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The map label for this gene is fbp [H]

Identifier: 108757667

GI number: 108757667

Start: 5032150

End: 5032803

Strand: Reverse

Name: fbp [H]

Synonym: MXAN_4085

Alternate gene names: 108757667

Gene position: 5032803-5032150 (Counterclockwise)

Preceding gene: 108762956

Following gene: 108759238

Centisome position: 55.06

GC content: 68.65

Gene sequence:

>654_bases
GTGGCATCGGGAATCCTGCATAACGAATGCGTTCCCGCCGCGCTCCAGGATTCCAGGGGGGCAGGCGGGAAGGCGGCATG
GGCACACCCCTGGCCCCTTTCCCACGCCGCCGCGCCGGGGCAGGCTTCGCCATCCCGCGAGGCCGATTCCCGGTTCACGC
ACCCCTTCGAGGTCGTCATGCTCCGCTCCCTGCTGGTTCCCATGCTCCTGGCTGTCTCGCTGCTCGGCTGTGGCGACGAC
GAAAGCGTCAACCCCGATTCGGGAGACCCGACCAAGGTGACGTACGCGGAGTCACTCAATGTGGACCTGGCCGAGATGAC
CCGGCTGGAGAGCGGGCTCTACATCCAGGACACCTTCGTCGTGGAGGATGGCGCGCAGGCCGAGGCGGGCAAGCGCGTGC
AGGTGCGCTACACGGGCTACCTGCCGGACGGCCGCAGCTTCGACGCCACCGGCAACGGGCCCGCCATCGGCTTCACCCTG
GGCGTGGGGCAGGTCATCGCGGGCTGGGATGAAGGCATCGCCGGCATGCGCGTGGGGAGCCGTCGTCGCCTCATCATCCC
GTCGTCCCTGGGTTATGGCGCCACCGGCTCGGGCAGACGGATTCCGCCGTACACGGTCCTCATCTTCGACACCGAGCTCG
TGTCCGTCCGCTGA

Upstream 100 bases:

>100_bases
CGCTTCGTCACGTCACGGACGAGCCGACGGTAGAGATAGACATGGCCCACCGACAGTACGGCGAGCACGGGAATGAAGAA
GAGGAGCAGGCTGACCCAGC

Downstream 100 bases:

>100_bases
CGGAGGCGAGGAACTCCGCTCGCCGACGTGCTATAGGATTTCCTTGTCTTCCGGGAAGTTCGGGTCGGCGTGGACCGGCC
TGGATGTTCGTGGTGACCCG

Product: FKBP-type peptidylprolyl cis-trans isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase; PPIase; Rotamase [H]

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MASGILHNECVPAALQDSRGAGGKAAWAHPWPLSHAAAPGQASPSREADSRFTHPFEVVMLRSLLVPMLLAVSLLGCGDD
ESVNPDSGDPTKVTYAESLNVDLAEMTRLESGLYIQDTFVVEDGAQAEAGKRVQVRYTGYLPDGRSFDATGNGPAIGFTL
GVGQVIAGWDEGIAGMRVGSRRRLIIPSSLGYGATGSGRRIPPYTVLIFDTELVSVR

Sequences:

>Translated_217_residues
MASGILHNECVPAALQDSRGAGGKAAWAHPWPLSHAAAPGQASPSREADSRFTHPFEVVMLRSLLVPMLLAVSLLGCGDD
ESVNPDSGDPTKVTYAESLNVDLAEMTRLESGLYIQDTFVVEDGAQAEAGKRVQVRYTGYLPDGRSFDATGNGPAIGFTL
GVGQVIAGWDEGIAGMRVGSRRRLIIPSSLGYGATGSGRRIPPYTVLIFDTELVSVR
>Mature_216_residues
ASGILHNECVPAALQDSRGAGGKAAWAHPWPLSHAAAPGQASPSREADSRFTHPFEVVMLRSLLVPMLLAVSLLGCGDDE
SVNPDSGDPTKVTYAESLNVDLAEMTRLESGLYIQDTFVVEDGAQAEAGKRVQVRYTGYLPDGRSFDATGNGPAIGFTLG
VGQVIAGWDEGIAGMRVGSRRRLIIPSSLGYGATGSGRRIPPYTVLIFDTELVSVR

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG0545

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1

Gene ontology:

Cell location: Cytoplasm And Periplasmic Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Homo sapiens, GI8923659, Length=107, Percent_Identity=42.9906542056075, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI206725530, Length=93, Percent_Identity=44.0860215053763, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI17149844, Length=93, Percent_Identity=44.0860215053763, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI17149842, Length=93, Percent_Identity=44.0860215053763, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI17149836, Length=88, Percent_Identity=44.3181818181818, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI4503725, Length=88, Percent_Identity=44.3181818181818, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI192448443, Length=92, Percent_Identity=40.2173913043478, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI4503729, Length=89, Percent_Identity=40.4494382022472, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI4758380, Length=91, Percent_Identity=40.6593406593407, Blast_Score=67, Evalue=9e-12,
Organism=Homo sapiens, GI33469985, Length=91, Percent_Identity=39.5604395604396, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI150010552, Length=105, Percent_Identity=35.2380952380952, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI87082390, Length=127, Percent_Identity=38.5826771653543, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17540882, Length=92, Percent_Identity=44.5652173913043, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71993519, Length=94, Percent_Identity=36.1702127659575, Blast_Score=67, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17561782, Length=86, Percent_Identity=43.0232558139535, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323566, Length=128, Percent_Identity=41.40625, Blast_Score=92, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6320727, Length=100, Percent_Identity=52, Blast_Score=89, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6323482, Length=109, Percent_Identity=44.0366972477064, Blast_Score=87, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6324194, Length=97, Percent_Identity=43.298969072165, Blast_Score=74, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281363946, Length=93, Percent_Identity=44.0860215053763, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI17352457, Length=93, Percent_Identity=44.0860215053763, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24647110, Length=107, Percent_Identity=42.9906542056075, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21356629, Length=93, Percent_Identity=47.3118279569892, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24655568, Length=91, Percent_Identity=43.956043956044, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24583150, Length=88, Percent_Identity=42.0454545454545, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 22942; Mature: 22811

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASGILHNECVPAALQDSRGAGGKAAWAHPWPLSHAAAPGQASPSREADSRFTHPFEVVM
CCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
LRSLLVPMLLAVSLLGCGDDESVNPDSGDPTKVTYAESLNVDLAEMTRLESGLYIQDTFV
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCEEEEEEE
VEDGAQAEAGKRVQVRYTGYLPDGRSFDATGNGPAIGFTLGVGQVIAGWDEGIAGMRVGS
EECCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCEEEEEECCCHHHHCCCCCCCCEEECC
RRRLIIPSSLGYGATGSGRRIPPYTVLIFDTELVSVR
CCEEEEECCCCCCCCCCCCCCCCEEEEEEECEEEECC
>Mature Secondary Structure 
ASGILHNECVPAALQDSRGAGGKAAWAHPWPLSHAAAPGQASPSREADSRFTHPFEVVM
CCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
LRSLLVPMLLAVSLLGCGDDESVNPDSGDPTKVTYAESLNVDLAEMTRLESGLYIQDTFV
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCEEEEEEE
VEDGAQAEAGKRVQVRYTGYLPDGRSFDATGNGPAIGFTLGVGQVIAGWDEGIAGMRVGS
EECCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCEEEEEECCCHHHHCCCCCCCCEEECC
RRRLIIPSSLGYGATGSGRRIPPYTVLIFDTELVSVR
CCEEEEECCCCCCCCCCCCCCCCEEEEEEECEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]