVYDRFEMIEVDGAFVYRRPLNDKSMRAPPLRITPYPGEPDVAARR
CCCEEEECCCHHHHHHHHHHHEEEECCEEEEECCCCCCCCCCCCEEECCCCCCCCCCCCC
PVPADAFTADLRKRMLPEDVPLTTRLPAVSASSVAAPGSPSVTLPALGASSSPRSVVPGR
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCC
LPAVSPHSPLPAIAARSRVTAELPTVGSVDSARPRITTELPAVATTPRAPTVEVPAWPTL
CCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCCCEECCCCCEEECCCCCCC
LPPAERLAMAVRKMAQGDFSAAIAGVQRLLADEPSDLDGLLTLGNLFSLTGRIPEAREAF
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHH
AQAIQREPLCVEARVFGGVAALQAGELSEARSELSKALFLEPTLAIGHYLLAQVHERTQD
HHHHCCCCCEEEHHHHCCHHHHHHCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
HEAARRSYRNAIAQLRFPQRPLAGHYPEMPDSADAISRAARYALAALEEQPLR
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2168368