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The map label for this gene is cat1 [H]

Identifier: 108762991

GI number: 108762991

Start: 2652919

End: 2654448

Strand: Reverse

Name: cat1 [H]

Synonym: MXAN_2285

Alternate gene names: 108762991

Gene position: 2654448-2652919 (Counterclockwise)

Preceding gene: 108763847

Following gene: 108757720

Centisome position: 29.04

GC content: 66.27

Gene sequence:

>1530_bases
ATGACCGTGACGAGCACGCTGAAGGACCGCATCGAGAACACCGAGTTGCTGGCGAAGGTCGTCCCCGTCGAAGAGGCGGT
GAAGCACGTCGTCCACGGCAACACCGTGGCCATCAGCGGCTTCACCAAGTCGGGTGAGCCGAAGACGTTCCTGCCGGCGC
TTGCCTGGCACTTCTCCCAGACGGCACCGGACGCCCGCATCACCCTGCTGTCCGGCGCGTCCCTGTCCGAGGATGTGGAG
GGCCCCATGGCGCCCTTCATCGCCAAGCGCGGTCCGTACATGTCCTCGCCTGCCTCGCGGCGCCGCATCCATGCCGGAGA
GATGGACTTCACGGACGTCCACCTGTCCGCCTTCGCGCGCAACCTGATGTATGGCTTCTACGGCGACATCGACGTGGCCG
TCGTCGAGGTGTCGCGCATCCGGAAGAACGGCAGCGTCGTCCTCACGTCGTCGGTGGGAATCAGCGCGGAGGCGCTGGCC
CGCGCGAAGAAGATCGTCCTCGAGGTCAACACCTCCGGGCCGGACTACACGGGCTTCCACGACATCGTCCTGCCCGCCGT
CCATCCGCACGTGGGCTGGCCGCTGCCGCTGGTGAACGTGAGGGACCGCATCGGCAACCCCTACGTGGAGCTCGACCTGA
GCAAGGTGGTGGCGGTGGTGGAGTCCCGCACGCCCGACCACCCGGTGCCCTTCAAGGCGGCGGATGACACCGCCAAGCGC
ATCGCCGAGCACGTCATCGACTTCCTGATGCGCTGCCGTGAGCAGTACCAGTGGGGCAAGCGCCTGCCGCCCATCCAGTC
CGGCGTGGGCAACGTGGCCAACGCCATCATCAGCCAGCTCTACGACTCTCCCTTCCAGAAAATCCGCTTCTGGACCGAGG
TCTTCCAGGACGGGATGTTGCGCTACGTGGAGGACGACGCAAAGTTCGAATACGCGTCCGCCACCGCGGTGTCCTTCTCC
TCTGAGGGCCGCCAGCGCTTCCTCGACATGTTCGAGCGGAGCAAGGACCGGCTGGTGCTGCGGCCCATGTGGCTGTCCAA
CAGCCCCGAAATCATCTCTCGCCTCTTCGTCATCGCGATGAACACCCCCATCGAGGTGGACATCTACGGGCACGTCAACT
CCACGCACATCGACGGTTCGCGCATCGTCAACGGCCTGGGCGGCTCGGGTGACTTCTTCCGCAACGCGTACCTGAGCATC
GTCCACACGCCGTCCACGCGAAAGCTGCGGGATGGCCGCACCGTGAGCTGTGTCATGCCGTACGTGCGGCACATCGACCA
CACCGAGCACGACATCAAGTGCGTCGTCACCGAGCAGGGCTACGCGCTCAACATGGACATCCGCTCGCCCAAGCGGCGCG
CCCAGGACATCATCGACCGCTGCGCGCACCCCTACTTCCGGCCGCTGCTGCACGCGTACCTGGACATGGCGGGCCCTGGC
GACGAGCCGCGCGCCACCGACATGAAGGTGCTCCAGGGCTGGTGGGCGGACTACGACGCGGCGACGCGTGCCTTCCCCCA
GAACGGCTGA

Upstream 100 bases:

>100_bases
CAACATGCCTGCCTGCCCATCTGTTCCCGGCCAACACCATGGTCACGGGAAAGACGCGGTGTGTTACACCCATTGCCCCC
ACAGCATTCACCCTCCAGGA

Downstream 100 bases:

