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The map label for this gene is gufA [H]

Identifier: 108762956

GI number: 108762956

Start: 5034007

End: 5034771

Strand: Reverse

Name: gufA [H]

Synonym: MXAN_4087

Alternate gene names: 108762956

Gene position: 5034771-5034007 (Counterclockwise)

Preceding gene: 108762225

Following gene: 108757667

Centisome position: 55.09

GC content: 70.72

Gene sequence:

>765_bases
ATGGGGGCGGGGTTGGTGGCAAGCCTGCTGGCGGGCACGGCGACGGGACTGGGCGCGCTGCCCGTGCTCGTCACCTCGGA
GCTCAGCCGGAAGGCCCAGGACCGGATGTTGGGCTTCAGCGCGGGCGTGATGCTGGCGGCCACGTCCTTCTCGCTGGTCA
TCCCCGCGATGGAATTGGTGAGAGGGCAGGGCCATGACGGGCCTTCGGCGGCACTGCGCGTGGCGGCGGGTGTGTTGCTG
GGTGGGCTGTTCCTGCGCGTGTGGCACGACTTGATGCCGCACGAACACGCGCTCAAGGGCCACGAGGGCCATGGCGGCAC
GAAGTGGAACAGCGCGCTGCTGTTCGTGCTGGCCATGACGCTGCACAACTTCCCGGAAGGCCTGGCGGTGGGCGTGTCCT
TCGCCGCGCCGCAGCCGGAGCTGGGCCTGTCGGTGGCGCTGGGAATCGGCGCGCAGAACATTCCCGAAGGCCTGGTGGTG
GCGCTGGCGCTGCGGGCCTCGGGGGCGTCCGCGTCGCGCGCCGCGTTCCTGGCGCTGCTCACCGGCATGGTGGAACCGGT
CGGCGCGCTGTTCGGCGTCCTGGCCCTGTCACTCAGCTCCGCGCTGCTGCCGTGGGGACTGGCCTTCGCGGGCGGGGCGA
TGCTCTATGTCATCAGCCACGAGATGATTCCGGAGAGCCACCGCGGCGGCTTCGAGCGCGAGGCCACCACCGGCCTCATG
TGGGGCTTCGTGCTCGCGTTGGTGCTGGACATGTCGCTGGGCTGA

Upstream 100 bases:

>100_bases
TGCGAACGCCAGCAGCATCCCGTCCTGCCCTGGAGGGCGAGGCCGTTAGTGTTGGGCGCGGAGGCACCTCGGACGCGTGG
ACCATTGGAGCATCGAAGGC

Downstream 100 bases:

>100_bases
CGCGGCCCGAGGGCTACGCGGGCAGCAGCACCAGTCGGGCAATCTCCGGGGGCGCGCCCACGCGCATGGGTGGGCCGACG
AAGCCACAACCCCGGCTGAC

Product: gufA protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MGAGLVASLLAGTATGLGALPVLVTSELSRKAQDRMLGFSAGVMLAATSFSLVIPAMELVRGQGHDGPSAALRVAAGVLL
GGLFLRVWHDLMPHEHALKGHEGHGGTKWNSALLFVLAMTLHNFPEGLAVGVSFAAPQPELGLSVALGIGAQNIPEGLVV
ALALRASGASASRAAFLALLTGMVEPVGALFGVLALSLSSALLPWGLAFAGGAMLYVISHEMIPESHRGGFEREATTGLM
WGFVLALVLDMSLG

Sequences:

>Translated_254_residues
MGAGLVASLLAGTATGLGALPVLVTSELSRKAQDRMLGFSAGVMLAATSFSLVIPAMELVRGQGHDGPSAALRVAAGVLL
GGLFLRVWHDLMPHEHALKGHEGHGGTKWNSALLFVLAMTLHNFPEGLAVGVSFAAPQPELGLSVALGIGAQNIPEGLVV
ALALRASGASASRAAFLALLTGMVEPVGALFGVLALSLSSALLPWGLAFAGGAMLYVISHEMIPESHRGGFEREATTGLM
WGFVLALVLDMSLG
>Mature_253_residues
GAGLVASLLAGTATGLGALPVLVTSELSRKAQDRMLGFSAGVMLAATSFSLVIPAMELVRGQGHDGPSAALRVAAGVLLG
GLFLRVWHDLMPHEHALKGHEGHGGTKWNSALLFVLAMTLHNFPEGLAVGVSFAAPQPELGLSVALGIGAQNIPEGLVVA
LALRASGASASRAAFLALLTGMVEPVGALFGVLALSLSSALLPWGLAFAGGAMLYVISHEMIPESHRGGFEREATTGLMW
GFVLALVLDMSLG

Specific function: Mediates Zinc Uptake. May Also Transport Other Divalent Cations Such As Copper And Cadmium Ions. [C]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI229577422, Length=156, Percent_Identity=45.5128205128205, Blast_Score=128, Evalue=6e-30,
Organism=Homo sapiens, GI229577418, Length=156, Percent_Identity=45.5128205128205, Blast_Score=127, Evalue=7e-30,
Organism=Escherichia coli, GI1789419, Length=201, Percent_Identity=34.3283582089552, Blast_Score=68, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17507805, Length=312, Percent_Identity=33.3333333333333, Blast_Score=140, Evalue=8e-34,
Organism=Drosophila melanogaster, GI24652846, Length=153, Percent_Identity=43.1372549019608, Blast_Score=128, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 25948; Mature: 25817

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAGLVASLLAGTATGLGALPVLVTSELSRKAQDRMLGFSAGVMLAATSFSLVIPAMELV
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGQGHDGPSAALRVAAGVLLGGLFLRVWHDLMPHEHALKGHEGHGGTKWNSALLFVLAMT
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHHHHHHHHH
LHNFPEGLAVGVSFAAPQPELGLSVALGIGAQNIPEGLVVALALRASGASASRAAFLALL
HHCCCCCCEECEECCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHH
TGMVEPVGALFGVLALSLSSALLPWGLAFAGGAMLYVISHEMIPESHRGGFEREATTGLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEHHHHHCCCHHCCCCCHHHHHHHH
WGFVLALVLDMSLG
HHHHHHHHHHHCCC
>Mature Secondary Structure 
GAGLVASLLAGTATGLGALPVLVTSELSRKAQDRMLGFSAGVMLAATSFSLVIPAMELV
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGQGHDGPSAALRVAAGVLLGGLFLRVWHDLMPHEHALKGHEGHGGTKWNSALLFVLAMT
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHHHHHHHHH
LHNFPEGLAVGVSFAAPQPELGLSVALGIGAQNIPEGLVVALALRASGASASRAAFLALL
HHCCCCCCEECEECCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHH
TGMVEPVGALFGVLALSLSSALLPWGLAFAGGAMLYVISHEMIPESHRGGFEREATTGLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEHHHHHCCCHHCCCCCHHHHHHHH
WGFVLALVLDMSLG
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934835 [H]