>100_bases
GACCCCGGCGGTGGAGCGCAACGGCCGCGAAGCCTGTCCCCCGGAGCTGGCCGCCCAACTCCGGGAGGTGGACCGCCTGC
GACGCAGCGGGCGTTACGCA

Product: acetyl-CoA hydrolase/transferase family protein

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 509; Mature: 508

Protein sequence:

>509_residues
MTVTSTLKDRIENTELLAKVVPVEEAVKHVVHGNTVAISGFTKSGEPKTFLPALAWHFSQTAPDARITLLSGASLSEDVE
GPMAPFIAKRGPYMSSPASRRRIHAGEMDFTDVHLSAFARNLMYGFYGDIDVAVVEVSRIRKNGSVVLTSSVGISAEALA
RAKKIVLEVNTSGPDYTGFHDIVLPAVHPHVGWPLPLVNVRDRIGNPYVELDLSKVVAVVESRTPDHPVPFKAADDTAKR
IAEHVIDFLMRCREQYQWGKRLPPIQSGVGNVANAIISQLYDSPFQKIRFWTEVFQDGMLRYVEDDAKFEYASATAVSFS
SEGRQRFLDMFERSKDRLVLRPMWLSNSPEIISRLFVIAMNTPIEVDIYGHVNSTHIDGSRIVNGLGGSGDFFRNAYLSI
VHTPSTRKLRDGRTVSCVMPYVRHIDHTEHDIKCVVTEQGYALNMDIRSPKRRAQDIIDRCAHPYFRPLLHAYLDMAGPG
DEPRATDMKVLQGWWADYDAATRAFPQNG

Sequences:

>Translated_509_residues
MTVTSTLKDRIENTELLAKVVPVEEAVKHVVHGNTVAISGFTKSGEPKTFLPALAWHFSQTAPDARITLLSGASLSEDVE
GPMAPFIAKRGPYMSSPASRRRIHAGEMDFTDVHLSAFARNLMYGFYGDIDVAVVEVSRIRKNGSVVLTSSVGISAEALA
RAKKIVLEVNTSGPDYTGFHDIVLPAVHPHVGWPLPLVNVRDRIGNPYVELDLSKVVAVVESRTPDHPVPFKAADDTAKR
IAEHVIDFLMRCREQYQWGKRLPPIQSGVGNVANAIISQLYDSPFQKIRFWTEVFQDGMLRYVEDDAKFEYASATAVSFS
SEGRQRFLDMFERSKDRLVLRPMWLSNSPEIISRLFVIAMNTPIEVDIYGHVNSTHIDGSRIVNGLGGSGDFFRNAYLSI
VHTPSTRKLRDGRTVSCVMPYVRHIDHTEHDIKCVVTEQGYALNMDIRSPKRRAQDIIDRCAHPYFRPLLHAYLDMAGPG
DEPRATDMKVLQGWWADYDAATRAFPQNG
>Mature_508_residues
TVTSTLKDRIENTELLAKVVPVEEAVKHVVHGNTVAISGFTKSGEPKTFLPALAWHFSQTAPDARITLLSGASLSEDVEG
PMAPFIAKRGPYMSSPASRRRIHAGEMDFTDVHLSAFARNLMYGFYGDIDVAVVEVSRIRKNGSVVLTSSVGISAEALAR
AKKIVLEVNTSGPDYTGFHDIVLPAVHPHVGWPLPLVNVRDRIGNPYVELDLSKVVAVVESRTPDHPVPFKAADDTAKRI
AEHVIDFLMRCREQYQWGKRLPPIQSGVGNVANAIISQLYDSPFQKIRFWTEVFQDGMLRYVEDDAKFEYASATAVSFSS
EGRQRFLDMFERSKDRLVLRPMWLSNSPEIISRLFVIAMNTPIEVDIYGHVNSTHIDGSRIVNGLGGSGDFFRNAYLSIV
HTPSTRKLRDGRTVSCVMPYVRHIDHTEHDIKCVVTEQGYALNMDIRSPKRRAQDIIDRCAHPYFRPLLHAYLDMAGPGD
EPRATDMKVLQGWWADYDAATRAFPQNG

Specific function: Forms succinyl-CoA from succinate and acetyl-CoA [H]

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=466, Percent_Identity=40.343347639485, Blast_Score=326, Evalue=2e-90,
Organism=Saccharomyces cerevisiae, GI6319456, Length=490, Percent_Identity=40.6122448979592, Blast_Score=347, Evalue=2e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702
- InterPro:   IPR006472
- InterPro:   IPR017821 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro; PF04223 CitF [H]

EC number: NA

Molecular weight: Translated: 56863; Mature: 56732

Theoretical pI: Translated: 7.33; Mature: 7.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVTSTLKDRIENTELLAKVVPVEEAVKHVVHGNTVAISGFTKSGEPKTFLPALAWHFSQ
CCCCHHHHHHHCCHHHHHHHCCHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHC
TAPDARITLLSGASLSEDVEGPMAPFIAKRGPYMSSPASRRRIHAGEMDFTDVHLSAFAR
CCCCCEEEEEECCCCCCCCCCCHHHHHHCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHH
NLMYGFYGDIDVAVVEVSRIRKNGSVVLTSSVGISAEALARAKKIVLEVNTSGPDYTGFH
HHHHHHCCCCHHEEEEHHHHCCCCCEEEEECCCCCHHHHHHHEEEEEEEECCCCCCCCHH
DIVLPAVHPHVGWPLPLVNVRDRIGNPYVELDLSKVVAVVESRTPDHPVPFKAADDTAKR
HHHHCCCCCCCCCCCCCCHHHHHHCCCEEEEEHHHHHHHHHCCCCCCCCCCCCCCHHHHH
IAEHVIDFLMRCREQYQWGKRLPPIQSGVGNVANAIISQLYDSPFQKIRFWTEVFQDGML
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCHH
RYVEDDAKFEYASATAVSFSSEGRQRFLDMFERSKDRLVLRPMWLSNSPEIISRLFVIAM
HHHCCCCCEEECCCEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHEEE
NTPIEVDIYGHVNSTHIDGSRIVNGLGGSGDFFRNAYLSIVHTPSTRKLRDGRTVSCVMP
CCCEEEEEEECCCCCCCCHHHHHCCCCCCCHHHHCEEEEEEECCCCCCCCCCCCHHHHHH
YVRHIDHTEHDIKCVVTEQGYALNMDIRSPKRRAQDIIDRCAHPYFRPLLHAYLDMAGPG
HHHHCCCCCCCEEEEEECCCEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCC
DEPRATDMKVLQGWWADYDAATRAFPQNG
CCCCCHHHHHHHHHCCCHHHHHCCCCCCC
>Mature Secondary Structure 
TVTSTLKDRIENTELLAKVVPVEEAVKHVVHGNTVAISGFTKSGEPKTFLPALAWHFSQ
CCCHHHHHHHCCHHHHHHHCCHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHC
TAPDARITLLSGASLSEDVEGPMAPFIAKRGPYMSSPASRRRIHAGEMDFTDVHLSAFAR
CCCCCEEEEEECCCCCCCCCCCHHHHHHCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHH
NLMYGFYGDIDVAVVEVSRIRKNGSVVLTSSVGISAEALARAKKIVLEVNTSGPDYTGFH
HHHHHHCCCCHHEEEEHHHHCCCCCEEEEECCCCCHHHHHHHEEEEEEEECCCCCCCCHH
DIVLPAVHPHVGWPLPLVNVRDRIGNPYVELDLSKVVAVVESRTPDHPVPFKAADDTAKR
HHHHCCCCCCCCCCCCCCHHHHHHCCCEEEEEHHHHHHHHHCCCCCCCCCCCCCCHHHHH
IAEHVIDFLMRCREQYQWGKRLPPIQSGVGNVANAIISQLYDSPFQKIRFWTEVFQDGML
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCHH
RYVEDDAKFEYASATAVSFSSEGRQRFLDMFERSKDRLVLRPMWLSNSPEIISRLFVIAM
HHHCCCCCEEECCCEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHEEE
NTPIEVDIYGHVNSTHIDGSRIVNGLGGSGDFFRNAYLSIVHTPSTRKLRDGRTVSCVMP
CCCEEEEEEECCCCCCCCHHHHHCCCCCCCHHHHCEEEEEEECCCCCCCCCCCCHHHHHH
YVRHIDHTEHDIKCVVTEQGYALNMDIRSPKRRAQDIIDRCAHPYFRPLLHAYLDMAGPG
HHHHCCCCCCCEEEEEECCCEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCC
DEPRATDMKVLQGWWADYDAATRAFPQNG
CCCCCHHHHHHHHHCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]